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The map label for this gene is aroG2 [H]

Identifier: 89898792

GI number: 89898792

Start: 1134639

End: 1135448

Strand: Direct

Name: aroG2 [H]

Synonym: CF0985

Alternate gene names: 89898792

Gene position: 1134639-1135448 (Clockwise)

Preceding gene: 89898791

Following gene: 89898793

Centisome position: 97.29

GC content: 43.58

Gene sequence:

>810_bases
ATGTTCTCAGACAAGATGATCCTCATTGCCGGCCCTTGTGTCATAGAGGGAGAAGAAATTACGCTAGAAATAGCTTCAAA
AATCCACGAACTTGTTTCTCCCTATGCGGATCGCATTCATTGGATTTTCAAAAGTAGCTACGACAAAGCGAATCGTTCCT
CTATAAATTCTTATCGAGGCCCGGGATTAAGCGAAGGCCTAAGAATCCTGTCCAAGGTTAAAGAAACTTTAGGAGTGGAA
ATTCTTACAGATGTGCATTCTCCTGAAGAAGCCCGCGCAGCTGCCGAGGTTTGTGATATTCTTCAAATTCCAGCATTTTT
ATGCCGACAAACCGATCTTCTTGTTGCCGCTGCTGAAACAAACGCTATTATCAATATTAAAAAAGGGCAATTTCTCTCTC
CTTGGGATATGCAAGGCCCTGTGGACAAAGTCCTCTCTACAGGAAACAATAAGATTATTTTGACTGAAAGAGGGTGCTCT
TTTGGCTATAACAATCTTGTTTCGGATATGCGTTCCATTCCTGTTCTTTCGAGCATGGGTTTTCCCGTTGTTTTTGACGG
AACACATTCCGTTCAACTTCCCGGCGGGTTAAAAACCCAAAGTGGCGGACAAACAGAATTTATTCCCACATTAACACGAG
CTGCCCTAGCCGCAGGAGCGCACGGTCTGTTCATAGAAACGCATTCCCATCCTGCTATAGCCAAAAGTGACGCGGCCTCT
ATGTTACCATTAAAGACTTTTGAAGCTCTTCTTCCTCTATGGGATCAGCTATATACTTGTGTACGTTCATTTGAGATGGC
TTCAGTATGA

Upstream 100 bases:

>100_bases
TGTGTTCCTCGAAGAGCGTTCTCTTCTTAAAATCGTAGGTGGACTTGTTTCAAATAAACCTCTATAGTGGCTTTTTAACG
GAAGAAAAAGGGTGCTTACG

Downstream 100 bases:

>100_bases
CTAAATTCTTGTTCTACGGCTTGTTATGTTCTTTAGGGATATTTGGCATAGCTTGCACAACAATTGTCGCTATAATCAAA
GTAGACAGCATTTGCGATGT

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MFSDKMILIAGPCVIEGEEITLEIASKIHELVSPYADRIHWIFKSSYDKANRSSINSYRGPGLSEGLRILSKVKETLGVE
ILTDVHSPEEARAAAEVCDILQIPAFLCRQTDLLVAAAETNAIINIKKGQFLSPWDMQGPVDKVLSTGNNKIILTERGCS
FGYNNLVSDMRSIPVLSSMGFPVVFDGTHSVQLPGGLKTQSGGQTEFIPTLTRAALAAGAHGLFIETHSHPAIAKSDAAS
MLPLKTFEALLPLWDQLYTCVRSFEMASV

Sequences:

>Translated_269_residues
MFSDKMILIAGPCVIEGEEITLEIASKIHELVSPYADRIHWIFKSSYDKANRSSINSYRGPGLSEGLRILSKVKETLGVE
ILTDVHSPEEARAAAEVCDILQIPAFLCRQTDLLVAAAETNAIINIKKGQFLSPWDMQGPVDKVLSTGNNKIILTERGCS
FGYNNLVSDMRSIPVLSSMGFPVVFDGTHSVQLPGGLKTQSGGQTEFIPTLTRAALAAGAHGLFIETHSHPAIAKSDAAS
MLPLKTFEALLPLWDQLYTCVRSFEMASV
>Mature_269_residues
MFSDKMILIAGPCVIEGEEITLEIASKIHELVSPYADRIHWIFKSSYDKANRSSINSYRGPGLSEGLRILSKVKETLGVE
ILTDVHSPEEARAAAEVCDILQIPAFLCRQTDLLVAAAETNAIINIKKGQFLSPWDMQGPVDKVLSTGNNKIILTERGCS
FGYNNLVSDMRSIPVLSSMGFPVVFDGTHSVQLPGGLKTQSGGQTEFIPTLTRAALAAGAHGLFIETHSHPAIAKSDAAS
MLPLKTFEALLPLWDQLYTCVRSFEMASV

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=262, Percent_Identity=45.0381679389313, Blast_Score=231, Evalue=4e-62,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 29235; Mature: 29235

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSDKMILIAGPCVIEGEEITLEIASKIHELVSPYADRIHWIFKSSYDKANRSSINSYRG
CCCCCEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCHHCCC
PGLSEGLRILSKVKETLGVEILTDVHSPEEARAAAEVCDILQIPAFLCRQTDLLVAAAET
CCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
NAIINIKKGQFLSPWDMQGPVDKVLSTGNNKIILTERGCSFGYNNLVSDMRSIPVLSSMG
CEEEEECCCCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHCCC
FPVVFDGTHSVQLPGGLKTQSGGQTEFIPTLTRAALAAGAHGLFIETHSHPAIAKSDAAS
CCEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHH
MLPLKTFEALLPLWDQLYTCVRSFEMASV
HCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSDKMILIAGPCVIEGEEITLEIASKIHELVSPYADRIHWIFKSSYDKANRSSINSYRG
CCCCCEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCHHCCC
PGLSEGLRILSKVKETLGVEILTDVHSPEEARAAAEVCDILQIPAFLCRQTDLLVAAAET
CCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
NAIINIKKGQFLSPWDMQGPVDKVLSTGNNKIILTERGCSFGYNNLVSDMRSIPVLSSMG
CEEEEECCCCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHCCC
FPVVFDGTHSVQLPGGLKTQSGGQTEFIPTLTRAALAAGAHGLFIETHSHPAIAKSDAAS
CCEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHH
MLPLKTFEALLPLWDQLYTCVRSFEMASV
HCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA