Click here to switch to the map view.

The map label for this gene is yaeS [H]

Identifier: 89898638

GI number: 89898638

Start: 981401

End: 982153

Strand: Direct

Name: yaeS [H]

Synonym: CF0831

Alternate gene names: 89898638

Gene position: 981401-982153 (Clockwise)

Preceding gene: 89898630

Following gene: 89898639

Centisome position: 84.15

GC content: 40.5

Gene sequence:

>753_bases
ATGTCTCTCACCTTAAAACAGGCGGATCAAGCTGATCCATCAACGCAGTCTCTACCGAGGCATGTAGCCATTATTATGGA
TGGCAATCGTCGTTGGTATCAGCGACATCAAATACTAAGATCTATCCAACATTCCTCAGGGCATCATTACGGAGCCAAAG
CCCTGCCTGATATTATTGAATCTGCGTTTTCTTTAGGTATTGAGGTTCTCACTTTATTTGCTTTTTCTACAGAGAATTTT
CTCAGGTCAACTGAAGAGGTTGAAGAACTTTTTTCTCTTTTCCATTCCCAACTGGATGAGCAGCTTCCCCATCTTATTGA
AAATAAAATCCGTCTGCGCTGTATAGGGAACCTGCTAGCTTTACCTAAACACCTACAACAACAAATTGCTAAGATTACAT
CGCAAACTAAGGAATATTCGGGAAGAGAACTTGTTTTAGCAATTAATTATGGCGGGAAAGACGAACTTGTACGCGCGTTT
AAGAAACTGCATCAAGATTTATCAGATCAAAAAATATCTTTAGACTCTGTTTCAGAGGGGTTGATCCGCTTGTATTTAGA
TACCTCAGAAATCCCTGATCCTGATTTATTAATTCGCACTGGTGGCGAAATGCGTGTCAGTAATTTTCTCTTGTGGCAAA
TAGCATATACAGAGCTATATGTAACTGATGTTTTATGGCCGGATTTTAAACCCGATCATCTTCTAGATGCTATTAAAGCT
TACCAACACAGAGCGCGACGAGGAGGCAGGTAG

Upstream 100 bases:

>100_bases
CCTACAAGGCTTTTTATCTACGATTTTAGCTTAAAAAGGGGTTTATCTGTTGTCTTTGAAACCAAGCCATAACTCACACT
GCACAACTAACGATGTAAAT

Downstream 100 bases:

>100_bases
CCATGTTGAAACTGAATAAGTTTAAAACTCCTTTCTATGGGGATCTTTTCCAACGAGTTGTTGTACATTCGTTGGTTCTT
ACATTCTTGGTACTTCTTCT

Product: undecaprenyl pyrophosphate synthase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSLTLKQADQADPSTQSLPRHVAIIMDGNRRWYQRHQILRSIQHSSGHHYGAKALPDIIESAFSLGIEVLTLFAFSTENF
LRSTEEVEELFSLFHSQLDEQLPHLIENKIRLRCIGNLLALPKHLQQQIAKITSQTKEYSGRELVLAINYGGKDELVRAF
KKLHQDLSDQKISLDSVSEGLIRLYLDTSEIPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFKPDHLLDAIKA
YQHRARRGGR

Sequences:

>Translated_250_residues
MSLTLKQADQADPSTQSLPRHVAIIMDGNRRWYQRHQILRSIQHSSGHHYGAKALPDIIESAFSLGIEVLTLFAFSTENF
LRSTEEVEELFSLFHSQLDEQLPHLIENKIRLRCIGNLLALPKHLQQQIAKITSQTKEYSGRELVLAINYGGKDELVRAF
KKLHQDLSDQKISLDSVSEGLIRLYLDTSEIPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFKPDHLLDAIKA
YQHRARRGGR
>Mature_249_residues
SLTLKQADQADPSTQSLPRHVAIIMDGNRRWYQRHQILRSIQHSSGHHYGAKALPDIIESAFSLGIEVLTLFAFSTENFL
RSTEEVEELFSLFHSQLDEQLPHLIENKIRLRCIGNLLALPKHLQQQIAKITSQTKEYSGRELVLAINYGGKDELVRAFK
KLHQDLSDQKISLDSVSEGLIRLYLDTSEIPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFKPDHLLDAIKAY
QHRARRGGR

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580742, Length=228, Percent_Identity=35.9649122807018, Blast_Score=143, Evalue=1e-34,
Organism=Homo sapiens, GI45580738, Length=228, Percent_Identity=35.9649122807018, Blast_Score=143, Evalue=1e-34,
Organism=Escherichia coli, GI1786371, Length=241, Percent_Identity=41.49377593361, Blast_Score=187, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI71993029, Length=230, Percent_Identity=37.3913043478261, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319474, Length=223, Percent_Identity=32.7354260089686, Blast_Score=115, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6323748, Length=218, Percent_Identity=27.9816513761468, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18857969, Length=228, Percent_Identity=39.0350877192982, Blast_Score=152, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 28699; Mature: 28568

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTLKQADQADPSTQSLPRHVAIIMDGNRRWYQRHQILRSIQHSSGHHYGAKALPDIIE
CCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
SAFSLGIEVLTLFAFSTENFLRSTEEVEELFSLFHSQLDEQLPHLIENKIRLRCIGNLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPKHLQQQIAKITSQTKEYSGRELVLAINYGGKDELVRAFKKLHQDLSDQKISLDSVSEG
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHCC
LIRLYLDTSEIPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFKPDHLLDAIKA
CEEEEECCCCCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
YQHRARRGGR
HHHHHHCCCC
>Mature Secondary Structure 
SLTLKQADQADPSTQSLPRHVAIIMDGNRRWYQRHQILRSIQHSSGHHYGAKALPDIIE
CCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
SAFSLGIEVLTLFAFSTENFLRSTEEVEELFSLFHSQLDEQLPHLIENKIRLRCIGNLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPKHLQQQIAKITSQTKEYSGRELVLAINYGGKDELVRAFKKLHQDLSDQKISLDSVSEG
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHCC
LIRLYLDTSEIPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFKPDHLLDAIKA
CEEEEECCCCCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
YQHRARRGGR
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA