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The map label for this gene is lspA

Identifier: 89898604

GI number: 89898604

Start: 938344

End: 938841

Strand: Direct

Name: lspA

Synonym: CF0797

Alternate gene names: 89898604

Gene position: 938344-938841 (Clockwise)

Preceding gene: 89898603

Following gene: 89898605

Centisome position: 80.46

GC content: 35.34

Gene sequence:

>498_bases
ATGTCCAACCGCTCCCGATCTACCCTCCTTACTATTTCCTTTTTCGTCCTTATTGATTGGGTGACCAAATTAGCCGTTTT
GCTGTACCGTGGAAATCTGCCGAATGCTAACCCCATACTATACCAATATAGTTGGGGGAAGCTATTTTTCTGCATTTGCC
CCACTTTTAATGAAGGCGCTGCTTTTGGATTATTTTCAAAATATAAATATTTCTTACTTCTTATACGTATAGTAATTATT
TTAGGCATTCTTGCTTTCCTTTTCTTAAGAAAGAAAAAAACCTCTGCAACTACCCGTTTCTCGCTGATTCTCCTGTGTTC
TGGAGCCATAGGCAACGTTGGAGATATTTTTTTCTACAATCATGTTATAGATTTTATTTCTATTGGTTATAATCGTTGGT
CTTTCCCCACTTTTAATTTCGCCGATATTTTTATCTCCTTAGGAACTTTAATCTTCGTATATAAGCTTTATTTTCCTACT
AAACAAAAGATAAAATAG

Upstream 100 bases:

>100_bases
AAATCCCTCTAGCTCGTTTGATGGCGATCCCTTACGCCACGATGACGGTCAAAGCTCAATCGCAATTTGAGAAAGGGCTA
CTTTACGGAAACTAATCCCA

Downstream 100 bases:

>100_bases
GGATAATAAATACCCTATCTTTCTGAAGAATAACTGTTTTTACCCCAATAAAAAAAGTTTTACCATGAACGCAATCCTAT
CTTTGCTAGCAGCCTTTGAC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSNRSRSTLLTISFFVLIDWVTKLAVLLYRGNLPNANPILYQYSWGKLFFCICPTFNEGAAFGLFSKYKYFLLLIRIVII
LGILAFLFLRKKKTSATTRFSLILLCSGAIGNVGDIFFYNHVIDFISIGYNRWSFPTFNFADIFISLGTLIFVYKLYFPT
KQKIK

Sequences:

>Translated_165_residues
MSNRSRSTLLTISFFVLIDWVTKLAVLLYRGNLPNANPILYQYSWGKLFFCICPTFNEGAAFGLFSKYKYFLLLIRIVII
LGILAFLFLRKKKTSATTRFSLILLCSGAIGNVGDIFFYNHVIDFISIGYNRWSFPTFNFADIFISLGTLIFVYKLYFPT
KQKIK
>Mature_164_residues
SNRSRSTLLTISFFVLIDWVTKLAVLLYRGNLPNANPILYQYSWGKLFFCICPTFNEGAAFGLFSKYKYFLLLIRIVIIL
GILAFLFLRKKKTSATTRFSLILLCSGAIGNVGDIFFYNHVIDFISIGYNRWSFPTFNFADIFISLGTLIFVYKLYFPTK
QKIK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LSPA_CHLFF (Q253G9)

Other databases:

- EMBL:   AP006861
- RefSeq:   YP_515714.1
- STRING:   Q253G9
- GeneID:   3958329
- GenomeReviews:   AP006861_GR
- KEGG:   cfe:CF0797
- eggNOG:   COG0597
- HOGENOM:   HBG724422
- OMA:   GSIGNII
- ProtClustDB:   PRK00376
- BioCyc:   CFEL264202:CF0797-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_00161
- InterPro:   IPR001872
- PRINTS:   PR00781
- TIGRFAMs:   TIGR00077

Pfam domain/function: PF01252 Peptidase_A8

EC number: =3.4.23.36

Molecular weight: Translated: 19070; Mature: 18939

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS00855 SPASE_II

Important sites: ACT_SITE 115-115 ACT_SITE 142-142

Signals:

None

Transmembrane regions:

HASH(0x20d5ff48)-; HASH(0x221ad7a8)-; HASH(0x21f11a8c)-; HASH(0x21742628)-;

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRSRSTLLTISFFVLIDWVTKLAVLLYRGNLPNANPILYQYSWGKLFFCICPTFNEGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCCCCCC
AFGLFSKYKYFLLLIRIVIILGILAFLFLRKKKTSATTRFSLILLCSGAIGNVGDIFFYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEEECCCCCCHHHHHHHH
HVIDFISIGYNRWSFPTFNFADIFISLGTLIFVYKLYFPTKQKIK
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCH
>Mature Secondary Structure 
SNRSRSTLLTISFFVLIDWVTKLAVLLYRGNLPNANPILYQYSWGKLFFCICPTFNEGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCCCCCC
AFGLFSKYKYFLLLIRIVIILGILAFLFLRKKKTSATTRFSLILLCSGAIGNVGDIFFYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEEECCCCCCHHHHHHHH
HVIDFISIGYNRWSFPTFNFADIFISLGTLIFVYKLYFPTKQKIK
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA