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The map label for this gene is aroG1 [H]

Identifier: 89898555

GI number: 89898555

Start: 890181

End: 891041

Strand: Direct

Name: aroG1 [H]

Synonym: CF0748

Alternate gene names: 89898555

Gene position: 890181-891041 (Clockwise)

Preceding gene: 89898554

Following gene: 89898556

Centisome position: 76.33

GC content: 43.79

Gene sequence:

>861_bases
ATTCTTACGACGACTCATCCTCTACCTTATTCGATAAAACGATCTTTGGAAGACCCCAGTACCATTCTTCCCCTATCTTC
AGAAGTCTCCGTTGGGGGAGGGTCTCCGCTCCTCATCGCAGGCCCATGCACTTTAGAAAGTTATGAGCATACCGTAGCTA
TCGGCCTTGCAGCTAAAGCGGCGGGCGCTACAGTGTTGCGAGGATCTATACGAAAACCTCGAACTAGTCCCTACTCCTTT
CAGGGATGGGAAAAAGAGTGCGTTATCTGGCATAAAGAAGCTCAACGTATTCATGGCTTGCTGACAGAAACAGAAGTTTT
AGATGTGCGTGATGTAGAAATCACAGCGGAAAACGTCGATATTCTTCGTATAGGCGCAAGAAACATGCAAAACTTTGTTT
TGCTGCAAGAAGCCAGTCAAAGTCATCGTCCGATTATTCTCAAACGTCATCCCTCAGCAACTATAGAAGAGTGGCTATCT
TCTGCTGAATATCTTCTAAACTCGCCCTCATGTCCTGGGGTAATTCTTTGCGAAAGAGGTATTCGAACTTTTGAAATGTC
CACACGCTACACTCTCGATCTCAATACCGTAGCTCTGCTAAAAGAAATCAGCCCTCTTCCAGTCATTGTTGATCCCTCTC
ATGCTGCAGGAAAACGCTCTTTGGTAGCTCCATTAGCAAAAGCTGCCATGGCTGTGGGAGCTGATGGATTAATAATAGAA
ATGCATGAATGTCCAGAAAAAGCTCTTTGTGATGGGAAACAACACATAACACCAGAAGAGCTTAGTGAAGTATTTTCATC
TATTATTAATCATAGTCGATCAAAGAAAGGAGAACAACACGCGGATTTGATTTATCAATAA

Upstream 100 bases:

>100_bases
ATCACTATAACTGCTTACTGCCGAAAGATGCTAATGATACTTCGAAAGCAGAAAATGCAGGAAGTCCATCGAATCCATAA
TAAACTAGGGGGGCTTACTT

Downstream 100 bases:

>100_bases
ATCGCATAAACCCCACTGTCTCCCTATTAAATTCTAAAAAACCCAAGATCCTTTATCATGTGTAGAGTCACACCATAAAA
TCTCGGATTTTATTTAATTA

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLTTTHPLPYSIKRSLEDPSTILPLSSEVSVGGGSPLLIAGPCTLESYEHTVAIGLAAKAAGATVLRGSIRKPRTSPYSF
QGWEKECVIWHKEAQRIHGLLTETEVLDVRDVEITAENVDILRIGARNMQNFVLLQEASQSHRPIILKRHPSATIEEWLS
SAEYLLNSPSCPGVILCERGIRTFEMSTRYTLDLNTVALLKEISPLPVIVDPSHAAGKRSLVAPLAKAAMAVGADGLIIE
MHECPEKALCDGKQHITPEELSEVFSSIINHSRSKKGEQHADLIYQ

Sequences:

>Translated_286_residues
MLTTTHPLPYSIKRSLEDPSTILPLSSEVSVGGGSPLLIAGPCTLESYEHTVAIGLAAKAAGATVLRGSIRKPRTSPYSF
QGWEKECVIWHKEAQRIHGLLTETEVLDVRDVEITAENVDILRIGARNMQNFVLLQEASQSHRPIILKRHPSATIEEWLS
SAEYLLNSPSCPGVILCERGIRTFEMSTRYTLDLNTVALLKEISPLPVIVDPSHAAGKRSLVAPLAKAAMAVGADGLIIE
MHECPEKALCDGKQHITPEELSEVFSSIINHSRSKKGEQHADLIYQ
>Mature_286_residues
MLTTTHPLPYSIKRSLEDPSTILPLSSEVSVGGGSPLLIAGPCTLESYEHTVAIGLAAKAAGATVLRGSIRKPRTSPYSF
QGWEKECVIWHKEAQRIHGLLTETEVLDVRDVEITAENVDILRIGARNMQNFVLLQEASQSHRPIILKRHPSATIEEWLS
SAEYLLNSPSCPGVILCERGIRTFEMSTRYTLDLNTVALLKEISPLPVIVDPSHAAGKRSLVAPLAKAAMAVGADGLIIE
MHECPEKALCDGKQHITPEELSEVFSSIINHSRSKKGEQHADLIYQ

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=234, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 31313; Mature: 31313

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTTHPLPYSIKRSLEDPSTILPLSSEVSVGGGSPLLIAGPCTLESYEHTVAIGLAAKA
CCCCCCCCCHHHHHCCCCCCEEECCCCCEECCCCCEEEEECCCCCCCCCCEEEEEEHHHH
AGATVLRGSIRKPRTSPYSFQGWEKECVIWHKEAQRIHGLLTETEVLDVRDVEITAENVD
CCHHHHHCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEEEEEEEECCEE
ILRIGARNMQNFVLLQEASQSHRPIILKRHPSATIEEWLSSAEYLLNSPSCPGVILCERG
EEEECCCCCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCC
IRTFEMSTRYTLDLNTVALLKEISPLPVIVDPSHAAGKRSLVAPLAKAAMAVGADGLIIE
CEEEEECEEEEEECHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
MHECPEKALCDGKQHITPEELSEVFSSIINHSRSKKGEQHADLIYQ
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MLTTTHPLPYSIKRSLEDPSTILPLSSEVSVGGGSPLLIAGPCTLESYEHTVAIGLAAKA
CCCCCCCCCHHHHHCCCCCCEEECCCCCEECCCCCEEEEECCCCCCCCCCEEEEEEHHHH
AGATVLRGSIRKPRTSPYSFQGWEKECVIWHKEAQRIHGLLTETEVLDVRDVEITAENVD
CCHHHHHCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEEEEEEEECCEE
ILRIGARNMQNFVLLQEASQSHRPIILKRHPSATIEEWLSSAEYLLNSPSCPGVILCERG
EEEECCCCCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCC
IRTFEMSTRYTLDLNTVALLKEISPLPVIVDPSHAAGKRSLVAPLAKAAMAVGADGLIIE
CEEEEECEEEEEECHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
MHECPEKALCDGKQHITPEELSEVFSSIINHSRSKKGEQHADLIYQ
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]