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The map label for this gene is acpS

Identifier: 89898345

GI number: 89898345

Start: 632784

End: 633152

Strand: Direct

Name: acpS

Synonym: CF0538

Alternate gene names: 89898345

Gene position: 632784-633152 (Clockwise)

Preceding gene: 89898344

Following gene: 89898347

Centisome position: 54.26

GC content: 40.65

Gene sequence:

>369_bases
ATGCAAATGGCTCATATTGGAACAGATATTATTGAAATTGCTCGAATCCGCAAAGCAATAGAGACCCACAACCAAAGAAT
GTTAAATAAAATTTTCACTAAAAAAGAACAGGAGTATTGTTTAAGGCTAACAAACCCCTACCCCTCCTTTGCTGCAAGAT
TCGCAGGGAAAGAAGCCGTAGCCAAAGCTTTGGGGACTGGAATCGGAAAAGTCATTGGCTGGAAAGATATAGAGATTCTT
ACATCACCCAAACAACCCAAAGTCCATTTACCCCCAAGAGTATATAAAGAACTAGGAATTTCCAAAGTCTTACTATCAAT
CAGCCATAGCCGCGAATACGCTACAGCCATGGCTGTAGCTCTAGTCTAA

Upstream 100 bases:

>100_bases
TCGCTCCACTATAGGCTATGCTCTTATTAAAACAGCTTTGACTTACTTCGCTAAATCCCACAAAACACTCTTAGAAAGCC
TTTAACCTCAGATATTCATT

Downstream 100 bases:

>100_bases
AAAACGCTCAGCTTCTAAAGCTGCCATACAGCCACTTCCCGCTGCCGTGATGGCTTGCCGGTAATATTTATCTTGAACAT
CCCCAGCAGCAAATACCCCA

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MQMAHIGTDIIEIARIRKAIETHNQRMLNKIFTKKEQEYCLRLTNPYPSFAARFAGKEAVAKALGTGIGKVIGWKDIEIL
TSPKQPKVHLPPRVYKELGISKVLLSISHSREYATAMAVALV

Sequences:

>Translated_122_residues
MQMAHIGTDIIEIARIRKAIETHNQRMLNKIFTKKEQEYCLRLTNPYPSFAARFAGKEAVAKALGTGIGKVIGWKDIEIL
TSPKQPKVHLPPRVYKELGISKVLLSISHSREYATAMAVALV
>Mature_122_residues
MQMAHIGTDIIEIARIRKAIETHNQRMLNKIFTKKEQEYCLRLTNPYPSFAARFAGKEAVAKALGTGIGKVIGWKDIEIL
TSPKQPKVHLPPRVYKELGISKVLLSISHSREYATAMAVALV

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=123, Percent_Identity=30.8943089430894, Blast_Score=63, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_CHLFF (Q254H8)

Other databases:

- EMBL:   AP006861
- RefSeq:   YP_515455.1
- ProteinModelPortal:   Q254H8
- SMR:   Q254H8
- STRING:   Q254H8
- GeneID:   3958645
- GenomeReviews:   AP006861_GR
- KEGG:   cfe:CF0538
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   HIGTDII
- ProtClustDB:   PRK00070
- BioCyc:   CFEL264202:CF0538-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13657; Mature: 13657

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMAHIGTDIIEIARIRKAIETHNQRMLNKIFTKKEQEYCLRLTNPYPSFAARFAGKEAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHCCHHHH
AKALGTGIGKVIGWKDIEILTSPKQPKVHLPPRVYKELGISKVLLSISHSREYATAMAVA
HHHHHHHHHHHCCCCCCEEEECCCCCCEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LV
CC
>Mature Secondary Structure
MQMAHIGTDIIEIARIRKAIETHNQRMLNKIFTKKEQEYCLRLTNPYPSFAARFAGKEAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHCCHHHH
AKALGTGIGKVIGWKDIEILTSPKQPKVHLPPRVYKELGISKVLLSISHSREYATAMAVA
HHHHHHHHHHHCCCCCCEEEECCCCCCEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA