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The map label for this gene is surE

Identifier: 89898295

GI number: 89898295

Start: 573699

End: 574523

Strand: Direct

Name: surE

Synonym: CF0488

Alternate gene names: 89898295

Gene position: 573699-574523 (Clockwise)

Preceding gene: 89898294

Following gene: 89898296

Centisome position: 49.19

GC content: 38.91

Gene sequence:

>825_bases
ATGAATAAAAAATTAAAGGTTTTGTTAACTAACGATGACGGGATTTTTGCGAAAGGGATAAGTCTGTTAGTTTCTAACTT
ACTAAAAGCCGATTTTGCTGATCTGTATATAGTTGCTCCTAATACGGAACAGTCGGGGAAGAGCATGTCTTTTTCTTATA
CAGAACCCGTCTCTATCGAACGCGTTGACTACCACCAACCTGTCGCAGGTGCTTGGGCAGTTTCTGGCAGCCCAGTGGAT
TGCATCAAGCTTGCTCTTGGAGACTTATTCTTAGACTCATTACCAGATATTGTCTTGTCAGGAATTAATAACGGATCTAA
TGCAGGAAGAAATATTTTTTACTCCGGAACTGCGGGAGCGGCTATGGAAGCTGTTATATCAGGTATTCCTGCAATAGCTT
TTTCTCAAGAAGAGCACATATCCTGCTTTCAAGAAAAAAAATCTTGTGAACTAATAAAAATGCTAGTTCTTTATGCTTTA
TCCAGGCCTTTTCCTCTCCTGACTGGGTTTAATGTCAATTTCCCTGCATGTGAAAATAATGAAGAATGGCAGGGTATGAA
GCTTGTAGCCACAGGAAAAGAGTTTGCCTATGGTGTGCCAAGACTTCTATGCGATGACGGAAAACGCAAGTTCTATTCTT
TAAATGATTGTCAAAGATTGATGGACGAAGATCTTTCTGAGGAGTGTCACTCTCTTTTGACAAAAAAAATTACAGTAGCA
CCTTTATTGGTAAGAAATTCTCCTCTAGGTTTAATGAGTGAGGAAGAATTTCAACAGTTACAACAAGAGTTTGAGGATTT
TATTCACTCTGAAATCCGGAGTTAA

Upstream 100 bases:

>100_bases
TTTTTTTATGGATAAAAAATAAAAACTAGTTGAATGTTCTTTTCATGGATTAACCTCGCTTTTTTTTAATTATGGTGATG
TTTGTTTTTTTGGTAATGAT

Downstream 100 bases:

>100_bases
ACTTTTTGATCGTTAATATGAATTCTTTGATCTAGTCCCTATTAAGAGAACATCAGTCCCCTGACATGCGATTAATTTCA
AACATTTGGAATGAACAAGA

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MNKKLKVLLTNDDGIFAKGISLLVSNLLKADFADLYIVAPNTEQSGKSMSFSYTEPVSIERVDYHQPVAGAWAVSGSPVD
CIKLALGDLFLDSLPDIVLSGINNGSNAGRNIFYSGTAGAAMEAVISGIPAIAFSQEEHISCFQEKKSCELIKMLVLYAL
SRPFPLLTGFNVNFPACENNEEWQGMKLVATGKEFAYGVPRLLCDDGKRKFYSLNDCQRLMDEDLSEECHSLLTKKITVA
PLLVRNSPLGLMSEEEFQQLQQEFEDFIHSEIRS

Sequences:

>Translated_274_residues
MNKKLKVLLTNDDGIFAKGISLLVSNLLKADFADLYIVAPNTEQSGKSMSFSYTEPVSIERVDYHQPVAGAWAVSGSPVD
CIKLALGDLFLDSLPDIVLSGINNGSNAGRNIFYSGTAGAAMEAVISGIPAIAFSQEEHISCFQEKKSCELIKMLVLYAL
SRPFPLLTGFNVNFPACENNEEWQGMKLVATGKEFAYGVPRLLCDDGKRKFYSLNDCQRLMDEDLSEECHSLLTKKITVA
PLLVRNSPLGLMSEEEFQQLQQEFEDFIHSEIRS
>Mature_274_residues
MNKKLKVLLTNDDGIFAKGISLLVSNLLKADFADLYIVAPNTEQSGKSMSFSYTEPVSIERVDYHQPVAGAWAVSGSPVD
CIKLALGDLFLDSLPDIVLSGINNGSNAGRNIFYSGTAGAAMEAVISGIPAIAFSQEEHISCFQEKKSCELIKMLVLYAL
SRPFPLLTGFNVNFPACENNEEWQGMKLVATGKEFAYGVPRLLCDDGKRKFYSLNDCQRLMDEDLSEECHSLLTKKITVA
PLLVRNSPLGLMSEEEFQQLQQEFEDFIHSEIRS

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=174, Percent_Identity=37.3563218390805, Blast_Score=95, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_CHLFF (Q254M8)

Other databases:

- EMBL:   AP006861
- RefSeq:   YP_515405.1
- ProteinModelPortal:   Q254M8
- SMR:   Q254M8
- STRING:   Q254M8
- GeneID:   3959090
- GenomeReviews:   AP006861_GR
- KEGG:   cfe:CF0488
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   SNAGRNI
- ProtClustDB:   PRK00346
- BioCyc:   CFEL264202:CF0488-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 30277; Mature: 30277

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLKVLLTNDDGIFAKGISLLVSNLLKADFADLYIVAPNTEQSGKSMSFSYTEPVSIE
CCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEECCCCCEEE
RVDYHQPVAGAWAVSGSPVDCIKLALGDLFLDSLPDIVLSGINNGSNAGRNIFYSGTAGA
ECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHH
AMEAVISGIPAIAFSQEEHISCFQEKKSCELIKMLVLYALSRPFPLLTGFNVNFPACENN
HHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
EEWQGMKLVATGKEFAYGVPRLLCDDGKRKFYSLNDCQRLMDEDLSEECHSLLTKKITVA
CCCCCEEEEECCCHHHHCCCHHHHCCCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLVRNSPLGLMSEEEFQQLQQEFEDFIHSEIRS
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKKLKVLLTNDDGIFAKGISLLVSNLLKADFADLYIVAPNTEQSGKSMSFSYTEPVSIE
CCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEECCCCCEEE
RVDYHQPVAGAWAVSGSPVDCIKLALGDLFLDSLPDIVLSGINNGSNAGRNIFYSGTAGA
ECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHH
AMEAVISGIPAIAFSQEEHISCFQEKKSCELIKMLVLYALSRPFPLLTGFNVNFPACENN
HHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
EEWQGMKLVATGKEFAYGVPRLLCDDGKRKFYSLNDCQRLMDEDLSEECHSLLTKKITVA
CCCCCEEEEECCCHHHHCCCHHHHCCCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLVRNSPLGLMSEEEFQQLQQEFEDFIHSEIRS
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA