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The map label for this gene is dsbG [H]

Identifier: 89898221

GI number: 89898221

Start: 490138

End: 490776

Strand: Direct

Name: dsbG [H]

Synonym: CF0414

Alternate gene names: 89898221

Gene position: 490138-490776 (Clockwise)

Preceding gene: 89898219

Following gene: 89898222

Centisome position: 42.03

GC content: 40.22

Gene sequence:

>639_bases
ATGATATACAAAAAGCAAACGCTATTGCCTCCGAAAGCTCATATCCCTACTAATGCCAAGCATTTTCCAACTCTTGGCAA
TCCTTATGCACCGATTAATATTACAGTTTTTGAAGAGCCCTCTTGTTCTGCATGTGCAGAATTTAGCTCAGAGGTTTTCC
CATTATTAAAGGAGCACTATATTGATACTGGTGAGGTGTCGTTTACATTAATCCCGGTATGCTTTATTCGGGGATCGATG
CCAGCGGCTCAGGCATTGCTTTGTGTATATCATCACGATCCTCGGCAGCCTGATATAGAAGCATATATAGAATATTTCCA
TCGCTTACTTAATTATCCTAAAGAGGAAGGAAAACGTTGGGCAACCCCTGAGGTATTAACTAAGCTTACTGAGAACTTGA
AAACGCATTCTGGCCGCACTATCAATCCTAAGGGATTAATACAGTGTGTAGATTCCCAACAGTATGAAGAGCAAATTAAG
AAGAATAATATTTATGGTTCTCGCGTTCTTGGAGGGCAATTAGCAACTCCGACAGCTGTTGTTGGAGATTATCTTATAGA
AGATCCTACGTTTGATGAATTAGAGCGTGTGATTAAACAAATCCGCCATTTACAAGCTGCAGAGGAAAACGATGATTAG

Upstream 100 bases:

>100_bases
CTCATTTCTGGATGAGTCATATAATAGAAGAGAACGATCATTGAATAAAAAGATACTCGTCATAACTACCAGCATTTTTT
TTGTACTGTGCTTCGGATTA

Downstream 100 bases:

>100_bases
ATTCATTCGTAATTATGCTTTATATTTTGCATGGCTGATTTGTTGTACAGGCACTGTGATGAGTATTTATTACAGTTACC
TATTAAACGTAGAGCCTTGT

Product: disulfide bond chaperone

Products: NA

Alternate protein names: Disulfide oxidoreductase D; Thiol-disulfide oxidoreductase D [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MIYKKQTLLPPKAHIPTNAKHFPTLGNPYAPINITVFEEPSCSACAEFSSEVFPLLKEHYIDTGEVSFTLIPVCFIRGSM
PAAQALLCVYHHDPRQPDIEAYIEYFHRLLNYPKEEGKRWATPEVLTKLTENLKTHSGRTINPKGLIQCVDSQQYEEQIK
KNNIYGSRVLGGQLATPTAVVGDYLIEDPTFDELERVIKQIRHLQAAEENDD

Sequences:

>Translated_212_residues
MIYKKQTLLPPKAHIPTNAKHFPTLGNPYAPINITVFEEPSCSACAEFSSEVFPLLKEHYIDTGEVSFTLIPVCFIRGSM
PAAQALLCVYHHDPRQPDIEAYIEYFHRLLNYPKEEGKRWATPEVLTKLTENLKTHSGRTINPKGLIQCVDSQQYEEQIK
KNNIYGSRVLGGQLATPTAVVGDYLIEDPTFDELERVIKQIRHLQAAEENDD
>Mature_212_residues
MIYKKQTLLPPKAHIPTNAKHFPTLGNPYAPINITVFEEPSCSACAEFSSEVFPLLKEHYIDTGEVSFTLIPVCFIRGSM
PAAQALLCVYHHDPRQPDIEAYIEYFHRLLNYPKEEGKRWATPEVLTKLTENLKTHSGRTINPKGLIQCVDSQQYEEQIK
KNNIYGSRVLGGQLATPTAVVGDYLIEDPTFDELERVIKQIRHLQAAEENDD

Specific function: Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24069; Mature: 24069

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYKKQTLLPPKAHIPTNAKHFPTLGNPYAPINITVFEEPSCSACAEFSSEVFPLLKEHY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHC
IDTGEVSFTLIPVCFIRGSMPAAQALLCVYHHDPRQPDIEAYIEYFHRLLNYPKEEGKRW
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHCCCC
ATPEVLTKLTENLKTHSGRTINPKGLIQCVDSQQYEEQIKKNNIYGSRVLGGQLATPTAV
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHH
VGDYLIEDPTFDELERVIKQIRHLQAAEENDD
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIYKKQTLLPPKAHIPTNAKHFPTLGNPYAPINITVFEEPSCSACAEFSSEVFPLLKEHY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHC
IDTGEVSFTLIPVCFIRGSMPAAQALLCVYHHDPRQPDIEAYIEYFHRLLNYPKEEGKRW
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHCCCC
ATPEVLTKLTENLKTHSGRTINPKGLIQCVDSQQYEEQIKKNNIYGSRVLGGQLATPTAV
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHH
VGDYLIEDPTFDELERVIKQIRHLQAAEENDD
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11844773; 11744713 [H]