Click here to switch to the map view.

The map label for this gene is sucC [H]

Identifier: 89898036

GI number: 89898036

Start: 270848

End: 272014

Strand: Direct

Name: sucC [H]

Synonym: CF0229

Alternate gene names: 89898036

Gene position: 270848-272014 (Clockwise)

Preceding gene: 89898034

Following gene: 89898037

Centisome position: 23.22

GC content: 40.62

Gene sequence:

>1167_bases
ATGCACCTTCATGAATACCAAGCTAAGGATCTTTTGAGCTCTTATGATATTGCCATTCCTCCGTATCGTATAGTCTCTTC
TGTAGAAGAAGGAGAACTGGTTCTTAGGGAGCTGGGTATAAATGCCGGTGTTGTCAAAGTGCAAGTGCACGCTGGAGGAA
GAGGGAAAAATGGTGGCGTAATCATCGCTAAATCTTCTTCTGAAATTCTAGCTGCTATCGGAAAATTATTAAAGATGCGT
TTTGAGAGCAATCAAACTTCAGGAGAATCTCTTCCCGTAGAAAAAGTTCTTATTACACCCCTAGTGAATATTGCTTCTGA
GTATTACCTGGCAGTGATTATGGATAGAAAAAATCGTTGTCCAGCAATTATGTTATCGAAAGCTGGAGGGATGGACATTG
AAGAGGTTGCTCAAAAATATCCTGATCAGTTGCTCACTGTGCCTTTGACTCCTTCTGCTCGTATATACAATTATCAACTC
AGACAGATCATTAAATTTATGAACTGGGAAGGAGATACGGGAAAACAAGGGGTGCAGTTAATTAAAAAGCTTGTCCAATG
CTTCTATGATAACGATGCCTCTTTACTTGAAATCAATCCCTTGGTGCTTACTCAGGAAGAGGAACTCTTAGTATTGGATG
CTAAAGTAACTATTGATGATAACGCCTTATACCGTCACCCCAAACTTGAAGTACTATACGATCCCTCTCAAGAAAATGTT
CGCGATGTACTAGCTAAGAAGATAGGGCTGTCTTACATTGCTCTAGATGGAGACATCGGATGTTTAGTGAATGGCGCAGG
ATTAGCTATGAGTACTCTAGATATTCTTAAAATTCATGGAGGATCTGCTGCAAATTTTCTCGATGTCGGAGGGAGCGCTA
CAGAACAACAGATTCAAGAAGCGGTTTCCTTGGTGCTATCAGATGAAAATGTAGAAGTTCTATTTATTAATATCTTTGGC
GGAATTATGGATTGCTCAGCAGTTGCCTCAGGACTTGTTGCTGTAATGCAAACAAGAGAAAATCTTATTCCTACAGTGGT
GCGTTTAGAGGGAACAAATGTGGAATTGGGAAAAGAAATCGTGCAACGTTCGGGAATCCCCTGCCAATTTACAGATTCCT
TAAATGAAGGCGCACGTCTTGCTGTAGCGCTGAGTAAACAAGTTTAA

Upstream 100 bases:

>100_bases
CTGAATCTTGCTGCTAAAGAACTTAAACACTGATTAGAGCGAAGTTAGTTGAAGTAAAAAGAATGATACAAGATAAAGAG
GAAAATTCAAAGGGTTATTT

Downstream 100 bases:

>100_bases
GGGGCTTTATGTTTTGCTCATTAAGTAAAAAAATACCAATAATTACTCAAGGTATCACAGGAAAAGCAGGATCATTTCAT
ACAGAGAAATGCCTAGAGTA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MHLHEYQAKDLLSSYDIAIPPYRIVSSVEEGELVLRELGINAGVVKVQVHAGGRGKNGGVIIAKSSSEILAAIGKLLKMR
FESNQTSGESLPVEKVLITPLVNIASEYYLAVIMDRKNRCPAIMLSKAGGMDIEEVAQKYPDQLLTVPLTPSARIYNYQL
RQIIKFMNWEGDTGKQGVQLIKKLVQCFYDNDASLLEINPLVLTQEEELLVLDAKVTIDDNALYRHPKLEVLYDPSQENV
RDVLAKKIGLSYIALDGDIGCLVNGAGLAMSTLDILKIHGGSAANFLDVGGSATEQQIQEAVSLVLSDENVEVLFINIFG
GIMDCSAVASGLVAVMQTRENLIPTVVRLEGTNVELGKEIVQRSGIPCQFTDSLNEGARLAVALSKQV

Sequences:

>Translated_388_residues
MHLHEYQAKDLLSSYDIAIPPYRIVSSVEEGELVLRELGINAGVVKVQVHAGGRGKNGGVIIAKSSSEILAAIGKLLKMR
FESNQTSGESLPVEKVLITPLVNIASEYYLAVIMDRKNRCPAIMLSKAGGMDIEEVAQKYPDQLLTVPLTPSARIYNYQL
RQIIKFMNWEGDTGKQGVQLIKKLVQCFYDNDASLLEINPLVLTQEEELLVLDAKVTIDDNALYRHPKLEVLYDPSQENV
RDVLAKKIGLSYIALDGDIGCLVNGAGLAMSTLDILKIHGGSAANFLDVGGSATEQQIQEAVSLVLSDENVEVLFINIFG
GIMDCSAVASGLVAVMQTRENLIPTVVRLEGTNVELGKEIVQRSGIPCQFTDSLNEGARLAVALSKQV
>Mature_388_residues
MHLHEYQAKDLLSSYDIAIPPYRIVSSVEEGELVLRELGINAGVVKVQVHAGGRGKNGGVIIAKSSSEILAAIGKLLKMR
FESNQTSGESLPVEKVLITPLVNIASEYYLAVIMDRKNRCPAIMLSKAGGMDIEEVAQKYPDQLLTVPLTPSARIYNYQL
RQIIKFMNWEGDTGKQGVQLIKKLVQCFYDNDASLLEINPLVLTQEEELLVLDAKVTIDDNALYRHPKLEVLYDPSQENV
RDVLAKKIGLSYIALDGDIGCLVNGAGLAMSTLDILKIHGGSAANFLDVGGSATEQQIQEAVSLVLSDENVEVLFINIFG
GIMDCSAVASGLVAVMQTRENLIPTVVRLEGTNVELGKEIVQRSGIPCQFTDSLNEGARLAVALSKQV

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=395, Percent_Identity=38.9873417721519, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI157779135, Length=374, Percent_Identity=35.5614973262032, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=35.3591160220994, Blast_Score=231, Evalue=1e-60,
Organism=Escherichia coli, GI1786948, Length=383, Percent_Identity=41.5143603133159, Blast_Score=297, Evalue=8e-82,
Organism=Caenorhabditis elegans, GI17539378, Length=392, Percent_Identity=39.5408163265306, Blast_Score=289, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17567829, Length=396, Percent_Identity=37.3737373737374, Blast_Score=269, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=36.6161616161616, Blast_Score=265, Evalue=8e-72,
Organism=Drosophila melanogaster, GI21356231, Length=391, Percent_Identity=40.153452685422, Blast_Score=297, Evalue=7e-81,
Organism=Drosophila melanogaster, GI161078106, Length=395, Percent_Identity=36.9620253164557, Blast_Score=255, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24645208, Length=395, Percent_Identity=36.9620253164557, Blast_Score=255, Evalue=3e-68,
Organism=Drosophila melanogaster, GI281361397, Length=396, Percent_Identity=36.8686868686869, Blast_Score=251, Evalue=7e-67,
Organism=Drosophila melanogaster, GI281361395, Length=396, Percent_Identity=36.8686868686869, Blast_Score=251, Evalue=7e-67,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42208; Mature: 42208

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLHEYQAKDLLSSYDIAIPPYRIVSSVEEGELVLRELGINAGVVKVQVHAGGRGKNGGV
CCCCHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCE
IIAKSSSEILAAIGKLLKMRFESNQTSGESLPVEKVLITPLVNIASEYYLAVIMDRKNRC
EEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCC
PAIMLSKAGGMDIEEVAQKYPDQLLTVPLTPSARIYNYQLRQIIKFMNWEGDTGKQGVQL
CEEEEECCCCCCHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHH
IKKLVQCFYDNDASLLEINPLVLTQEEELLVLDAKVTIDDNALYRHPKLEVLYDPSQENV
HHHHHHHHHCCCCCEEEECCEEEECCCCEEEEEEEEEECCCCEEECCCEEEEECCCHHHH
RDVLAKKIGLSYIALDGDIGCLVNGAGLAMSTLDILKIHGGSAANFLDVGGSATEQQIQE
HHHHHHHHCCEEEEECCCCEEEEECCCHHHHHEEEEEECCCCCCCEEECCCCCHHHHHHH
AVSLVLSDENVEVLFINIFGGIMDCSAVASGLVAVMQTRENLIPTVVRLEGTNVELGKEI
HHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
VQRSGIPCQFTDSLNEGARLAVALSKQV
HHHCCCCEEECCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MHLHEYQAKDLLSSYDIAIPPYRIVSSVEEGELVLRELGINAGVVKVQVHAGGRGKNGGV
CCCCHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCE
IIAKSSSEILAAIGKLLKMRFESNQTSGESLPVEKVLITPLVNIASEYYLAVIMDRKNRC
EEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCC
PAIMLSKAGGMDIEEVAQKYPDQLLTVPLTPSARIYNYQLRQIIKFMNWEGDTGKQGVQL
CEEEEECCCCCCHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHH
IKKLVQCFYDNDASLLEINPLVLTQEEELLVLDAKVTIDDNALYRHPKLEVLYDPSQENV
HHHHHHHHHCCCCCEEEECCEEEECCCCEEEEEEEEEECCCCEEECCCEEEEECCCHHHH
RDVLAKKIGLSYIALDGDIGCLVNGAGLAMSTLDILKIHGGSAANFLDVGGSATEQQIQE
HHHHHHHHCCEEEEECCCCEEEEECCCHHHHHEEEEEECCCCCCCEEECCCCCHHHHHHH
AVSLVLSDENVEVLFINIFGGIMDCSAVASGLVAVMQTRENLIPTVVRLEGTNVELGKEI
HHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
VQRSGIPCQFTDSLNEGARLAVALSKQV
HHHCCCCEEECCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]