Click here to switch to the map view.

The map label for this gene is gdhA [H]

Identifier: 89897973

GI number: 89897973

Start: 196922

End: 197971

Strand: Direct

Name: gdhA [H]

Synonym: CF0166

Alternate gene names: 89897973

Gene position: 196922-197971 (Clockwise)

Preceding gene: 89897971

Following gene: 89897975

Centisome position: 16.89

GC content: 42.48

Gene sequence:

>1050_bases
ATGAAGTATCCCTTAGTGTTCAAAGATGTAAATATCAAAGATTACGAACGCGTAATTGAAGTCACGTGTGAAAGTATTCA
ATTACATGCGTTGATTGCTATTCATCAAACACTAGTAGGACCCGCATTAGGTGGAGTTCGTGCTTTTGCTTACGCTTCTT
TTGACGATGCCCTAACAGATGTTTTACGTTTGTCAAGAGGCATGACCTATAAAGCTATTCTCAGCGATACAGGAACCGGA
GGCGGGAAAAGCGTGATTATTCTTCCTAAGGGTATGACACGTCCAACTGAAGATATGCTGCGGGCTTTTGGCCAGGCCGT
TGATTCTCTAGGTGGGCAGTATATTGCCGCTGAAGACATGGGAGTTTCTGTTAATGATATTAATACTATTTATCAAGAGA
CGCAGTGGGTATGCGGTATAGAGAGTGTAAGCGGTGATCCTTCAATTTACACCGCGCACGGTGTCTTTTTATGCATAAAA
GAGACTGCGGAGCAATTGTGGGGGGATTCTTCCTTGAAGGGAAGAAAAATAGGTATTCAAGGTCTTGGTTCTGTTGGGAG
AAAGTTACTGCTCTCTCTATTTTTCGAAGGTGCCGACCTCTTTGTCTGTGATACCAATCAAGCTATCCTTGATGAAGTTA
CCAAGTTTTATGGCGTAACTGTTGTTGCTAAAGATGCTTTCCCAACGTTAGAATGCGATATTTTTGTCCCATGTGCCTTT
GGTGGGGTGATTAATAAAAGTAATGTCTACAACTTACGCTGTCGTGCCATCGTAGGAGCTGCGAATAACCAGTTAGAAAA
CGCCTCTTTAGGCGCTGTGCTGCAAGCTCAGGGAATATTATATGCCCCAGACTACTTGGCTAATGCTGGGGGGTTATTGA
ATGTAGCTCTTGCTGTTGGAAAGACTTATTGTCCAAAAACAGTCTTGCAAAAAGTCAGTAAGCTTCCTGAGATTCTTAGA
GAAATTTACGAGAAAAGCGAAACTTCCACTCAGGATACGGTAACCCTCTCCGATAGGATGGTAGAAGAAAAACTTGCAGC
TTATATTTAA

Upstream 100 bases:

>100_bases
GAGGAATTTTAAGAGAAGGGAGAGGGGTGGTTAATTGACTTTTAATTAAATCTATACAATACTCGCGCATTATAATTACA
AATCCGCCTAATTTAAGATT

Downstream 100 bases:

>100_bases
TAAGTTAGTAGGTTTCCTGCAGGAATAATATTCAATTGTTCTTGTAGCGTTTCTAAAGTGATTTTATGAATCTCTTCATT
CCCAGATGCTAAAATTATGG

Product: glutamate/leucine dehydrogenase

Products: NA

Alternate protein names: LeuDH [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MKYPLVFKDVNIKDYERVIEVTCESIQLHALIAIHQTLVGPALGGVRAFAYASFDDALTDVLRLSRGMTYKAILSDTGTG
GGKSVIILPKGMTRPTEDMLRAFGQAVDSLGGQYIAAEDMGVSVNDINTIYQETQWVCGIESVSGDPSIYTAHGVFLCIK
ETAEQLWGDSSLKGRKIGIQGLGSVGRKLLLSLFFEGADLFVCDTNQAILDEVTKFYGVTVVAKDAFPTLECDIFVPCAF
GGVINKSNVYNLRCRAIVGAANNQLENASLGAVLQAQGILYAPDYLANAGGLLNVALAVGKTYCPKTVLQKVSKLPEILR
EIYEKSETSTQDTVTLSDRMVEEKLAAYI

Sequences:

>Translated_349_residues
MKYPLVFKDVNIKDYERVIEVTCESIQLHALIAIHQTLVGPALGGVRAFAYASFDDALTDVLRLSRGMTYKAILSDTGTG
GGKSVIILPKGMTRPTEDMLRAFGQAVDSLGGQYIAAEDMGVSVNDINTIYQETQWVCGIESVSGDPSIYTAHGVFLCIK
ETAEQLWGDSSLKGRKIGIQGLGSVGRKLLLSLFFEGADLFVCDTNQAILDEVTKFYGVTVVAKDAFPTLECDIFVPCAF
GGVINKSNVYNLRCRAIVGAANNQLENASLGAVLQAQGILYAPDYLANAGGLLNVALAVGKTYCPKTVLQKVSKLPEILR
EIYEKSETSTQDTVTLSDRMVEEKLAAYI
>Mature_349_residues
MKYPLVFKDVNIKDYERVIEVTCESIQLHALIAIHQTLVGPALGGVRAFAYASFDDALTDVLRLSRGMTYKAILSDTGTG
GGKSVIILPKGMTRPTEDMLRAFGQAVDSLGGQYIAAEDMGVSVNDINTIYQETQWVCGIESVSGDPSIYTAHGVFLCIK
ETAEQLWGDSSLKGRKIGIQGLGSVGRKLLLSLFFEGADLFVCDTNQAILDEVTKFYGVTVVAKDAFPTLECDIFVPCAF
GGVINKSNVYNLRCRAIVGAANNQLENASLGAVLQAQGILYAPDYLANAGGLLNVALAVGKTYCPKTVLQKVSKLPEILR
EIYEKSETSTQDTVTLSDRMVEEKLAAYI

Specific function: Functions catabolically in the bacterial metabolism of branched-chain L-amino acids, and plays an important role in spore germination in cooperation with alanine dehydrogenase [H]

COG id: COG0334

COG function: function code E; Glutamate dehydrogenase/leucine dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006095
- InterPro:   IPR006096
- InterPro:   IPR006097
- InterPro:   IPR016211
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00208 ELFV_dehydrog; PF02812 ELFV_dehydrog_N [H]

EC number: =1.4.1.9 [H]

Molecular weight: Translated: 37706; Mature: 37706

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYPLVFKDVNIKDYERVIEVTCESIQLHALIAIHQTLVGPALGGVRAFAYASFDDALTD
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
VLRLSRGMTYKAILSDTGTGGGKSVIILPKGMTRPTEDMLRAFGQAVDSLGGQYIAAEDM
HHHHHCCCEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCC
GVSVNDINTIYQETQWVCGIESVSGDPSIYTAHGVFLCIKETAEQLWGDSSLKGRKIGIQ
CCCHHHHHHHHHHHHHEEEECCCCCCCCEEEECCEEEEHHHHHHHHCCCCCCCCCEECHH
GLGSVGRKLLLSLFFEGADLFVCDTNQAILDEVTKFYGVTVVAKDAFPTLECDIFVPCAF
HHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCEEEEEECCCCCEEEEEEEEECC
GGVINKSNVYNLRCRAIVGAANNQLENASLGAVLQAQGILYAPDYLANAGGLLNVALAVG
CCEECCCCEEEEEEEEEEECCCCCCCCCHHCHHEEECCCEECCHHHHCCCCHHHHHHHHC
KTYCPKTVLQKVSKLPEILREIYEKSETSTQDTVTLSDRMVEEKLAAYI
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MKYPLVFKDVNIKDYERVIEVTCESIQLHALIAIHQTLVGPALGGVRAFAYASFDDALTD
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
VLRLSRGMTYKAILSDTGTGGGKSVIILPKGMTRPTEDMLRAFGQAVDSLGGQYIAAEDM
HHHHHCCCEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCC
GVSVNDINTIYQETQWVCGIESVSGDPSIYTAHGVFLCIKETAEQLWGDSSLKGRKIGIQ
CCCHHHHHHHHHHHHHEEEECCCCCCCCEEEECCEEEEHHHHHHHHCCCCCCCCCEECHH
GLGSVGRKLLLSLFFEGADLFVCDTNQAILDEVTKFYGVTVVAKDAFPTLECDIFVPCAF
HHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCEEEEEECCCCCEEEEEEEEECC
GGVINKSNVYNLRCRAIVGAANNQLENASLGAVLQAQGILYAPDYLANAGGLLNVALAVG
CCEECCCCEEEEEEEEEEECCCCCCCCCHHCHHEEECCCEECCHHHHCCCCHHHHHHHHC
KTYCPKTVLQKVSKLPEILREIYEKSETSTQDTVTLSDRMVEEKLAAYI
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3069133; 1400267 [H]