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The map label for this gene is tkt [H]

Identifier: 89897948

GI number: 89897948

Start: 171152

End: 173149

Strand: Direct

Name: tkt [H]

Synonym: CF0141

Alternate gene names: 89897948

Gene position: 171152-173149 (Clockwise)

Preceding gene: 89897942

Following gene: 89897950

Centisome position: 14.68

GC content: 42.04

Gene sequence:

>1998_bases
ATGGTGAACAGAGAAGTAGATGTAGATATCTTAGAAAAGATCTCAGGAACTCTTAAACAGTTGAGTATAGAGATCATTCA
AAAAGCTGGTTCTGGTCATCCTGGATTGCCTTTAGGGTGCGCAGAACTTGCGGCTTATTTGTATAGTTATGTTTTGAAAC
ACAATCCTAAAGATCCTTTGTGGATTGCTAGAGATCGTTTCGTTTTGTCTGCAGGACACGGTTCGGCTTTGCTGTATTCA
TGTCTGCATCTTGCTGGATACGACGTCTCTTTGGAAGATCTTCAGCAATTTCGTCAGTTACATTCACGTACTCCTGGTCA
TCCGGAATTTGGAGAGACTGAGGGAGTTGAAGCGACTACAGGCCCTCTAGGTCAGGGGCTGGGCAATGCAGTGGGTATGG
CCCTGTCTATGAAGATGCTTGGAGTTCGTTTCAATCGACCAGATCATGAAATTTTTAATAGCAAAGTATACTGTTTGGCT
GGTGACGGATGCATGATGGAAGGCGTTAGCCATGAAGTTTGTAGTCTGGCTGGGACTTTAGAATTAGATAATCTTGTAGT
TATATATGATTACAATCATATTGTATTAGATGGCTTCCTGGGAGAGGTTTGTTTAGAAGATGTTAAAAAGCGTTTTGAGG
CTTATGGCTGGGAAGTGTATGAAATCGATGGGTATGATTTCTCTGCTATTCATGAAACATTTGTAAACATTAAACAACAC
CAGAAACGTCCGGCATTAATTGTTGCGCATACAATTATAGGCCACGGTTCTCCTAAAGAAGGTAGCCATAAAGCTCATGG
TTCTCCCTTAGGGGAAGCCGGAGTAGAACAAACAAAACATTTCTGGCGTCTGCCTGAGGAGAAATTTTTCATTTCTCCTG
TAGTAAAGTCTTTCTTCTCCAATAAATTACAAGAAGATCGTAAGATTCAGGAAGAATGGCAAGACGATTTTCGTGTTTGG
TCACGTCAGTTTCCTGAATTACATAAAGAATTTCTTTCATTGAAGGCTCCAATATCCTCAGAAACATTAGAGACGATATT
TGAGAATATAGAAATGCCGGAGGTTATAGCAGGACGTGCTGCATCTAACAAAATAATTCAAGATTTAGCTAAACATATCC
CTTCGCTTGTAGGAGGGTCGGCAGATTTATCTAGTTCCGATGGGACTTGGATATCAGACGCTAAGGATATTAATAGCCAC
GATTTTTCTGGTAGAAATATTAAATACGGCGTGCGGGAATTTGGTATGGGGACCGTTATGAATGGTCTTGCTTACTCTCA
AGTATTCCGACCTTTTGGAGGCACATTCTTGGTGTTTTCTGATTATCTAAGAAATGCCATCCGTTTAGCAGCATTGGCTA
AGTTGCCTGTCATTTACCAATTTACGCACGATTCTATTTTTGTTGGTGAGGATGGCCCTACACACCAACCTATTGAGCAA
ATCATGTCGTTAAGAGCTATTCCAGGTTTACAAGTTATCCGCCCCGGAGATGCTAATGAAGTGAAGGGAGCTTGGCATGC
GGCGTTACGTTATCCCGGTCCAACAGCATTGATTCTGTCTCGACAAAATTTACCCACGCTGTCACAAACCAATAGACCGT
TTAAAGAAGGTGTGGGACGTGGAGCCTATATTGTTTTAAAGGAAGCTCAAGGGAAGATAGATTATACCTTATTTGCTACA
GGATCGGAATTGCACTTAGCTTTGGCTGTTGCGCAAGAGTTGATCTACTTAGATAAAAAAGTGCGTGTAGTTTCCTTCCC
GTGCTGGGAATTGTTCGAACAACAAGATTTCGAATATCGAGAAAGTGTTGTCGGCGGTGACTTAGGTTTGCGAGTATCTA
TAGAAGCGGGGTCTGCTTTGGGGTGGTATAAATATATAGGTTCCAACGGTTTGGCCATTGCTATGGATAGGTTTGGTTAC
TCGGGAGCTCCCGCTGATGTTGCAGAAGCTTGTGGGTTCACCGCAGATTGCATTTTACAGAGAATACTTTCTCAGTAG

Upstream 100 bases:

>100_bases
GGTGAAATCTTATATGCATTGAGTAATCTTGCTTTTTGGTAAAGCATGTCCTATAATTTTGATCTTTGTATTCTTTATGA
AGCGCTTTTAGGTCTGGCAA

Downstream 100 bases:

>100_bases
TCATTGTCGGAAAAACCGAAATCTTTAGGCATAGCGTCATCGGCTTCGCCAAGCTCCATGTGAGGCAAGCCTTTGTTAGC
TTTTATAGGCAGGTTTTTCA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MVNREVDVDILEKISGTLKQLSIEIIQKAGSGHPGLPLGCAELAAYLYSYVLKHNPKDPLWIARDRFVLSAGHGSALLYS
CLHLAGYDVSLEDLQQFRQLHSRTPGHPEFGETEGVEATTGPLGQGLGNAVGMALSMKMLGVRFNRPDHEIFNSKVYCLA
GDGCMMEGVSHEVCSLAGTLELDNLVVIYDYNHIVLDGFLGEVCLEDVKKRFEAYGWEVYEIDGYDFSAIHETFVNIKQH
QKRPALIVAHTIIGHGSPKEGSHKAHGSPLGEAGVEQTKHFWRLPEEKFFISPVVKSFFSNKLQEDRKIQEEWQDDFRVW
SRQFPELHKEFLSLKAPISSETLETIFENIEMPEVIAGRAASNKIIQDLAKHIPSLVGGSADLSSSDGTWISDAKDINSH
DFSGRNIKYGVREFGMGTVMNGLAYSQVFRPFGGTFLVFSDYLRNAIRLAALAKLPVIYQFTHDSIFVGEDGPTHQPIEQ
IMSLRAIPGLQVIRPGDANEVKGAWHAALRYPGPTALILSRQNLPTLSQTNRPFKEGVGRGAYIVLKEAQGKIDYTLFAT
GSELHLALAVAQELIYLDKKVRVVSFPCWELFEQQDFEYRESVVGGDLGLRVSIEAGSALGWYKYIGSNGLAIAMDRFGY
SGAPADVAEACGFTADCILQRILSQ

Sequences:

>Translated_665_residues
MVNREVDVDILEKISGTLKQLSIEIIQKAGSGHPGLPLGCAELAAYLYSYVLKHNPKDPLWIARDRFVLSAGHGSALLYS
CLHLAGYDVSLEDLQQFRQLHSRTPGHPEFGETEGVEATTGPLGQGLGNAVGMALSMKMLGVRFNRPDHEIFNSKVYCLA
GDGCMMEGVSHEVCSLAGTLELDNLVVIYDYNHIVLDGFLGEVCLEDVKKRFEAYGWEVYEIDGYDFSAIHETFVNIKQH
QKRPALIVAHTIIGHGSPKEGSHKAHGSPLGEAGVEQTKHFWRLPEEKFFISPVVKSFFSNKLQEDRKIQEEWQDDFRVW
SRQFPELHKEFLSLKAPISSETLETIFENIEMPEVIAGRAASNKIIQDLAKHIPSLVGGSADLSSSDGTWISDAKDINSH
DFSGRNIKYGVREFGMGTVMNGLAYSQVFRPFGGTFLVFSDYLRNAIRLAALAKLPVIYQFTHDSIFVGEDGPTHQPIEQ
IMSLRAIPGLQVIRPGDANEVKGAWHAALRYPGPTALILSRQNLPTLSQTNRPFKEGVGRGAYIVLKEAQGKIDYTLFAT
GSELHLALAVAQELIYLDKKVRVVSFPCWELFEQQDFEYRESVVGGDLGLRVSIEAGSALGWYKYIGSNGLAIAMDRFGY
SGAPADVAEACGFTADCILQRILSQ
>Mature_665_residues
MVNREVDVDILEKISGTLKQLSIEIIQKAGSGHPGLPLGCAELAAYLYSYVLKHNPKDPLWIARDRFVLSAGHGSALLYS
CLHLAGYDVSLEDLQQFRQLHSRTPGHPEFGETEGVEATTGPLGQGLGNAVGMALSMKMLGVRFNRPDHEIFNSKVYCLA
GDGCMMEGVSHEVCSLAGTLELDNLVVIYDYNHIVLDGFLGEVCLEDVKKRFEAYGWEVYEIDGYDFSAIHETFVNIKQH
QKRPALIVAHTIIGHGSPKEGSHKAHGSPLGEAGVEQTKHFWRLPEEKFFISPVVKSFFSNKLQEDRKIQEEWQDDFRVW
SRQFPELHKEFLSLKAPISSETLETIFENIEMPEVIAGRAASNKIIQDLAKHIPSLVGGSADLSSSDGTWISDAKDINSH
DFSGRNIKYGVREFGMGTVMNGLAYSQVFRPFGGTFLVFSDYLRNAIRLAALAKLPVIYQFTHDSIFVGEDGPTHQPIEQ
IMSLRAIPGLQVIRPGDANEVKGAWHAALRYPGPTALILSRQNLPTLSQTNRPFKEGVGRGAYIVLKEAQGKIDYTLFAT
GSELHLALAVAQELIYLDKKVRVVSFPCWELFEQQDFEYRESVVGGDLGLRVSIEAGSALGWYKYIGSNGLAIAMDRFGY
SGAPADVAEACGFTADCILQRILSQ

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=677, Percent_Identity=26.5878877400295, Blast_Score=182, Evalue=9e-46,
Organism=Homo sapiens, GI4507521, Length=677, Percent_Identity=26.5878877400295, Blast_Score=182, Evalue=9e-46,
Organism=Homo sapiens, GI133778974, Length=584, Percent_Identity=27.2260273972603, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI225637459, Length=583, Percent_Identity=24.8713550600343, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI225637463, Length=500, Percent_Identity=25.6, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI225637461, Length=500, Percent_Identity=25.6, Blast_Score=129, Evalue=7e-30,
Organism=Escherichia coli, GI1788808, Length=661, Percent_Identity=46.2934947049924, Blast_Score=555, Evalue=1e-159,
Organism=Escherichia coli, GI48994911, Length=659, Percent_Identity=45.0682852807284, Blast_Score=553, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI17539652, Length=567, Percent_Identity=27.8659611992945, Blast_Score=167, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6325331, Length=668, Percent_Identity=42.3652694610778, Blast_Score=496, Evalue=1e-141,
Organism=Saccharomyces cerevisiae, GI6319593, Length=669, Percent_Identity=41.2556053811659, Blast_Score=469, Evalue=1e-133,
Organism=Drosophila melanogaster, GI45551847, Length=582, Percent_Identity=26.8041237113402, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI45550715, Length=582, Percent_Identity=26.8041237113402, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24666278, Length=579, Percent_Identity=25.0431778929188, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24645119, Length=538, Percent_Identity=26.9516728624535, Blast_Score=151, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 73589; Mature: 73589

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNREVDVDILEKISGTLKQLSIEIIQKAGSGHPGLPLGCAELAAYLYSYVLKHNPKDPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCE
WIARDRFVLSAGHGSALLYSCLHLAGYDVSLEDLQQFRQLHSRTPGHPEFGETEGVEATT
EEEECCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GPLGQGLGNAVGMALSMKMLGVRFNRPDHEIFNSKVYCLAGDGCMMEGVSHEVCSLAGTL
CCHHHHHHHHHHHHHHHHHHHEECCCCCHHHHCCEEEEEECCCHHHCCCCHHHHHHHCCE
ELDNLVVIYDYNHIVLDGFLGEVCLEDVKKRFEAYGWEVYEIDGYDFSAIHETFVNIKQH
EECCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHH
QKRPALIVAHTIIGHGSPKEGSHKAHGSPLGEAGVEQTKHFWRLPEEKFFISPVVKSFFS
CCCCEEEEEEEHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
NKLQEDRKIQEEWQDDFRVWSRQFPELHKEFLSLKAPISSETLETIFENIEMPEVIAGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHCCC
ASNKIIQDLAKHIPSLVGGSADLSSSDGTWISDAKDINSHDFSGRNIKYGVREFGMGTVM
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHCHHHHH
NGLAYSQVFRPFGGTFLVFSDYLRNAIRLAALAKLPVIYQFTHDSIFVGEDGPTHQPIEQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCHHHHHH
IMSLRAIPGLQVIRPGDANEVKGAWHAALRYPGPTALILSRQNLPTLSQTNRPFKEGVGR
HHHHHCCCCCEEECCCCCCCCCHHHHHHEECCCCEEEEEECCCCCCHHHCCCCHHHCCCC
GAYIVLKEAQGKIDYTLFATGSELHLALAVAQELIYLDKKVRVVSFPCWELFEQQDFEYR
CEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCHHHH
ESVVGGDLGLRVSIEAGSALGWYKYIGSNGLAIAMDRFGYSGAPADVAEACGFTADCILQ
HHHCCCCCCEEEEEECCCCCHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCCCHHHHHH
RILSQ
HHHCC
>Mature Secondary Structure
MVNREVDVDILEKISGTLKQLSIEIIQKAGSGHPGLPLGCAELAAYLYSYVLKHNPKDPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCE
WIARDRFVLSAGHGSALLYSCLHLAGYDVSLEDLQQFRQLHSRTPGHPEFGETEGVEATT
EEEECCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GPLGQGLGNAVGMALSMKMLGVRFNRPDHEIFNSKVYCLAGDGCMMEGVSHEVCSLAGTL
CCHHHHHHHHHHHHHHHHHHHEECCCCCHHHHCCEEEEEECCCHHHCCCCHHHHHHHCCE
ELDNLVVIYDYNHIVLDGFLGEVCLEDVKKRFEAYGWEVYEIDGYDFSAIHETFVNIKQH
EECCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHH
QKRPALIVAHTIIGHGSPKEGSHKAHGSPLGEAGVEQTKHFWRLPEEKFFISPVVKSFFS
CCCCEEEEEEEHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
NKLQEDRKIQEEWQDDFRVWSRQFPELHKEFLSLKAPISSETLETIFENIEMPEVIAGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHCCC
ASNKIIQDLAKHIPSLVGGSADLSSSDGTWISDAKDINSHDFSGRNIKYGVREFGMGTVM
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHCHHHHH
NGLAYSQVFRPFGGTFLVFSDYLRNAIRLAALAKLPVIYQFTHDSIFVGEDGPTHQPIEQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCHHHHHH
IMSLRAIPGLQVIRPGDANEVKGAWHAALRYPGPTALILSRQNLPTLSQTNRPFKEGVGR
HHHHHCCCCCEEECCCCCCCCCHHHHHHEECCCCEEEEEECCCCCCHHHCCCCHHHCCCC
GAYIVLKEAQGKIDYTLFATGSELHLALAVAQELIYLDKKVRVVSFPCWELFEQQDFEYR
CEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCHHHH
ESVVGGDLGLRVSIEAGSALGWYKYIGSNGLAIAMDRFGYSGAPADVAEACGFTADCILQ
HHHCCCCCCEEEEEECCCCCHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCCCHHHHHH
RILSQ
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]