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The map label for this gene is ung [H]

Identifier: 89897836

GI number: 89897836

Start: 30303

End: 30992

Strand: Direct

Name: ung [H]

Synonym: CF0029

Alternate gene names: 89897836

Gene position: 30303-30992 (Clockwise)

Preceding gene: 89897833

Following gene: 89897837

Centisome position: 2.6

GC content: 41.88

Gene sequence:

>690_bases
ATGCAAAACGCCTTTACTATAGACCAGCTTCCTTTGTCTTGGCAAGAGCAGCTTGAAAATGAATGGTCTCAGCCTTACAT
GCATAAGCTTAGGGAATTTTTACAAACCGAGTATTCTCGGACAACAGTTTATCCCGCAAAAGACAATATCTTTACTGCAT
TAAAAAGCACACCTTTTGATGCTGTGCGTGTTGTTGTTCTCGGTCAGGATCCCTATCCTGGAGAAGGACAAGCTCACGGA
CTAAGCTTTAGCGTGCCTCATGGTGTACGCTTACCCCCATCTCTAATGAATATTTTTCGTGAATTGCAAACAGATTTAGG
AATAAAAAATACGACGGGATGTTTGCAGCCTTGGGCAGATCAAGGTGTCTTATTATTAAATACTGTATTGACTGTACGTG
CGGGAGCTCCTTTTTCTCATGCTGGTCAAGGATGGGAGCGGTTTACCGATGCTATTGTTACCAAACTTATAGAAAATCGA
TCACACGTGATTTTTGTCTTATGGGGGAATGCTGCAAGAAAAAAATGTGACTTACTGTTCCGTTCTACTCATAAACATGC
CATTTTAGCAGCTGCTCATCCTTCTCCTTTAGCAGCGCACCGCGGCTTTTTTGGTTGTTCTCACTTTTCAAAAATTAACT
ACCTGCTTAAAAAGCTGGAAAGGCCCATGATTAATTGGAAGCTCCCATGA

Upstream 100 bases:

>100_bases
ATTTATAGCTTCCGACTGAAAAAAATCAGGATCCCCGAAGCTAAAATAATCTAAGAAGGTTAATATACTTCTATTTTCAA
ACAATAAAAGTGGGTGGTTT

Downstream 100 bases:

>100_bases
GTGAAAGTATTCAAACTGTTTCTTTTAATAAAACTCACCGACTTACAGCGAAATCTACAGTGAGTTTAGAAATGCCCGTA
GCAACGCAGAAGCTTCAAGG

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MQNAFTIDQLPLSWQEQLENEWSQPYMHKLREFLQTEYSRTTVYPAKDNIFTALKSTPFDAVRVVVLGQDPYPGEGQAHG
LSFSVPHGVRLPPSLMNIFRELQTDLGIKNTTGCLQPWADQGVLLLNTVLTVRAGAPFSHAGQGWERFTDAIVTKLIENR
SHVIFVLWGNAARKKCDLLFRSTHKHAILAAAHPSPLAAHRGFFGCSHFSKINYLLKKLERPMINWKLP

Sequences:

>Translated_229_residues
MQNAFTIDQLPLSWQEQLENEWSQPYMHKLREFLQTEYSRTTVYPAKDNIFTALKSTPFDAVRVVVLGQDPYPGEGQAHG
LSFSVPHGVRLPPSLMNIFRELQTDLGIKNTTGCLQPWADQGVLLLNTVLTVRAGAPFSHAGQGWERFTDAIVTKLIENR
SHVIFVLWGNAARKKCDLLFRSTHKHAILAAAHPSPLAAHRGFFGCSHFSKINYLLKKLERPMINWKLP
>Mature_229_residues
MQNAFTIDQLPLSWQEQLENEWSQPYMHKLREFLQTEYSRTTVYPAKDNIFTALKSTPFDAVRVVVLGQDPYPGEGQAHG
LSFSVPHGVRLPPSLMNIFRELQTDLGIKNTTGCLQPWADQGVLLLNTVLTVRAGAPFSHAGQGWERFTDAIVTKLIENR
SHVIFVLWGNAARKKCDLLFRSTHKHAILAAAHPSPLAAHRGFFGCSHFSKINYLLKKLERPMINWKLP

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=217, Percent_Identity=49.3087557603687, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI6224979, Length=217, Percent_Identity=49.3087557603687, Blast_Score=201, Evalue=3e-52,
Organism=Escherichia coli, GI1788934, Length=218, Percent_Identity=46.3302752293578, Blast_Score=201, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17556304, Length=219, Percent_Identity=45.662100456621, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6323620, Length=239, Percent_Identity=43.0962343096234, Blast_Score=180, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 25931; Mature: 25931

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNAFTIDQLPLSWQEQLENEWSQPYMHKLREFLQTEYSRTTVYPAKDNIFTALKSTPFD
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHCCCCC
AVRVVVLGQDPYPGEGQAHGLSFSVPHGVRLPPSLMNIFRELQTDLGIKNTTGCLQPWAD
CEEEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
QGVLLLNTVLTVRAGAPFSHAGQGWERFTDAIVTKLIENRSHVIFVLWGNAARKKCDLLF
CCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
RSTHKHAILAAAHPSPLAAHRGFFGCSHFSKINYLLKKLERPMINWKLP
HCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQNAFTIDQLPLSWQEQLENEWSQPYMHKLREFLQTEYSRTTVYPAKDNIFTALKSTPFD
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHCCCCC
AVRVVVLGQDPYPGEGQAHGLSFSVPHGVRLPPSLMNIFRELQTDLGIKNTTGCLQPWAD
CEEEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
QGVLLLNTVLTVRAGAPFSHAGQGWERFTDAIVTKLIENRSHVIFVLWGNAARKKCDLLF
CCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
RSTHKHAILAAAHPSPLAAHRGFFGCSHFSKINYLLKKLERPMINWKLP
HCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA