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The map label for this gene is oxr3 [H]

Identifier: 89897831

GI number: 89897831

Start: 21969

End: 22988

Strand: Direct

Name: oxr3 [H]

Synonym: CF0024

Alternate gene names: 89897831

Gene position: 21969-22988 (Clockwise)

Preceding gene: 89897830

Following gene: 89897833

Centisome position: 1.88

GC content: 42.94

Gene sequence:

>1020_bases
ATGGCTTCTTCAATACATATAGGAAATATTTTACTAAAATCCCCTATTGTTTACGCACCCCTAGCGGGTTTTTCAGATTA
TCCCTATCGGAGAATGTCTTCGCTTTACGGTCTTCCAGCTTTAATGTTTTGTGAGATGGTGAAGATCGAGGGCTTGCACT
ATTCTCCTTCGCGTACCCTCAAACTTCTAGAATATTCTGAATCCATGCGTCCTATAGGAGGACAGCTTTGTGGTAGCAAA
CCTGAGATGGCTGGAGAAGCCGCTAAGGTATTAGAAGGATTGGGTTTTGATTTAATAGACTTAAACTGCGGTTGCCCTAC
AGATAGAATTACTAAAGATGGTAGTGGGTCAGGCCTATTAAAGACTCCAGAGCTTATTGGAAAAGTTTTGGAAAAGATTA
TCGGGTCTGTATCCATTCCTGTTACTGTAAAAATACGTTCAGGGTGGGACGGAAATAACATTAATGTGGAAGAAACAGTG
CGCATTATTAAAGAGGCGGGAGCGAGTGCTGTTTTTGTACATGGAAGGACTCGTGCTCAGGGATATGTTGGTCCTAGTAA
TCTTGAATACATAGCACGAGCAAAAGCCGCGGCGGGGAAGGATTTTCCTGTATTTGGCAATGGGGATGTGTTTTCTCCAG
AAGCCGCTAAGCTAATGTTAGACTCTACGGGATGTGATGGAGTCCTTGTTGCTCGTGGTACTATGGGGGCCCCTTGGATA
GCGCGCCAAATTGAAGATTATCTTACGACAGGGACGTATCAGAAAATGCCCTTCTCTACGAGAAAACAAGCTTTTCTCCA
GCACTTACATTGGGTAGAGGAGTACTATCAAAGTGAAGCAAAGTTTCTTTGTGAAACAAGAAAACTTTGCGGACATTATC
TCATATCCGCTGCTAAAGTAAGATTTCTTCGTTCAGCTTTATCTAAAGCTACGTCTGTGCAAGCAGTTTATCAGCTTATC
GAGGCTTATGAAGAATCCGATGATGAGCCTAGGGATCAACCAGACTTAAACAAGTGCTGA

Upstream 100 bases:

>100_bases
TCGATATTAGCCCTTTGATTGCTCTACTTTGCTTAGAGGCTGTTCCTTTTATTGTGATACGAACCCTGAGGTTTGTTATT
CTTAATATTTTTCAGTCTCC

Downstream 100 bases:

>100_bases
TTTAGTAGTTTGGGCAGTTGGAACATATCCACGGGTTCTGGGCCAATAACCCCTCGGAATTTATCGTCAGGAATTAACAT
CTTTTTATTTTCGGGGGACT

Product: dehydrogenases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MASSIHIGNILLKSPIVYAPLAGFSDYPYRRMSSLYGLPALMFCEMVKIEGLHYSPSRTLKLLEYSESMRPIGGQLCGSK
PEMAGEAAKVLEGLGFDLIDLNCGCPTDRITKDGSGSGLLKTPELIGKVLEKIIGSVSIPVTVKIRSGWDGNNINVEETV
RIIKEAGASAVFVHGRTRAQGYVGPSNLEYIARAKAAAGKDFPVFGNGDVFSPEAAKLMLDSTGCDGVLVARGTMGAPWI
ARQIEDYLTTGTYQKMPFSTRKQAFLQHLHWVEEYYQSEAKFLCETRKLCGHYLISAAKVRFLRSALSKATSVQAVYQLI
EAYEESDDEPRDQPDLNKC

Sequences:

>Translated_339_residues
MASSIHIGNILLKSPIVYAPLAGFSDYPYRRMSSLYGLPALMFCEMVKIEGLHYSPSRTLKLLEYSESMRPIGGQLCGSK
PEMAGEAAKVLEGLGFDLIDLNCGCPTDRITKDGSGSGLLKTPELIGKVLEKIIGSVSIPVTVKIRSGWDGNNINVEETV
RIIKEAGASAVFVHGRTRAQGYVGPSNLEYIARAKAAAGKDFPVFGNGDVFSPEAAKLMLDSTGCDGVLVARGTMGAPWI
ARQIEDYLTTGTYQKMPFSTRKQAFLQHLHWVEEYYQSEAKFLCETRKLCGHYLISAAKVRFLRSALSKATSVQAVYQLI
EAYEESDDEPRDQPDLNKC
>Mature_338_residues
ASSIHIGNILLKSPIVYAPLAGFSDYPYRRMSSLYGLPALMFCEMVKIEGLHYSPSRTLKLLEYSESMRPIGGQLCGSKP
EMAGEAAKVLEGLGFDLIDLNCGCPTDRITKDGSGSGLLKTPELIGKVLEKIIGSVSIPVTVKIRSGWDGNNINVEETVR
IIKEAGASAVFVHGRTRAQGYVGPSNLEYIARAKAAAGKDFPVFGNGDVFSPEAAKLMLDSTGCDGVLVARGTMGAPWIA
RQIEDYLTTGTYQKMPFSTRKQAFLQHLHWVEEYYQSEAKFLCETRKLCGHYLISAAKVRFLRSALSKATSVQAVYQLIE
AYEESDDEPRDQPDLNKC

Specific function: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs [H]

COG id: COG0042

COG function: function code J; tRNA-dihydrouridine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dus family [H]

Homologues:

Organism=Homo sapiens, GI239788483, Length=292, Percent_Identity=27.0547945205479, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI239788462, Length=285, Percent_Identity=26.6666666666667, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI31742496, Length=278, Percent_Identity=26.2589928057554, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40807366, Length=296, Percent_Identity=25.6756756756757, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI8923374, Length=336, Percent_Identity=24.1071428571429, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1789660, Length=325, Percent_Identity=30.1538461538462, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1788462, Length=241, Percent_Identity=30.2904564315353, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI145693211, Length=241, Percent_Identity=28.6307053941909, Blast_Score=85, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17543114, Length=239, Percent_Identity=28.0334728033473, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25144369, Length=226, Percent_Identity=26.5486725663717, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17507177, Length=315, Percent_Identity=22.8571428571429, Blast_Score=81, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323433, Length=307, Percent_Identity=28.9902280130293, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323560, Length=342, Percent_Identity=26.0233918128655, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323437, Length=235, Percent_Identity=25.1063829787234, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24585320, Length=290, Percent_Identity=31.7241379310345, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24580595, Length=229, Percent_Identity=28.82096069869, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19920448, Length=229, Percent_Identity=28.82096069869, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19921524, Length=225, Percent_Identity=27.5555555555556, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004652
- InterPro:   IPR001269
- InterPro:   IPR018517 [H]

Pfam domain/function: PF01207 Dus [H]

EC number: NA

Molecular weight: Translated: 37151; Mature: 37020

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS01136 UPF0034

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSIHIGNILLKSPIVYAPLAGFSDYPYRRMSSLYGLPALMFCEMVKIEGLHYSPSRTL
CCCCEECCHHHHHCCCCEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEECHHHHH
KLLEYSESMRPIGGQLCGSKPEMAGEAAKVLEGLGFDLIDLNCGCPTDRITKDGSGSGLL
HHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCC
KTPELIGKVLEKIIGSVSIPVTVKIRSGWDGNNINVEETVRIIKEAGASAVFVHGRTRAQ
CCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
GYVGPSNLEYIARAKAAAGKDFPVFGNGDVFSPEAAKLMLDSTGCDGVLVARGTMGAPWI
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCEECCHHHHEEEECCCCCEEEEECCCCCCHHH
ARQIEDYLTTGTYQKMPFSTRKQAFLQHLHWVEEYYQSEAKFLCETRKLCGHYLISAAKV
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFLRSALSKATSVQAVYQLIEAYEESDDEPRDQPDLNKC
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASSIHIGNILLKSPIVYAPLAGFSDYPYRRMSSLYGLPALMFCEMVKIEGLHYSPSRTL
CCCEECCHHHHHCCCCEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEECHHHHH
KLLEYSESMRPIGGQLCGSKPEMAGEAAKVLEGLGFDLIDLNCGCPTDRITKDGSGSGLL
HHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCC
KTPELIGKVLEKIIGSVSIPVTVKIRSGWDGNNINVEETVRIIKEAGASAVFVHGRTRAQ
CCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
GYVGPSNLEYIARAKAAAGKDFPVFGNGDVFSPEAAKLMLDSTGCDGVLVARGTMGAPWI
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCEECCHHHHEEEECCCCCEEEEECCCCCCHHH
ARQIEDYLTTGTYQKMPFSTRKQAFLQHLHWVEEYYQSEAKFLCETRKLCGHYLISAAKV
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFLRSALSKATSVQAVYQLIEAYEESDDEPRDQPDLNKC
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]