Click here to switch to the map view.

The map label for this gene is psaA [H]

Identifier: 89257177

GI number: 89257177

Start: 1865895

End: 1866812

Strand: Reverse

Name: psaA [H]

Synonym: FTL_1936

Alternate gene names: 89257177

Gene position: 1866812-1865895 (Counterclockwise)

Preceding gene: 89257178

Following gene: 89257176

Centisome position: 98.46

GC content: 34.53

Gene sequence:

>918_bases
ATGAAAAAATACATACTAATAGCTTTAGCTGCTGTTGTTATTGTAGCTTTGGTAGCTATCAACCTTTTGGCTGAAAGTGA
TAAGCCCCAAACAACAAAAGGCAGTCATGACATCTCTGTTGTAGCTGCGGAAAACCAGTATGGCAGTATCGCTAAGCTTA
TTGGTGGTAGTAATGTTAAAGTTACTAATATAATCGATAATGCTGATGGTGATCCACATACTTTTGTCTCTTCTGTGAAA
AATGCTAAGCTTTTAGCCGAAGCAGATGTAATTATCTATAATGGTGCTGATTATGACTCATGGATTACGCCTATACTAAA
GACTAATAAAAATGCCGAAATCATTAAGGTACAAGACCTGATAAACTATCCACAAACCGAAAAACTTGGCATTAATCCAC
ACCTTTGGTATGATCCTGATACATTCCCAGCTTTGGCAGCTAAACTAAAAGATGTTTTTTCTAAGCAAGATTCTGTTGAT
AATAGCTTATTTGAAAAAAATCTTGAAAACTTTAACCATAAATATCAAAAAGTTTATGACCTAGTTAAACAAATAAAGCA
GTCAAGCTCAGGTACTCCTGTAACTGCTACAGAACCATTATTTGGCTATATGGCTAATGCACTAGGACTAGATATGAAAG
GCCTTGCATTTCAATGGGTGATAATGAATGACTCCGAACCTAGCCCTAAAATGATGATTAATTATCAGAAACTCTTTAAC
GATAAACAAGTTAAAGTGCTTTTCTATAACAAACAAGTCACAGATAATGTTACAAGTGATGTCTTGGAAGTTGCTAAGAA
AAATAATATACCAGTAGTTGGTATCACCGAAACTATGCCTGTAAATTATGATGCTATCAACTGGATGATTGAAACATTAC
AAGCAACTGCTGTGGCATTGGATAAAGTACAAAAATAA

Upstream 100 bases:

>100_bases
TATTTATTAAAGATTCTAATAACTAGAATATATACTACTTTACTCTCGCTTTTTTTTATTCTATTATTTGTTGTACAAAA
ATTTTAATACCATATAAATC

Downstream 100 bases:

>100_bases
AATGATTAAATGCTCTAACTTGGTGATTGGCTATAATAAACCAATCACAGCTGCGCTAAACCTAGAGGTACCAACAAATG
CATGGGTTGGTATCGTTGGT

Product: periplasmic solute binding family protein

Products: NA

Alternate protein names: Pneumococcal surface adhesin A [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKKYILIALAAVVIVALVAINLLAESDKPQTTKGSHDISVVAAENQYGSIAKLIGGSNVKVTNIIDNADGDPHTFVSSVK
NAKLLAEADVIIYNGADYDSWITPILKTNKNAEIIKVQDLINYPQTEKLGINPHLWYDPDTFPALAAKLKDVFSKQDSVD
NSLFEKNLENFNHKYQKVYDLVKQIKQSSSGTPVTATEPLFGYMANALGLDMKGLAFQWVIMNDSEPSPKMMINYQKLFN
DKQVKVLFYNKQVTDNVTSDVLEVAKKNNIPVVGITETMPVNYDAINWMIETLQATAVALDKVQK

Sequences:

>Translated_305_residues
MKKYILIALAAVVIVALVAINLLAESDKPQTTKGSHDISVVAAENQYGSIAKLIGGSNVKVTNIIDNADGDPHTFVSSVK
NAKLLAEADVIIYNGADYDSWITPILKTNKNAEIIKVQDLINYPQTEKLGINPHLWYDPDTFPALAAKLKDVFSKQDSVD
NSLFEKNLENFNHKYQKVYDLVKQIKQSSSGTPVTATEPLFGYMANALGLDMKGLAFQWVIMNDSEPSPKMMINYQKLFN
DKQVKVLFYNKQVTDNVTSDVLEVAKKNNIPVVGITETMPVNYDAINWMIETLQATAVALDKVQK
>Mature_305_residues
MKKYILIALAAVVIVALVAINLLAESDKPQTTKGSHDISVVAAENQYGSIAKLIGGSNVKVTNIIDNADGDPHTFVSSVK
NAKLLAEADVIIYNGADYDSWITPILKTNKNAEIIKVQDLINYPQTEKLGINPHLWYDPDTFPALAAKLKDVFSKQDSVD
NSLFEKNLENFNHKYQKVYDLVKQIKQSSSGTPVTATEPLFGYMANALGLDMKGLAFQWVIMNDSEPSPKMMINYQKLFN
DKQVKVLFYNKQVTDNVTSDVLEVAKKNNIPVVGITETMPVNYDAINWMIETLQATAVALDKVQK

Specific function: Part of an ATP-driven transport system for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 33815; Mature: 33815

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYILIALAAVVIVALVAINLLAESDKPQTTKGSHDISVVAAENQYGSIAKLIGGSNVK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCCEE
VTNIIDNADGDPHTFVSSVKNAKLLAEADVIIYNGADYDSWITPILKTNKNAEIIKVQDL
EEEEECCCCCCHHHHHHHHCCCEEEEECCEEEEECCCCHHHHHHHHHCCCCCCEEEEHHH
INYPQTEKLGINPHLWYDPDTFPALAAKLKDVFSKQDSVDNSLFEKNLENFNHKYQKVYD
HCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LVKQIKQSSSGTPVTATEPLFGYMANALGLDMKGLAFQWVIMNDSEPSPKMMINYQKLFN
HHHHHHHCCCCCCCEECCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHEEEHHHHCC
DKQVKVLFYNKQVTDNVTSDVLEVAKKNNIPVVGITETMPVNYDAINWMIETLQATAVAL
CCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
DKVQK
HHHCC
>Mature Secondary Structure
MKKYILIALAAVVIVALVAINLLAESDKPQTTKGSHDISVVAAENQYGSIAKLIGGSNVK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCCEE
VTNIIDNADGDPHTFVSSVKNAKLLAEADVIIYNGADYDSWITPILKTNKNAEIIKVQDL
EEEEECCCCCCHHHHHHHHCCCEEEEECCEEEEECCCCHHHHHHHHHCCCCCCEEEEHHH
INYPQTEKLGINPHLWYDPDTFPALAAKLKDVFSKQDSVDNSLFEKNLENFNHKYQKVYD
HCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LVKQIKQSSSGTPVTATEPLFGYMANALGLDMKGLAFQWVIMNDSEPSPKMMINYQKLFN
HHHHHHHCCCCCCCEECCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHEEEHHHHCC
DKQVKVLFYNKQVTDNVTSDVLEVAKKNNIPVVGITETMPVNYDAINWMIETLQATAVAL
CCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
DKVQK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8945574; 9767595; 11463916; 9379902 [H]