BacMap

Definition	Francisella tularensis subsp. holarctica LVS chromosome, complete genome.
Accession	NC_007880
Length	1,895,994

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The map label for this gene is kdpB [H]

Identifier: 89257132

GI number: 89257132

Start: 1813436

End: 1814341

Strand: Reverse

Name: kdpB [H]

Synonym: FTL_1881

Alternate gene names: 89257132

Gene position: 1814341-1813436 (Counterclockwise)

Preceding gene: 89257133

Following gene: 89257131

Centisome position: 95.69

GC content: 36.87

Gene sequence:

>906_bases
ATGAGTGGTATTGATTATCAAGGTTTAGAAGTAAGAAAAGGAGCTATATCATCGATAGAAAATTATCTTAAGGATAAGCT
TGATAGTAGCTTAATAAATATGTTTAGAAAAGTTACTGAGCAAATATCTGAGCAAGGAGGTACTCCTCTAGCGGTAGCTC
AAAAAGATAAATTACTAGGTGTGATTCATCTTAAAGATATTATAAAACCACGAATAAAAGAGCGTTTTGAAGAGTTGCGT
AAAATGGGCGTACAAACTGTTATGATAACAGGGGATAACCCATTAACCGCGGCTGCGATAGCTGCTGAAGCAGGTGTTGA
TGATTTTGTTGCTCAAGCTTCTCCTCAAGATAAGCTAGATTTTATAATCAAAGCACAAAAAGAGGGTAAAACAGTAGCAA
TGTGTGGTGATGGTACAAATGATGCTCCAGCTCTTGCTCAAGCTGACGTCGGTATTGCTATGGCAACAGGTACTTCTGCA
GCTAGAGAAGCCGGCAATATGGTTGATCTAGACTCAGATCCAAAGAAGATTATAGAAATAGTCAAAATTGGTAAGCAAAT
ATTAGTAACCAGAGGAGCATTAACAACGTTTAGTATAACTAATGATATTGCTAAGTATTTCGTGGTCATTCCTGCATTAT
TTGTAAATGCTTTTCCAAGCCTCGGAGCGCTTAATTTTATGGGACTGCATTCATCAACAAGTGCGATACTATCAGCAGTT
ATATTTAATGCATTGATTATCATATTTTTGATACCGATGGCTCTAGTTGGTGTAAAAAATGTAGTAGCTTCATCGCAGAC
TTTATTGCGTAGAAATCTACTCTACTACGGTGTTGGCGGTGCGATAGTACCTTTTATAGGTATTAAGCTTATAGATATGC
TTATTACAGCTATGCACTTGGTTTAG

Upstream 100 bases:

>100_bases
AAATCTATAGTCAAGTTAGCAGAACAGCGTTTTAACTTTAATTCAAAAGATGTAGATATTATCTCAAGCTGAGATTATAC
CATTCTCAGCATATACAAGA

Downstream 100 bases:

>100_bases
GCGAGGAGGTTACACCATGAAAAATTTACTTAAATCTTTTATCGCGATGCTTTTCTTTACAGTATTGCTTGGTTTAATTT
ACCCATTTTTTGTAATGGCA

Product: haloacid dehalogenase-like hydrolase

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] B chain; Potassium-binding and translocating subunit B; Potassium-translocating ATPase B chain [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSGIDYQGLEVRKGAISSIENYLKDKLDSSLINMFRKVTEQISEQGGTPLAVAQKDKLLGVIHLKDIIKPRIKERFEELR
KMGVQTVMITGDNPLTAAAIAAEAGVDDFVAQASPQDKLDFIIKAQKEGKTVAMCGDGTNDAPALAQADVGIAMATGTSA
AREAGNMVDLDSDPKKIIEIVKIGKQILVTRGALTTFSITNDIAKYFVVIPALFVNAFPSLGALNFMGLHSSTSAILSAV
IFNALIIIFLIPMALVGVKNVVASSQTLLRRNLLYYGVGGAIVPFIGIKLIDMLITAMHLV

Sequences:

>Translated_301_residues
MSGIDYQGLEVRKGAISSIENYLKDKLDSSLINMFRKVTEQISEQGGTPLAVAQKDKLLGVIHLKDIIKPRIKERFEELR
KMGVQTVMITGDNPLTAAAIAAEAGVDDFVAQASPQDKLDFIIKAQKEGKTVAMCGDGTNDAPALAQADVGIAMATGTSA
AREAGNMVDLDSDPKKIIEIVKIGKQILVTRGALTTFSITNDIAKYFVVIPALFVNAFPSLGALNFMGLHSSTSAILSAV
IFNALIIIFLIPMALVGVKNVVASSQTLLRRNLLYYGVGGAIVPFIGIKLIDMLITAMHLV
>Mature_300_residues
SGIDYQGLEVRKGAISSIENYLKDKLDSSLINMFRKVTEQISEQGGTPLAVAQKDKLLGVIHLKDIIKPRIKERFEELRK
MGVQTVMITGDNPLTAAAIAAEAGVDDFVAQASPQDKLDFIIKAQKEGKTVAMCGDGTNDAPALAQADVGIAMATGTSAA
REAGNMVDLDSDPKKIIEIVKIGKQILVTRGALTTFSITNDIAKYFVVIPALFVNAFPSLGALNFMGLHSSTSAILSAVI
FNALIIIFLIPMALVGVKNVVASSQTLLRRNLLYYGVGGAIVPFIGIKLIDMLITAMHLV

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions [H]

COG id: COG2216

COG function: function code P; High-affinity K+ transport system, ATPase chain B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=142, Percent_Identity=39.4366197183099, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI55743071, Length=142, Percent_Identity=40.1408450704225, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI55743073, Length=144, Percent_Identity=39.5833333333333, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI48762689, Length=202, Percent_Identity=32.1782178217822, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI48762685, Length=202, Percent_Identity=32.1782178217822, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI48762691, Length=202, Percent_Identity=32.1782178217822, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI48762687, Length=202, Percent_Identity=32.1782178217822, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI118498343, Length=201, Percent_Identity=31.3432835820896, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI297374799, Length=202, Percent_Identity=27.7227722772277, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI83700225, Length=202, Percent_Identity=27.7227722772277, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI28373107, Length=179, Percent_Identity=27.9329608938547, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI28373109, Length=179, Percent_Identity=27.9329608938547, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI28373115, Length=179, Percent_Identity=27.9329608938547, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI28373111, Length=179, Percent_Identity=27.9329608938547, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI28373105, Length=179, Percent_Identity=27.9329608938547, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI28373103, Length=179, Percent_Identity=27.9329608938547, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI28373113, Length=179, Percent_Identity=27.9329608938547, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI51944966, Length=200, Percent_Identity=27, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI237681111, Length=202, Percent_Identity=25.7425742574257, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI21361181, Length=202, Percent_Identity=25.7425742574257, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI237681109, Length=202, Percent_Identity=25.7425742574257, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4502271, Length=206, Percent_Identity=25.7281553398058, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI22748667, Length=202, Percent_Identity=25.2475247524752, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI209413709, Length=184, Percent_Identity=26.6304347826087, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI24638454, Length=183, Percent_Identity=26.775956284153, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4502285, Length=183, Percent_Identity=26.775956284153, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI153946397, Length=202, Percent_Identity=25.7425742574257, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1786914, Length=301, Percent_Identity=61.1295681063123, Blast_Score=336, Evalue=9e-94,
Organism=Escherichia coli, GI1786691, Length=127, Percent_Identity=47.244094488189, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789879, Length=153, Percent_Identity=33.9869281045752, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI2367363, Length=261, Percent_Identity=24.904214559387, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17556548, Length=135, Percent_Identity=36.2962962962963, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI193210130, Length=183, Percent_Identity=27.3224043715847, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17554158, Length=183, Percent_Identity=27.3224043715847, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71988506, Length=179, Percent_Identity=27.3743016759777, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17559224, Length=203, Percent_Identity=26.1083743842365, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17541776, Length=195, Percent_Identity=27.6923076923077, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25152707, Length=185, Percent_Identity=28.6486486486486, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71999438, Length=185, Percent_Identity=28.6486486486486, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71999440, Length=185, Percent_Identity=28.6486486486486, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997262, Length=224, Percent_Identity=26.3392857142857, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71997275, Length=175, Percent_Identity=29.1428571428571, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71997269, Length=207, Percent_Identity=27.536231884058, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6321271, Length=175, Percent_Identity=33.7142857142857, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320475, Length=131, Percent_Identity=40.4580152671756, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321432, Length=175, Percent_Identity=30.2857142857143, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6325221, Length=190, Percent_Identity=31.0526315789474, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321430, Length=190, Percent_Identity=31.0526315789474, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319772, Length=206, Percent_Identity=23.3009708737864, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221329854, Length=129, Percent_Identity=41.8604651162791, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24668708, Length=193, Percent_Identity=31.0880829015544, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281366617, Length=193, Percent_Identity=31.0880829015544, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24668704, Length=193, Percent_Identity=31.0880829015544, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24668696, Length=193, Percent_Identity=31.0880829015544, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI161085803, Length=193, Percent_Identity=31.0880829015544, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281366676, Length=214, Percent_Identity=26.1682242990654, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45553437, Length=203, Percent_Identity=25.1231527093596, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45553435, Length=203, Percent_Identity=25.1231527093596, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45553439, Length=203, Percent_Identity=25.1231527093596, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45553441, Length=203, Percent_Identity=25.1231527093596, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648580, Length=203, Percent_Identity=25.1231527093596, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648578, Length=203, Percent_Identity=25.1231527093596, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362164, Length=203, Percent_Identity=25.1231527093596, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648576, Length=203, Percent_Identity=25.1231527093596, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648582, Length=203, Percent_Identity=25.1231527093596, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR000150
- InterPro:   IPR006391 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: =3.6.3.12 [H]

Molecular weight: Translated: 32175; Mature: 32044

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGIDYQGLEVRKGAISSIENYLKDKLDSSLINMFRKVTEQISEQGGTPLAVAQKDKLLG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHEE
VIHLKDIIKPRIKERFEELRKMGVQTVMITGDNPLTAAAIAAEAGVDDFVAQASPQDKLD
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCHHHHHHCCCCCHHHH
FIIKAQKEGKTVAMCGDGTNDAPALAQADVGIAMATGTSAAREAGNMVDLDSDPKKIIEI
HHEEECCCCCEEEEECCCCCCCCCHHHCCCCEEEECCCHHHHHCCCCCCCCCCHHHHHHH
VKIGKQILVTRGALTTFSITNDIAKYFVVIPALFVNAFPSLGALNFMGLHSSTSAILSAV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCHHHHHHHHH
IFNALIIIFLIPMALVGVKNVVASSQTLLRRNLLYYGVGGAIVPFIGIKLIDMLITAMHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHC
V
C
>Mature Secondary Structure 
SGIDYQGLEVRKGAISSIENYLKDKLDSSLINMFRKVTEQISEQGGTPLAVAQKDKLLG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHEE
VIHLKDIIKPRIKERFEELRKMGVQTVMITGDNPLTAAAIAAEAGVDDFVAQASPQDKLD
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCHHHHHHCCCCCHHHH
FIIKAQKEGKTVAMCGDGTNDAPALAQADVGIAMATGTSAAREAGNMVDLDSDPKKIIEI
HHEEECCCCCEEEEECCCCCCCCCHHHCCCCEEEECCCHHHHHCCCCCCCCCCHHHHHHH
VKIGKQILVTRGALTTFSITNDIAKYFVVIPALFVNAFPSLGALNFMGLHSSTSAILSAV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCHHHHHHHHH
IFNALIIIFLIPMALVGVKNVVASSQTLLRRNLLYYGVGGAIVPFIGIKLIDMLITAMHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]