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The map label for this gene is gltA [H]

Identifier: 89257052

GI number: 89257052

Start: 1721274

End: 1722533

Strand: Direct

Name: gltA [H]

Synonym: FTL_1789

Alternate gene names: 89257052

Gene position: 1721274-1722533 (Clockwise)

Preceding gene: 89257040

Following gene: 89257053

Centisome position: 90.78

GC content: 36.51

Gene sequence:

>1260_bases
ATGAGTAAATACGCAACTCTTAAGTATGCAGATAAAAATATTGAAATAGAATTACCAGTATATTCTCCTAGCTTGGGTAA
TGACTGCATAGATGTTTCATCATTAGTAAAACACGGAATTTTTACTTATGATCCTGGATTCATGTCTACAGCTGCATGCG
AATCTAAAATTACATATATCGATGGTGGTAAAGGTGTACTTTTACATAGAGGCTACCCAATCGAAGAATGGACTCAAAAA
TCAAACTACAGAACTCTTTGCTATGCATTGATTTATGGCGAACTCCCAACAGATGAACAGGTTAAAAGCTTTAGACAAGA
AATTATCAATAAAATGCCAGTATGCGAGCATGTCAAAGCTGCAATAGCTGCAATGCCTCAACATACACATCCAATGTCAA
GCTTAATAGCTGGTGTTAATGTCTTAGCTGCTGAACATATCCACAATGGACAAAAAGAATCTCAAGATGAAGTCGCAAAA
AATATCGTAGCAAAAATTGCAACTATAGCAGCCATGGCTTACAGACATAATCACGGCAAGAAATTCTTAGAACCTAAAAT
GGAATATGGCTATGCTGAGAATTTCTTGTATATGATGTTTGCTGATGATGAGAGCTACAAACCAGATGAGCTACATATCA
AAGCAATGGATACAATATTTATGCTTCATGCTGATCACGAGCAAAATGCTTCAACATCAACTGTAAGGTTATCAGGATCA
ACTGGTAACTCTCCTTATGCGGCAATTATCGCAGGCATTACCGCATTATGGGGACCTGCTCATGGCGGCGCTAATGAAGC
TGTGCTTAAAATGTTATCTGAAATTGGTAGCACTGAGAATATCGATAAGTATATTGCTAAAGCGAAAGATAAAGATGATC
CATTTAGATTAATGGGCTTTGGACATAGAGTCTACAAAAATACTGATCCGAGAGCTACTGCAATGAAAAAGAACTGTGAA
GAAATACTTGCTAAACTTGGTCATAGTGATAACCCTCTTCTCACAGTAGCTAAAAAACTAGAAGAAATTGCTTTACAAGA
TGAGTTCTTTATCGAGAGAAAGCTTTTCTCTAATGTTGATTTTTACTCAGGTATAATCTTAAAAGCCATGGGCATTCCAG
AAGATATGTTTACAGCCATATTTGCTCTAGCAAGAACATCAGGGTGGATATCTCAATGGATAGAGATGGTTAATGATCCT
GCTCAAAAGATTGGTCGTCCAAGACAATTATATACTGGTGCAACAAATAGAAATTTCTAA

Upstream 100 bases:

>100_bases
TGATACCTTATAACTATTTTCTTTTTTGACGAAAGGTATCTTTTTACTGCAAAACCTTGCATTATAGTTTCGATCAACTC
TTCACTTGGAGGTCATGTTA

Downstream 100 bases:

>100_bases
TTTTATTTTTTTTGCTCTATTCTTTATTTACTTTCTTAGTTATTTCAACTAGCATTTTATCTATATAAAAAATCCATATA
GATAAGAAATGACTAGTTCT

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSKYATLKYADKNIEIELPVYSPSLGNDCIDVSSLVKHGIFTYDPGFMSTAACESKITYIDGGKGVLLHRGYPIEEWTQK
SNYRTLCYALIYGELPTDEQVKSFRQEIINKMPVCEHVKAAIAAMPQHTHPMSSLIAGVNVLAAEHIHNGQKESQDEVAK
NIVAKIATIAAMAYRHNHGKKFLEPKMEYGYAENFLYMMFADDESYKPDELHIKAMDTIFMLHADHEQNASTSTVRLSGS
TGNSPYAAIIAGITALWGPAHGGANEAVLKMLSEIGSTENIDKYIAKAKDKDDPFRLMGFGHRVYKNTDPRATAMKKNCE
EILAKLGHSDNPLLTVAKKLEEIALQDEFFIERKLFSNVDFYSGIILKAMGIPEDMFTAIFALARTSGWISQWIEMVNDP
AQKIGRPRQLYTGATNRNF

Sequences:

>Translated_419_residues
MSKYATLKYADKNIEIELPVYSPSLGNDCIDVSSLVKHGIFTYDPGFMSTAACESKITYIDGGKGVLLHRGYPIEEWTQK
SNYRTLCYALIYGELPTDEQVKSFRQEIINKMPVCEHVKAAIAAMPQHTHPMSSLIAGVNVLAAEHIHNGQKESQDEVAK
NIVAKIATIAAMAYRHNHGKKFLEPKMEYGYAENFLYMMFADDESYKPDELHIKAMDTIFMLHADHEQNASTSTVRLSGS
TGNSPYAAIIAGITALWGPAHGGANEAVLKMLSEIGSTENIDKYIAKAKDKDDPFRLMGFGHRVYKNTDPRATAMKKNCE
EILAKLGHSDNPLLTVAKKLEEIALQDEFFIERKLFSNVDFYSGIILKAMGIPEDMFTAIFALARTSGWISQWIEMVNDP
AQKIGRPRQLYTGATNRNF
>Mature_418_residues
SKYATLKYADKNIEIELPVYSPSLGNDCIDVSSLVKHGIFTYDPGFMSTAACESKITYIDGGKGVLLHRGYPIEEWTQKS
NYRTLCYALIYGELPTDEQVKSFRQEIINKMPVCEHVKAAIAAMPQHTHPMSSLIAGVNVLAAEHIHNGQKESQDEVAKN
IVAKIATIAAMAYRHNHGKKFLEPKMEYGYAENFLYMMFADDESYKPDELHIKAMDTIFMLHADHEQNASTSTVRLSGST
GNSPYAAIIAGITALWGPAHGGANEAVLKMLSEIGSTENIDKYIAKAKDKDDPFRLMGFGHRVYKNTDPRATAMKKNCEE
ILAKLGHSDNPLLTVAKKLEEIALQDEFFIERKLFSNVDFYSGIILKAMGIPEDMFTAIFALARTSGWISQWIEMVNDPA
QKIGRPRQLYTGATNRNF

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=356, Percent_Identity=25.8426966292135, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI1786939, Length=408, Percent_Identity=52.4509803921569, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1786527, Length=366, Percent_Identity=29.7814207650273, Blast_Score=164, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17555174, Length=383, Percent_Identity=26.1096605744125, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324328, Length=373, Percent_Identity=29.2225201072386, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319850, Length=352, Percent_Identity=28.4090909090909, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6325257, Length=362, Percent_Identity=27.3480662983425, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24640124, Length=400, Percent_Identity=27, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24640126, Length=400, Percent_Identity=27, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI21356863, Length=374, Percent_Identity=25.668449197861, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 46795; Mature: 46664

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYATLKYADKNIEIELPVYSPSLGNDCIDVSSLVKHGIFTYDPGFMSTAACESKITYI
CCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHCCCEEECCCCCHHHHHCCEEEEE
DGGKGVLLHRGYPIEEWTQKSNYRTLCYALIYGELPTDEQVKSFRQEIINKMPVCEHVKA
ECCCEEEEECCCCHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHH
AIAAMPQHTHPMSSLIAGVNVLAAEHIHNGQKESQDEVAKNIVAKIATIAAMAYRHNHGK
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
KFLEPKMEYGYAENFLYMMFADDESYKPDELHIKAMDTIFMLHADHEQNASTSTVRLSGS
HHHCHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEEEEECCCCCCCCCCEEEEECC
TGNSPYAAIIAGITALWGPAHGGANEAVLKMLSEIGSTENIDKYIAKAKDKDDPFRLMGF
CCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHCC
GHRVYKNTDPRATAMKKNCEEILAKLGHSDNPLLTVAKKLEEIALQDEFFIERKLFSNVD
CHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FYSGIILKAMGIPEDMFTAIFALARTSGWISQWIEMVNDPAQKIGRPRQLYTGATNRNF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure 
SKYATLKYADKNIEIELPVYSPSLGNDCIDVSSLVKHGIFTYDPGFMSTAACESKITYI
CCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHCCCEEECCCCCHHHHHCCEEEEE
DGGKGVLLHRGYPIEEWTQKSNYRTLCYALIYGELPTDEQVKSFRQEIINKMPVCEHVKA
ECCCEEEEECCCCHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHH
AIAAMPQHTHPMSSLIAGVNVLAAEHIHNGQKESQDEVAKNIVAKIATIAAMAYRHNHGK
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
KFLEPKMEYGYAENFLYMMFADDESYKPDELHIKAMDTIFMLHADHEQNASTSTVRLSGS
HHHCHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEEEEECCCCCCCCCCEEEEECC
TGNSPYAAIIAGITALWGPAHGGANEAVLKMLSEIGSTENIDKYIAKAKDKDDPFRLMGF
CCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHCC
GHRVYKNTDPRATAMKKNCEEILAKLGHSDNPLLTVAKKLEEIALQDEFFIERKLFSNVD
CHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FYSGIILKAMGIPEDMFTAIFALARTSGWISQWIEMVNDPAQKIGRPRQLYTGATNRNF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2507528; 10984043 [H]