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The map label for this gene is tpiA [H]

Identifier: 89257043

GI number: 89257043

Start: 1710663

End: 1711424

Strand: Reverse

Name: tpiA [H]

Synonym: FTL_1780

Alternate gene names: 89257043

Gene position: 1711424-1710663 (Counterclockwise)

Preceding gene: 89257044

Following gene: 89257042

Centisome position: 90.27

GC content: 34.25

Gene sequence:

>762_bases
ATGCAAAAATTAATAATGGGTAACTGGAAAATGAATGGTAACTCTACAAGCATAAAAGAGCTCTGTAGTGGTATATCACA
AGTGCAATATGATACTTCAAGAGTAGCTATTGCTGTTTTTCCATCAAGTGTTTATGTTAAAGAAGTAATCTCACAGCTGC
CAGAGAAAGTAGGTGTTGGTCTACAAAATATTACTTTTTATGATGATGGTGCTTATACTGGTGAGATATCTGCTAGGATG
TTGGAAGATATTGGTTGTGACTACTTACTAATTGGTCATTCTGAGAGAAGATCTCTATTTGCTGAGTCTGATGAAGATGT
TTTTAAAAAGCTTAACAAAATTATAGATACTACTATAACGCCAGTAGTGTGTATTGGTGAATCACTAGATGATAGAAAAA
GTGGTAAGCTCAAACAAGTTTTAGCAACACAACTAAGCTTAATCTTAGAAAATTTATCTGTTGAGCAGCTAGCAAAAGTC
GTAATTGCATATGAACCTGTCTGGGCAATAGGTACAGGAGTTGTGGCTTCACTAGAGCAGATTCAAGAAACACATCAATT
TATTCGTTCATTGTTAGCTAAAGTTGATGAAAGACTTGCTAAAAATATAAAAATAGTGTATGGTGGTAGCCTAAAAGCTG
AAAATGCTAAAGATATATTAAGCTTACCAGATGTTGACGGTGGTTTAATTGGTGGCGCATCTTTGAAGGCTGCAGAATTT
AACGAAATAATAAATCAAGCAAACAAGATATGTACGGAATAA

Upstream 100 bases:

>100_bases
AACCTGTTTTAAGAGTTATGGTTGAAGCAGATGACAAGAGTCTCGCTACAAACGAGGCTGAGTATTTGGTTGAAAAAGTA
AAACAAAAATTGGTGTAGAT

Downstream 100 bases:

>100_bases
TTTTAACTATTGATATTATCGCAGCTATTGCGATTGTGGTACTAGTGTTGCTGCAGCAAGGTAAGGGCGCTAATATGGGC
GTTTCTTTTGGAGCAGGAGC

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MQKLIMGNWKMNGNSTSIKELCSGISQVQYDTSRVAIAVFPSSVYVKEVISQLPEKVGVGLQNITFYDDGAYTGEISARM
LEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTITPVVCIGESLDDRKSGKLKQVLATQLSLILENLSVEQLAKV
VIAYEPVWAIGTGVVASLEQIQETHQFIRSLLAKVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAAEF
NEIINQANKICTE

Sequences:

>Translated_253_residues
MQKLIMGNWKMNGNSTSIKELCSGISQVQYDTSRVAIAVFPSSVYVKEVISQLPEKVGVGLQNITFYDDGAYTGEISARM
LEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTITPVVCIGESLDDRKSGKLKQVLATQLSLILENLSVEQLAKV
VIAYEPVWAIGTGVVASLEQIQETHQFIRSLLAKVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAAEF
NEIINQANKICTE
>Mature_253_residues
MQKLIMGNWKMNGNSTSIKELCSGISQVQYDTSRVAIAVFPSSVYVKEVISQLPEKVGVGLQNITFYDDGAYTGEISARM
LEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTITPVVCIGESLDDRKSGKLKQVLATQLSLILENLSVEQLAKV
VIAYEPVWAIGTGVVASLEQIQETHQFIRSLLAKVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAAEF
NEIINQANKICTE

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=245, Percent_Identity=41.6326530612245, Blast_Score=189, Evalue=1e-48,
Organism=Homo sapiens, GI226529917, Length=245, Percent_Identity=41.6326530612245, Blast_Score=189, Evalue=2e-48,
Organism=Escherichia coli, GI1790353, Length=247, Percent_Identity=42.5101214574899, Blast_Score=212, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17536593, Length=244, Percent_Identity=43.4426229508197, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6320255, Length=247, Percent_Identity=39.6761133603239, Blast_Score=172, Evalue=4e-44,
Organism=Drosophila melanogaster, GI28572008, Length=242, Percent_Identity=41.3223140495868, Blast_Score=194, Evalue=4e-50,
Organism=Drosophila melanogaster, GI28572006, Length=242, Percent_Identity=41.3223140495868, Blast_Score=194, Evalue=4e-50,
Organism=Drosophila melanogaster, GI28572004, Length=242, Percent_Identity=41.3223140495868, Blast_Score=194, Evalue=5e-50,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 27656; Mature: 27656

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLIMGNWKMNGNSTSIKELCSGISQVQYDTSRVAIAVFPSSVYVKEVISQLPEKVGVG
CCCEEECCEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
LQNITFYDDGAYTGEISARMLEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTIT
CCEEEEECCCCEECHHHHHHHHHCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHCC
PVVCIGESLDDRKSGKLKQVLATQLSLILENLSVEQLAKVVIAYEPVWAIGTGVVASLEQ
HHEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
IQETHQFIRSLLAKVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAAEF
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHCCCCCCCCEECCCCCCHHHH
NEIINQANKICTE
HHHHHHHHHHCCC
>Mature Secondary Structure
MQKLIMGNWKMNGNSTSIKELCSGISQVQYDTSRVAIAVFPSSVYVKEVISQLPEKVGVG
CCCEEECCEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
LQNITFYDDGAYTGEISARMLEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTIT
CCEEEEECCCCEECHHHHHHHHHCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHCC
PVVCIGESLDDRKSGKLKQVLATQLSLILENLSVEQLAKVVIAYEPVWAIGTGVVASLEQ
HHEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
IQETHQFIRSLLAKVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAAEF
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHCCCCCCCCEECCCCCCHHHH
NEIINQANKICTE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA