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The map label for this gene is rpoB [H]

Identifier: 89257013

GI number: 89257013

Start: 1677332

End: 1681408

Strand: Reverse

Name: rpoB [H]

Synonym: FTL_1744

Alternate gene names: 89257013

Gene position: 1681408-1677332 (Counterclockwise)

Preceding gene: 89257014

Following gene: 89257012

Centisome position: 88.68

GC content: 35.3

Gene sequence:

>4077_bases
ATGTCTTACTCATACGCTGAGAAAAAAAGAATTCGTAAAGAGTTTGGGGTTCTTCCTCATATCTTAGATGTACCATATTT
GCTTTCTATTCAAACAGAGTCATACAAAAAATTCTTGACTGTAGATGCAGCAAAAGGAAGACTTCACTCTGGACTTGAAA
TAGTTTTAAAACAGTCTTTTCCTGTTGAGAGTAAAAATGGTCAATATGAACTTCACTATGTTGATTATCAAATTGGTGAG
CCTACTTTTGATGAAACTGAATGTCAGGTTCGTGGTGCTACTTATGATGCACCATTAAATGTGAAGTTAAGATTAGTTGT
ATATAATAAAGATGCTCTTCCAAATGAGAAAATTGTCGAGGACATTAGAGAAGAGTATGTGTACATGGGCGATATTCCGC
TAATGACAACTAATGGTACTTTTATCATTAATGGGACAGAAAGAGTAGTAGTCTCTCAGTTGCATAGATCACCAGGGGCG
TTCTTTAGTAAGGATGACTCTGAGGAAGGAGCATTCTCAGCACGTATTATCCCATATAGAGGCTCATGGCTTGATTTTGA
ATTTGACTCAAAAGGTATTATATGGGCTAGGATTGATAGAAAAAGAAAATTCTGTGCTACAGTTATTTTAAAAGCTCTTG
GTTATACTCAAGAGCAAATATTAGAGAATTTTTCTGAGAGTAAGACTATTACTTTTAATAGTAAAGGTTTTGCTCTTAGA
CTTGATAACCTTTCAAATATGAAAGGTGAGCTGCTTAAGTTTGACATTGTAGATGCTCAAGATAATGTTATTGTTAAAAA
GAATAAAAAATTAACTTCAAGAGATGTTAAGAAAATTAAAGATGCAGGCGTTGACTCTGTAGCTATTGATTTTGATTTGG
TCAGCACTCTTAGAGTTGCAAAAGATATCGTTAATGAAGCAACAGGTGAAGTGATAGCTTATGCTAATGACGATGTTACA
GAAAGTTTATTAAAGTCATGCGTAGAAGTTGGCATGCTTGAATTAGAAGTTATTGATTTTATAACTACTGAAAGAGGTAG
GTATATATCTGATACTTTAAAATATGATCTTACAAGAAATACTGATGAGGCACTTGTCGAGATATATAAGGTATTACGAC
CAGGTGATCCTCCTGCAGCAGCTTCAGTTAAAGCATTATTTGAAGGTTTATTCTTTATTGAAAGTAGATATAGCCTTTCT
GATATTGGTAGAATGAAGCTAAATGCTAGATTAGGTTCGGATAAGGTATCTAAAGATATCTATACTTTAGAAAATAGTGA
TATAGTTGGCGTAATTGAAGAGCTTATAAATATCCGTGATGGTAAAGGTAAAGTTGATGATATTGATCATTTAGGTAACA
GACGTGTACGTTCTGTTGGCGAGATGGTTGAGAATCAGTTTAGAATAGGCCTCTACCGTGTAGAGAAAGGTATTCGTGAA
AGTATGTCTTTAGTACATAAAGATAAGCTTATGCCAAAAGATATCGTTAACTCGAAGCCAATCACAGCAGCAATTAAAGA
ATTCTTTACTTCTGGAGCGTTATCACAATTTATGGATCAAGATAACCCATTGTCAGAAGTTACACATAAGCGTAGAATAT
CTGCATTAGGTCCAGGTGGTTTATCACGTGATAGAGCAGGTTTTGAAGTACGTGATGTTCATGCAACACACTATGGTAGA
TTATGTCCAATTGAGACTCCAGAAGGTCCAAATATTGGTCTAATTAACTCATTAGCAAGTTATGCTCGTGTTAATGATTA
TGGTTTCTTAGAAGCACCATATCGAAAAGTTGTTGATGGTAAGGTTACAGATGAAATTGAATACTTATCTGCTATCGATG
AAGATAATTATGTAATTGCTCAAGCATCAACTAAACTTGATGAAAATAACCATTTTGTTGAAGATATTATTCAATGTCGT
TCTGGAGGTGAGGCAATATTTACTGAGTCAAGTAGAGTTCAGTATATGGATGTTTCTGCTAAACAGATGGTTTCAGCAGC
TGCGGCACTAATTCCTTTCCTTGAGCATGATGATGCTAACAGGGTATTGATGGGTGCAAACATGCAACGTCAAGCGGTAC
CGACTCTTAAATCTGAGAAGCCTTTAGTCGGTACAGGTATGGAGAAGATTGTTGCTAGAGATTCTGGTAATTGTATTATC
GCAAGAAATGTTGGTGAAGTGGCTGAAGTTGATTCTAACAGAATCGTTATTAAAGTAGATACTGAAAAATCACAAACTAG
TAATTTGGTTGATATTTATAGTTTAACTAAATTTAAACGCTCAAACAAAAATACTTGTATTAACCAGCGTCCAATAGTAA
ATGTGGGTGATAAAGTAGAAGCTGGTGATATTTTAGCGGATGGTTTTGCAACTGATTTTGGTGAATTGTCACTAGGGCAT
AACTTGATGGTTGCTTTTATGCCATGGAATGGTTATAACTTTGAGGATTCGATCTTACTATCTGAAAGAATAGTAAAAGA
TGATAAGTATACTAGTATCCATATTGAAGAGTTCACATGTGTGGCTCGTGATACTAAGCTTGGTCCTGAAGAGATAACTG
CAGATATTCCAAATGTTAGTGAGTCTAGTTTGGCAAAACTTGATGAATCAGGTATCGTCCATATTGGCGCTAATGTCGAA
GCAGGCGATATTTTGGTAGCTAAGATTACTCCAAAAGCTGAGCAACAACTAACTCCTGAAGAGAGACTACTTAGAGCAAT
CTTTAATGAAAAAGCATCAAATGTTGTTGATAGTTCATTAAGAATGCCAAGTGGTACTTCTGGTACGGTTATTAATGTTC
AAGTATTTGAGAATGACAAAGGTGGTAAAAGTAAGCGAGCTCTTAAGATTGAAAAAGAACTGATCGATAAAGCTCGTAAG
GATTTTGATGAGGAGTTTGCAGTAATTGAATCTGTAGTTAAATCATCAATTGAGCAAGAAGTTGTTGGTGCAAAAATCCA
AAAAGCAAAAGGTCTTAAAAAAGGTGCTATCCTTACAAAAGAATTTTTAGCAACACTACCTTTATCTAAATGGCTAGAAA
TTTCTTTTGAGGATGAGAAACTTGAAGAGAAAGTTCAAAACGCTAGAGAGTATTATGAGGAAGCTAAAATTGCTATAGAT
GCTAAATTTGAAGCTAAGAAAAAATCTATTACTCAGAGTAATGAGCTATCTCCAGGTGTGCTTAAGACTGTTAAAGTTTT
TGTTGCGATTAAAAAGCGTATCCAGCCAGGTGATAAGATGGCTGGTCGTCATGGTAACAAAGGTGTGGTTTCACGCGTAT
TACCAGTTGAAGATATGCCATATATGGAAGATGGTACTCCTGTAGACGTTTGTCTAAATCCTTTAGGTATCCCATCACGT
ATGAACATTGGGCAGATTTTAGAAGCACACTTAGGATTGGCTTCATATGGTTTAGGTAAAAAAATCGAAAAAACTTTAGA
GAAAACTAGAAAAGCAGCTGAACTAAGAAAGACTTTAGAAGAAGTATATAATAGCGTTGGCGATAAGAAAGTTAATCTTG
AGGCTTTAAATGACGAAGAGATACTAACTCTTTGTGACAACCTAAAAGGTGGAGTACCAATCGCTACACCAGTATTTGAT
GGTGCTAAAGAAGAAGATATTAAATCACTACTGAAAATAGGCGGCTTTGCAACTAATGGTCAGATGAAGCTTTTTGATGG
TCGTACTGGTAAGCCTTTTGATAGACATGTAACTGTTGGTTATATGTATATGCTAAAACTAGATCACTTAGTAGATGATA
AGATGCATGCAAGATCGACTGGCTCATATAGTCTAGTTACGCAGCAACCATTAGGTGGTAAAGCACAGTTTGGTGGACAA
AGATTCGGTGAGATGGAAGTTTGGGCATTACAAGCATATGGTGCTGCTTATACATTAAGAGAGATGCTAACAGTTAAGTC
AGATGACATAGCAGGTAGATCTAAAATGTATAAGAATATAGTTGATGGTAAGTTGACTATGAATGTAGATGTTCCAGAAT
CATTCAATGTTTTAAGAAATGAAGTTAGAGCATTGGGTATAGATATGGATTTTGACTATTCATCTGAGGAAGAATAA

Upstream 100 bases:

>100_bases
TCCCTAGTCTTTCTAGTATTGAAAGATACATAGATATTGGTGCAAATATAATCATATTTGCTTTTTATTTTGTGTAAACA
AAATCTTAGGGATGTTTTTG

Downstream 100 bases:

>100_bases
GCATCTTAATTTAAAGCTACTTATTTTTTGTTATTAAAATAAAAGTATAGGAGAATTACCAGTGAATAACGGTATCCTAC
ATCAAAATTACAATAGTAAA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1358; Mature: 1357

Protein sequence:

>1358_residues
MSYSYAEKKRIRKEFGVLPHILDVPYLLSIQTESYKKFLTVDAAKGRLHSGLEIVLKQSFPVESKNGQYELHYVDYQIGE
PTFDETECQVRGATYDAPLNVKLRLVVYNKDALPNEKIVEDIREEYVYMGDIPLMTTNGTFIINGTERVVVSQLHRSPGA
FFSKDDSEEGAFSARIIPYRGSWLDFEFDSKGIIWARIDRKRKFCATVILKALGYTQEQILENFSESKTITFNSKGFALR
LDNLSNMKGELLKFDIVDAQDNVIVKKNKKLTSRDVKKIKDAGVDSVAIDFDLVSTLRVAKDIVNEATGEVIAYANDDVT
ESLLKSCVEVGMLELEVIDFITTERGRYISDTLKYDLTRNTDEALVEIYKVLRPGDPPAAASVKALFEGLFFIESRYSLS
DIGRMKLNARLGSDKVSKDIYTLENSDIVGVIEELINIRDGKGKVDDIDHLGNRRVRSVGEMVENQFRIGLYRVEKGIRE
SMSLVHKDKLMPKDIVNSKPITAAIKEFFTSGALSQFMDQDNPLSEVTHKRRISALGPGGLSRDRAGFEVRDVHATHYGR
LCPIETPEGPNIGLINSLASYARVNDYGFLEAPYRKVVDGKVTDEIEYLSAIDEDNYVIAQASTKLDENNHFVEDIIQCR
SGGEAIFTESSRVQYMDVSAKQMVSAAAALIPFLEHDDANRVLMGANMQRQAVPTLKSEKPLVGTGMEKIVARDSGNCII
ARNVGEVAEVDSNRIVIKVDTEKSQTSNLVDIYSLTKFKRSNKNTCINQRPIVNVGDKVEAGDILADGFATDFGELSLGH
NLMVAFMPWNGYNFEDSILLSERIVKDDKYTSIHIEEFTCVARDTKLGPEEITADIPNVSESSLAKLDESGIVHIGANVE
AGDILVAKITPKAEQQLTPEERLLRAIFNEKASNVVDSSLRMPSGTSGTVINVQVFENDKGGKSKRALKIEKELIDKARK
DFDEEFAVIESVVKSSIEQEVVGAKIQKAKGLKKGAILTKEFLATLPLSKWLEISFEDEKLEEKVQNAREYYEEAKIAID
AKFEAKKKSITQSNELSPGVLKTVKVFVAIKKRIQPGDKMAGRHGNKGVVSRVLPVEDMPYMEDGTPVDVCLNPLGIPSR
MNIGQILEAHLGLASYGLGKKIEKTLEKTRKAAELRKTLEEVYNSVGDKKVNLEALNDEEILTLCDNLKGGVPIATPVFD
GAKEEDIKSLLKIGGFATNGQMKLFDGRTGKPFDRHVTVGYMYMLKLDHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQ
RFGEMEVWALQAYGAAYTLREMLTVKSDDIAGRSKMYKNIVDGKLTMNVDVPESFNVLRNEVRALGIDMDFDYSSEEE

Sequences:

>Translated_1358_residues
MSYSYAEKKRIRKEFGVLPHILDVPYLLSIQTESYKKFLTVDAAKGRLHSGLEIVLKQSFPVESKNGQYELHYVDYQIGE
PTFDETECQVRGATYDAPLNVKLRLVVYNKDALPNEKIVEDIREEYVYMGDIPLMTTNGTFIINGTERVVVSQLHRSPGA
FFSKDDSEEGAFSARIIPYRGSWLDFEFDSKGIIWARIDRKRKFCATVILKALGYTQEQILENFSESKTITFNSKGFALR
LDNLSNMKGELLKFDIVDAQDNVIVKKNKKLTSRDVKKIKDAGVDSVAIDFDLVSTLRVAKDIVNEATGEVIAYANDDVT
ESLLKSCVEVGMLELEVIDFITTERGRYISDTLKYDLTRNTDEALVEIYKVLRPGDPPAAASVKALFEGLFFIESRYSLS
DIGRMKLNARLGSDKVSKDIYTLENSDIVGVIEELINIRDGKGKVDDIDHLGNRRVRSVGEMVENQFRIGLYRVEKGIRE
SMSLVHKDKLMPKDIVNSKPITAAIKEFFTSGALSQFMDQDNPLSEVTHKRRISALGPGGLSRDRAGFEVRDVHATHYGR
LCPIETPEGPNIGLINSLASYARVNDYGFLEAPYRKVVDGKVTDEIEYLSAIDEDNYVIAQASTKLDENNHFVEDIIQCR
SGGEAIFTESSRVQYMDVSAKQMVSAAAALIPFLEHDDANRVLMGANMQRQAVPTLKSEKPLVGTGMEKIVARDSGNCII
ARNVGEVAEVDSNRIVIKVDTEKSQTSNLVDIYSLTKFKRSNKNTCINQRPIVNVGDKVEAGDILADGFATDFGELSLGH
NLMVAFMPWNGYNFEDSILLSERIVKDDKYTSIHIEEFTCVARDTKLGPEEITADIPNVSESSLAKLDESGIVHIGANVE
AGDILVAKITPKAEQQLTPEERLLRAIFNEKASNVVDSSLRMPSGTSGTVINVQVFENDKGGKSKRALKIEKELIDKARK
DFDEEFAVIESVVKSSIEQEVVGAKIQKAKGLKKGAILTKEFLATLPLSKWLEISFEDEKLEEKVQNAREYYEEAKIAID
AKFEAKKKSITQSNELSPGVLKTVKVFVAIKKRIQPGDKMAGRHGNKGVVSRVLPVEDMPYMEDGTPVDVCLNPLGIPSR
MNIGQILEAHLGLASYGLGKKIEKTLEKTRKAAELRKTLEEVYNSVGDKKVNLEALNDEEILTLCDNLKGGVPIATPVFD
GAKEEDIKSLLKIGGFATNGQMKLFDGRTGKPFDRHVTVGYMYMLKLDHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQ
RFGEMEVWALQAYGAAYTLREMLTVKSDDIAGRSKMYKNIVDGKLTMNVDVPESFNVLRNEVRALGIDMDFDYSSEEE
>Mature_1357_residues
SYSYAEKKRIRKEFGVLPHILDVPYLLSIQTESYKKFLTVDAAKGRLHSGLEIVLKQSFPVESKNGQYELHYVDYQIGEP
TFDETECQVRGATYDAPLNVKLRLVVYNKDALPNEKIVEDIREEYVYMGDIPLMTTNGTFIINGTERVVVSQLHRSPGAF
FSKDDSEEGAFSARIIPYRGSWLDFEFDSKGIIWARIDRKRKFCATVILKALGYTQEQILENFSESKTITFNSKGFALRL
DNLSNMKGELLKFDIVDAQDNVIVKKNKKLTSRDVKKIKDAGVDSVAIDFDLVSTLRVAKDIVNEATGEVIAYANDDVTE
SLLKSCVEVGMLELEVIDFITTERGRYISDTLKYDLTRNTDEALVEIYKVLRPGDPPAAASVKALFEGLFFIESRYSLSD
IGRMKLNARLGSDKVSKDIYTLENSDIVGVIEELINIRDGKGKVDDIDHLGNRRVRSVGEMVENQFRIGLYRVEKGIRES
MSLVHKDKLMPKDIVNSKPITAAIKEFFTSGALSQFMDQDNPLSEVTHKRRISALGPGGLSRDRAGFEVRDVHATHYGRL
CPIETPEGPNIGLINSLASYARVNDYGFLEAPYRKVVDGKVTDEIEYLSAIDEDNYVIAQASTKLDENNHFVEDIIQCRS
GGEAIFTESSRVQYMDVSAKQMVSAAAALIPFLEHDDANRVLMGANMQRQAVPTLKSEKPLVGTGMEKIVARDSGNCIIA
RNVGEVAEVDSNRIVIKVDTEKSQTSNLVDIYSLTKFKRSNKNTCINQRPIVNVGDKVEAGDILADGFATDFGELSLGHN
LMVAFMPWNGYNFEDSILLSERIVKDDKYTSIHIEEFTCVARDTKLGPEEITADIPNVSESSLAKLDESGIVHIGANVEA
GDILVAKITPKAEQQLTPEERLLRAIFNEKASNVVDSSLRMPSGTSGTVINVQVFENDKGGKSKRALKIEKELIDKARKD
FDEEFAVIESVVKSSIEQEVVGAKIQKAKGLKKGAILTKEFLATLPLSKWLEISFEDEKLEEKVQNAREYYEEAKIAIDA
KFEAKKKSITQSNELSPGVLKTVKVFVAIKKRIQPGDKMAGRHGNKGVVSRVLPVEDMPYMEDGTPVDVCLNPLGIPSRM
NIGQILEAHLGLASYGLGKKIEKTLEKTRKAAELRKTLEEVYNSVGDKKVNLEALNDEEILTLCDNLKGGVPIATPVFDG
AKEEDIKSLLKIGGFATNGQMKLFDGRTGKPFDRHVTVGYMYMLKLDHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQR
FGEMEVWALQAYGAAYTLREMLTVKSDDIAGRSKMYKNIVDGKLTMNVDVPESFNVLRNEVRALGIDMDFDYSSEEE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI33469941, Length=293, Percent_Identity=31.0580204778157, Blast_Score=130, Evalue=9e-30,
Organism=Homo sapiens, GI212286172, Length=293, Percent_Identity=31.0580204778157, Blast_Score=130, Evalue=9e-30,
Organism=Homo sapiens, GI4505941, Length=247, Percent_Identity=31.9838056680162, Blast_Score=120, Evalue=9e-27,
Organism=Homo sapiens, GI238908503, Length=257, Percent_Identity=28.4046692607004, Blast_Score=100, Evalue=2e-20,
Organism=Homo sapiens, GI238908505, Length=257, Percent_Identity=28.4046692607004, Blast_Score=100, Evalue=2e-20,
Organism=Escherichia coli, GI1790419, Length=1367, Percent_Identity=58.9612289685443, Blast_Score=1649, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=246, Percent_Identity=31.7073170731707, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17506623, Length=236, Percent_Identity=29.2372881355932, Blast_Score=106, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI25144348, Length=304, Percent_Identity=27.6315789473684, Blast_Score=98, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324781, Length=245, Percent_Identity=33.0612244897959, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324725, Length=248, Percent_Identity=32.258064516129, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325267, Length=251, Percent_Identity=30.2788844621514, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17647877, Length=245, Percent_Identity=32.2448979591837, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136444, Length=247, Percent_Identity=31.1740890688259, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17136446, Length=278, Percent_Identity=30.2158273381295, Blast_Score=107, Evalue=5e-23,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 151337; Mature: 151206

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSYAEKKRIRKEFGVLPHILDVPYLLSIQTESYKKFLTVDAAKGRLHSGLEIVLKQSF
CCCCHHHHHHHHHHHCCCCHHHCCCEEEEEECHHCCEEEEEECCCCCHHCCHHEEEECCC
PVESKNGQYELHYVDYQIGEPTFDETECQVRGATYDAPLNVKLRLVVYNKDALPNEKIVE
CCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCEECCCCCEEEEEEEEECCCCCCHHHHH
DIREEYVYMGDIPLMTTNGTFIINGTERVVVSQLHRSPGAFFSKDDSEEGAFSARIIPYR
HHHHCEEEECCEEEEEECCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEC
GSWLDFEFDSKGIIWARIDRKRKFCATVILKALGYTQEQILENFSESKTITFNSKGFALR
CCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCEEE
LDNLSNMKGELLKFDIVDAQDNVIVKKNKKLTSRDVKKIKDAGVDSVAIDFDLVSTLRVA
ECCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
KDIVNEATGEVIAYANDDVTESLLKSCVEVGMLELEVIDFITTERGRYISDTLKYDLTRN
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCHHEEHHHHHHCCCCCEEHHHHHCCCCCC
TDEALVEIYKVLRPGDPPAAASVKALFEGLFFIESRYSLSDIGRMKLNARLGSDKVSKDI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCEEEECCCCCCHHHCCE
YTLENSDIVGVIEELINIRDGKGKVDDIDHLGNRRVRSVGEMVENQFRIGLYRVEKGIRE
EEECCCCHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMSLVHKDKLMPKDIVNSKPITAAIKEFFTSGALSQFMDQDNPLSEVTHKRRISALGPGG
HHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
LSRDRAGFEVRDVHATHYGRLCPIETPEGPNIGLINSLASYARVNDYGFLEAPYRKVVDG
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCC
KVTDEIEYLSAIDEDNYVIAQASTKLDENNHFVEDIIQCRSGGEAIFTESSRVQYMDVSA
CCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEECCCCEEEEECCH
KQMVSAAAALIPFLEHDDANRVLMGANMQRQAVPTLKSEKPLVGTGMEKIVARDSGNCII
HHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHCCCCCCCCCCCCCCHHHHHCCCCCCEEE
ARNVGEVAEVDSNRIVIKVDTEKSQTSNLVDIYSLTKFKRSNKNTCINQRPIVNVGDKVE
EECCCCHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
AGDILADGFATDFGELSLGHNLMVAFMPWNGYNFEDSILLSERIVKDDKYTSIHIEEFTC
CCCEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEHEEE
VARDTKLGPEEITADIPNVSESSLAKLDESGIVHIGANVEAGDILVAKITPKAEQQLTPE
EECCCCCCHHHHHCCCCCCCHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCHHHCCCHH
ERLLRAIFNEKASNVVDSSLRMPSGTSGTVINVQVFENDKGGKSKRALKIEKELIDKARK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
DFDEEFAVIESVVKSSIEQEVVGAKIQKAKGLKKGAILTKEFLATLPLSKWLEISFEDEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHEEEEECHHH
LEEKVQNAREYYEEAKIAIDAKFEAKKKSITQSNELSPGVLKTVKVFVAIKKRIQPGDKM
HHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHH
AGRHGNKGVVSRVLPVEDMPYMEDGTPVDVCLNPLGIPSRMNIGQILEAHLGLASYGLGK
CCCCCCCCHHHHCCCCCCCCCCCCCCCHHHEECCCCCCCCCCHHHHHHHHHCHHHCCCCH
KIEKTLEKTRKAAELRKTLEEVYNSVGDKKVNLEALNDEEILTLCDNLKGGVPIATPVFD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCCCEECCCCC
GAKEEDIKSLLKIGGFATNGQMKLFDGRTGKPFDRHVTVGYMYMLKLDHLVDDKMHARST
CCCHHHHHHHHHHCCEECCCEEEEEECCCCCCCCCEEEEHHHEEHHHHHHHCCHHHHCCC
GSYSLVTQQPLGGKAQFGGQRFGEMEVWALQAYGAAYTLREMLTVKSDDIAGRSKMYKNI
CCEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCCCCHHHHHHHH
VDGKLTMNVDVPESFNVLRNEVRALGIDMDFDYSSEEE
CCCEEEEEECCCHHHHHHHHHHHHEECCCCCCCCCCCC
>Mature Secondary Structure 
SYSYAEKKRIRKEFGVLPHILDVPYLLSIQTESYKKFLTVDAAKGRLHSGLEIVLKQSF
CCCHHHHHHHHHHHCCCCHHHCCCEEEEEECHHCCEEEEEECCCCCHHCCHHEEEECCC
PVESKNGQYELHYVDYQIGEPTFDETECQVRGATYDAPLNVKLRLVVYNKDALPNEKIVE
CCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCEECCCCCEEEEEEEEECCCCCCHHHHH
DIREEYVYMGDIPLMTTNGTFIINGTERVVVSQLHRSPGAFFSKDDSEEGAFSARIIPYR
HHHHCEEEECCEEEEEECCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEC
GSWLDFEFDSKGIIWARIDRKRKFCATVILKALGYTQEQILENFSESKTITFNSKGFALR
CCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCEEE
LDNLSNMKGELLKFDIVDAQDNVIVKKNKKLTSRDVKKIKDAGVDSVAIDFDLVSTLRVA
ECCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
KDIVNEATGEVIAYANDDVTESLLKSCVEVGMLELEVIDFITTERGRYISDTLKYDLTRN
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCHHEEHHHHHHCCCCCEEHHHHHCCCCCC
TDEALVEIYKVLRPGDPPAAASVKALFEGLFFIESRYSLSDIGRMKLNARLGSDKVSKDI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCEEEECCCCCCHHHCCE
YTLENSDIVGVIEELINIRDGKGKVDDIDHLGNRRVRSVGEMVENQFRIGLYRVEKGIRE
EEECCCCHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMSLVHKDKLMPKDIVNSKPITAAIKEFFTSGALSQFMDQDNPLSEVTHKRRISALGPGG
HHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
LSRDRAGFEVRDVHATHYGRLCPIETPEGPNIGLINSLASYARVNDYGFLEAPYRKVVDG
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCC
KVTDEIEYLSAIDEDNYVIAQASTKLDENNHFVEDIIQCRSGGEAIFTESSRVQYMDVSA
CCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEECCCCEEEEECCH
KQMVSAAAALIPFLEHDDANRVLMGANMQRQAVPTLKSEKPLVGTGMEKIVARDSGNCII
HHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHCCCCCCCCCCCCCCHHHHHCCCCCCEEE
ARNVGEVAEVDSNRIVIKVDTEKSQTSNLVDIYSLTKFKRSNKNTCINQRPIVNVGDKVE
EECCCCHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
AGDILADGFATDFGELSLGHNLMVAFMPWNGYNFEDSILLSERIVKDDKYTSIHIEEFTC
CCCEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEHEEE
VARDTKLGPEEITADIPNVSESSLAKLDESGIVHIGANVEAGDILVAKITPKAEQQLTPE
EECCCCCCHHHHHCCCCCCCHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCHHHCCCHH
ERLLRAIFNEKASNVVDSSLRMPSGTSGTVINVQVFENDKGGKSKRALKIEKELIDKARK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
DFDEEFAVIESVVKSSIEQEVVGAKIQKAKGLKKGAILTKEFLATLPLSKWLEISFEDEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHEEEEECHHH
LEEKVQNAREYYEEAKIAIDAKFEAKKKSITQSNELSPGVLKTVKVFVAIKKRIQPGDKM
HHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHH
AGRHGNKGVVSRVLPVEDMPYMEDGTPVDVCLNPLGIPSRMNIGQILEAHLGLASYGLGK
CCCCCCCCHHHHCCCCCCCCCCCCCCCHHHEECCCCCCCCCCHHHHHHHHHCHHHCCCCH
KIEKTLEKTRKAAELRKTLEEVYNSVGDKKVNLEALNDEEILTLCDNLKGGVPIATPVFD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCCCEECCCCC
GAKEEDIKSLLKIGGFATNGQMKLFDGRTGKPFDRHVTVGYMYMLKLDHLVDDKMHARST
CCCHHHHHHHHHHCCEECCCEEEEEECCCCCCCCCEEEEHHHEEHHHHHHHCCHHHHCCC
GSYSLVTQQPLGGKAQFGGQRFGEMEVWALQAYGAAYTLREMLTVKSDDIAGRSKMYKNI
CCEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCCCCHHHHHHHH
VDGKLTMNVDVPESFNVLRNEVRALGIDMDFDYSSEEE
CCCEEEEEECCCHHHHHHHHHHHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA