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The map label for this gene is glnS [H]

Identifier: 89256894

GI number: 89256894

Start: 1546393

End: 1548039

Strand: Direct

Name: glnS [H]

Synonym: FTL_1617

Alternate gene names: 89256894

Gene position: 1546393-1548039 (Clockwise)

Preceding gene: 89256889

Following gene: 89256895

Centisome position: 81.56

GC content: 33.94

Gene sequence:

>1647_bases
ATGACTAGTGAAATTAAAGTAAATAAAACTAATTTTATAAAAAATATCATTAAGAAAGACCTCGAAACAAACAAAGTCTC
AAGTATTTTGACGCGTTTTCCTCCTGAGCCTAATGGTTATCTTCATATTGGCCATGCAAAATCAATATGTCTTAATTTTG
GTATTGCACAAGAATTTGATGGTAAGTGTAATCTACGCTTTGATGATACTAATCCTGATAAAGAAGACATTGAGTATATA
AACGCAATCCAAGAAGATGTCGAGTGGCTTGGTTTTAAATGGGAAAATCAACCACGTTTTGCCTCTGAATATTTTGATAA
GATGTATGAGCTAGCTATATTGCTTATAAAAAAAGGCAAAGCTTATGTCTGCGATTTGTCAGCAGAAGAAATACGCGCGT
ACCGTGGCACGCTAAAAGAGCCAGGAAAAAATAGTCCATACAGAGAACGCAGTATCACTGAAAACCTTGAATTATTTGAA
GAGATGAAAAATGGTAAATTTGCTGAAGGTAGTAAAACTTTGAGAGCAAAAATTGATATGTCTTCTGGTAATATCAACCT
TAGAGATCCTGCCTTATACAGAATAAAATTCTCACACCACCCTAAAACTGGTGACAAATGGTGTATTTATCCGATGTATA
CATTTGCTCATCCACTTGAGGATGCAATCGAAAAAATAACTCATTCGTTATGTACTTTGGAATTCCAAGATCAAAGACCA
TTCTATGACTGGGTTATTGAGGAAACAGAATTTAGTATAAAACCACAGCAAATTGAATTTTCAAGACTTAATCTTAATTA
CACAATTACAAGTAAGCGAAAACTAAAATATTTGGTTGATAATAAACTTGTCAATGGCTGGGATGACCCACGTATGCCAA
CTATAAAAGGCTATCGCCGTAGAGGTTATACCCCTGAGTCTATACGCAATTTCTGTGAGATGATAGGAATATCTAAACAA
GATTCTGTTATTGACGTATCGGTTTTAGAAGATGCTATAAGAGATGATTTAAACAAAAGTGTCTTAAGAAAAAACGTTGT
CCTAGATCCAATAAGAGTAAGCATAAAAGATATGCCAAATCATCATTTAGATGTACCAAACCACCCACAAGATCCAGAAT
TTGGACGCCGCGAGATCACAATATCTTCACAAATATTCATTGAAAGAGATGACTTTGTCTTCAAGCTAGAAAAAGATATG
AAAAAACTTAGTCCTAATGGTAGAGTGCGTTTACTAAATAGCTATGTAATTGAGTGTCAAGAAGTAATTACTGATACTAG
TGGCGAAGTCATAGAACTAAAATGCTCTTATCTACCAGAAACTTTAGGTGGTAAAAAACCAAATGATGGTATCAAGCCTA
ATGGCATTATCCATTGGGTTGATGCTAATAATTGCCTTGATGCTGAAGTTAGGATTTATGATCGCTTATTTAATGATGAA
AATCCAGCAAATGCTGATCGAATTGAAGATGTTTTAAATCCAGACTCATTACAAGTTATTAAAAATGCCAAAGTTGAAAG
ATCTCTTGAAAGTGTCAAAGCTGAAGAACGCTTTCAGTTTAACAGAGTTGGTTATTTTATTGCTGACTTAAAAGATTGCT
CTAACGACACATTAGTATTTAATCGTATTGCAACTCTTAGAAACTGA

Upstream 100 bases:

>100_bases
TAGCTAGTATATACTTTTTTTTCAAAAAAATATGTTATTGTTTTTTTATTAAAGTAAACTATTAAATAAAATTTATTTAA
GAACTATTTCTAAGACAAAA

Downstream 100 bases:

>100_bases
TTCAAAGGTAATACATTATAATGTTATCAAACTCAAAGAAAACTATTATATGTGGTTTTTCTTTTTTTTGTATCTGGATA
TTTGGAACTCTAGCCTTATA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MTSEIKVNKTNFIKNIIKKDLETNKVSSILTRFPPEPNGYLHIGHAKSICLNFGIAQEFDGKCNLRFDDTNPDKEDIEYI
NAIQEDVEWLGFKWENQPRFASEYFDKMYELAILLIKKGKAYVCDLSAEEIRAYRGTLKEPGKNSPYRERSITENLELFE
EMKNGKFAEGSKTLRAKIDMSSGNINLRDPALYRIKFSHHPKTGDKWCIYPMYTFAHPLEDAIEKITHSLCTLEFQDQRP
FYDWVIEETEFSIKPQQIEFSRLNLNYTITSKRKLKYLVDNKLVNGWDDPRMPTIKGYRRRGYTPESIRNFCEMIGISKQ
DSVIDVSVLEDAIRDDLNKSVLRKNVVLDPIRVSIKDMPNHHLDVPNHPQDPEFGRREITISSQIFIERDDFVFKLEKDM
KKLSPNGRVRLLNSYVIECQEVITDTSGEVIELKCSYLPETLGGKKPNDGIKPNGIIHWVDANNCLDAEVRIYDRLFNDE
NPANADRIEDVLNPDSLQVIKNAKVERSLESVKAEERFQFNRVGYFIADLKDCSNDTLVFNRIATLRN

Sequences:

>Translated_548_residues
MTSEIKVNKTNFIKNIIKKDLETNKVSSILTRFPPEPNGYLHIGHAKSICLNFGIAQEFDGKCNLRFDDTNPDKEDIEYI
NAIQEDVEWLGFKWENQPRFASEYFDKMYELAILLIKKGKAYVCDLSAEEIRAYRGTLKEPGKNSPYRERSITENLELFE
EMKNGKFAEGSKTLRAKIDMSSGNINLRDPALYRIKFSHHPKTGDKWCIYPMYTFAHPLEDAIEKITHSLCTLEFQDQRP
FYDWVIEETEFSIKPQQIEFSRLNLNYTITSKRKLKYLVDNKLVNGWDDPRMPTIKGYRRRGYTPESIRNFCEMIGISKQ
DSVIDVSVLEDAIRDDLNKSVLRKNVVLDPIRVSIKDMPNHHLDVPNHPQDPEFGRREITISSQIFIERDDFVFKLEKDM
KKLSPNGRVRLLNSYVIECQEVITDTSGEVIELKCSYLPETLGGKKPNDGIKPNGIIHWVDANNCLDAEVRIYDRLFNDE
NPANADRIEDVLNPDSLQVIKNAKVERSLESVKAEERFQFNRVGYFIADLKDCSNDTLVFNRIATLRN
>Mature_547_residues
TSEIKVNKTNFIKNIIKKDLETNKVSSILTRFPPEPNGYLHIGHAKSICLNFGIAQEFDGKCNLRFDDTNPDKEDIEYIN
AIQEDVEWLGFKWENQPRFASEYFDKMYELAILLIKKGKAYVCDLSAEEIRAYRGTLKEPGKNSPYRERSITENLELFEE
MKNGKFAEGSKTLRAKIDMSSGNINLRDPALYRIKFSHHPKTGDKWCIYPMYTFAHPLEDAIEKITHSLCTLEFQDQRPF
YDWVIEETEFSIKPQQIEFSRLNLNYTITSKRKLKYLVDNKLVNGWDDPRMPTIKGYRRRGYTPESIRNFCEMIGISKQD
SVIDVSVLEDAIRDDLNKSVLRKNVVLDPIRVSIKDMPNHHLDVPNHPQDPEFGRREITISSQIFIERDDFVFKLEKDMK
KLSPNGRVRLLNSYVIECQEVITDTSGEVIELKCSYLPETLGGKKPNDGIKPNGIIHWVDANNCLDAEVRIYDRLFNDEN
PANADRIEDVLNPDSLQVIKNAKVERSLESVKAEERFQFNRVGYFIADLKDCSNDTLVFNRIATLRN

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=548, Percent_Identity=42.3357664233577, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI62241042, Length=380, Percent_Identity=41.3157894736842, Blast_Score=272, Evalue=7e-73,
Organism=Escherichia coli, GI1786895, Length=548, Percent_Identity=54.5620437956204, Blast_Score=618, Evalue=1e-178,
Organism=Escherichia coli, GI1788743, Length=310, Percent_Identity=26.1290322580645, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17543332, Length=531, Percent_Identity=41.9962335216573, Blast_Score=410, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17511007, Length=514, Percent_Identity=30.3501945525292, Blast_Score=229, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6324742, Length=576, Percent_Identity=38.7152777777778, Blast_Score=383, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6321192, Length=524, Percent_Identity=34.3511450381679, Blast_Score=280, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6324540, Length=310, Percent_Identity=25.4838709677419, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17864488, Length=528, Percent_Identity=42.6136363636364, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24649466, Length=430, Percent_Identity=37.2093023255814, Blast_Score=254, Evalue=1e-67,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 63595; Mature: 63464

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSEIKVNKTNFIKNIIKKDLETNKVSSILTRFPPEPNGYLHIGHAKSICLNFGIAQEFD
CCCCEECCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECCHHEEHEECCCCCCCC
GKCNLRFDDTNPDKEDIEYINAIQEDVEWLGFKWENQPRFASEYFDKMYELAILLIKKGK
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHEECCC
AYVCDLSAEEIRAYRGTLKEPGKNSPYRERSITENLELFEEMKNGKFAEGSKTLRAKIDM
EEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEE
SSGNINLRDPALYRIKFSHHPKTGDKWCIYPMYTFAHPLEDAIEKITHSLCTLEFQDQRP
CCCCEEECCCEEEEEEECCCCCCCCCEEEEEHHHHHCHHHHHHHHHHHHHEEEEECCCCC
FYDWVIEETEFSIKPQQIEFSRLNLNYTITSKRKLKYLVDNKLVNGWDDPRMPTIKGYRR
HHHHEEECCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHCCCCCCCCCCCCCCCHHHHHH
RGYTPESIRNFCEMIGISKQDSVIDVSVLEDAIRDDLNKSVLRKNVVLDPIRVSIKDMPN
CCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCEECCCEEEEECCCC
HHLDVPNHPQDPEFGRREITISSQIFIERDDFVFKLEKDMKKLSPNGRVRLLNSYVIECQ
CCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEHHHHHHCCCCCCEEEHHHHHHHHH
EVITDTSGEVIELKCSYLPETLGGKKPNDGIKPNGIIHWVDANNCLDAEVRIYDRLFNDE
HHHCCCCCCEEEEEECCCCHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCC
NPANADRIEDVLNPDSLQVIKNAKVERSLESVKAEERFQFNRVGYFIADLKDCSNDTLVF
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCCEEE
NRIATLRN
HHHHHHCC
>Mature Secondary Structure 
TSEIKVNKTNFIKNIIKKDLETNKVSSILTRFPPEPNGYLHIGHAKSICLNFGIAQEFD
CCCEECCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECCHHEEHEECCCCCCCC
GKCNLRFDDTNPDKEDIEYINAIQEDVEWLGFKWENQPRFASEYFDKMYELAILLIKKGK
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHEECCC
AYVCDLSAEEIRAYRGTLKEPGKNSPYRERSITENLELFEEMKNGKFAEGSKTLRAKIDM
EEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEE
SSGNINLRDPALYRIKFSHHPKTGDKWCIYPMYTFAHPLEDAIEKITHSLCTLEFQDQRP
CCCCEEECCCEEEEEEECCCCCCCCCEEEEEHHHHHCHHHHHHHHHHHHHEEEEECCCCC
FYDWVIEETEFSIKPQQIEFSRLNLNYTITSKRKLKYLVDNKLVNGWDDPRMPTIKGYRR
HHHHEEECCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHCCCCCCCCCCCCCCCHHHHHH
RGYTPESIRNFCEMIGISKQDSVIDVSVLEDAIRDDLNKSVLRKNVVLDPIRVSIKDMPN
CCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCEECCCEEEEECCCC
HHLDVPNHPQDPEFGRREITISSQIFIERDDFVFKLEKDMKKLSPNGRVRLLNSYVIECQ
CCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEHHHHHHCCCCCCEEEHHHHHHHHH
EVITDTSGEVIELKCSYLPETLGGKKPNDGIKPNGIIHWVDANNCLDAEVRIYDRLFNDE
HHHCCCCCCEEEEEECCCCHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCC
NPANADRIEDVLNPDSLQVIKNAKVERSLESVKAEERFQFNRVGYFIADLKDCSNDTLVF
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCCEEE
NRIATLRN
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]