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The map label for this gene is xasA [C]

Identifier: 89256860

GI number: 89256860

Start: 1510246

End: 1511655

Strand: Direct

Name: xasA [C]

Synonym: FTL_1583

Alternate gene names: 89256860

Gene position: 1510246-1511655 (Clockwise)

Preceding gene: 89256858

Following gene: 89256861

Centisome position: 79.65

GC content: 33.4

Gene sequence:

>1410_bases
ATGGAACAAATTATTAGTAGTAAAAAATTTGGTCTTATCAGACTAATAATGATAAATATTATCGCTGTCGATAGCTTAAG
AAATATCTCTATAACGGCTCAAGCAGGTTGGATCGTTATAACTTTCTATATTTTAGCTGGAATTTTCTTCTTGACTCCGT
GTGCGCTACTAACCGCAGAAATGTCTACCGGCTCCTCACAAGAGAATGGTGGTATCTATATCTGGGTTAAAAAAGCATTT
GGCAAAAGACTAGGATTTTTGGTTATCTGGTTACAGTGGGTTTACAACTTAGTTTGGTTTCCATCTATTTGTGGATTCTT
CGCTGGAGTTATTGCTTATGTCATAGCACCTTTGACCGGACAAGATGCTAATCACTTAGTTGCTAATCCTTGGTATATGA
TATCAATGAGTTTAGTAATGTTTTGGAGTGCCACCGCAATTAACTTATTTGGTATCAAAACATCAAGTACTGTAAGTACA
CTTGGAGCTATTATTGGTACACTTTTACCAATATTTATTATCATAATAATAGCAATAATATGGTCGATGTCTCATACTGC
TGAAATTGTTGCGCCAAAAATTTCTGATTTTATTCCATCGGGTAATAATATCAGTAGCTGGGCTTTATTTATAACTGTGA
TGTTTAGCCTTTTCGGTTTAGAAATGAGTGCTATACATGCAGCAAATGTCAAAAATGCTAAGAAAAATTTTCCTCGTGCC
CTCCTAATTTCAGGTTCTGTAATATTAGGATCTTTGATTTTATCAAATATTGCGGTGATATTAGTAAGTAGCCAGTTACA
GATTGGTGATGTTGATATAGTTACAGGTCTAATGGTTTCTTTCCACTACTTCTTTAGTCAGATTAATATGCCATGGATGA
CTTATATAATCGCAGTAACGCTGATATTTGGTGCATTTACAACAACATCAGCTTGGATTATGGGATTATCTAGAGCTTTT
ATGGTTGTTAGTAATGACAACATCTTGCCACAAATATTTGGTAGGACAAATAAAAATGATGCTCCTGATACTATGCTTAT
TACCCAAGCACTTGTTTTTACAGTATTTTGCTTCTCATATATATTTATGCCATCAGTAAATGAAGCATATTGGTATCTTA
GTGATTTAACTGCACAGTTAGCGGTTATAGCATATATCTTGATGTTTATTACGGCTGTAAAACTAAAAATTAGCTCACCA
CTTGAAGAAGATCAATATGAAATATGTAAGGGTTCTTTTGGAACTATTCTAATGGCATTACTAGGTTGTTTTGGCTGTTT
AGTAGCGATAATTGTCGGATTTATTCCTATAGACAATATGGCAATGTCAGTTTTTAATTTTGACATGATGCTTATTGTAG
GAATTGTTATTACACTAATTATTCCAGCAGTTATAACCATTAAAAAATAA

Upstream 100 bases:

>100_bases
AAAACCTTTCGTTTCATAAAAGTAACACACGCTCTAGTTGTTATAAAATTCCTTTAAGTATATACTAAAGCGTGGTATTG
AAGAAATAAAAAGTAAAATA

Downstream 100 bases:

>100_bases
ATCTTAATTATCTCTAAAAACTTTGACACTCTAAAAATATTCAAATATTGTGTAAAACTGTTACAATATCAACACTTTAA
TTAATAATTTTTTTATATTA

Product: glutamate:gamma-aminobutyric acid antiporter family protein

Products: L-glutamate [Cytoplasm]; 4-aminobutyrate [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MEQIISSKKFGLIRLIMINIIAVDSLRNISITAQAGWIVITFYILAGIFFLTPCALLTAEMSTGSSQENGGIYIWVKKAF
GKRLGFLVIWLQWVYNLVWFPSICGFFAGVIAYVIAPLTGQDANHLVANPWYMISMSLVMFWSATAINLFGIKTSSTVST
LGAIIGTLLPIFIIIIIAIIWSMSHTAEIVAPKISDFIPSGNNISSWALFITVMFSLFGLEMSAIHAANVKNAKKNFPRA
LLISGSVILGSLILSNIAVILVSSQLQIGDVDIVTGLMVSFHYFFSQINMPWMTYIIAVTLIFGAFTTTSAWIMGLSRAF
MVVSNDNILPQIFGRTNKNDAPDTMLITQALVFTVFCFSYIFMPSVNEAYWYLSDLTAQLAVIAYILMFITAVKLKISSP
LEEDQYEICKGSFGTILMALLGCFGCLVAIIVGFIPIDNMAMSVFNFDMMLIVGIVITLIIPAVITIKK

Sequences:

>Translated_469_residues
MEQIISSKKFGLIRLIMINIIAVDSLRNISITAQAGWIVITFYILAGIFFLTPCALLTAEMSTGSSQENGGIYIWVKKAF
GKRLGFLVIWLQWVYNLVWFPSICGFFAGVIAYVIAPLTGQDANHLVANPWYMISMSLVMFWSATAINLFGIKTSSTVST
LGAIIGTLLPIFIIIIIAIIWSMSHTAEIVAPKISDFIPSGNNISSWALFITVMFSLFGLEMSAIHAANVKNAKKNFPRA
LLISGSVILGSLILSNIAVILVSSQLQIGDVDIVTGLMVSFHYFFSQINMPWMTYIIAVTLIFGAFTTTSAWIMGLSRAF
MVVSNDNILPQIFGRTNKNDAPDTMLITQALVFTVFCFSYIFMPSVNEAYWYLSDLTAQLAVIAYILMFITAVKLKISSP
LEEDQYEICKGSFGTILMALLGCFGCLVAIIVGFIPIDNMAMSVFNFDMMLIVGIVITLIIPAVITIKK
>Mature_469_residues
MEQIISSKKFGLIRLIMINIIAVDSLRNISITAQAGWIVITFYILAGIFFLTPCALLTAEMSTGSSQENGGIYIWVKKAF
GKRLGFLVIWLQWVYNLVWFPSICGFFAGVIAYVIAPLTGQDANHLVANPWYMISMSLVMFWSATAINLFGIKTSSTVST
LGAIIGTLLPIFIIIIIAIIWSMSHTAEIVAPKISDFIPSGNNISSWALFITVMFSLFGLEMSAIHAANVKNAKKNFPRA
LLISGSVILGSLILSNIAVILVSSQLQIGDVDIVTGLMVSFHYFFSQINMPWMTYIIAVTLIFGAFTTTSAWIMGLSRAF
MVVSNDNILPQIFGRTNKNDAPDTMLITQALVFTVFCFSYIFMPSVNEAYWYLSDLTAQLAVIAYILMFITAVKLKISSP
LEEDQYEICKGSFGTILMALLGCFGCLVAIIVGFIPIDNMAMSVFNFDMMLIVGIVITLIIPAVITIKK

Specific function: Probable Amino Acid Transporter. Involved In Extreme Acid Resistance. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787768, Length=442, Percent_Identity=24.6606334841629, Blast_Score=159, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51612; Mature: 51612

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQIISSKKFGLIRLIMINIIAVDSLRNISITAQAGWIVITFYILAGIFFLTPCALLTAE
CCCHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
MSTGSSQENGGIYIWVKKAFGKRLGFLVIWLQWVYNLVWFPSICGFFAGVIAYVIAPLTG
HCCCCCCCCCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QDANHLVANPWYMISMSLVMFWSATAINLFGIKTSSTVSTLGAIIGTLLPIFIIIIIAII
CCCCCEECCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WSMSHTAEIVAPKISDFIPSGNNISSWALFITVMFSLFGLEMSAIHAANVKNAKKNFPRA
HCCCCHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHCCCCE
LLISGSVILGSLILSNIAVILVSSQLQIGDVDIVTGLMVSFHYFFSQINMPWMTYIIAVT
EEEECHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LIFGAFTTTSAWIMGLSRAFMVVSNDNILPQIFGRTNKNDAPDTMLITQALVFTVFCFSY
HHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
IFMPSVNEAYWYLSDLTAQLAVIAYILMFITAVKLKISSPLEEDQYEICKGSFGTILMAL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHH
LGCFGCLVAIIVGFIPIDNMAMSVFNFDMMLIVGIVITLIIPAVITIKK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEQIISSKKFGLIRLIMINIIAVDSLRNISITAQAGWIVITFYILAGIFFLTPCALLTAE
CCCHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
MSTGSSQENGGIYIWVKKAFGKRLGFLVIWLQWVYNLVWFPSICGFFAGVIAYVIAPLTG
HCCCCCCCCCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QDANHLVANPWYMISMSLVMFWSATAINLFGIKTSSTVSTLGAIIGTLLPIFIIIIIAII
CCCCCEECCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WSMSHTAEIVAPKISDFIPSGNNISSWALFITVMFSLFGLEMSAIHAANVKNAKKNFPRA
HCCCCHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHCCCCE
LLISGSVILGSLILSNIAVILVSSQLQIGDVDIVTGLMVSFHYFFSQINMPWMTYIIAVT
EEEECHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LIFGAFTTTSAWIMGLSRAFMVVSNDNILPQIFGRTNKNDAPDTMLITQALVFTVFCFSY
HHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
IFMPSVNEAYWYLSDLTAQLAVIAYILMFITAVKLKISSPLEEDQYEICKGSFGTILMAL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHH
LGCFGCLVAIIVGFIPIDNMAMSVFNFDMMLIVGIVITLIIPAVITIKK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-aminobutyrate [Cytoplasm]; L-glutamate [Periplasm] [C]

Specific reaction: 4-aminobutyrate [Cytoplasm] + L-glutamate [Periplasm] = L-glutamate [Cytoplasm] + 4-aminobutyrate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8366052 [H]