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The map label for this gene is pqqL [C]

Identifier: 89256771

GI number: 89256771

Start: 1408503

End: 1409756

Strand: Direct

Name: pqqL [C]

Synonym: FTL_1482

Alternate gene names: 89256771

Gene position: 1408503-1409756 (Clockwise)

Preceding gene: 89256770

Following gene: 89256772

Centisome position: 74.29

GC content: 31.74

Gene sequence:

>1254_bases
ATGAGTATCGAAAAATATTCCCTAAATAATAATTTAGATATCTATATAAAAAAAGATATACGAGCACCTGTGGTTTTGGC
ACAAATATGGTATAAAGTTGGCTCAACATACGAGCCTGAAAAACTTACTGGCATATCTCATATGCTTGAACATATGATGT
TTAAAGGTACAAACAAATATTCAAAAGATGAGTTAAATAGCATAGTTGAAAATAATGGCGGTATCCAAAATGCTTTCACA
AGCTTTGACTACACTGCATATTACCAGTTTTGGCATAGGAAAAATCTCGAATTAAGCTTATCTATAGAATCATCACGAAT
GAGTGATTTATTGTTTGATGAAAATGAGTTTATGCCAGAAAAGAAGGTAGTTTTAGAAGAGAGAAGCTTACGGGTTGATG
ATAAAGCTTTTAGTTATGCTTTTGAACAATTTATGCAACTTGCGTATCAAAAAAACTCGCGTCACACTCCTGTTATTGGC
TGGCGTGAAGACATTAAAAACTATACTCTTGATAATCTCAAAAAATGGTATCAACAAAATTATGCTCCAAATAATTCAAG
TATTGTTTTAGTTGGAGACATTGATACAGCTTCAGCATTATCAATGGCTAAGGATTATTTTGCTAGTATCCCAAAATCTC
AACTAATTGCTACAAAAAAAGAGTCTAGCTTAATTAATATTGGTCATAGACATTTAAAAGTAAAAAAATCACCAAATGAT
ACTGCCGCATTAATATTAGGATATATCACACCTTCTCTAACCACAGATTATAAAGATAATGATCCGTTTGCCCTACTAGT
TCTTAATAATATCCTTGGTAATGCTAATGCATCAATACTGCAACAACAGCTAGTAAGAGAAGAAAATCTATGTTGTCATA
TCGATAGTGAGTATTCACCATTTATAAAAGGTGAAGATATTTTCACAATTACAGCTATAGCAAATCATGATCAAGAGCTA
GATGGTATCGAAGACAAAATACAAGGTATTATAGCTAAGCTTAGGAATAAAGGTATTACTACAGAGCAGCTTAATCGAGC
AAAAGTAACTATCAAAGCTGATAAAGTATTTGCCATGGATTCACTCGAAACTCAAGCAAATCTGATAGGTTCTTTAGCTA
GTATTAACCTAGATGTTGACTACTATAAATACCTTGAGAAACTTTATGATGTAACAGTTAGTGACATTAATCGTGTACTT
GATAGATATTTTGATAAACAAAACCTTGCATCTCTACATTTATTAAGGGATTAA

Upstream 100 bases:

>100_bases
TTACACTTACCACCAATACTTGGTGCTGCAGGGCCAACTGTTATAGCGCTAATATTGTTAATATATTTATTTATAAAATC
AAAAGAAACATAAAAATAAC

Downstream 100 bases:

>100_bases
AAAATCATGATCTATAAATTTAATATTGATAATACACCCATATACTTTCAAGAATCCCACAACTTACCAATGTTAGATAT
TCAACTTAATTTCAGAGCTG

Product: peptidase M16 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSIEKYSLNNNLDIYIKKDIRAPVVLAQIWYKVGSTYEPEKLTGISHMLEHMMFKGTNKYSKDELNSIVENNGGIQNAFT
SFDYTAYYQFWHRKNLELSLSIESSRMSDLLFDENEFMPEKKVVLEERSLRVDDKAFSYAFEQFMQLAYQKNSRHTPVIG
WREDIKNYTLDNLKKWYQQNYAPNNSSIVLVGDIDTASALSMAKDYFASIPKSQLIATKKESSLINIGHRHLKVKKSPND
TAALILGYITPSLTTDYKDNDPFALLVLNNILGNANASILQQQLVREENLCCHIDSEYSPFIKGEDIFTITAIANHDQEL
DGIEDKIQGIIAKLRNKGITTEQLNRAKVTIKADKVFAMDSLETQANLIGSLASINLDVDYYKYLEKLYDVTVSDINRVL
DRYFDKQNLASLHLLRD

Sequences:

>Translated_417_residues
MSIEKYSLNNNLDIYIKKDIRAPVVLAQIWYKVGSTYEPEKLTGISHMLEHMMFKGTNKYSKDELNSIVENNGGIQNAFT
SFDYTAYYQFWHRKNLELSLSIESSRMSDLLFDENEFMPEKKVVLEERSLRVDDKAFSYAFEQFMQLAYQKNSRHTPVIG
WREDIKNYTLDNLKKWYQQNYAPNNSSIVLVGDIDTASALSMAKDYFASIPKSQLIATKKESSLINIGHRHLKVKKSPND
TAALILGYITPSLTTDYKDNDPFALLVLNNILGNANASILQQQLVREENLCCHIDSEYSPFIKGEDIFTITAIANHDQEL
DGIEDKIQGIIAKLRNKGITTEQLNRAKVTIKADKVFAMDSLETQANLIGSLASINLDVDYYKYLEKLYDVTVSDINRVL
DRYFDKQNLASLHLLRD
>Mature_416_residues
SIEKYSLNNNLDIYIKKDIRAPVVLAQIWYKVGSTYEPEKLTGISHMLEHMMFKGTNKYSKDELNSIVENNGGIQNAFTS
FDYTAYYQFWHRKNLELSLSIESSRMSDLLFDENEFMPEKKVVLEERSLRVDDKAFSYAFEQFMQLAYQKNSRHTPVIGW
REDIKNYTLDNLKKWYQQNYAPNNSSIVLVGDIDTASALSMAKDYFASIPKSQLIATKKESSLINIGHRHLKVKKSPNDT
AALILGYITPSLTTDYKDNDPFALLVLNNILGNANASILQQQLVREENLCCHIDSEYSPFIKGEDIFTITAIANHDQELD
GIEDKIQGIIAKLRNKGITTEQLNRAKVTIKADKVFAMDSLETQANLIGSLASINLDVDYYKYLEKLYDVTVSDINRVLD
RYFDKQNLASLHLLRD

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=279, Percent_Identity=28.3154121863799, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI46593007, Length=207, Percent_Identity=24.1545893719807, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1787770, Length=192, Percent_Identity=30.7291666666667, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71999683, Length=249, Percent_Identity=24.4979919678715, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17553678, Length=207, Percent_Identity=25.1207729468599, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=348, Percent_Identity=23.5632183908046, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357875, Length=409, Percent_Identity=22.9828850855746, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646943, Length=409, Percent_Identity=22.9828850855746, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47816; Mature: 47685

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEKYSLNNNLDIYIKKDIRAPVVLAQIWYKVGSTYEPEKLTGISHMLEHMMFKGTNKY
CCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
SKDELNSIVENNGGIQNAFTSFDYTAYYQFWHRKNLELSLSIESSRMSDLLFDENEFMPE
CHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCCCH
KKVVLEERSLRVDDKAFSYAFEQFMQLAYQKNSRHTPVIGWREDIKNYTLDNLKKWYQQN
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHCCCHHHHHHHHHHC
YAPNNSSIVLVGDIDTASALSMAKDYFASIPKSQLIATKKESSLINIGHRHLKVKKSPND
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHEEECCCCCCEECCCEEEEEECCCCC
TAALILGYITPSLTTDYKDNDPFALLVLNNILGNANASILQQQLVREENLCCHIDSEYSP
CCEEEEEECCCCCCCCCCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCC
FIKGEDIFTITAIANHDQELDGIEDKIQGIIAKLRNKGITTEQLNRAKVTIKADKVFAMD
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEEEEECCEEEHH
SLETQANLIGSLASINLDVDYYKYLEKLYDVTVSDINRVLDRYFDKQNLASLHLLRD
HHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHEEECC
>Mature Secondary Structure 
SIEKYSLNNNLDIYIKKDIRAPVVLAQIWYKVGSTYEPEKLTGISHMLEHMMFKGTNKY
CCCEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
SKDELNSIVENNGGIQNAFTSFDYTAYYQFWHRKNLELSLSIESSRMSDLLFDENEFMPE
CHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCCCH
KKVVLEERSLRVDDKAFSYAFEQFMQLAYQKNSRHTPVIGWREDIKNYTLDNLKKWYQQN
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHCCCHHHHHHHHHHC
YAPNNSSIVLVGDIDTASALSMAKDYFASIPKSQLIATKKESSLINIGHRHLKVKKSPND
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHEEECCCCCCEECCCEEEEEECCCCC
TAALILGYITPSLTTDYKDNDPFALLVLNNILGNANASILQQQLVREENLCCHIDSEYSP
CCEEEEEECCCCCCCCCCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCC
FIKGEDIFTITAIANHDQELDGIEDKIQGIIAKLRNKGITTEQLNRAKVTIKADKVFAMD
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEEEEECCEEEHH
SLETQANLIGSLASINLDVDYYKYLEKLYDVTVSDINRVLDRYFDKQNLASLHLLRD
HHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]