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The map label for this gene is pgm [H]

Identifier: 89255894

GI number: 89255894

Start: 465981

End: 467615

Strand: Direct

Name: pgm [H]

Synonym: FTL_0484

Alternate gene names: 89255894

Gene position: 465981-467615 (Clockwise)

Preceding gene: 89255890

Following gene: 89255895

Centisome position: 24.58

GC content: 35.84

Gene sequence:

>1635_bases
ATGGCGATTCAAACTGTATCAACTAAACCTTTTGCTAATCAAAAACCAGGTACATCTGGATTACGAAATAAAGTCATAGC
TTTTCAACAGCCCAGATATTTGGAGAACTTTGTACAATCTATATTTAACTCATTGGATGATATAGAAGGTAAAACTTTAG
TTGTTGGTGGTGATGGTAGATATTACAATGATGTTGCAATACAAATTATCGTCAGAATGGCAGCAGCTAATGGTTTTGCT
AAGATAATAGTTGGTCAAAATGGTATATTTTCTACTCCAGCTGTTAGTTGTGTTATCCGAAAATATGAGGCTTTTGGTGG
GATTGTATTATCGGCAAGTCATAATCCGGGTGGTCCAAAAGGAGACTTTGGTATCAAATATAATGTTTCTAATGGTGGTC
CAGCTCCTGAAAAAATTACAGATAGAATTTTTTCTGAAACAAAAAAAATTAATCAATACTTTATAAGTGATGCAGCTAAG
GAAAGGGTTGATCTAGACAAGTTAGGCATATACAAGATTGAGAATACAACTGTCGAGGTTATCAATTCGGTAATTGATTA
TGCTGAGTTGATGCAACAGATTTTTGATTTTGATAAGGTTCGCGAATTATTTGCTAAAGGATTTAAAGTACGTTTTGATT
CTATGTGTGCGGTGTCTGGTCCTTATGCAAAATATATTTTTGAAACTCTTTTGAAAGCTCCAGCAGGCACAGTTGTAAAT
GCTCAGCCACTTGAGGATTTTGGAGGGTTTCATCCAGATCCAAATCCTGTAAATGCTGAAGATTTAGTCAAGCATATGCG
TAGTGGTAAGTATGATTTCGGCGCAGCTTCAGATGGTGATGCTGATAGAAATATGATTGTTGGTAAACAAATATATGTAT
CTCCTTCAGATAGCCTAGCAATTATGGCTGCAAATGCGCATCTTATACCAGTGTATTCAAAAGGAATTAAAGGTGTTGCT
AGATCGATGCCTACATCAACAGCGGTTGATAGAGTTGCAGAGTCATTACGACTATCTTGTTTCGAGACTCCAACAGGATG
GAAATTCTTTGGTAATTTACTAGATGCTGAAAAAATCACACTATGTGGCGAAGAGAGTTATGGTACCGGCTCTAACCATA
TTCGTGAGAAAGATGGCGTTTGGGCTGTGCTGTTTTGGTTAAATTTAGTTGCAGTTACAGGCAAACAAGTTGATCAACTT
GTTGAAGAACATTGGCAAAAATTTGGGCGTAACTTCTATTCAAGACATGACTATGAGGCTATAGATACTGCGATTGCTAA
CTCTATTATAGACTCTTTAAGAGAAAGGTTGTCTAGTCTAGTAGGAGCTCAGTTGAATGATGAGAAAGTCGCTAAAGCAG
ATGATTTTAGTTATATAGATCCAATAGATGGTTCAGTTTCTAATCATCAAGGAATAAGAATTATTTTTGAAGATGGTTCA
CGTATTGTGTTTAGGTTATCTGGTACAGGAACACAAGGTGCTACTTTACGTATATATTTAGAAAAATATGAGTCAGATTC
TTCTAAGTTTAGTATACCGACACAACAAGCTCTAGCTAGCTTGATAGAGATTGCTGAAGATTTGACCAATATTAAATCTT
TAACAGGAATGACTGAACCAACTATAGTTACTTAA

Upstream 100 bases:

>100_bases
GATAAGATGAATGATATGGGCTTTTAACCAATAAGCCACCTAACATCGACTAGGCTCACTATTTGGGTGTATGTTAATCA
ATAAATACTAGGGTAAAAAA

Downstream 100 bases:

>100_bases
CTAAAATTTTTTTAACACAAAGGAGCTTATGATATGGATAATCATAATTCATCACATCAGTTGTACAAAAAAGCTATGGC
ATTAGTTTTAGCTGGAGGAC

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MAIQTVSTKPFANQKPGTSGLRNKVIAFQQPRYLENFVQSIFNSLDDIEGKTLVVGGDGRYYNDVAIQIIVRMAAANGFA
KIIVGQNGIFSTPAVSCVIRKYEAFGGIVLSASHNPGGPKGDFGIKYNVSNGGPAPEKITDRIFSETKKINQYFISDAAK
ERVDLDKLGIYKIENTTVEVINSVIDYAELMQQIFDFDKVRELFAKGFKVRFDSMCAVSGPYAKYIFETLLKAPAGTVVN
AQPLEDFGGFHPDPNPVNAEDLVKHMRSGKYDFGAASDGDADRNMIVGKQIYVSPSDSLAIMAANAHLIPVYSKGIKGVA
RSMPTSTAVDRVAESLRLSCFETPTGWKFFGNLLDAEKITLCGEESYGTGSNHIREKDGVWAVLFWLNLVAVTGKQVDQL
VEEHWQKFGRNFYSRHDYEAIDTAIANSIIDSLRERLSSLVGAQLNDEKVAKADDFSYIDPIDGSVSNHQGIRIIFEDGS
RIVFRLSGTGTQGATLRIYLEKYESDSSKFSIPTQQALASLIEIAEDLTNIKSLTGMTEPTIVT

Sequences:

>Translated_544_residues
MAIQTVSTKPFANQKPGTSGLRNKVIAFQQPRYLENFVQSIFNSLDDIEGKTLVVGGDGRYYNDVAIQIIVRMAAANGFA
KIIVGQNGIFSTPAVSCVIRKYEAFGGIVLSASHNPGGPKGDFGIKYNVSNGGPAPEKITDRIFSETKKINQYFISDAAK
ERVDLDKLGIYKIENTTVEVINSVIDYAELMQQIFDFDKVRELFAKGFKVRFDSMCAVSGPYAKYIFETLLKAPAGTVVN
AQPLEDFGGFHPDPNPVNAEDLVKHMRSGKYDFGAASDGDADRNMIVGKQIYVSPSDSLAIMAANAHLIPVYSKGIKGVA
RSMPTSTAVDRVAESLRLSCFETPTGWKFFGNLLDAEKITLCGEESYGTGSNHIREKDGVWAVLFWLNLVAVTGKQVDQL
VEEHWQKFGRNFYSRHDYEAIDTAIANSIIDSLRERLSSLVGAQLNDEKVAKADDFSYIDPIDGSVSNHQGIRIIFEDGS
RIVFRLSGTGTQGATLRIYLEKYESDSSKFSIPTQQALASLIEIAEDLTNIKSLTGMTEPTIVT
>Mature_543_residues
AIQTVSTKPFANQKPGTSGLRNKVIAFQQPRYLENFVQSIFNSLDDIEGKTLVVGGDGRYYNDVAIQIIVRMAAANGFAK
IIVGQNGIFSTPAVSCVIRKYEAFGGIVLSASHNPGGPKGDFGIKYNVSNGGPAPEKITDRIFSETKKINQYFISDAAKE
RVDLDKLGIYKIENTTVEVINSVIDYAELMQQIFDFDKVRELFAKGFKVRFDSMCAVSGPYAKYIFETLLKAPAGTVVNA
QPLEDFGGFHPDPNPVNAEDLVKHMRSGKYDFGAASDGDADRNMIVGKQIYVSPSDSLAIMAANAHLIPVYSKGIKGVAR
SMPTSTAVDRVAESLRLSCFETPTGWKFFGNLLDAEKITLCGEESYGTGSNHIREKDGVWAVLFWLNLVAVTGKQVDQLV
EEHWQKFGRNFYSRHDYEAIDTAIANSIIDSLRERLSSLVGAQLNDEKVAKADDFSYIDPIDGSVSNHQGIRIIFEDGSR
IVFRLSGTGTQGATLRIYLEKYESDSSKFSIPTQQALASLIEIAEDLTNIKSLTGMTEPTIVT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=563, Percent_Identity=54.7069271758437, Blast_Score=621, Evalue=1e-178,
Organism=Homo sapiens, GI21361621, Length=561, Percent_Identity=54.0106951871658, Blast_Score=609, Evalue=1e-174,
Organism=Homo sapiens, GI133922562, Length=564, Percent_Identity=47.8723404255319, Blast_Score=540, Evalue=1e-153,
Organism=Homo sapiens, GI290463104, Length=365, Percent_Identity=53.1506849315069, Blast_Score=404, Evalue=1e-112,
Organism=Homo sapiens, GI239741729, Length=135, Percent_Identity=50.3703703703704, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI239743670, Length=135, Percent_Identity=48.1481481481481, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1786904, Length=429, Percent_Identity=28.9044289044289, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17535441, Length=568, Percent_Identity=49.2957746478873, Blast_Score=551, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6323752, Length=567, Percent_Identity=48.6772486772487, Blast_Score=519, Evalue=1e-148,
Organism=Saccharomyces cerevisiae, GI6322722, Length=570, Percent_Identity=45.7894736842105, Blast_Score=483, Evalue=1e-137,
Organism=Drosophila melanogaster, GI17864244, Length=562, Percent_Identity=48.7544483985765, Blast_Score=551, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59743; Mature: 59612

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQTVSTKPFANQKPGTSGLRNKVIAFQQPRYLENFVQSIFNSLDDIEGKTLVVGGDGR
CCCCCCCCCCCCCCCCCCCHHHHCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCCCC
YYNDVAIQIIVRMAAANGFAKIIVGQNGIFSTPAVSCVIRKYEAFGGIVLSASHNPGGPK
EEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCC
GDFGIKYNVSNGGPAPEKITDRIFSETKKINQYFISDAAKERVDLDKLGIYKIENTTVEV
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEECCHHHHH
INSVIDYAELMQQIFDFDKVRELFAKGFKVRFDSMCAVSGPYAKYIFETLLKAPAGTVVN
HHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCEEC
AQPLEDFGGFHPDPNPVNAEDLVKHMRSGKYDFGAASDGDADRNMIVGKQIYVSPSDSLA
CCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCEEEECCCCCEE
IMAANAHLIPVYSKGIKGVARSMPTSTAVDRVAESLRLSCFETPTGWKFFGNLLDAEKIT
EEEECCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEE
LCGEESYGTGSNHIREKDGVWAVLFWLNLVAVTGKQVDQLVEEHWQKFGRNFYSRHDYEA
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IDTAIANSIIDSLRERLSSLVGAQLNDEKVAKADDFSYIDPIDGSVSNHQGIRIIFEDGS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
RIVFRLSGTGTQGATLRIYLEKYESDSSKFSIPTQQALASLIEIAEDLTNIKSLTGMTEP
EEEEEEECCCCCCCEEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
TIVT
CEEC
>Mature Secondary Structure 
AIQTVSTKPFANQKPGTSGLRNKVIAFQQPRYLENFVQSIFNSLDDIEGKTLVVGGDGR
CCCCCCCCCCCCCCCCCCHHHHCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCCCC
YYNDVAIQIIVRMAAANGFAKIIVGQNGIFSTPAVSCVIRKYEAFGGIVLSASHNPGGPK
EEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCC
GDFGIKYNVSNGGPAPEKITDRIFSETKKINQYFISDAAKERVDLDKLGIYKIENTTVEV
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEECCHHHHH
INSVIDYAELMQQIFDFDKVRELFAKGFKVRFDSMCAVSGPYAKYIFETLLKAPAGTVVN
HHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCEEC
AQPLEDFGGFHPDPNPVNAEDLVKHMRSGKYDFGAASDGDADRNMIVGKQIYVSPSDSLA
CCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCEEEECCCCCEE
IMAANAHLIPVYSKGIKGVARSMPTSTAVDRVAESLRLSCFETPTGWKFFGNLLDAEKIT
EEEECCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEE
LCGEESYGTGSNHIREKDGVWAVLFWLNLVAVTGKQVDQLVEEHWQKFGRNFYSRHDYEA
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IDTAIANSIIDSLRERLSSLVGAQLNDEKVAKADDFSYIDPIDGSVSNHQGIRIIFEDGS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
RIVFRLSGTGTQGATLRIYLEKYESDSSKFSIPTQQALASLIEIAEDLTNIKSLTGMTEP
EEEEEEECCCCCCCEEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
TIVT
CEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]