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The map label for this gene is mtnN [H]

Identifier: 89255873

GI number: 89255873

Start: 437997

End: 438683

Strand: Direct

Name: mtnN [H]

Synonym: FTL_0463

Alternate gene names: 89255873

Gene position: 437997-438683 (Clockwise)

Preceding gene: 89255872

Following gene: 89255876

Centisome position: 23.1

GC content: 33.77

Gene sequence:

>687_bases
ATGAGAAAAATTGCAATATTAGGAGCAATGGAGATAGAAATTTTACCAATTCTAGCTAAGTTAGATAACTATGAAACTAT
AGAATATGCAAATAACAAATATTATCTAGCAAATTATCAGGATAAAGAGCTTGTAATAGCTTATAGTAAAATTGGTAAAG
TATTCTCAAGCTTAACAGCAACGATAATGATTGAGCGCTTTGGTGTTGAGGCATTATTGTTTAGCGGTGTTGCTGGGGGG
CTACAAGATTTGAAAGTAGGTGATATGATTGCTGCAACTGCTACAGTACAACACGATGTTGATATCACCGCATTTGGCTA
TCCATATGGTAAGATTCCTATATCGGAAGTTGAAATTAAAACATCGGCTAAACTTTTAAAACAAGCACAAAATGTTGCTA
ATGAACTTGGTCTTAATCTACATACTGGTGTTATAGCTACAGGAGATCAATTTGTTCATTGTGCAGAGAGAAAAGATTTT
GTAATCAAAGAGTTTGATGCAAAGGCTATAGAAATGGAAGGAGCAAGTGTTAATCTTATCTGTAATGAAATGGGTGTGCC
AAGTTTAATTCTAAGAAGTATTTCTGACACTGCTGATGGCGATGCACCTGAAAATTTTGATGAGTTTGCTAAGATAGCTG
CTAAAAGATCCGCAAACTTTATAATGCAAATACTTAGTAATATATAA

Upstream 100 bases:

>100_bases
AGACTTATTATAGCGATAAACCATCTGGTGGTGGTGTGCTATTACCTCAAGGCTTCAGAAAAATAACTAAAATTGATATA
GAAAATATAGAGAGTGAATA

Downstream 100 bases:

>100_bases
TCTTATCTTTATGCTGTTTATTTTTTGTTGTTATTAATGCCCGAGATATTTCAATAATACATATCACTAGTAAAATCGGA
TCTAAGAGATAGTCCCATAT

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MRKIAILGAMEIEILPILAKLDNYETIEYANNKYYLANYQDKELVIAYSKIGKVFSSLTATIMIERFGVEALLFSGVAGG
LQDLKVGDMIAATATVQHDVDITAFGYPYGKIPISEVEIKTSAKLLKQAQNVANELGLNLHTGVIATGDQFVHCAERKDF
VIKEFDAKAIEMEGASVNLICNEMGVPSLILRSISDTADGDAPENFDEFAKIAAKRSANFIMQILSNI

Sequences:

>Translated_228_residues
MRKIAILGAMEIEILPILAKLDNYETIEYANNKYYLANYQDKELVIAYSKIGKVFSSLTATIMIERFGVEALLFSGVAGG
LQDLKVGDMIAATATVQHDVDITAFGYPYGKIPISEVEIKTSAKLLKQAQNVANELGLNLHTGVIATGDQFVHCAERKDF
VIKEFDAKAIEMEGASVNLICNEMGVPSLILRSISDTADGDAPENFDEFAKIAAKRSANFIMQILSNI
>Mature_228_residues
MRKIAILGAMEIEILPILAKLDNYETIEYANNKYYLANYQDKELVIAYSKIGKVFSSLTATIMIERFGVEALLFSGVAGG
LQDLKVGDMIAATATVQHDVDITAFGYPYGKIPISEVEIKTSAKLLKQAQNVANELGLNLHTGVIATGDQFVHCAERKDF
VIKEFDAKAIEMEGASVNLICNEMGVPSLILRSISDTADGDAPENFDEFAKIAAKRSANFIMQILSNI

Specific function: Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=228, Percent_Identity=35.0877192982456, Blast_Score=121, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 24917; Mature: 24917

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIAILGAMEIEILPILAKLDNYETIEYANNKYYLANYQDKELVIAYSKIGKVFSSLTA
CCEEEEEEEEEHHEEEHHHHCCCCCEEEECCCEEEEECCCCCEEEEEHHHHHHHHHHHHH
TIMIERFGVEALLFSGVAGGLQDLKVGDMIAATATVQHDVDITAFGYPYGKIPISEVEIK
HHHHHHHCHHHHHHHHHCCCHHHCCCCHHHHHEEEEECCCEEEEECCCCCCCCHHHEEHH
TSAKLLKQAQNVANELGLNLHTGVIATGDQFVHCAERKDFVIKEFDAKAIEMEGASVNLI
HHHHHHHHHHHHHHHHCCCEECCEEECCCHHEEECCCCCCEEEECCCEEEEECCCEEEEE
CNEMGVPSLILRSISDTADGDAPENFDEFAKIAAKRSANFIMQILSNI
ECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKIAILGAMEIEILPILAKLDNYETIEYANNKYYLANYQDKELVIAYSKIGKVFSSLTA
CCEEEEEEEEEHHEEEHHHHCCCCCEEEECCCEEEEECCCCCEEEEEHHHHHHHHHHHHH
TIMIERFGVEALLFSGVAGGLQDLKVGDMIAATATVQHDVDITAFGYPYGKIPISEVEIK
HHHHHHHCHHHHHHHHHCCCHHHCCCCHHHHHEEEEECCCEEEEECCCCCCCCHHHEEHH
TSAKLLKQAQNVANELGLNLHTGVIATGDQFVHCAERKDFVIKEFDAKAIEMEGASVNLI
HHHHHHHHHHHHHHHHCCCEECCEEECCCHHEEECCCCCCEEEECCCEEEEECCCEEEEE
CNEMGVPSLILRSISDTADGDAPENFDEFAKIAAKRSANFIMQILSNI
ECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]