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The map label for this gene is 89255840

Identifier: 89255840

GI number: 89255840

Start: 397264

End: 398145

Strand: Direct

Name: 89255840

Synonym: FTL_0430

Alternate gene names: NA

Gene position: 397264-398145 (Clockwise)

Preceding gene: 89255839

Following gene: 89255841

Centisome position: 20.95

GC content: 31.52

Gene sequence:

>882_bases
ATGCGACAAATAAATAGACTGGTAGTTTTTGGAGATAGTCTTTTAGATAATGGTAATATCATGAAGACATTGGACATACC
AGGTAAGCCATACCATGATGGCAGATTTTCAAATGGTCTAGTATCAACAGAGGTTTTAGCACAGATGTTAGCTAAAGATC
AGAAACTATCAGAAATTAAACATAAAAATTATGCAATTGGAGGAGCGTTGACACATGGGACAAATCCATCATCATTGCTA
AGATTTCACTCTTTTTCTGTATCAGAACAAATTATCAGATTTGAAAATGAAGAAGGAAGATTTGCTGATGATGACTTGGT
TGTAATAAATGGTGGTGCAAATAATTTTATGTTTATGGTTTATAATGAGATTCCATATATAAACCTGGTTCCAAAATTCA
GAGTAGCAAGAGACCTAAATAAGATCGTTAGGAAAACTATAAAAATGGGGGCTAAAAATATAATATTGTGGAACATTCCT
GATGTTACTAAAGCACCAGCATATAAAGATTATCTCTCTAATTGGGTAGGTAAGTTTTTTAAATCATATATGCAAATAAA
TGTGAATCTTCAAAATGGTTTATTAAGAAATCGTGTTTCTGAATTACAAGCAATTTTTCCTCATATAAACCTTAAGCTTT
TTGATTTTTATAGTTTATTAAATGATTGTGTTGAAAATCCTGCTAAATATGGTTTTGAAAATGTTACCGATGCCTGTATT
GATAGTTATGGTGGTGCTGACTCACTGGGTAATATTCAATATGATATAGAAATAATGGGTGATCCAGAGAAGTACTTATG
TTGGGATTATTGTCATCCGACAGCAAAAGCAAATAGGTTAGTTGCGAGTAAAATGTTTGATTTATGGAAGCTTGATATAT
GA

Upstream 100 bases:

>100_bases
AAAATGAGTTTCATCATGCTTTAGAAAGCCTAAGAATTAGAGATAATAGCTTAATAATAGCCCATTGGATGGCTAATTTT
TTTGAGTACAAGGATTAAAT

Downstream 100 bases:

>100_bases
GTCAAGATTTAATAGCGCAGCTTGAGTTTATTAGTGAGCTTGAGAAGCTAAAAAGAGTTTACTGCCAAACTTGGTTACCA
TGTGATGGTGGTCGTCATGA

Product: hypothetical protein

Products: NA

Alternate protein names: TL; Atypical phospholipase; Lecithin-dependent hemolysin; LDH; Lysophospholipase; Phospholipase A2 [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MRQINRLVVFGDSLLDNGNIMKTLDIPGKPYHDGRFSNGLVSTEVLAQMLAKDQKLSEIKHKNYAIGGALTHGTNPSSLL
RFHSFSVSEQIIRFENEEGRFADDDLVVINGGANNFMFMVYNEIPYINLVPKFRVARDLNKIVRKTIKMGAKNIILWNIP
DVTKAPAYKDYLSNWVGKFFKSYMQINVNLQNGLLRNRVSELQAIFPHINLKLFDFYSLLNDCVENPAKYGFENVTDACI
DSYGGADSLGNIQYDIEIMGDPEKYLCWDYCHPTAKANRLVASKMFDLWKLDI

Sequences:

>Translated_293_residues
MRQINRLVVFGDSLLDNGNIMKTLDIPGKPYHDGRFSNGLVSTEVLAQMLAKDQKLSEIKHKNYAIGGALTHGTNPSSLL
RFHSFSVSEQIIRFENEEGRFADDDLVVINGGANNFMFMVYNEIPYINLVPKFRVARDLNKIVRKTIKMGAKNIILWNIP
DVTKAPAYKDYLSNWVGKFFKSYMQINVNLQNGLLRNRVSELQAIFPHINLKLFDFYSLLNDCVENPAKYGFENVTDACI
DSYGGADSLGNIQYDIEIMGDPEKYLCWDYCHPTAKANRLVASKMFDLWKLDI
>Mature_293_residues
MRQINRLVVFGDSLLDNGNIMKTLDIPGKPYHDGRFSNGLVSTEVLAQMLAKDQKLSEIKHKNYAIGGALTHGTNPSSLL
RFHSFSVSEQIIRFENEEGRFADDDLVVINGGANNFMFMVYNEIPYINLVPKFRVARDLNKIVRKTIKMGAKNIILWNIP
DVTKAPAYKDYLSNWVGKFFKSYMQINVNLQNGLLRNRVSELQAIFPHINLKLFDFYSLLNDCVENPAKYGFENVTDACI
DSYGGADSLGNIQYDIEIMGDPEKYLCWDYCHPTAKANRLVASKMFDLWKLDI

Specific function: Phospholipase hydrolyzing both fatty acid esters of phospholipid, i.e., it hydrolyzes phosphatidylcholine (PC) to lysophosphatidylcholine (LPC) and then LPC to glycerophosphorylcholine (GPC) [H]

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: 3.1.1.-

Molecular weight: Translated: 33411; Mature: 33411

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQINRLVVFGDSLLDNGNIMKTLDIPGKPYHDGRFSNGLVSTEVLAQMLAKDQKLSEIK
CCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHH
HKNYAIGGALTHGTNPSSLLRFHSFSVSEQIIRFENEEGRFADDDLVVINGGANNFMFMV
HCCEEECCEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCCEEEEE
YNEIPYINLVPKFRVARDLNKIVRKTIKMGAKNIILWNIPDVTKAPAYKDYLSNWVGKFF
ECCCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
KSYMQINVNLQNGLLRNRVSELQAIFPHINLKLFDFYSLLNDCVENPAKYGFENVTDACI
HHHHEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHCCHHHHHHHHH
DSYGGADSLGNIQYDIEIMGDPEKYLCWDYCHPTAKANRLVASKMFDLWKLDI
HCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRQINRLVVFGDSLLDNGNIMKTLDIPGKPYHDGRFSNGLVSTEVLAQMLAKDQKLSEIK
CCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHH
HKNYAIGGALTHGTNPSSLLRFHSFSVSEQIIRFENEEGRFADDDLVVINGGANNFMFMV
HCCEEECCEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCCEEEEE
YNEIPYINLVPKFRVARDLNKIVRKTIKMGAKNIILWNIPDVTKAPAYKDYLSNWVGKFF
ECCCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
KSYMQINVNLQNGLLRNRVSELQAIFPHINLKLFDFYSLLNDCVENPAKYGFENVTDACI
HHHHEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHCCHHHHHHHHH
DSYGGADSLGNIQYDIEIMGDPEKYLCWDYCHPTAKANRLVASKMFDLWKLDI
HCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3508495; 12620739; 1791426 [H]