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The map label for this gene is cry2 [H]

Identifier: 89255767

GI number: 89255767

Start: 322844

End: 323338

Strand: Direct

Name: cry2 [H]

Synonym: FTL_0342

Alternate gene names: 89255767

Gene position: 322844-323338 (Clockwise)

Preceding gene: 89255766

Following gene: 89255768

Centisome position: 17.03

GC content: 35.76

Gene sequence:

>495_bases
ATGCGTTCATTTTTATCACGTTTGCGTTGGCATTGTCATTTTATGCAGAAGTTAGAGGATCAACCAAGTATTGAATATGA
GAATTTGCATTCAGCTTATGATCAACTACGTACAGAACTGCTAAATCAACAATGTTTTGAAGCATGGAAAACTGGCAATA
CTGGTTATCCAATGATAGATGCTTGTATGCGAGCTTTGATTGCGACAAGGTGGCTAAATTTTCGTATGCGTGCAATGCTT
ATGAGTTTTGCAAGCTATCATTTGTGGTTAGATTGGCGTGTTACATCGCTATATTTAGCAGGATTATTTACTGATTATGA
GCCAGGTATTCATTACTCACAAGTACAAATGCAATCTGGGACTACAGGTATTAATAGTATCCGTATTTATAACCCTATTA
AGCAAAGCATTGACCAATATCCTAATGTCGAGTTTATTCGAAGATGGCTACCTGAACTAGAAAATGTAAGTAATGAAAAT
ATTCATACTCCATAG

Upstream 100 bases:

>100_bases
TGGAGTTATTTCGTTAAAAGAGATATACCAGAAAGCTAATTAGCGTAAAAATGAAATCAAAGAAAGTAGCGTAAAAAATA
AAACAAAATGGTTAAGTGCA

Downstream 100 bases:

>100_bases
TTAGAAAAACATAATTCTCTAGATTATCTAGATCCAACCATTGATGAAAAACAAGCACGTAAATTTGCTGCAGATAATAT
TTATAAAATTAGAAAAAGCT

Product: deoxyribodipyrimidine photolyase

Products: 2 pyrimidine residues (in DNA) [C]

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MRSFLSRLRWHCHFMQKLEDQPSIEYENLHSAYDQLRTELLNQQCFEAWKTGNTGYPMIDACMRALIATRWLNFRMRAML
MSFASYHLWLDWRVTSLYLAGLFTDYEPGIHYSQVQMQSGTTGINSIRIYNPIKQSIDQYPNVEFIRRWLPELENVSNEN
IHTP

Sequences:

>Translated_164_residues
MRSFLSRLRWHCHFMQKLEDQPSIEYENLHSAYDQLRTELLNQQCFEAWKTGNTGYPMIDACMRALIATRWLNFRMRAML
MSFASYHLWLDWRVTSLYLAGLFTDYEPGIHYSQVQMQSGTTGINSIRIYNPIKQSIDQYPNVEFIRRWLPELENVSNEN
IHTP
>Mature_164_residues
MRSFLSRLRWHCHFMQKLEDQPSIEYENLHSAYDQLRTELLNQQCFEAWKTGNTGYPMIDACMRALIATRWLNFRMRAML
MSFASYHLWLDWRVTSLYLAGLFTDYEPGIHYSQVQMQSGTTGINSIRIYNPIKQSIDQYPNVEFIRRWLPELENVSNEN
IHTP

Specific function: Has no photolyase activity [H]

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Escherichia coli, GI1786926, Length=125, Percent_Identity=36, Blast_Score=85, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324962, Length=129, Percent_Identity=34.8837209302326, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: 4.1.99.3 [C]

Molecular weight: Translated: 19590; Mature: 19590

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00394 DNA_PHOTOLYASES_1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSFLSRLRWHCHFMQKLEDQPSIEYENLHSAYDQLRTELLNQQCFEAWKTGNTGYPMID
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ACMRALIATRWLNFRMRAMLMSFASYHLWLDWRVTSLYLAGLFTDYEPGIHYSQVQMQSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECCCC
TTGINSIRIYNPIKQSIDQYPNVEFIRRWLPELENVSNENIHTP
CCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRSFLSRLRWHCHFMQKLEDQPSIEYENLHSAYDQLRTELLNQQCFEAWKTGNTGYPMID
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ACMRALIATRWLNFRMRAMLMSFASYHLWLDWRVTSLYLAGLFTDYEPGIHYSQVQMQSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECCCC
TTGINSIRIYNPIKQSIDQYPNVEFIRRWLPELENVSNENIHTP
CCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: ATP; FADH2; Flavin; pterin [C]

Metal ions: NA

Kcat value (1/min): 2.4 [C]

Specific activity: NA

Km value (mM): NA

Substrates: cyclobutadipyrimidine (in DNA) [C]

Specific reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA) [C]

General reaction: C-C-bond cleavage [C]

Inhibitor: yeast DNA [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]