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The map label for this gene is aceE [H]

Identifier: 89255740

GI number: 89255740

Start: 295558

End: 298239

Strand: Direct

Name: aceE [H]

Synonym: FTL_0309

Alternate gene names: 89255740

Gene position: 295558-298239 (Clockwise)

Preceding gene: 89255739

Following gene: 89255741

Centisome position: 15.59

GC content: 38.29

Gene sequence:

>2682_bases
ATGTCGGATTTCACTAAAGATATTGATGTTTTAGAAACCCAAGAATGGCTTGAGGCTTTTGAAGATGTCATAAAAAGAGA
AGGTGCTGATAGAGCCAAGTTTTTATTTGAACAATTACTTGCTAAAGGTTCCGAGCTTGGTATAAAAAGTGCTTACTCAA
CTGCTAAAGTTAAGAACTATGTCAACTCTATAGATGTCTCTGAACAACCAAGTTATCCAGGAGATATAGAGCTTGAACAA
AAGATTGAAGCTATCAATAGATGGAACTCTACAGTTATAGTAGCTGCAGCTAATAAGAAAGATGGTTCTATAGGTGGACA
TATTGGTACTGGTGCCGGCGCTATGACGCTTTATGAAGTAGGTTTCAACCATTTTTGGAAAGCACCCAATGATGAACATG
CTGGTGATTTGATATTCTATCAAGGACATCTTTCTCCTATTGTTTATGCGCGTTCATTCCTAGAAGGTAGAATAACTGCA
GAACAGTTAGAAAACTTTAGAAAGCAAGCATTTAATGGGCAAAATGCGGTATCTTCATATCCTCATCCTTATCTACAACC
GACTTATTGGCAGTTCCCAACTGTTTCTATGGGGTTAGGACCACTTCAAGCTATTTATCAAGCTAGATTTATGAAGTATC
TAGAGGCTAGGGGTTTAGCAAAAACATCTGATCGCAAAGTTTGGGCATTCTGTGGTGATGGCGAGATGGATGAGCCAGAA
TCAATTGGTTCTATCACTAGAGCAGGTCGTGAAGGGCTGGATAACCTTATATTTGTAGTTAATTGTAATCTACAAAGGCT
AGATGGTCTGGTAAATGGTAATGGTAATATTGTTGAAGAATTAGCAGATGTATTTGCTGGTGCTGGTTGGAATGTTATCA
AGGTGTTGTGGAGTAGTGACTGGGATAAATTATTACAAGATCCAAGAGGTGGTAAAAAACTTGCTCAAAGGTTAAGTGAA
TTAAATGATGGACAATTCCATACAATTAAAGCTCATGGTGGTGCTGAGTGTCGTAGAGTTGTCTTTAGCGGTGATGAAGA
TTTAGAAGCGCTAGCTAAGGATATGACAGATGATGATATTCAAGCATTACGTCGTGGAGGCCATGATCCATTGAAAATTT
ATGCAGCATATAAGAAGGCGGTAGAGAATCCAAATGGTCGTCCAACACTAATTCTTCCTATGACTGTTAAGGGCTATGGT
TTAGGGGAGTGGGGTGAGTCAAAAAATATTGCCCACAATGTCAAAAAACTTGATACTGATGCACTTGAGCACATCAAAAA
TAGATTCAATGTCCCGGCTTCAAAAGAGGATATCGAAAACTATAGACTCATCAAGCTAGATGAAAATTCGCCTGAGATGA
AATATCTACACTCTAAGAGAAAAGACCTAGGTGGTTATATTCCTAAGAGATTGGAGAATAAGCAAGCATTAGAGATTCCA
AGCTATAAAGATTTTGCTAAGAGCTTATTGGATGATAGTGGTGATAGAGAATTTTCAACTACTACCGCATTTGTAAGAAT
ATTATCCTACTTGGCAAAAGATAAGAATCTAGGGAAGCATATTGTACCAATCACGGTAGACGAGTCACGTACTTTTGGTA
TGGAGGGCTTGTTTAGGCAGTTAGGTATCTATAACCCACATGGTCAGCAATATGTGCCAGAAGATAAACAGCAAGTAATG
TTCTATAAAGAGTCTGTAGATGGTCAGATTTTACAAGAAGGTATTAATGAGCAAGGAGGTTTTTGTTCTTGGATTGCCGC
AGCTACTTCATATAGCGTACACAAGGTTCCAATGATTCCTTTCATGATTTACTACTCAATGTTTGGTTTCCAAAGATTTG
GTGATCTTGCTTGGGCAGCTGGCGATTCGATGGCAAAAGGTTTTGTAATTGGTGGGACTTCAGGACGTACAACTCTAAAT
GGCGAAGGTTTGCAGCATGAAGATGGTCATAGCCATATCCAAGCTGGTCTTATACCTAATTGTATCTCTTATGATCCTAC
ATATGCTTATGAATTAGCTGTAATCCTTGGCGAAGGTATGAAGAGAATGTATGTTGATGGTGATCATGTATATTACTATA
TTACAGTAATGAATGAGAACTACTTTCATAGAGCGATGCCAGAGGGCTGTGAAGAAGGTATCATCAAGGGCTTATATAAG
TTAGATGAAGAGAAAAAGCCAGCATCTAAGCATGTACAGCTATTGGGTTCTGGTTCTATTCTAAGAGAAGTTGAAGCTGC
AGCTAAGATGCTAAAAGAAGAGTATGGAATTACTTCTAATGTTTGGAGTATGACTTCAGCAAATGAGCTTTATAGAGAAG
CTAAAGATGTAGCTAGAGCTAATATGCTTCACCCAACAGCAGAGAAAAAAGAAAGCTATATCGAGAAGTGCTTTAAAAAT
GAGCAAGGTCCTGTAATCGCTTCTACGGACTATATTAAGCTTTATACTGATCAGTTAAGAGAATTTATACCGCATACTTT
TGTGAACTTAGGTACAGACGGCTTTGGTAGATCTGATACTCGAGCAGCGCTAAGAAGTTTCTTTGAGGTTGATAGATATC
ATGTCGTTGTTGCTTCATTATATGCTCTATATTTAGATGGCAAAGTTGAGGCTAGCGAAGTTAAAGCTGCGATTGAGAAG
TACAATATAGATCCAGAGCGTATGGCACCTTTTTATAGCTAA

Upstream 100 bases:

>100_bases
TTAACAAGCTTGTTACTGGTTGATGTTGTCTATCTATTGACTTATAATCGAGCAATAAGTTTTAATTTCGTTAATATTCG
ATTAATTCGGAGGATAAAGG

Downstream 100 bases:

>100_bases
TTGGTAAGGAGATATTAATGTCTATAGAGATAGTTAAAGTCCCTGATATTGGGGATTATGATAACGTTGATGTGATCGAG
GTTAATGTTGCTGTAGGTGA

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 893; Mature: 892

Protein sequence:

>893_residues
MSDFTKDIDVLETQEWLEAFEDVIKREGADRAKFLFEQLLAKGSELGIKSAYSTAKVKNYVNSIDVSEQPSYPGDIELEQ
KIEAINRWNSTVIVAAANKKDGSIGGHIGTGAGAMTLYEVGFNHFWKAPNDEHAGDLIFYQGHLSPIVYARSFLEGRITA
EQLENFRKQAFNGQNAVSSYPHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRKVWAFCGDGEMDEPE
SIGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSDWDKLLQDPRGGKKLAQRLSE
LNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDDDIQALRRGGHDPLKIYAAYKKAVENPNGRPTLILPMTVKGYG
LGEWGESKNIAHNVKKLDTDALEHIKNRFNVPASKEDIENYRLIKLDENSPEMKYLHSKRKDLGGYIPKRLENKQALEIP
SYKDFAKSLLDDSGDREFSTTTAFVRILSYLAKDKNLGKHIVPITVDESRTFGMEGLFRQLGIYNPHGQQYVPEDKQQVM
FYKESVDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIPFMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLN
GEGLQHEDGHSHIQAGLIPNCISYDPTYAYELAVILGEGMKRMYVDGDHVYYYITVMNENYFHRAMPEGCEEGIIKGLYK
LDEEKKPASKHVQLLGSGSILREVEAAAKMLKEEYGITSNVWSMTSANELYREAKDVARANMLHPTAEKKESYIEKCFKN
EQGPVIASTDYIKLYTDQLREFIPHTFVNLGTDGFGRSDTRAALRSFFEVDRYHVVVASLYALYLDGKVEASEVKAAIEK
YNIDPERMAPFYS

Sequences:

>Translated_893_residues
MSDFTKDIDVLETQEWLEAFEDVIKREGADRAKFLFEQLLAKGSELGIKSAYSTAKVKNYVNSIDVSEQPSYPGDIELEQ
KIEAINRWNSTVIVAAANKKDGSIGGHIGTGAGAMTLYEVGFNHFWKAPNDEHAGDLIFYQGHLSPIVYARSFLEGRITA
EQLENFRKQAFNGQNAVSSYPHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRKVWAFCGDGEMDEPE
SIGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSDWDKLLQDPRGGKKLAQRLSE
LNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDDDIQALRRGGHDPLKIYAAYKKAVENPNGRPTLILPMTVKGYG
LGEWGESKNIAHNVKKLDTDALEHIKNRFNVPASKEDIENYRLIKLDENSPEMKYLHSKRKDLGGYIPKRLENKQALEIP
SYKDFAKSLLDDSGDREFSTTTAFVRILSYLAKDKNLGKHIVPITVDESRTFGMEGLFRQLGIYNPHGQQYVPEDKQQVM
FYKESVDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIPFMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLN
GEGLQHEDGHSHIQAGLIPNCISYDPTYAYELAVILGEGMKRMYVDGDHVYYYITVMNENYFHRAMPEGCEEGIIKGLYK
LDEEKKPASKHVQLLGSGSILREVEAAAKMLKEEYGITSNVWSMTSANELYREAKDVARANMLHPTAEKKESYIEKCFKN
EQGPVIASTDYIKLYTDQLREFIPHTFVNLGTDGFGRSDTRAALRSFFEVDRYHVVVASLYALYLDGKVEASEVKAAIEK
YNIDPERMAPFYS
>Mature_892_residues
SDFTKDIDVLETQEWLEAFEDVIKREGADRAKFLFEQLLAKGSELGIKSAYSTAKVKNYVNSIDVSEQPSYPGDIELEQK
IEAINRWNSTVIVAAANKKDGSIGGHIGTGAGAMTLYEVGFNHFWKAPNDEHAGDLIFYQGHLSPIVYARSFLEGRITAE
QLENFRKQAFNGQNAVSSYPHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRKVWAFCGDGEMDEPES
IGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSDWDKLLQDPRGGKKLAQRLSEL
NDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDDDIQALRRGGHDPLKIYAAYKKAVENPNGRPTLILPMTVKGYGL
GEWGESKNIAHNVKKLDTDALEHIKNRFNVPASKEDIENYRLIKLDENSPEMKYLHSKRKDLGGYIPKRLENKQALEIPS
YKDFAKSLLDDSGDREFSTTTAFVRILSYLAKDKNLGKHIVPITVDESRTFGMEGLFRQLGIYNPHGQQYVPEDKQQVMF
YKESVDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIPFMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLNG
EGLQHEDGHSHIQAGLIPNCISYDPTYAYELAVILGEGMKRMYVDGDHVYYYITVMNENYFHRAMPEGCEEGIIKGLYKL
DEEKKPASKHVQLLGSGSILREVEAAAKMLKEEYGITSNVWSMTSANELYREAKDVARANMLHPTAEKKESYIEKCFKNE
QGPVIASTDYIKLYTDQLREFIPHTFVNLGTDGFGRSDTRAALRSFFEVDRYHVVVASLYALYLDGKVEASEVKAAIEKY
NIDPERMAPFYS

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=890, Percent_Identity=56.1797752808989, Blast_Score=1011, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 100269; Mature: 100138

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFTKDIDVLETQEWLEAFEDVIKREGADRAKFLFEQLLAKGSELGIKSAYSTAKVKNY
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VNSIDVSEQPSYPGDIELEQKIEAINRWNSTVIVAAANKKDGSIGGHIGTGAGAMTLYEV
HHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHH
GFNHFWKAPNDEHAGDLIFYQGHLSPIVYARSFLEGRITAEQLENFRKQAFNGQNAVSSY
HHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
PHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRKVWAFCGDGEMDEPE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCH
SIGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSD
HHHHHHHHHHHCCCCEEEEEECCHHHHCCEECCCCHHHHHHHHHHCCCCCCEEHEECCCC
WDKLLQDPRGGKKLAQRLSELNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDDDI
HHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHEEEECCCHHHHHHHHCCCCHHH
QALRRGGHDPLKIYAAYKKAVENPNGRPTLILPMTVKGYGLGEWGESKNIAHNVKKLDTD
HHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
ALEHIKNRFNVPASKEDIENYRLIKLDENSPEMKYLHSKRKDLGGYIPKRLENKQALEIP
HHHHHHHHCCCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCC
SYKDFAKSLLDDSGDREFSTTTAFVRILSYLAKDKNLGKHIVPITVDESRTFGMEGLFRQ
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHH
LGIYNPHGQQYVPEDKQQVMFYKESVDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIP
HCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCEECCCHHH
FMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLNGEGLQHEDGHSHIQAGLIPN
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCHHHHHCCCCC
CISYDPTYAYELAVILGEGMKRMYVDGDHVYYYITVMNENYFHRAMPEGCEEGIIKGLYK
CCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEEEEECCCHHHHHCCCHHHHHHHHHHHH
LDEEKKPASKHVQLLGSGSILREVEAAAKMLKEEYGITSNVWSMTSANELYREAKDVARA
HCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHH
NMLHPTAEKKESYIEKCFKNEQGPVIASTDYIKLYTDQLREFIPHTFVNLGTDGFGRSDT
HCCCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RAALRSFFEVDRYHVVVASLYALYLDGKVEASEVKAAIEKYNIDPERMAPFYS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHCCCCCC
>Mature Secondary Structure 
SDFTKDIDVLETQEWLEAFEDVIKREGADRAKFLFEQLLAKGSELGIKSAYSTAKVKNY
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VNSIDVSEQPSYPGDIELEQKIEAINRWNSTVIVAAANKKDGSIGGHIGTGAGAMTLYEV
HHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHH
GFNHFWKAPNDEHAGDLIFYQGHLSPIVYARSFLEGRITAEQLENFRKQAFNGQNAVSSY
HHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
PHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRKVWAFCGDGEMDEPE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCH
SIGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSD
HHHHHHHHHHHCCCCEEEEEECCHHHHCCEECCCCHHHHHHHHHHCCCCCCEEHEECCCC
WDKLLQDPRGGKKLAQRLSELNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDDDI
HHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHEEEECCCHHHHHHHHCCCCHHH
QALRRGGHDPLKIYAAYKKAVENPNGRPTLILPMTVKGYGLGEWGESKNIAHNVKKLDTD
HHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
ALEHIKNRFNVPASKEDIENYRLIKLDENSPEMKYLHSKRKDLGGYIPKRLENKQALEIP
HHHHHHHHCCCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCC
SYKDFAKSLLDDSGDREFSTTTAFVRILSYLAKDKNLGKHIVPITVDESRTFGMEGLFRQ
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHH
LGIYNPHGQQYVPEDKQQVMFYKESVDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIP
HCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCEECCCHHH
FMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLNGEGLQHEDGHSHIQAGLIPN
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCHHHHHCCCCC
CISYDPTYAYELAVILGEGMKRMYVDGDHVYYYITVMNENYFHRAMPEGCEEGIIKGLYK
CCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEEEEECCCHHHHHCCCHHHHHHHHHHHH
LDEEKKPASKHVQLLGSGSILREVEAAAKMLKEEYGITSNVWSMTSANELYREAKDVARA
HCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHH
NMLHPTAEKKESYIEKCFKNEQGPVIASTDYIKLYTDQLREFIPHTFVNLGTDGFGRSDT
HCCCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RAALRSFFEVDRYHVVVASLYALYLDGKVEASEVKAAIEKYNIDPERMAPFYS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9171401; 10984043 [H]