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The map label for this gene is cyoB [H]

Identifier: 89255626

GI number: 89255626

Start: 193406

End: 195436

Strand: Direct

Name: cyoB [H]

Synonym: FTL_0192

Alternate gene names: 89255626

Gene position: 193406-195436 (Clockwise)

Preceding gene: 89255625

Following gene: 89255627

Centisome position: 10.2

GC content: 37.52

Gene sequence:

>2031_bases
ATGCTAGAAGCATTAATTGGAAAATTAAGTAATCCGCATTTAGTGTTTCCATACCTATATGAACCAGTAAGTCAACAGTT
AATTATATTAACAATGTTTATTGGAATCGTAGTCGCAGGTGTGGCATTACTAGGCGGTATTACATATTTTAGAAAATGGG
GTTACTTATGGAATGAGTGGTTCACTACTATTGACCATAAGAAAATAGGTACTATGTATACTATCGTAGCATTAGTGATG
ATGTTCCGTGGTTTTGTTGATGCTGCGATGATGAGAACACAGCAAGCGTTAGCATCTGGAGATAGTACAGGATATCTAAT
CCCTGAGCATTTTGATCAAATCTTCTCTGCTCATGGTGTAATTATGATTTTCTTTGTGGCGATGCCTCTTATATTTGCAC
TAATGAACTGGGTGATTCCTTTACAGATTGGTGCTAGAGACGTTGCGTTCCCTTATATGAACTCTTTGAGCTTTTGGTTG
TTCGTAGTCGGTGCAATGCTGATAAATATTTCACTATTGGTTGGGGATTTTGCGCACGCTGGTTGGTTAGCTTATCCGCC
ATTCTCAGAAACAACCTATAGCCCTACAGTAGGTACAGACTATTATATTTGGGGTCTACAAATATCTGGTATTGGTTCAC
TAATGACAGGGATTAACTTCTTTGTAACTATTATCAAAATGCGTTGCAAAGGTATGACGTTAATGAAGATGCCTATCTTT
ACATGGGCTTCATTATGTTCAGTTATCCTTGTGGTTGCTGCTTTTCCAGTTTTAACTGTGACTTTAGGGTTATTGACTTT
AGATAGATATTTCGGGACTCACTTCTTCACTGTTTCAGGTGGTGGAGACCAAATGATGTATGTCAACCTAATCTGGATTT
GGGGACATCCTGAAGTTTATATTCTTGTATTACCTTTATTCGGGGTATTCTCAGAAGTTGCGGCGACATTCTCTAAGAAG
CCACTTTTTGGATATACAACAATGGTTTGGGCAAGTATAGTTATTACTATCTTGTCGTTTACTGTATGGTTACACCATTT
CTTCACAATGGGTGCGAGTGCAAATGTTAATGCCTTCTTTGGAATTATGACAATGATTATTGCAATTCCTACGGGCGTTA
AGATCTTTAACTGGCTATTTACAATGTATAAAGGTCGTATTACATTTGCAACGCCGATGATGTGGCTGATTGGTTTTATG
ATAGTTTTCTCTGTTGGTGGAATGACAGGGGTATTATTATCTGTACCAGGCGTTGACTTCCAAATGCATAATAGTGTGTT
CTTAATTGCACATTTCCATAATGTTATTATTGGAGGCGTTGTATTTGGTGCCTTTTCTGGTCTTACTTTTTGGTTTCCAA
AAATATTTGGTTTCAAATTAAATGAGCGTTTAGGCAAGTATTCATTCTGGTGCTGGTTTATTGGCTTCTTTGTAGCGTTT
ATGCCATTGTATATATTAGGTACTATGGGTATGACAAGAAGACTGTATCACTATGATGCTGCCACAGGATATCAACCACT
GCTTATAGTTGCTTGGGTTGGTGCAATGATTATTGGTTTAGGAATATTACTACAAATTATACAGATTTTTGTAAGTATTA
AGCAAAGAGACCAAAATCGTGTTGGCGCTGATGCTTGGGGTTATGGTCGCACATTAGAGTGGGGTATACCTTCTCCAGTG
CCTTTCTATAATTTCTCGCATGATCCAGTGGTTGAAAAGCGTGATGCATATTGGGATCATAAGCAAAAGGGTCTAAATGT
AGATAATACTCCTGTAGGTAGTGCTAAGAAATATGAAGATATTAATATGCCAAAAAATACAGCTGTGGGAGTTATAATCG
GAGCATTCAGCTTTGTATTTGGATTCGCTGCAGTATGGCATATTTGGTGGCTTGCTATCGTCGGTGTTGTTGGTATCATT
GGTACTGTATTGTACAGATCATTTGATTATGATATCGATTACTATGTCAAGGCTGATCAAGTTAAAGAAGTTGAGAGTAG
ATATAATCAACAAGGAGAGTTACAAGTATGA

Upstream 100 bases:

>100_bases
ACTATAAGCCAGGAGACATGGCTAGTAATATGTCTGGTATGCACATGCATCATGATATGTAGTGTTATTAATAAGTAGTA
GTTTTAAATAGGAGACAAAT

Downstream 100 bases:

>100_bases
GTACAGTAACTGCAGAACATAATCATCATCATGAACATCATTTTGATGGTTCAAAAAATGTTTTTGGTTTTTGGATATAT
ATTATGAGTGATTGTGTGCT

Product: cytochrome O ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MLEALIGKLSNPHLVFPYLYEPVSQQLIILTMFIGIVVAGVALLGGITYFRKWGYLWNEWFTTIDHKKIGTMYTIVALVM
MFRGFVDAAMMRTQQALASGDSTGYLIPEHFDQIFSAHGVIMIFFVAMPLIFALMNWVIPLQIGARDVAFPYMNSLSFWL
FVVGAMLINISLLVGDFAHAGWLAYPPFSETTYSPTVGTDYYIWGLQISGIGSLMTGINFFVTIIKMRCKGMTLMKMPIF
TWASLCSVILVVAAFPVLTVTLGLLTLDRYFGTHFFTVSGGGDQMMYVNLIWIWGHPEVYILVLPLFGVFSEVAATFSKK
PLFGYTTMVWASIVITILSFTVWLHHFFTMGASANVNAFFGIMTMIIAIPTGVKIFNWLFTMYKGRITFATPMMWLIGFM
IVFSVGGMTGVLLSVPGVDFQMHNSVFLIAHFHNVIIGGVVFGAFSGLTFWFPKIFGFKLNERLGKYSFWCWFIGFFVAF
MPLYILGTMGMTRRLYHYDAATGYQPLLIVAWVGAMIIGLGILLQIIQIFVSIKQRDQNRVGADAWGYGRTLEWGIPSPV
PFYNFSHDPVVEKRDAYWDHKQKGLNVDNTPVGSAKKYEDINMPKNTAVGVIIGAFSFVFGFAAVWHIWWLAIVGVVGII
GTVLYRSFDYDIDYYVKADQVKEVESRYNQQGELQV

Sequences:

>Translated_676_residues
MLEALIGKLSNPHLVFPYLYEPVSQQLIILTMFIGIVVAGVALLGGITYFRKWGYLWNEWFTTIDHKKIGTMYTIVALVM
MFRGFVDAAMMRTQQALASGDSTGYLIPEHFDQIFSAHGVIMIFFVAMPLIFALMNWVIPLQIGARDVAFPYMNSLSFWL
FVVGAMLINISLLVGDFAHAGWLAYPPFSETTYSPTVGTDYYIWGLQISGIGSLMTGINFFVTIIKMRCKGMTLMKMPIF
TWASLCSVILVVAAFPVLTVTLGLLTLDRYFGTHFFTVSGGGDQMMYVNLIWIWGHPEVYILVLPLFGVFSEVAATFSKK
PLFGYTTMVWASIVITILSFTVWLHHFFTMGASANVNAFFGIMTMIIAIPTGVKIFNWLFTMYKGRITFATPMMWLIGFM
IVFSVGGMTGVLLSVPGVDFQMHNSVFLIAHFHNVIIGGVVFGAFSGLTFWFPKIFGFKLNERLGKYSFWCWFIGFFVAF
MPLYILGTMGMTRRLYHYDAATGYQPLLIVAWVGAMIIGLGILLQIIQIFVSIKQRDQNRVGADAWGYGRTLEWGIPSPV
PFYNFSHDPVVEKRDAYWDHKQKGLNVDNTPVGSAKKYEDINMPKNTAVGVIIGAFSFVFGFAAVWHIWWLAIVGVVGII
GTVLYRSFDYDIDYYVKADQVKEVESRYNQQGELQV
>Mature_676_residues
MLEALIGKLSNPHLVFPYLYEPVSQQLIILTMFIGIVVAGVALLGGITYFRKWGYLWNEWFTTIDHKKIGTMYTIVALVM
MFRGFVDAAMMRTQQALASGDSTGYLIPEHFDQIFSAHGVIMIFFVAMPLIFALMNWVIPLQIGARDVAFPYMNSLSFWL
FVVGAMLINISLLVGDFAHAGWLAYPPFSETTYSPTVGTDYYIWGLQISGIGSLMTGINFFVTIIKMRCKGMTLMKMPIF
TWASLCSVILVVAAFPVLTVTLGLLTLDRYFGTHFFTVSGGGDQMMYVNLIWIWGHPEVYILVLPLFGVFSEVAATFSKK
PLFGYTTMVWASIVITILSFTVWLHHFFTMGASANVNAFFGIMTMIIAIPTGVKIFNWLFTMYKGRITFATPMMWLIGFM
IVFSVGGMTGVLLSVPGVDFQMHNSVFLIAHFHNVIIGGVVFGAFSGLTFWFPKIFGFKLNERLGKYSFWCWFIGFFVAF
MPLYILGTMGMTRRLYHYDAATGYQPLLIVAWVGAMIIGLGILLQIIQIFVSIKQRDQNRVGADAWGYGRTLEWGIPSPV
PFYNFSHDPVVEKRDAYWDHKQKGLNVDNTPVGSAKKYEDINMPKNTAVGVIIGAFSFVFGFAAVWHIWWLAIVGVVGII
GTVLYRSFDYDIDYYVKADQVKEVESRYNQQGELQV

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=520, Percent_Identity=36.9230769230769, Blast_Score=318, Evalue=1e-86,
Organism=Escherichia coli, GI1786634, Length=668, Percent_Identity=63.3233532934132, Blast_Score=867, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=499, Percent_Identity=39.0781563126253, Blast_Score=349, Evalue=7e-97,
Organism=Saccharomyces cerevisiae, GI6226524, Length=322, Percent_Identity=41.6149068322981, Blast_Score=243, Evalue=7e-65,
Organism=Saccharomyces cerevisiae, GI6226523, Length=252, Percent_Identity=34.5238095238095, Blast_Score=133, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 76201; Mature: 76201

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEALIGKLSNPHLVFPYLYEPVSQQLIILTMFIGIVVAGVALLGGITYFRKWGYLWNEW
CCHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTTIDHKKIGTMYTIVALVMMFRGFVDAAMMRTQQALASGDSTGYLIPEHFDQIFSAHGV
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHH
IMIFFVAMPLIFALMNWVIPLQIGARDVAFPYMNSLSFWLFVVGAMLINISLLVGDFAHA
HHHHHHHHHHHHHHHHHHEEHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWLAYPPFSETTYSPTVGTDYYIWGLQISGIGSLMTGINFFVTIIKMRCKGMTLMKMPIF
CCEECCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHH
TWASLCSVILVVAAFPVLTVTLGLLTLDRYFGTHFFTVSGGGDQMMYVNLIWIWGHPEVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEEEEEECCCCEE
ILVLPLFGVFSEVAATFSKKPLFGYTTMVWASIVITILSFTVWLHHFFTMGASANVNAFF
EEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GIMTMIIAIPTGVKIFNWLFTMYKGRITFATPMMWLIGFMIVFSVGGMTGVLLSVPGVDF
HHHHHHHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCHHHHHEECCCCCE
QMHNSVFLIAHFHNVIIGGVVFGAFSGLTFWFPKIFGFKLNERLGKYSFWCWFIGFFVAF
EECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHH
MPLYILGTMGMTRRLYHYDAATGYQPLLIVAWVGAMIIGLGILLQIIQIFVSIKQRDQNR
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGADAWGYGRTLEWGIPSPVPFYNFSHDPVVEKRDAYWDHKQKGLNVDNTPVGSAKKYED
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHCCCCHHHCCCCCCCCCCCCCCCCCC
INMPKNTAVGVIIGAFSFVFGFAAVWHIWWLAIVGVVGIIGTVLYRSFDYDIDYYVKADQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHH
VKEVESRYNQQGELQV
HHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLEALIGKLSNPHLVFPYLYEPVSQQLIILTMFIGIVVAGVALLGGITYFRKWGYLWNEW
CCHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTTIDHKKIGTMYTIVALVMMFRGFVDAAMMRTQQALASGDSTGYLIPEHFDQIFSAHGV
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHH
IMIFFVAMPLIFALMNWVIPLQIGARDVAFPYMNSLSFWLFVVGAMLINISLLVGDFAHA
HHHHHHHHHHHHHHHHHHEEHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWLAYPPFSETTYSPTVGTDYYIWGLQISGIGSLMTGINFFVTIIKMRCKGMTLMKMPIF
CCEECCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHH
TWASLCSVILVVAAFPVLTVTLGLLTLDRYFGTHFFTVSGGGDQMMYVNLIWIWGHPEVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEEEEEECCCCEE
ILVLPLFGVFSEVAATFSKKPLFGYTTMVWASIVITILSFTVWLHHFFTMGASANVNAFF
EEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GIMTMIIAIPTGVKIFNWLFTMYKGRITFATPMMWLIGFMIVFSVGGMTGVLLSVPGVDF
HHHHHHHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCHHHHHEECCCCCE
QMHNSVFLIAHFHNVIIGGVVFGAFSGLTFWFPKIFGFKLNERLGKYSFWCWFIGFFVAF
EECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHH
MPLYILGTMGMTRRLYHYDAATGYQPLLIVAWVGAMIIGLGILLQIIQIFVSIKQRDQNR
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGADAWGYGRTLEWGIPSPVPFYNFSHDPVVEKRDAYWDHKQKGLNVDNTPVGSAKKYED
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHCCCCHHHCCCCCCCCCCCCCCCCCC
INMPKNTAVGVIIGAFSFVFGFAAVWHIWWLAIVGVVGIIGTVLYRSFDYDIDYYVKADQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHH
VKEVESRYNQQGELQV
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]