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The map label for this gene is proP [C]

Identifier: 89255599

GI number: 89255599

Start: 168385

End: 168546

Strand: Reverse

Name: proP [C]

Synonym: FTL_0165

Alternate gene names: 89255599

Gene position: 168546-168385 (Counterclockwise)

Preceding gene: 89255600

Following gene: 89255597

Centisome position: 8.89

GC content: 38.27

Gene sequence:

>162_bases
ATGAAAAAATTATTAGTGCTTTTAGCAAGCTCTGCTGAGTGGTATGAGTTTACAGTGTATTCATTTTGTGCCAGATATAT
TGGAGCGGCATTTTTTCCTGGTGATCCATTTGTTAAGTTTTTAGCAGCTTTTGGAGCTTTTGCAGCCGGGTTTTTAGCGT
GA

Upstream 100 bases:

>100_bases
GCTATTATCAGAAAATAAACTCTAAAAATAATCTAAAAACTGTATTTTTGAGCAAAAATATATTTAAATAAAAATACGGT
ATTTTGAAAATAATCTAACT

Downstream 100 bases:

>100_bases
CCATTGGGAGGTATAATATAGTTAATCCGAAAGATATTTGTAGAAAAAGATATTTGTAGAAATGTTATAATGTCTAATAA
AAATGCCATCATATAGCCAA

Product: dicarboxylate MFS transporter

Products: betaine [Cytoplasm]; Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 53; Mature: 53

Protein sequence:

>53_residues
MKKLLVLLASSAEWYEFTVYSFCARYIGAAFFPGDPFVKFLAAFGAFAAGFLA

Sequences:

>Translated_53_residues
MKKLLVLLASSAEWYEFTVYSFCARYIGAAFFPGDPFVKFLAAFGAFAAGFLA
>Mature_53_residues
MKKLLVLLASSAEWYEFTVYSFCARYIGAAFFPGDPFVKFLAAFGAFAAGFLA

Specific function: Stretch-Inactivated Proline/Betaine Transporter. Prop Is Both An Osmosensor And An Osmoregulator Which Is Available To Participate Early In The Bacterial Osmoregulatory Response. Mediates The Active Accumulation Of Solutes Such As Proline, Glycine Betaine

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 5823; Mature: 5823

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLVLLASSAEWYEFTVYSFCARYIGAAFFPGDPFVKFLAAFGAFAAGFLA
CCHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKLLVLLASSAEWYEFTVYSFCARYIGAAFFPGDPFVKFLAAFGAFAAGFLA
CCHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: betaine [Periplasm]; Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + betaine [Periplasm] = Proton [Cytoplasm] + betaine [Cytoplasm] Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA