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The map label for this gene is lolB [H]

Identifier: 89255587

GI number: 89255587

Start: 157020

End: 157688

Strand: Direct

Name: lolB [H]

Synonym: FTL_0150

Alternate gene names: 89255587

Gene position: 157020-157688 (Clockwise)

Preceding gene: 89255586

Following gene: 89255588

Centisome position: 8.28

GC content: 30.64

Gene sequence:

>669_bases
ATGAAAGACAAATTATTAAAGAAAATGCTGAACACTATGTCAAAGTTAAAAATAGATACAAAGCGCAGATTTAGTTTACT
TATTGCTTTAGTACTAATTATCTCATTATCATCTTGTGCTACAACGCAAACTAATGTTACAGCTATTACAACTAAAACAG
TTTTTAATCAAGAGACTACTTACCATAACTTACTTAAGCTTAAAAAATGGCAAGCCAATGGTTTTATTGGTATTATCTAT
GATAATCAGGCTGAATCTGCTAATTATACATACTTACAAGATGGTGATAATTTTAGTATCAAACTTTATGGTCCATTAGG
AATAGGTAGCATTGAAATAAAAGGCGATACGAACAGTGTTTCACTAGCGAATAGTAAAGGACAAAAGCTAACAGCAAAAG
ACGCTAAAACTTTGATGTTAGAGCAATTAGGCTGGTATGTGCCAGTAGAGGGTCTTAAATACTGGATAAAAGCGATAGCA
ATACCAAATATTAGGCAAACATCCGAACTAAACACCAATAATCTTTTAAGTAAACTATCACAAAATGGTTGGAGTATTAG
TTATAGTAATTATCAACTAGTTGATTCTAAATATCCCTTACCAACAAAGATTAGGATGTCTAGAGATAATCTAACTCTAA
AAATCGTTATAAAATCATGGCAAATATAA

Upstream 100 bases:

>100_bases
TTTCTCGGTGCTGGCAGTTTGGTACCACCAGGAAAAACTCTTGAGTCAGGTTATATGTATTTAGGTTCACCAGCTAAAAA
GGTTAGACCAATAAGTGAGC

Downstream 100 bases:

>100_bases
AAGCTAAAAAATACTATAGTTATGCAAAGATAAATCTATTTTTGCATATATTAAACAAACGTACAGATGGTTACCATAAT
TTACAGACTTGGTTTACCTT

Product: lipoprotein releasing system, subunit B, outer membrane lipoprotein

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKDKLLKKMLNTMSKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTAITTKTVFNQETTYHNLLKLKKWQANGFIGIIY
DNQAESANYTYLQDGDNFSIKLYGPLGIGSIEIKGDTNSVSLANSKGQKLTAKDAKTLMLEQLGWYVPVEGLKYWIKAIA
IPNIRQTSELNTNNLLSKLSQNGWSISYSNYQLVDSKYPLPTKIRMSRDNLTLKIVIKSWQI

Sequences:

>Translated_222_residues
MKDKLLKKMLNTMSKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTAITTKTVFNQETTYHNLLKLKKWQANGFIGIIY
DNQAESANYTYLQDGDNFSIKLYGPLGIGSIEIKGDTNSVSLANSKGQKLTAKDAKTLMLEQLGWYVPVEGLKYWIKAIA
IPNIRQTSELNTNNLLSKLSQNGWSISYSNYQLVDSKYPLPTKIRMSRDNLTLKIVIKSWQI
>Mature_222_residues
MKDKLLKKMLNTMSKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTAITTKTVFNQETTYHNLLKLKKWQANGFIGIIY
DNQAESANYTYLQDGDNFSIKLYGPLGIGSIEIKGDTNSVSLANSKGQKLTAKDAKTLMLEQLGWYVPVEGLKYWIKAIA
IPNIRQTSELNTNNLLSKLSQNGWSISYSNYQLVDSKYPLPTKIRMSRDNLTLKIVIKSWQI

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

Organism=Escherichia coli, GI1787460, Length=203, Percent_Identity=24.1379310344828, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 25092; Mature: 25092

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKLLKKMLNTMSKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTAITTKTVFNQETT
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCH
YHNLLKLKKWQANGFIGIIYDNQAESANYTYLQDGDNFSIKLYGPLGIGSIEIKGDTNSV
HHHHHHHEEECCCCEEEEEECCCCCCCCEEEEECCCCEEEEEEECCCCCEEEEECCCCEE
SLANSKGQKLTAKDAKTLMLEQLGWYVPVEGLKYWIKAIAIPNIRQTSELNTNNLLSKLS
EEECCCCCEEEHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
QNGWSISYSNYQLVDSKYPLPTKIRMSRDNLTLKIVIKSWQI
CCCCEEEECCEEEECCCCCCCCEEEEECCCEEEEEEEEECCC
>Mature Secondary Structure
MKDKLLKKMLNTMSKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTAITTKTVFNQETT
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCH
YHNLLKLKKWQANGFIGIIYDNQAESANYTYLQDGDNFSIKLYGPLGIGSIEIKGDTNSV
HHHHHHHEEECCCCEEEEEECCCCCCCCEEEEECCCCEEEEEEECCCCCEEEEECCCCEE
SLANSKGQKLTAKDAKTLMLEQLGWYVPVEGLKYWIKAIAIPNIRQTSELNTNNLLSKLS
EEECCCCCEEEHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
QNGWSISYSNYQLVDSKYPLPTKIRMSRDNLTLKIVIKSWQI
CCCCEEEECCEEEECCCCCCCCEEEEECCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA