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The map label for this gene is trpA [H]

Identifier: 89255536

GI number: 89255536

Start: 93272

End: 94081

Strand: Reverse

Name: trpA [H]

Synonym: FTL_0098

Alternate gene names: 89255536

Gene position: 94081-93272 (Counterclockwise)

Preceding gene: 89255537

Following gene: 89255534

Centisome position: 4.96

GC content: 35.43

Gene sequence:

>810_bases
ATGACAAATAGATACACAACCCTTTTTGCAAATTTAGAGAAAAGAAATGAAGGAGCTTTTATACCTTTTGTAACAATTGG
TGATCCTAATAAAGCGCTATCCTTTGAAATTATCGATACTTTGGTTAGTTCAGGTGCTGATGCTCTTGAGTTGGGTATAC
CTTTTTCAGATCACTTAGCAGATGGGCCAACAATTCAAGAAGCAAATATTCGCGCTCTGGAGAGTGGAATAACCCCTAAA
GATTGTTTCGATATTCTAACTAAAATAAGAGCAAAATACCCTCATATCCCTATTGGTTTACTACTTTATGCTAATTTAGT
CTATGCAAACGGTATAGAGAACTTTTATCAAAAATGTTTAGATGCAGGTGTTGATTCTATACTTATAGCTGATGTACCCG
CTCACGAATCTAAAGAGTTTCGTGATATTGCTAAAAAAGTTGGTATAGCACAAATATTTATCGCTCCTCCTGATGCTAGT
GAGTCAACTCTTAAGCAAATTTCTAAACTTGGTAGTGGTTATACGTATTTACTATCGAGAGTTGGTGTAACAGGGACAGA
AACTGCTGCAAATATGCCCGTCGAGGATGTATTGGCTAAACTTAGAGAATATAATGCTCCTAAACCAGTTTTAGGCTTTG
GTATCTCTAAACCTGAGCAAGTACAACAAGCTATCAAAGCTGGTGCTGCTGGTGCAATTTCAGGCTCAGCAACAGTGAAA
ATTATTCAAAATAATATCTCTAATAAACAAAAAATGCTTAATGAGCTTACATATTTTGTTAAAGAGATGAAAGCAGCTAC
ATTAAACTAA

Upstream 100 bases:

>100_bases
ATCCTAATAAAGAGCAACTTTTGGTTGTTAATCTATCTGGGCGTGGTGATAAGGATATTTTTACAGTGCATGATATTTTA
AAAGAAAAGGGAGAGATTTA

Downstream 100 bases:

>100_bases
CTAAGCATATTTCAGAGAAAATAATAAATCCTATACAAAACAAACTAACAGAACTTATTTACTACTTTTTTGTAGTTTCT
TTGCGAGTTTATTTCCTAAA

Product: tryptophan synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGIPFSDHLADGPTIQEANIRALESGITPK
DCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCLDAGVDSILIADVPAHESKEFRDIAKKVGIAQIFIAPPDAS
ESTLKQISKLGSGYTYLLSRVGVTGTETAANMPVEDVLAKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVK
IIQNNISNKQKMLNELTYFVKEMKAATLN

Sequences:

>Translated_269_residues
MTNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGIPFSDHLADGPTIQEANIRALESGITPK
DCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCLDAGVDSILIADVPAHESKEFRDIAKKVGIAQIFIAPPDAS
ESTLKQISKLGSGYTYLLSRVGVTGTETAANMPVEDVLAKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVK
IIQNNISNKQKMLNELTYFVKEMKAATLN
>Mature_268_residues
TNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGIPFSDHLADGPTIQEANIRALESGITPKD
CFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCLDAGVDSILIADVPAHESKEFRDIAKKVGIAQIFIAPPDASE
STLKQISKLGSGYTYLLSRVGVTGTETAANMPVEDVLAKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVKI
IQNNISNKQKMLNELTYFVKEMKAATLN

Specific function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate [H]

COG id: COG0159

COG function: function code E; Tryptophan synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpA family [H]

Homologues:

Organism=Escherichia coli, GI1787514, Length=264, Percent_Identity=60.2272727272727, Blast_Score=312, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6321412, Length=251, Percent_Identity=30.2788844621514, Blast_Score=139, Evalue=5e-34,

Paralogues:

None

Copy number: 280 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR018204
- InterPro:   IPR002028 [H]

Pfam domain/function: PF00290 Trp_syntA [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 29078; Mature: 28947

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGIPFSDHLA
CCCCEEEHEEEHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHCC
DGPTIQEANIRALESGITPKDCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCL
CCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DAGVDSILIADVPAHESKEFRDIAKKVGIAQIFIAPPDASESTLKQISKLGSGYTYLLSR
HCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHH
VGVTGTETAANMPVEDVLAKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVK
CCCCCCCHHCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCEEE
IIQNNISNKQKMLNELTYFVKEMKAATLN
EEHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGIPFSDHLA
CCCEEEHEEEHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHCC
DGPTIQEANIRALESGITPKDCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCL
CCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DAGVDSILIADVPAHESKEFRDIAKKVGIAQIFIAPPDASESTLKQISKLGSGYTYLLSR
HCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHH
VGVTGTETAANMPVEDVLAKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVK
CCCCCCCHHCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCEEE
IIQNNISNKQKMLNELTYFVKEMKAATLN
EEHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA