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The map label for this gene is ackA [H]

Identifier: 89255464

GI number: 89255464

Start: 12062

End: 13216

Strand: Direct

Name: ackA [H]

Synonym: FTL_0015

Alternate gene names: 89255464

Gene position: 12062-13216 (Clockwise)

Preceding gene: 89255463

Following gene: 89255465

Centisome position: 0.64

GC content: 34.03

Gene sequence:

>1155_bases
ATGTCTGAAATATTAGTATTAAATTGCGGTAGTTCTTCAGTTAAGTTTGCACTTATAAATCCACATACTTCACAATCTTT
AGTTACAGGTCTTGCAGAAAACATTGCTACTAAAAATTGTAAAGTAGTTTTTAAAGCTGAGCATAAAATTGAAAAGTACC
TTGAGAATGGTAGTTACAAAGATGTATTTGAAATGCTCAAAGATTTTTTGGTAGAGAATAAACATCTAGAAAAGATAGTT
GCAATTGGACATCGGGTAGTTCATGGAGGTCAGTATTTTTCTAAATCGGTACTGATAAATGCTGACTCATTAGAAAAAAT
AAAAGCGTGTATTGCGTTAGCGCCATTGCATAATCCAGCACATATTGAGGGTATAAGATTTTGTCAGCAAATATTTCCAG
AATTACCTCAGGTAGCTGTGTTTGATACAGCATTTCATCAGACTGTGCCAAGCTATATCGCAGAGTATGCAATACCTTAT
GAGCTTACACACAAGCATAATATTCGTAAATATGGCGCACATGGAACTTCACATAAATATGTCTCAGAGCAGGCAGCAAA
GATTTTAACTCAACAAAAAGCTAATGTCATAGTTGCACATTTAGGTAATGGTTGTAGTATTACAGCTGTTGTTGATGGTA
AAAGTATCGATACTAGTATGGGGCTTACTCCTCTAGATGGACTTGTTATGGGAACACGCTCAGGCTGTATTGACCCTAGT
ATTTTTGCATACATATCCGATAATCTTGGTTGGAGTGTCACAGAGATTACAAATATGCTAAACAAGCAAAGTGGTCTATT
AGGTATTTGCGGACATAATGATATGCGCGAAGTTTCTCAACTTGCTGCAAAAGGAGATAGTCTAGCGAAGTTGGCTATAG
AAATCTTCTCTCATAGAGTAGCAAAGTTTGTGGCTAGTTATATGATTTATTTTAATAAGTTAGATGCTTTAGTATTTACA
GGAGGTATTGGTGAGAATGCTGCTAATATCCGTAAAAATATTATTTCAAAGCTAGCAAATCTTGGTTTTATGATAGATCA
TCAAAAAAACTCTAATTCAGAGACATTCATAAACAGCAAAAATAGTCATAATATAATGGTAATAGCGACTAATGAAGAGC
TTATGATTGCTCAAGAAACACAAAATTTAATATAA

Upstream 100 bases:

>100_bases
TGATATAATAAGTATTCTCAAAACACTATACCAAGCTGTCACTATCTTCTAGATTATTATATAATACGGTTATTTCTTAT
TTAAATTTTTTAGTCTAGAT

Downstream 100 bases:

>100_bases
GAGTTTGTTATGAAAAAATCTATATTTATTCTGCCTACTTCAAAACATACCGGTTTACGTTTATTAGCAAGTAGTATGGT
ATATGCATTACAGCAAAAGG

Product: propionate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYKDVFEMLKDFLVENKHLEKIV
AIGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPAHIEGIRFCQQIFPELPQVAVFDTAFHQTVPSYIAEYAIPY
ELTHKHNIRKYGAHGTSHKYVSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPS
IFAYISDNLGWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRVAKFVASYMIYFNKLDALVFT
GGIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSKNSHNIMVIATNEELMIAQETQNLI

Sequences:

>Translated_384_residues
MSEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYKDVFEMLKDFLVENKHLEKIV
AIGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPAHIEGIRFCQQIFPELPQVAVFDTAFHQTVPSYIAEYAIPY
ELTHKHNIRKYGAHGTSHKYVSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPS
IFAYISDNLGWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRVAKFVASYMIYFNKLDALVFT
GGIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSKNSHNIMVIATNEELMIAQETQNLI
>Mature_383_residues
SEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYKDVFEMLKDFLVENKHLEKIVA
IGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPAHIEGIRFCQQIFPELPQVAVFDTAFHQTVPSYIAEYAIPYE
LTHKHNIRKYGAHGTSHKYVSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPSI
FAYISDNLGWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRVAKFVASYMIYFNKLDALVFTG
GIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSKNSHNIMVIATNEELMIAQETQNLI

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=395, Percent_Identity=45.8227848101266, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI145693184, Length=389, Percent_Identity=40.8740359897172, Blast_Score=298, Evalue=3e-82,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 42190; Mature: 42059

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYK
CCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCHH
DVFEMLKDFLVENKHLEKIVAIGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPA
HHHHHHHHHHHCCHHHHHHHHHHHHHEECCHHHCCEEEEECHHHHHHHHHHHHCCCCCCH
HIEGIRFCQQIFPELPQVAVFDTAFHQTVPSYIAEYAIPYELTHKHNIRKYGAHGTSHKY
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCCHHH
VSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPS
HHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCH
IFAYISDNLGWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRV
HEEEEECCCCEEHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
AKFVASYMIYFNKLDALVFTGGIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSK
HHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEECC
NSHNIMVIATNEELMIAQETQNLI
CCCEEEEEEECCCEEEEECCCCCC
>Mature Secondary Structure 
SEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYK
CCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCHH
DVFEMLKDFLVENKHLEKIVAIGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPA
HHHHHHHHHHHCCHHHHHHHHHHHHHEECCHHHCCEEEEECHHHHHHHHHHHHCCCCCCH
HIEGIRFCQQIFPELPQVAVFDTAFHQTVPSYIAEYAIPYELTHKHNIRKYGAHGTSHKY
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCCHHH
VSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPS
HHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCH
IFAYISDNLGWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRV
HEEEEECCCCEEHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
AKFVASYMIYFNKLDALVFTGGIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSK
HHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEECC
NSHNIMVIATNEELMIAQETQNLI
CCCEEEEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA