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The map label for this gene is gntR [H]

Identifier: 89056624

GI number: 89056624

Start: 4242839

End: 4243534

Strand: Direct

Name: gntR [H]

Synonym: Jann_4133

Alternate gene names: 89056624

Gene position: 4242839-4243534 (Clockwise)

Preceding gene: 89056623

Following gene: 89056625

Centisome position: 98.26

GC content: 61.93

Gene sequence:

>696_bases
ATGGCACCCGCAAAGACGGCCTTCGCCGATCCCACACCCCACACCATCGCCCCGATTGAGAACGTACCGCTCCGCGTGCA
GGTGGCAGACCGACTGCGCAATGAGATCCTCAGCGGGCGGATGCGCCCGGGCTCGGGTCTTGTGGAAACGGCGCTGGCCG
AACAGATGAACGTCTCCCGCGCGCCCATTCGCGAGGCGATCCAGATCCTTGAAAATGACGGGTTGGTGGAAACCATTGCC
TACAAGGGCAAGCGCGTGAAACCGCTGACCGCCCGCGAAGTGGCCGAGACCTATAGTCTGCGCGAAGTTTTTGAAGTGAT
GGCCGTGCGGCGTGTCCTGGAAAACAAGGCACCAGTCGACGTGTTGCGCACCCATTGCGACGCCATGAAAGCCGCCGCCG
ATGCCGATGATTTCGCGGCCCTCGTCGCCGCTGACGAAGCCTTCCATCAAGCGCTGATCCGTCTGGCCGATCATGATCTT
CTGCTGGTGTCGTGGAAGAACCTGTACCTGCGCATCCACCAGATCATGGCGCTGCGCAATCGCGACGAGCGCAATCTGCA
TGAGGTCGCCGGAAACCATCCTCCCATCGTCGAGGCGATTGCCGCCGGCGATGCAGATCTGGCGATCAAGCTGATCTCTG
ACCACACCCGCATTCTGGCCGCCTTCGATCCGGCGTCCATCGTGCAGACGACGTAG

Upstream 100 bases:

>100_bases
TTCTAACCACCGCCACCTGTCGCCCGGAATATTGTCCGGGGCGCACCCTCACCGGGGGGCACGTCAGGCTGGTCAGGTTG
TTTCTGGAGGAATATGACGC

Downstream 100 bases:

>100_bases
GCACCGAGGCGCGTCACATGACGCTTTCCGCCCACACCTGGGCCTTCGGTGCAGACCGCAACCCGGACTGGAACCTGACA
TGCAAAAGGTCAGGGCACGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: P28 protein [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MAPAKTAFADPTPHTIAPIENVPLRVQVADRLRNEILSGRMRPGSGLVETALAEQMNVSRAPIREAIQILENDGLVETIA
YKGKRVKPLTAREVAETYSLREVFEVMAVRRVLENKAPVDVLRTHCDAMKAAADADDFAALVAADEAFHQALIRLADHDL
LLVSWKNLYLRIHQIMALRNRDERNLHEVAGNHPPIVEAIAAGDADLAIKLISDHTRILAAFDPASIVQTT

Sequences:

>Translated_231_residues
MAPAKTAFADPTPHTIAPIENVPLRVQVADRLRNEILSGRMRPGSGLVETALAEQMNVSRAPIREAIQILENDGLVETIA
YKGKRVKPLTAREVAETYSLREVFEVMAVRRVLENKAPVDVLRTHCDAMKAAADADDFAALVAADEAFHQALIRLADHDL
LLVSWKNLYLRIHQIMALRNRDERNLHEVAGNHPPIVEAIAAGDADLAIKLISDHTRILAAFDPASIVQTT
>Mature_230_residues
APAKTAFADPTPHTIAPIENVPLRVQVADRLRNEILSGRMRPGSGLVETALAEQMNVSRAPIREAIQILENDGLVETIAY
KGKRVKPLTAREVAETYSLREVFEVMAVRRVLENKAPVDVLRTHCDAMKAAADADDFAALVAADEAFHQALIRLADHDLL
LVSWKNLYLRIHQIMALRNRDERNLHEVAGNHPPIVEAIAAGDADLAIKLISDHTRILAAFDPASIVQTT

Specific function: Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25440; Mature: 25308

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPAKTAFADPTPHTIAPIENVPLRVQVADRLRNEILSGRMRPGSGLVETALAEQMNVSR
CCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCH
APIREAIQILENDGLVETIAYKGKRVKPLTAREVAETYSLREVFEVMAVRRVLENKAPVD
HHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VLRTHCDAMKAAADADDFAALVAADEAFHQALIRLADHDLLLVSWKNLYLRIHQIMALRN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHC
RDERNLHEVAGNHPPIVEAIAAGDADLAIKLISDHTRILAAFDPASIVQTT
CCHHHHHHHCCCCCCHHHHHHCCCHHHEEEEECCCCEEEEECCCHHHHCCC
>Mature Secondary Structure 
APAKTAFADPTPHTIAPIENVPLRVQVADRLRNEILSGRMRPGSGLVETALAEQMNVSR
CCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCH
APIREAIQILENDGLVETIAYKGKRVKPLTAREVAETYSLREVFEVMAVRRVLENKAPVD
HHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VLRTHCDAMKAAADADDFAALVAADEAFHQALIRLADHDLLLVSWKNLYLRIHQIMALRN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHC
RDERNLHEVAGNHPPIVEAIAAGDADLAIKLISDHTRILAAFDPASIVQTT
CCHHHHHHHCCCCCCHHHHHHCCCHHHEEEEECCCCEEEEECCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]