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The map label for this gene is lspA [H]

Identifier: 89056534

GI number: 89056534

Start: 4146719

End: 4147192

Strand: Direct

Name: lspA [H]

Synonym: Jann_4043

Alternate gene names: 89056534

Gene position: 4146719-4147192 (Clockwise)

Preceding gene: 89056533

Following gene: 89056535

Centisome position: 96.03

GC content: 61.6

Gene sequence:

>474_bases
ATGCGGCTTGTGTATCTGAGTGCAGCGTTCTGGTTCCTGATTGATCAGGGGTCGAAATATGGCGTGCTCTACGGCCTCAA
CCTGATCGAGCGGTTGCATATCGAGGTGCTGCCGCCCGTCCTTGTCTTCCACCTCGGCTGGAACACCGGCATCAACTTCG
GCCTTCTCGCGGGCGGGCCAGAGGTGACGCGCTACGGCCTTGTGGTGCTGGCGCTGCTGATCTGCGGATGGCTCTATTAC
TGGGCCAGGACCGGGCTGACGAACCCGCGTGCCTTGCTGTGCGCGGGGGCGGTCATCGGCGGGGCCCTTGGCAACGCGCT
GGACCGCGTGATCCACGGGGCGGTCATCGACTTCCTCAACATGTCGTGCTGTGGGTTCCAGAATCCCTATACCTTCAATA
TTGCCGATATCGGTGTCGTTGTGGGGGCCATCGGGTTGGTGATCTTCGCGGATAGTGAGAAGACCGCCCGCTAG

Upstream 100 bases:

>100_bases
ACGCAGATGTGATCGCTGCCGCCGACGAGGCAGGCCTGGCCATGGTCTTCACCGGCATGCGCCATTTCCGGCACTGATCG
ACACCAAGGAAAGCGACACC

Downstream 100 bases:

>100_bases
CAAAGGCGCAATACCCCCGTGACGGGCGTTTGAAGATGCGCTAGACCGTGCTGCAAGGAGAGTTCGATGGCCATTCGCGC
AACAATTCTGGTTCTGATCA

Product: signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MRLVYLSAAFWFLIDQGSKYGVLYGLNLIERLHIEVLPPVLVFHLGWNTGINFGLLAGGPEVTRYGLVVLALLICGWLYY
WARTGLTNPRALLCAGAVIGGALGNALDRVIHGAVIDFLNMSCCGFQNPYTFNIADIGVVVGAIGLVIFADSEKTAR

Sequences:

>Translated_157_residues
MRLVYLSAAFWFLIDQGSKYGVLYGLNLIERLHIEVLPPVLVFHLGWNTGINFGLLAGGPEVTRYGLVVLALLICGWLYY
WARTGLTNPRALLCAGAVIGGALGNALDRVIHGAVIDFLNMSCCGFQNPYTFNIADIGVVVGAIGLVIFADSEKTAR
>Mature_157_residues
MRLVYLSAAFWFLIDQGSKYGVLYGLNLIERLHIEVLPPVLVFHLGWNTGINFGLLAGGPEVTRYGLVVLALLICGWLYY
WARTGLTNPRALLCAGAVIGGALGNALDRVIHGAVIDFLNMSCCGFQNPYTFNIADIGVVVGAIGLVIFADSEKTAR

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 16988; Mature: 16988

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVYLSAAFWFLIDQGSKYGVLYGLNLIERLHIEVLPPVLVFHLGWNTGINFGLLAGGP
CEEEEEEHEEEEEEECCCCEEEEEHHHHHHHHHHHHCCHHHEEECCCCCCCCEEEEECCH
EVTRYGLVVLALLICGWLYYWARTGLTNPRALLCAGAVIGGALGNALDRVIHGAVIDFLN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MSCCGFQNPYTFNIADIGVVVGAIGLVIFADSEKTAR
CHHCCCCCCEEECHHHHHHHHHHHHHEEEECCCCCCC
>Mature Secondary Structure
MRLVYLSAAFWFLIDQGSKYGVLYGLNLIERLHIEVLPPVLVFHLGWNTGINFGLLAGGP
CEEEEEEHEEEEEEECCCCEEEEEHHHHHHHHHHHHCCHHHEEECCCCCCCCEEEEECCH
EVTRYGLVVLALLICGWLYYWARTGLTNPRALLCAGAVIGGALGNALDRVIHGAVIDFLN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MSCCGFQNPYTFNIADIGVVVGAIGLVIFADSEKTAR
CHHCCCCCCEEECHHHHHHHHHHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA