Click here to switch to the map view.

The map label for this gene is rsmB [H]

Identifier: 89056531

GI number: 89056531

Start: 4142035

End: 4143267

Strand: Direct

Name: rsmB [H]

Synonym: Jann_4040

Alternate gene names: 89056531

Gene position: 4142035-4143267 (Clockwise)

Preceding gene: 89056529

Following gene: 89056532

Centisome position: 95.93

GC content: 64.72

Gene sequence:

>1233_bases
ATGAAAGCGCGCCCCGCCGCCCTTATTCTGCTCAATGCCGTTCTGCGAGAGCGTCAGATTCTGGGTCAGGTGGATGTGCC
TGCAACGGGGGCAGAGGCCGCGCGTGCCAACCGGTTGGCTCTGTCGGTGCTGCGCAATCTGGATGCGGTGGATGCGGTCA
TCAAACCTTACACCACCCGCAAGCCCCAAATCGGTGTGCACAACCTGCTGCGCCTGGGCGCGGTGGAGTTGTTGGTGAAC
GGCGAGGACGCCCATGGTGTCGTCAGTGACATCGTCGGCATTGCCAAGACCCAGCCGCACACGCGCAAGGCTTCGGGCAT
GGTGAACGCGATCCTGCGCAAAATCGCCGTGGAGGGCGCAGAGGCGTTTGCCAAAGCGCCACCGCAACGCCTACCACCGT
GGATCGACAAGGCGCTGCGCAAGCGGATCGGCGCCGATGGCATCCGGGCAATTGAACAGGCGCAGGCGCAGGTGCCACCG
ATGGATCTGACCCCACGCGATGACGGGTTCATGCTGGAGAATGCGGAGGTCCTGCCGACGGGATCTTTGCGGCTGAACAA
CCATCCGCAAGTCAGCGCCCTGCCTGGATACAGTGACGGCGCATTCTGGGTTCAGGACGCTGCCGCCGCCTTGCCCGTGA
AGCTTCTGGGCGATGTGCGGGGCAAGTCTGTGCTGGATCTCTGCGCTGCCCCCGGTGGCAAAACCATGCAATTGGCCGCG
GCGGGCGCAGAGGTCACGGCGCTGGATATCTCGGGCCCGCGCCTGCGCCGGGTGGAGGAAAACCTCGCCCGCACAGGTCT
GTCCGCCACGCTCGTGACCGAGGATGCGTTTCAGCACAGCGGCAGCTACGACGCGATCCTACTGGACGCGCCCTGTTCCG
CCACGGGCACCATCCGCCGCCATCCCGATCTCCCGTTCGTGAAGGATGGCCGGGAGGTCGAGCCGCTGACCAGGCTACAA
ATGCAGCTGATCGACCATGCGCTGACCCTGCTCAAACCCGGCGGGACGCTCGTCTATTGCACCTGCTCGCTGTTGCCGGT
GGAAGGCGAGTTTCAAATCAAAGCGGCCCTCAAACGGCACGATGGGCTTAGCATCATTCCCGCGGACCCGGTCGCACTGG
GTGGGGATGCGGAATGGGCCAGCGCCGAGGGCGGGCTCCGCCTCTGGCCGTTTTATTGGGCGGAGAGAGGTGGGATGGAC
GGCTTCTATATGGCCGCCCTCACGCGGTCATGA

Upstream 100 bases:

>100_bases
GGGGTCAGGTCCTTGGGGGTGCTCATCGCATGGGCCTCCGGCTTGTGTGTCACTCCCACCTGATATACGCGCCGAAGCTC
TTGGAACAAGGAAGCCGTCG

Downstream 100 bases:

>100_bases
TATCCCGCCGCTGACCCCACCAACACGCAGACCCCCCGAATGTCCGAGCCCCTTCCCCCGTCCCCCGCAAGGCCGCGCCC
GCGTGACGGGCTGGCCGCGC

Product: Fmu (Sun)

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKARPAALILLNAVLRERQILGQVDVPATGAEAARANRLALSVLRNLDAVDAVIKPYTTRKPQIGVHNLLRLGAVELLVN
GEDAHGVVSDIVGIAKTQPHTRKASGMVNAILRKIAVEGAEAFAKAPPQRLPPWIDKALRKRIGADGIRAIEQAQAQVPP
MDLTPRDDGFMLENAEVLPTGSLRLNNHPQVSALPGYSDGAFWVQDAAAALPVKLLGDVRGKSVLDLCAAPGGKTMQLAA
AGAEVTALDISGPRLRRVEENLARTGLSATLVTEDAFQHSGSYDAILLDAPCSATGTIRRHPDLPFVKDGREVEPLTRLQ
MQLIDHALTLLKPGGTLVYCTCSLLPVEGEFQIKAALKRHDGLSIIPADPVALGGDAEWASAEGGLRLWPFYWAERGGMD
GFYMAALTRS

Sequences:

>Translated_410_residues
MKARPAALILLNAVLRERQILGQVDVPATGAEAARANRLALSVLRNLDAVDAVIKPYTTRKPQIGVHNLLRLGAVELLVN
GEDAHGVVSDIVGIAKTQPHTRKASGMVNAILRKIAVEGAEAFAKAPPQRLPPWIDKALRKRIGADGIRAIEQAQAQVPP
MDLTPRDDGFMLENAEVLPTGSLRLNNHPQVSALPGYSDGAFWVQDAAAALPVKLLGDVRGKSVLDLCAAPGGKTMQLAA
AGAEVTALDISGPRLRRVEENLARTGLSATLVTEDAFQHSGSYDAILLDAPCSATGTIRRHPDLPFVKDGREVEPLTRLQ
MQLIDHALTLLKPGGTLVYCTCSLLPVEGEFQIKAALKRHDGLSIIPADPVALGGDAEWASAEGGLRLWPFYWAERGGMD
GFYMAALTRS
>Mature_410_residues
MKARPAALILLNAVLRERQILGQVDVPATGAEAARANRLALSVLRNLDAVDAVIKPYTTRKPQIGVHNLLRLGAVELLVN
GEDAHGVVSDIVGIAKTQPHTRKASGMVNAILRKIAVEGAEAFAKAPPQRLPPWIDKALRKRIGADGIRAIEQAQAQVPP
MDLTPRDDGFMLENAEVLPTGSLRLNNHPQVSALPGYSDGAFWVQDAAAALPVKLLGDVRGKSVLDLCAAPGGKTMQLAA
AGAEVTALDISGPRLRRVEENLARTGLSATLVTEDAFQHSGSYDAILLDAPCSATGTIRRHPDLPFVKDGREVEPLTRLQ
MQLIDHALTLLKPGGTLVYCTCSLLPVEGEFQIKAALKRHDGLSIIPADPVALGGDAEWASAEGGLRLWPFYWAERGGMD
GFYMAALTRS

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=234, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI76150623, Length=234, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI32698918, Length=209, Percent_Identity=33.9712918660287, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI40316918, Length=172, Percent_Identity=34.3023255813954, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI270288816, Length=232, Percent_Identity=34.051724137931, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI23199998, Length=232, Percent_Identity=34.051724137931, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI8922322, Length=232, Percent_Identity=34.051724137931, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI270288818, Length=232, Percent_Identity=34.051724137931, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI301336155, Length=181, Percent_Identity=29.2817679558011, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI39995082, Length=181, Percent_Identity=29.2817679558011, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367212, Length=421, Percent_Identity=34.916864608076, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI87081985, Length=259, Percent_Identity=32.046332046332, Blast_Score=102, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17536757, Length=237, Percent_Identity=34.5991561181435, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI25143471, Length=242, Percent_Identity=29.3388429752066, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17509941, Length=179, Percent_Identity=27.3743016759777, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=235, Percent_Identity=31.4893617021277, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319447, Length=231, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI22024126, Length=239, Percent_Identity=30.5439330543933, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355201, Length=189, Percent_Identity=32.8042328042328, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24668781, Length=225, Percent_Identity=30.6666666666667, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356513, Length=225, Percent_Identity=30.6666666666667, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920494, Length=174, Percent_Identity=29.8850574712644, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 43790; Mature: 43790

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKARPAALILLNAVLRERQILGQVDVPATGAEAARANRLALSVLRNLDAVDAVIKPYTTR
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
KPQIGVHNLLRLGAVELLVNGEDAHGVVSDIVGIAKTQPHTRKASGMVNAILRKIAVEGA
CCCCCHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EAFAKAPPQRLPPWIDKALRKRIGADGIRAIEQAQAQVPPMDLTPRDDGFMLENAEVLPT
HHHHCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEECCC
GSLRLNNHPQVSALPGYSDGAFWVQDAAAALPVKLLGDVRGKSVLDLCAAPGGKTMQLAA
CCEEECCCCCEEECCCCCCCCHHHHHHHHHCCHHHHHCCCCCHHHHHHCCCCCCEEEEEE
AGAEVTALDISGPRLRRVEENLARTGLSATLVTEDAFQHSGSYDAILLDAPCSATGTIRR
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCEEEEECCCCCCCCEEE
HPDLPFVKDGREVEPLTRLQMQLIDHALTLLKPGGTLVYCTCSLLPVEGEFQIKAALKRH
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEHHHHHHHC
DGLSIIPADPVALGGDAEWASAEGGLRLWPFYWAERGGMDGFYMAALTRS
CCCEEECCCCEEECCCCCCCCCCCCEEEEEEHHHHCCCCCCEEEEEEECC
>Mature Secondary Structure
MKARPAALILLNAVLRERQILGQVDVPATGAEAARANRLALSVLRNLDAVDAVIKPYTTR
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
KPQIGVHNLLRLGAVELLVNGEDAHGVVSDIVGIAKTQPHTRKASGMVNAILRKIAVEGA
CCCCCHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EAFAKAPPQRLPPWIDKALRKRIGADGIRAIEQAQAQVPPMDLTPRDDGFMLENAEVLPT
HHHHCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEECCC
GSLRLNNHPQVSALPGYSDGAFWVQDAAAALPVKLLGDVRGKSVLDLCAAPGGKTMQLAA
CCEEECCCCCEEECCCCCCCCHHHHHHHHHCCHHHHHCCCCCHHHHHHCCCCCCEEEEEE
AGAEVTALDISGPRLRRVEENLARTGLSATLVTEDAFQHSGSYDAILLDAPCSATGTIRR
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCEEEEECCCCCCCCEEE
HPDLPFVKDGREVEPLTRLQMQLIDHALTLLKPGGTLVYCTCSLLPVEGEFQIKAALKRH
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEHHHHHHHC
DGLSIIPADPVALGGDAEWASAEGGLRLWPFYWAERGGMDGFYMAALTRS
CCCEEECCCCEEECCCCCCCCCCCCEEEEEEHHHHCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA