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The map label for this gene is ubiA

Identifier: 89056404

GI number: 89056404

Start: 4009952

End: 4010908

Strand: Direct

Name: ubiA

Synonym: Jann_3913

Alternate gene names: 89056404

Gene position: 4009952-4010908 (Clockwise)

Preceding gene: 89056399

Following gene: 89056405

Centisome position: 92.87

GC content: 64.16

Gene sequence:

>957_bases
ATGACCGCGCAGGGAAATGGACAAGTCGCAGATGCCGTTCGCGGCAACTGGGTGGATACATTGGCGCCCGAGGCCACACG
ACCCTACCTGCGCCTCAGCCGGGCGGATCGACCCATTGGAACGTGGCTGTTGCTCCTCCCCTGTTGGTGGGGCCTGATGC
TGGCGATTGCCAGCACGCCCGCCACGGCCACGCTGTTTGATGCCTGGATTTTCGTGGGCTGTGCCATCGGGGCCTTCCTG
ATGCGTGGCGCAGGGTGCACCTGGAATGACATCACGGACCGGGACCTCGACGGAGCCGTCACCCGCACCGCCTCGCGGCC
CATCCCGTCGGGCCAGGTCAGCGTCCAAGGCGCGATCATCTGGATGGTCGCCCAGGCGCTCATCTCTCTATTGATCCTTT
TGACGTTCAACTGGACCGCCATCGCTCTTGGCGTGGCCTCCTGCGCGCTGGTCTGCATCTACCCGTTTGCCAAGCGCTTC
ACCTGGTGGCCGCAGGTCTTCCTGGGCCTGGCGTTCAACTGGGGCGCGTTGCTTGCCTGGACCGCCCATACCGGAAGCCT
CTCCCTCGCGCCTGTTCTGCTCTATCTCGGCGGTATCTCCTGGACGCTCTTCTACGACACGATCTACGCCCATCAGGACC
GCGAGGACGATGCGATGATCGGCATCAAATCCACCGCACGGCTGTTTGGCGAGAACACGCGCGTATGGCTGCGCGGGTTC
CTGATCCTCACCCTGTGCCTCATGGGCGCGGGTGTCGCTGTCGCGCTTGTGCCCACAGGGAATTTTCTGGCGCTTGTGGT
TGCGATCCTGGGCGTCTGGGCCATGGGTTGGCACCTGACTTGGCAACTCATGCAGCTGGACATCGACGACGGCGACGCCT
GCCTGAGGCTGTTCCGCTCCAACCGCAACGCGGGCCTGCTGCCCACGCTGTTTTTCGCCGTCGCCGCACTCGTTTGA

Upstream 100 bases:

>100_bases
AGTTCGCATGGTCCCGCGACACGGGAACGCTTTGCGCCTCCCCCAGGGGGTGATCTACAAAGAGGCGGATCTTGGGACGC
TGTGACATGGAAAGATACGT

Downstream 100 bases:

>100_bases
TTGAAAGCGTCTGCGGGACGGGTTACTGAGCTACCATATATAGGCCCCCGAGCAGGGATTTTGCGTAACATCGCCCCATG
ATAGTTCCCAGTCCGAACAA

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MTAQGNGQVADAVRGNWVDTLAPEATRPYLRLSRADRPIGTWLLLLPCWWGLMLAIASTPATATLFDAWIFVGCAIGAFL
MRGAGCTWNDITDRDLDGAVTRTASRPIPSGQVSVQGAIIWMVAQALISLLILLTFNWTAIALGVASCALVCIYPFAKRF
TWWPQVFLGLAFNWGALLAWTAHTGSLSLAPVLLYLGGISWTLFYDTIYAHQDREDDAMIGIKSTARLFGENTRVWLRGF
LILTLCLMGAGVAVALVPTGNFLALVVAILGVWAMGWHLTWQLMQLDIDDGDACLRLFRSNRNAGLLPTLFFAVAALV

Sequences:

>Translated_318_residues
MTAQGNGQVADAVRGNWVDTLAPEATRPYLRLSRADRPIGTWLLLLPCWWGLMLAIASTPATATLFDAWIFVGCAIGAFL
MRGAGCTWNDITDRDLDGAVTRTASRPIPSGQVSVQGAIIWMVAQALISLLILLTFNWTAIALGVASCALVCIYPFAKRF
TWWPQVFLGLAFNWGALLAWTAHTGSLSLAPVLLYLGGISWTLFYDTIYAHQDREDDAMIGIKSTARLFGENTRVWLRGF
LILTLCLMGAGVAVALVPTGNFLALVVAILGVWAMGWHLTWQLMQLDIDDGDACLRLFRSNRNAGLLPTLFFAVAALV
>Mature_317_residues
TAQGNGQVADAVRGNWVDTLAPEATRPYLRLSRADRPIGTWLLLLPCWWGLMLAIASTPATATLFDAWIFVGCAIGAFLM
RGAGCTWNDITDRDLDGAVTRTASRPIPSGQVSVQGAIIWMVAQALISLLILLTFNWTAIALGVASCALVCIYPFAKRFT
WWPQVFLGLAFNWGALLAWTAHTGSLSLAPVLLYLGGISWTLFYDTIYAHQDREDDAMIGIKSTARLFGENTRVWLRGFL
ILTLCLMGAGVAVALVPTGNFLALVVAILGVWAMGWHLTWQLMQLDIDDGDACLRLFRSNRNAGLLPTLFFAVAALV

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=292, Percent_Identity=48.6301369863014, Blast_Score=241, Evalue=6e-64,
Organism=Escherichia coli, GI1790473, Length=296, Percent_Identity=38.5135135135135, Blast_Score=162, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17553718, Length=298, Percent_Identity=45.3020134228188, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI32565247, Length=299, Percent_Identity=42.1404682274247, Blast_Score=194, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17553720, Length=209, Percent_Identity=44.0191387559809, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32565245, Length=148, Percent_Identity=46.6216216216216, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32565243, Length=147, Percent_Identity=46.2585034013605, Blast_Score=117, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6324370, Length=316, Percent_Identity=38.2911392405063, Blast_Score=181, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21355567, Length=295, Percent_Identity=47.7966101694915, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34665; Mature: 34534

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQGNGQVADAVRGNWVDTLAPEATRPYLRLSRADRPIGTWLLLLPCWWGLMLAIASTP
CCCCCCCCCHHHHCCCCHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
ATATLFDAWIFVGCAIGAFLMRGAGCTWNDITDRDLDGAVTRTASRPIPSGQVSVQGAII
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEHHHHH
WMVAQALISLLILLTFNWTAIALGVASCALVCIYPFAKRFTWWPQVFLGLAFNWGALLAW
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
TAHTGSLSLAPVLLYLGGISWTLFYDTIYAHQDREDDAMIGIKSTARLFGENTRVWLRGF
EECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCCHHHHHHH
LILTLCLMGAGVAVALVPTGNFLALVVAILGVWAMGWHLTWQLMQLDIDDGDACLRLFRS
HHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHC
NRNAGLLPTLFFAVAALV
CCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
TAQGNGQVADAVRGNWVDTLAPEATRPYLRLSRADRPIGTWLLLLPCWWGLMLAIASTP
CCCCCCCCHHHHCCCCHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
ATATLFDAWIFVGCAIGAFLMRGAGCTWNDITDRDLDGAVTRTASRPIPSGQVSVQGAII
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEHHHHH
WMVAQALISLLILLTFNWTAIALGVASCALVCIYPFAKRFTWWPQVFLGLAFNWGALLAW
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
TAHTGSLSLAPVLLYLGGISWTLFYDTIYAHQDREDDAMIGIKSTARLFGENTRVWLRGF
EECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCCHHHHHHH
LILTLCLMGAGVAVALVPTGNFLALVVAILGVWAMGWHLTWQLMQLDIDDGDACLRLFRS
HHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHC
NRNAGLLPTLFFAVAALV
CCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA