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The map label for this gene is ywlC [H]

Identifier: 89056386

GI number: 89056386

Start: 3991614

End: 3992558

Strand: Direct

Name: ywlC [H]

Synonym: Jann_3895

Alternate gene names: 89056386

Gene position: 3991614-3992558 (Clockwise)

Preceding gene: 89056382

Following gene: 89056388

Centisome position: 92.44

GC content: 68.78

Gene sequence:

>945_bases
ATGCCACGTCCTCAGCCAGAAATGTTGCACAATGATGTCGCGGGGATCGCCCGCGCGGCCGAGGTTTTGCGAGATGGCGG
GCTGTTAGCCCTGCCGACGGAGACCGTCTATGGCCTCGCCGCCGATGCAAGGAACGGCGCGGCGGTGGCCCGGATCTTTG
CGGCAAAGGGGCGACCCACGTTCAACCCGCTGATTGTGCATGTTGTGTCGCTGGAGACGGCGGAAGAGTTGGTCGAGGTC
AACGCGCAAGCCCACGCGCTGGCGAAGGCCTTCTGGCCCGGTCCGATGACGCTGGTCCTGCCCTCGAAAGGTCGGGTGGC
GGATCTGATCTCGGGCGGATTGGACACGCTGGCGGTCCGCGTGCCCGCCCACCCCTTGGCCCGCGCTGTGCTGGGTGCGT
TCGGAGGCCCGGTGGCCGCCCCCTCGGCCAATCCGTCCGGGCAGATCAGCCCGACAATGGCCGCGCATGTCGTGGCTGGC
CTTGGCAGCGCCGTGGAAGCAGTGCTCGACGGCGGGGCCTGTGGCGTGGGATTGGAGTCAACAATCCTTGCGCCCTCGGA
AGGAGGCGTGCGGTTGTTGCGCGAAGGTGGCGTGTCGCGCGAGGCGGTGGAGGCCGTCGTTGGCCCGGTCGTTGCGGACC
TGACGCCGGGGCGGATCGAAGCTCCGGGCCAGATGGAGCGGCACTACGCGCCGCGCACGCAGGTGGTTCTGGGAAGTGTT
GCCACGCCGGGCGATGTGATGATCGGGTTCGGAGCTGTGGGCGGTGATTTCACGCTCTCCGAGCGGGGCGACCTCGTTGA
GGCCGCCGAGCGGCTGTTCGCTACGCTCCACGCCGCGGACACTTTGGCTTTGACGCGGGGGGCGCAGGTGATCCGTGTGG
CAGAGGTGCCGGAGGTGGGTCTGGGCCGGGCCATCAATGACCGTTTGCGGCGCGCGGCGCGCTAG

Upstream 100 bases:

>100_bases
GATTTGCGCGGGCGGTCGTTTCGCGCTAGGGCCGTGATCGTGTTGGGGCGCATCATGGGGCCCCGGTAAATGGTTCAGCA
ACTTCAACGTTACGTCACAG

Downstream 100 bases:

>100_bases
GCATGATCGCCTAAGCGTGTCCGGCCTCCGATGAGAGCATCAGCGGATCGAAGCCAAGGCTTTGCACGGCGGCGTCCCAT
TTCCGCTCCATCTTGTGGTC

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPRPQPEMLHNDVAGIARAAEVLRDGGLLALPTETVYGLAADARNGAAVARIFAAKGRPTFNPLIVHVVSLETAEELVEV
NAQAHALAKAFWPGPMTLVLPSKGRVADLISGGLDTLAVRVPAHPLARAVLGAFGGPVAAPSANPSGQISPTMAAHVVAG
LGSAVEAVLDGGACGVGLESTILAPSEGGVRLLREGGVSREAVEAVVGPVVADLTPGRIEAPGQMERHYAPRTQVVLGSV
ATPGDVMIGFGAVGGDFTLSERGDLVEAAERLFATLHAADTLALTRGAQVIRVAEVPEVGLGRAINDRLRRAAR

Sequences:

>Translated_314_residues
MPRPQPEMLHNDVAGIARAAEVLRDGGLLALPTETVYGLAADARNGAAVARIFAAKGRPTFNPLIVHVVSLETAEELVEV
NAQAHALAKAFWPGPMTLVLPSKGRVADLISGGLDTLAVRVPAHPLARAVLGAFGGPVAAPSANPSGQISPTMAAHVVAG
LGSAVEAVLDGGACGVGLESTILAPSEGGVRLLREGGVSREAVEAVVGPVVADLTPGRIEAPGQMERHYAPRTQVVLGSV
ATPGDVMIGFGAVGGDFTLSERGDLVEAAERLFATLHAADTLALTRGAQVIRVAEVPEVGLGRAINDRLRRAAR
>Mature_313_residues
PRPQPEMLHNDVAGIARAAEVLRDGGLLALPTETVYGLAADARNGAAVARIFAAKGRPTFNPLIVHVVSLETAEELVEVN
AQAHALAKAFWPGPMTLVLPSKGRVADLISGGLDTLAVRVPAHPLARAVLGAFGGPVAAPSANPSGQISPTMAAHVVAGL
GSAVEAVLDGGACGVGLESTILAPSEGGVRLLREGGVSREAVEAVVGPVVADLTPGRIEAPGQMERHYAPRTQVVLGSVA
TPGDVMIGFGAVGGDFTLSERGDLVEAAERLFATLHAADTLALTRGAQVIRVAEVPEVGLGRAINDRLRRAAR

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=157, Percent_Identity=33.7579617834395, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17537239, Length=194, Percent_Identity=31.9587628865979, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321269, Length=261, Percent_Identity=36.7816091954023, Blast_Score=150, Evalue=3e-37,
Organism=Drosophila melanogaster, GI78707274, Length=170, Percent_Identity=27.6470588235294, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 32071; Mature: 31940

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPQPEMLHNDVAGIARAAEVLRDGGLLALPTETVYGLAADARNGAAVARIFAAKGRPT
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCHHHHHHHHHCCCCC
FNPLIVHVVSLETAEELVEVNAQAHALAKAFWPGPMTLVLPSKGRVADLISGGLDTLAVR
CCHHEEEEEHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCHHHEEEE
VPAHPLARAVLGAFGGPVAAPSANPSGQISPTMAAHVVAGLGSAVEAVLDGGACGVGLES
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TILAPSEGGVRLLREGGVSREAVEAVVGPVVADLTPGRIEAPGQMERHYAPRTQVVLGSV
EEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEEECC
ATPGDVMIGFGAVGGDFTLSERGDLVEAAERLFATLHAADTLALTRGAQVIRVAEVPEVG
CCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
LGRAINDRLRRAAR
CCHHHHHHHHHHCC
>Mature Secondary Structure 
PRPQPEMLHNDVAGIARAAEVLRDGGLLALPTETVYGLAADARNGAAVARIFAAKGRPT
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCCCHHHHHHHHHCCCCC
FNPLIVHVVSLETAEELVEVNAQAHALAKAFWPGPMTLVLPSKGRVADLISGGLDTLAVR
CCHHEEEEEHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCHHHEEEE
VPAHPLARAVLGAFGGPVAAPSANPSGQISPTMAAHVVAGLGSAVEAVLDGGACGVGLES
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TILAPSEGGVRLLREGGVSREAVEAVVGPVVADLTPGRIEAPGQMERHYAPRTQVVLGSV
EEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEEECC
ATPGDVMIGFGAVGGDFTLSERGDLVEAAERLFATLHAADTLALTRGAQVIRVAEVPEVG
CCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
LGRAINDRLRRAAR
CCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]