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The map label for this gene is dnaX [H]

Identifier: 89056367

GI number: 89056367

Start: 3974827

End: 3976581

Strand: Direct

Name: dnaX [H]

Synonym: Jann_3876

Alternate gene names: 89056367

Gene position: 3974827-3976581 (Clockwise)

Preceding gene: 89056366

Following gene: 89056368

Centisome position: 92.05

GC content: 63.87

Gene sequence:

>1755_bases
ATGACCGAGACCCCTGATACTGGCTACCAAGTCCTTGCGCGAAAGTACCGCCCCGCGACCTTTGCCGATCTGATCGGGCA
AGAGGCGATGGTCCGCACGCTGAAGAACGCCTTCGATGCGGATCGGATTGCCCAAGCCTTCATGCTGACGGGTATCCGGG
GCACGGGCAAGACCACGACCGCGCGGATCATCGCAAAGGGGTTGAACTGCATCGGAGCGGACGGAGAAGGCGGCCCGACG
ACGGACCCGTGCGGTGTATGCCAGAACTGCGTGGCGATCACCGAAGGCCGCCATGTCGACGTAATGGAGATGGACGCGGC
CTCCAATACCGGCGTGCAGAACATCCGCGATGCGATCATTGAAACGGTGAGCTACCGCGCAGCCCAGGCGCGCTACAAGA
TCTTCATCATCGACGAAGTTCACATGCTGTCGACGTCCGCCTTCAACGCCCTGTTGAAAACGCTGGAAGAACCGCCCGCC
CACGTGAAGTTCCTGTTTGCCACGACCGAGATCCGCAAGGTTCCCGTCACGGTCCTGTCGCGCTGCCAAAGGTTTGACCT
GCGCCGGATCGAGCCTGAGGTGATGATCGCCCATCTGCAACGCATCGCCGGGCTGGAAAGCGCGGAAATCGCGGAGGATG
CCGTGGCGCTGATCACACGGGCCGCCGAAGGCTCCGTCCGTGATGCGATGTCGCTTCTGGATCAGGCGATTGCCCATGGT
GCCGGGGAAACGACGGCCGATCAGGTGCGTGCGATGTTGGGCCTGGCGGATCGGGGCCGGGTGATGGATCTTTTTGAGGC
GATCATGGCCGGCGAAGCCGCGACAGCTTTGGACGAGTTGAGTGCGCAATATGCCGATGGCGCGGATCCCGTTGCGGTCC
TGCGTGACCTGGCCGAGATCACCCATTGGCTGAGCGTTATTTCCATCACGCCCGATGCGGCAGAAGACCCGACCATATCC
CCTGATGAACGCACCCGCGGGTTGGTCCTGGCCGAAAAACTGCCGATGCGCGTGCTGACGCGGATGTGGCAGATGCTGCT
GAAAGCGCTGGAAGAGGTCGCCATGGCCCCCAACGCGATGATGGCTGCAGAAATGGCCGTGATCCGCCTGACCCATGTGG
CCGATCTGCCGACGCCCGGGGATCTGGTAAAGAAGCTGGCCGAGACGCCCCGCCCGGCTGGTGGTCCGCCCTCTGGCGGT
GTCGGGGGCGGCGTGTCAGGTCCCGCGCCACAGGCCCGGGCTACGGGGGGCGCGCCGCTTGGTGGCGGCGGTCCTCAGGC
GGCCTTGGCGCCCCAGACCGGGCCAGACCTATCGGTCTACCCAACGTTCGAATCGGTCGTGGCCTTGGTTGAAGGCGCAC
GCGATATCAAGCTGTTGATTGAGGTGAAGACGTGCTTGCGACTGGTCTCCTACGCGCCCGGCCGGCTGGAGGTCGAGGTG
ACGGACACGGCACCGCGCGATCTGATCCCGCGTTTGGGGCGGATGTTGCACACGGCAACCGGCGCGCGCTGGGGCATATC
AGTCGCATCATCTGGTGGCACGACAACGATTCAAGAGCAGGAACAAGCCGCGCAGAAAGAGGCGGAAGCCGAGGTCACGC
AGCATCCGCTGATGCAGGCCGTCCTGTCACGTTTCCCCAAGGCCCGCATTGCCGAGATCAGAAGCCATGCGGCGCTGGAG
CAGGAGGCTGCGGCCACAGCGCTGGAAGAAATTCCGGAAGAGGCCGATGACTGGGATCCGTTCGAGGACGAGTAG

Upstream 100 bases:

>100_bases
TCGGCTCCATTCTGACCGGCGCGATTCTTTGGCTGCTGTAATCCGGTGGACGGCGCGGGGGCAGAGGCCTAGTTTGACCT
CGGCAATTGCGTGAGGCGAC

Downstream 100 bases:

>100_bases
GTTCTATTCCACAGGATACAGCGCTTGGCACCGCGTGAGCGCGAGAGGCTTGCCGCAGACACCGCCACAGCCTACCTGTG
AGCAAACGCAAATCGGATGG

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MTETPDTGYQVLARKYRPATFADLIGQEAMVRTLKNAFDADRIAQAFMLTGIRGTGKTTTARIIAKGLNCIGADGEGGPT
TDPCGVCQNCVAITEGRHVDVMEMDAASNTGVQNIRDAIIETVSYRAAQARYKIFIIDEVHMLSTSAFNALLKTLEEPPA
HVKFLFATTEIRKVPVTVLSRCQRFDLRRIEPEVMIAHLQRIAGLESAEIAEDAVALITRAAEGSVRDAMSLLDQAIAHG
AGETTADQVRAMLGLADRGRVMDLFEAIMAGEAATALDELSAQYADGADPVAVLRDLAEITHWLSVISITPDAAEDPTIS
PDERTRGLVLAEKLPMRVLTRMWQMLLKALEEVAMAPNAMMAAEMAVIRLTHVADLPTPGDLVKKLAETPRPAGGPPSGG
VGGGVSGPAPQARATGGAPLGGGGPQAALAPQTGPDLSVYPTFESVVALVEGARDIKLLIEVKTCLRLVSYAPGRLEVEV
TDTAPRDLIPRLGRMLHTATGARWGISVASSGGTTTIQEQEQAAQKEAEAEVTQHPLMQAVLSRFPKARIAEIRSHAALE
QEAAATALEEIPEEADDWDPFEDE

Sequences:

>Translated_584_residues
MTETPDTGYQVLARKYRPATFADLIGQEAMVRTLKNAFDADRIAQAFMLTGIRGTGKTTTARIIAKGLNCIGADGEGGPT
TDPCGVCQNCVAITEGRHVDVMEMDAASNTGVQNIRDAIIETVSYRAAQARYKIFIIDEVHMLSTSAFNALLKTLEEPPA
HVKFLFATTEIRKVPVTVLSRCQRFDLRRIEPEVMIAHLQRIAGLESAEIAEDAVALITRAAEGSVRDAMSLLDQAIAHG
AGETTADQVRAMLGLADRGRVMDLFEAIMAGEAATALDELSAQYADGADPVAVLRDLAEITHWLSVISITPDAAEDPTIS
PDERTRGLVLAEKLPMRVLTRMWQMLLKALEEVAMAPNAMMAAEMAVIRLTHVADLPTPGDLVKKLAETPRPAGGPPSGG
VGGGVSGPAPQARATGGAPLGGGGPQAALAPQTGPDLSVYPTFESVVALVEGARDIKLLIEVKTCLRLVSYAPGRLEVEV
TDTAPRDLIPRLGRMLHTATGARWGISVASSGGTTTIQEQEQAAQKEAEAEVTQHPLMQAVLSRFPKARIAEIRSHAALE
QEAAATALEEIPEEADDWDPFEDE
>Mature_583_residues
TETPDTGYQVLARKYRPATFADLIGQEAMVRTLKNAFDADRIAQAFMLTGIRGTGKTTTARIIAKGLNCIGADGEGGPTT
DPCGVCQNCVAITEGRHVDVMEMDAASNTGVQNIRDAIIETVSYRAAQARYKIFIIDEVHMLSTSAFNALLKTLEEPPAH
VKFLFATTEIRKVPVTVLSRCQRFDLRRIEPEVMIAHLQRIAGLESAEIAEDAVALITRAAEGSVRDAMSLLDQAIAHGA
GETTADQVRAMLGLADRGRVMDLFEAIMAGEAATALDELSAQYADGADPVAVLRDLAEITHWLSVISITPDAAEDPTISP
DERTRGLVLAEKLPMRVLTRMWQMLLKALEEVAMAPNAMMAAEMAVIRLTHVADLPTPGDLVKKLAETPRPAGGPPSGGV
GGGVSGPAPQARATGGAPLGGGGPQAALAPQTGPDLSVYPTFESVVALVEGARDIKLLIEVKTCLRLVSYAPGRLEVEVT
DTAPRDLIPRLGRMLHTATGARWGISVASSGGTTTIQEQEQAAQKEAEAEVTQHPLMQAVLSRFPKARIAEIRSHAALEQ
EAAATALEEIPEEADDWDPFEDE

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=268, Percent_Identity=25.7462686567164, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI194306571, Length=271, Percent_Identity=25.4612546125461, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI194306567, Length=271, Percent_Identity=25.4612546125461, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4506491, Length=284, Percent_Identity=23.5915492957746, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI31881687, Length=284, Percent_Identity=23.5915492957746, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI194306569, Length=182, Percent_Identity=24.1758241758242, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1786676, Length=390, Percent_Identity=42.0512820512821, Blast_Score=295, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI71986063, Length=317, Percent_Identity=20.5047318611987, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324478, Length=237, Percent_Identity=24.8945147679325, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI19921076, Length=278, Percent_Identity=24.8201438848921, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17647857, Length=294, Percent_Identity=22.108843537415, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 62314; Mature: 62183

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETPDTGYQVLARKYRPATFADLIGQEAMVRTLKNAFDADRIAQAFMLTGIRGTGKTTT
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHH
ARIIAKGLNCIGADGEGGPTTDPCGVCQNCVAITEGRHVDVMEMDAASNTGVQNIRDAII
HHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
ETVSYRAAQARYKIFIIDEVHMLSTSAFNALLKTLEEPPAHVKFLFATTEIRKVPVTVLS
HHHHHHHHHCEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHH
RCQRFDLRRIEPEVMIAHLQRIAGLESAEIAEDAVALITRAAEGSVRDAMSLLDQAIAHG
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
AGETTADQVRAMLGLADRGRVMDLFEAIMAGEAATALDELSAQYADGADPVAVLRDLAEI
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
THWLSVISITPDAAEDPTISPDERTRGLVLAEKLPMRVLTRMWQMLLKALEEVAMAPNAM
HHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHH
MAAEMAVIRLTHVADLPTPGDLVKKLAETPRPAGGPPSGGVGGGVSGPAPQARATGGAPL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGGGPQAALAPQTGPDLSVYPTFESVVALVEGARDIKLLIEVKTCLRLVSYAPGRLEVEV
CCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
TDTAPRDLIPRLGRMLHTATGARWGISVASSGGTTTIQEQEQAAQKEAEAEVTQHPLMQA
CCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLSRFPKARIAEIRSHAALEQEAAATALEEIPEEADDWDPFEDE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TETPDTGYQVLARKYRPATFADLIGQEAMVRTLKNAFDADRIAQAFMLTGIRGTGKTTT
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHH
ARIIAKGLNCIGADGEGGPTTDPCGVCQNCVAITEGRHVDVMEMDAASNTGVQNIRDAII
HHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
ETVSYRAAQARYKIFIIDEVHMLSTSAFNALLKTLEEPPAHVKFLFATTEIRKVPVTVLS
HHHHHHHHHCEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHH
RCQRFDLRRIEPEVMIAHLQRIAGLESAEIAEDAVALITRAAEGSVRDAMSLLDQAIAHG
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
AGETTADQVRAMLGLADRGRVMDLFEAIMAGEAATALDELSAQYADGADPVAVLRDLAEI
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
THWLSVISITPDAAEDPTISPDERTRGLVLAEKLPMRVLTRMWQMLLKALEEVAMAPNAM
HHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHH
MAAEMAVIRLTHVADLPTPGDLVKKLAETPRPAGGPPSGGVGGGVSGPAPQARATGGAPL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGGGPQAALAPQTGPDLSVYPTFESVVALVEGARDIKLLIEVKTCLRLVSYAPGRLEVEV
CCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
TDTAPRDLIPRLGRMLHTATGARWGISVASSGGTTTIQEQEQAAQKEAEAEVTQHPLMQA
CCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLSRFPKARIAEIRSHAALEQEAAATALEEIPEEADDWDPFEDE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]