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The map label for this gene is yngJ [H]

Identifier: 89056313

GI number: 89056313

Start: 3913581

End: 3914741

Strand: Direct

Name: yngJ [H]

Synonym: Jann_3822

Alternate gene names: 89056313

Gene position: 3913581-3914741 (Clockwise)

Preceding gene: 89056310

Following gene: 89056314

Centisome position: 90.63

GC content: 61.33

Gene sequence:

>1161_bases
ATGGATTTTGGCCTCAGCGAAGAGCAGGAGATGATCGTCTCCACCGTCCGCAGTTTCGTGGAAAACGAGATCTATCCCCA
TGAGGCCGAGGTCGAACGCAGCGGACATATGCCGCTGGAGCTGGGTCAGGAGATCAAGCAGAAGGTGATCGACCTGGGCT
TTTATGCCTGCAATTTCCCGGAAAGCGTCGGCGGCGCAGGTCTCAGCCACCTTGATTTCACGCTGGTGGAGCGGGAATTG
GGGCGCGGCTCCATGGCGCTGACACATTTCTTCGGGCGGCCCCAGAATATCCTGATGGCCTGCGACGGGGAACAGGTGGA
GAAGTACCTGCTCCCCGCCGTGCGCGGAGAGCGGATGGATGCCCTTGCCATGACCGAACCCGATGCAGGATCCGACGTCC
GCGGCATGAAATGCAACGCCGTGCGGGATGGGGGCGATTGGGTGGTCAACGGCTCCAAACACTTCATCTCGGGCGCGGAG
CACGCCGATTTCTTCATCGTCTTCGTGGCCACGGGCGTCGATGAGACACCCAAGGGCCCAAAGAAGCGGATCACCTGTTT
CCTCGTGGACCGCGGTCACGGGGGTTTTGAGGTGCGCGACGGGTACAATTCCGTCAGCCACCGGGGTTACAAAAACCGCA
TCCTGGAATTTAACGACTGCCGCCTGCCCGATGGCCAAGTGTTGGGAGAGGTCGACGGCGGTTTTGCGGTGATGAACGAA
TGGCTCTACGCCACGCGCCTGACGGTGGCCGCCTTCAGCGTCGGCCGCGCCCGGCGGTGTTTTGACATGGCTGTAGACTA
TGCCGCGCAGCGCAAGCAATTCGGGCAGGCGATTGCGAAGTTCCAGGGCGTCAGTTTCCAGATCGCCGACATGATCACCG
AAATTGACGCCGCCGATCACCTGACGCTGGCCGGGGCATGGCGATTGGACAAGGGCCTGCCCGCGAACCGCGAAATCGCC
TCGGCCAAGCTCTACGCGACCGAGATGCTGGCGCGGGTCACCGATACGACGTTGCAGATTTTCGGCGGCATGGGATTGAT
GGATGACTTCCCCATTGAACGCTTCTGGCGCGATGCGCGGGTCGAACGGATCTGGGACGGAACCTCGGAAATCCAGCGCC
ACATCATTAGCCGGGATCTGTTCCGGCCTTTGGGCGCATGA

Upstream 100 bases:

>100_bases
GCAACATGGAAAACGTATCCGGCATGATCTCAACGCATACAGCAAGATGGTGCATCGCACGAGGCCTAACGCTTGCCCCA
TAGGCGGGAGGAAGACGAGT

Downstream 100 bases:

>100_bases
GCGCTGAGCAGGGTGAATAGGGTACGATGACCGCGGGATCGGATCTGGACAGACTCTTGCGCCCCAGCTCAATCGCCGTG
ATTGGCGGCGGGGCGTGGTG

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MDFGLSEEQEMIVSTVRSFVENEIYPHEAEVERSGHMPLELGQEIKQKVIDLGFYACNFPESVGGAGLSHLDFTLVEREL
GRGSMALTHFFGRPQNILMACDGEQVEKYLLPAVRGERMDALAMTEPDAGSDVRGMKCNAVRDGGDWVVNGSKHFISGAE
HADFFIVFVATGVDETPKGPKKRITCFLVDRGHGGFEVRDGYNSVSHRGYKNRILEFNDCRLPDGQVLGEVDGGFAVMNE
WLYATRLTVAAFSVGRARRCFDMAVDYAAQRKQFGQAIAKFQGVSFQIADMITEIDAADHLTLAGAWRLDKGLPANREIA
SAKLYATEMLARVTDTTLQIFGGMGLMDDFPIERFWRDARVERIWDGTSEIQRHIISRDLFRPLGA

Sequences:

>Translated_386_residues
MDFGLSEEQEMIVSTVRSFVENEIYPHEAEVERSGHMPLELGQEIKQKVIDLGFYACNFPESVGGAGLSHLDFTLVEREL
GRGSMALTHFFGRPQNILMACDGEQVEKYLLPAVRGERMDALAMTEPDAGSDVRGMKCNAVRDGGDWVVNGSKHFISGAE
HADFFIVFVATGVDETPKGPKKRITCFLVDRGHGGFEVRDGYNSVSHRGYKNRILEFNDCRLPDGQVLGEVDGGFAVMNE
WLYATRLTVAAFSVGRARRCFDMAVDYAAQRKQFGQAIAKFQGVSFQIADMITEIDAADHLTLAGAWRLDKGLPANREIA
SAKLYATEMLARVTDTTLQIFGGMGLMDDFPIERFWRDARVERIWDGTSEIQRHIISRDLFRPLGA
>Mature_386_residues
MDFGLSEEQEMIVSTVRSFVENEIYPHEAEVERSGHMPLELGQEIKQKVIDLGFYACNFPESVGGAGLSHLDFTLVEREL
GRGSMALTHFFGRPQNILMACDGEQVEKYLLPAVRGERMDALAMTEPDAGSDVRGMKCNAVRDGGDWVVNGSKHFISGAE
HADFFIVFVATGVDETPKGPKKRITCFLVDRGHGGFEVRDGYNSVSHRGYKNRILEFNDCRLPDGQVLGEVDGGFAVMNE
WLYATRLTVAAFSVGRARRCFDMAVDYAAQRKQFGQAIAKFQGVSFQIADMITEIDAADHLTLAGAWRLDKGLPANREIA
SAKLYATEMLARVTDTTLQIFGGMGLMDDFPIERFWRDARVERIWDGTSEIQRHIISRDLFRPLGA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=384, Percent_Identity=34.375, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI226958412, Length=380, Percent_Identity=33.4210526315789, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=32.1148825065274, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=32.1148825065274, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI4501859, Length=381, Percent_Identity=31.2335958005249, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=34.0175953079179, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI4501857, Length=386, Percent_Identity=32.3834196891192, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI7656849, Length=386, Percent_Identity=30.3108808290155, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI21361497, Length=356, Percent_Identity=30.3370786516854, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI4557235, Length=387, Percent_Identity=32.2997416020672, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI76496475, Length=387, Percent_Identity=32.2997416020672, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI38505218, Length=403, Percent_Identity=26.302729528536, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI4503943, Length=386, Percent_Identity=23.8341968911917, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI7669494, Length=360, Percent_Identity=24.1666666666667, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI48976061, Length=405, Percent_Identity=23.9506172839506, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI211971008, Length=405, Percent_Identity=23.9506172839506, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786223, Length=386, Percent_Identity=29.2746113989637, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87081958, Length=387, Percent_Identity=29.9741602067183, Blast_Score=156, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17534899, Length=387, Percent_Identity=35.6589147286822, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17508101, Length=380, Percent_Identity=36.0526315789474, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17569725, Length=386, Percent_Identity=33.160621761658, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17570075, Length=386, Percent_Identity=32.9015544041451, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17538396, Length=386, Percent_Identity=32.3834196891192, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17533517, Length=384, Percent_Identity=31.25, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17506239, Length=379, Percent_Identity=30.8707124010554, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71990804, Length=293, Percent_Identity=34.4709897610922, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71985184, Length=335, Percent_Identity=28.0597014925373, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17505929, Length=367, Percent_Identity=27.7929155313352, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17551932, Length=372, Percent_Identity=27.1505376344086, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71982178, Length=283, Percent_Identity=29.6819787985866, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=30.4526748971193, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32563615, Length=233, Percent_Identity=30.0429184549356, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71985192, Length=270, Percent_Identity=26.2962962962963, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=390, Percent_Identity=23.3333333333333, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=399, Percent_Identity=26.3157894736842, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17531913, Length=164, Percent_Identity=29.2682926829268, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24660351, Length=385, Percent_Identity=34.025974025974, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI21356377, Length=383, Percent_Identity=32.8981723237598, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24646207, Length=385, Percent_Identity=32.2077922077922, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI21355753, Length=386, Percent_Identity=33.6787564766839, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=30.3430079155673, Blast_Score=184, Evalue=9e-47,
Organism=Drosophila melanogaster, GI281363737, Length=337, Percent_Identity=32.3442136498516, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19920834, Length=390, Percent_Identity=26.1538461538462, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43036; Mature: 43036

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFGLSEEQEMIVSTVRSFVENEIYPHEAEVERSGHMPLELGQEIKQKVIDLGFYACNFP
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHEECCC
ESVGGAGLSHLDFTLVERELGRGSMALTHFFGRPQNILMACDGEQVEKYLLPAVRGERMD
HHHCCCCCHHHHHHHHHHHHCCCCEEHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCC
ALAMTEPDAGSDVRGMKCNAVRDGGDWVVNGSKHFISGAEHADFFIVFVATGVDETPKGP
EEEECCCCCCCCCCCCEECEEECCCCEEECCCHHHCCCCCCCCEEEEEEEECCCCCCCCC
KKRITCFLVDRGHGGFEVRDGYNSVSHRGYKNRILEFNDCRLPDGQVLGEVDGGFAVMNE
CCEEEEEEEECCCCCEEEECCCCHHHCCCHHHCCEEECCCCCCCCCEEECCCCCHHHHHH
WLYATRLTVAAFSVGRARRCFDMAVDYAAQRKQFGQAIAKFQGVSFQIADMITEIDAADH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCC
LTLAGAWRLDKGLPANREIASAKLYATEMLARVTDTTLQIFGGMGLMDDFPIERFWRDAR
EEEEECEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VERIWDGTSEIQRHIISRDLFRPLGA
HHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFGLSEEQEMIVSTVRSFVENEIYPHEAEVERSGHMPLELGQEIKQKVIDLGFYACNFP
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHEECCC
ESVGGAGLSHLDFTLVERELGRGSMALTHFFGRPQNILMACDGEQVEKYLLPAVRGERMD
HHHCCCCCHHHHHHHHHHHHCCCCEEHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCC
ALAMTEPDAGSDVRGMKCNAVRDGGDWVVNGSKHFISGAEHADFFIVFVATGVDETPKGP
EEEECCCCCCCCCCCCEECEEECCCCEEECCCHHHCCCCCCCCEEEEEEEECCCCCCCCC
KKRITCFLVDRGHGGFEVRDGYNSVSHRGYKNRILEFNDCRLPDGQVLGEVDGGFAVMNE
CCEEEEEEEECCCCCEEEECCCCHHHCCCHHHCCEEECCCCCCCCCEEECCCCCHHHHHH
WLYATRLTVAAFSVGRARRCFDMAVDYAAQRKQFGQAIAKFQGVSFQIADMITEIDAADH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCC
LTLAGAWRLDKGLPANREIASAKLYATEMLARVTDTTLQIFGGMGLMDDFPIERFWRDAR
EEEEECEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VERIWDGTSEIQRHIISRDLFRPLGA
HHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]