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The map label for this gene is oxyR [H]

Identifier: 89056187

GI number: 89056187

Start: 3778684

End: 3779622

Strand: Direct

Name: oxyR [H]

Synonym: Jann_3696

Alternate gene names: 89056187

Gene position: 3778684-3779622 (Clockwise)

Preceding gene: 89056179

Following gene: 89056188

Centisome position: 87.51

GC content: 64.64

Gene sequence:

>939_bases
GTGCACAATACGACCCTCCCCTTCACTCTGAGACAGCTCCGCTATCTCGCGGCGCTTGAAGATATGCGCCATTTCCGCGA
GGCGGCAGAGGCGTGTGGCATTTCGCAACCGTCCCTGTCGGTGCAGATCAAATCCCTGGAAGACGCCCTTGGCCTGACCC
TGGTCGAGCGTGGCCGCGGCCCCGTGCGCCTGACCCATGCGGGCCGCGAAGTGTCGCGCCGCGCACGCGAGATCCTGGAC
GCGGGCCAGGGCATTCTGGACCTGTCGGCGACACTGCAATCAGGGTTGGGGGGCACGTTGCGCATGGGCACCTCTACCAC
GTTGGGGCCCTATCTGATGCCCCATGTGGTGGGCGACCTGCATCGCTCTCACCCGGATCTGCGGCTCTATATCCGCGAAA
ACGCCCCCAGGAATCTGGTGCGGGAACTCAATGACGGCACCCACGATCTGATCCTGACGCAATTGCCGGTCCAGGGCGCA
CGCCTGACCTCCACGCGTCTGTTCCGGGAACCTCTGGGCCTCGCGATGCCGGTCGATCATGCGCTGTCAGAGGCCAGCAA
CATCGACGGGCCGGATCTTGAGGGGCAGTCGATCCTGTCGCTGTCGCCTGCCTATGCCCTGCATGATCAGATCAATGCAC
TGTGCGTGGAGACCGGCGCGCAGATGTCCCGGGATTACGAGGGCACGTCGCTGGATGCGCTGCGGCAGATGGTGGCGCTG
GATATGGGGCTGACGTTTCTACCCGCGCTCTACGTCCGGTCCGAGATCGAAGGGCGTGCGCAGGACGTTGTCGTACGACC
GTTCCGGGGGCGAAAATTCTTCCGATCCATCGGGTTGGTCTGGCGGTCATCATCGGGCGCGGCCCCGGCATTCGAGCGGT
TGGCGGGCGCGATCCGCGACACCGCGCGTCGCTTCCCGGAACTGGTTCTGGAAGGTTAA

Upstream 100 bases:

>100_bases
GCGATTAACTTTTTAGCGTCGTGAGCTTGAGATATCGCAGCGGCGGCATAGTTCCAACCCAAGCAAACATGAAATACCCA
TTGGAAAAAGCTATAGACCC

Downstream 100 bases:

>100_bases
CAAAATGGGAGTCCGGCGGGCCTTCGCCGATGCGGCGCCTGCTTAACGTGGTGTGCCCATTGACCTTTAGGGGTCACCCG
GGAAAACTATTCAGATGAAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MHNTTLPFTLRQLRYLAALEDMRHFREAAEACGISQPSLSVQIKSLEDALGLTLVERGRGPVRLTHAGREVSRRAREILD
AGQGILDLSATLQSGLGGTLRMGTSTTLGPYLMPHVVGDLHRSHPDLRLYIRENAPRNLVRELNDGTHDLILTQLPVQGA
RLTSTRLFREPLGLAMPVDHALSEASNIDGPDLEGQSILSLSPAYALHDQINALCVETGAQMSRDYEGTSLDALRQMVAL
DMGLTFLPALYVRSEIEGRAQDVVVRPFRGRKFFRSIGLVWRSSSGAAPAFERLAGAIRDTARRFPELVLEG

Sequences:

>Translated_312_residues
MHNTTLPFTLRQLRYLAALEDMRHFREAAEACGISQPSLSVQIKSLEDALGLTLVERGRGPVRLTHAGREVSRRAREILD
AGQGILDLSATLQSGLGGTLRMGTSTTLGPYLMPHVVGDLHRSHPDLRLYIRENAPRNLVRELNDGTHDLILTQLPVQGA
RLTSTRLFREPLGLAMPVDHALSEASNIDGPDLEGQSILSLSPAYALHDQINALCVETGAQMSRDYEGTSLDALRQMVAL
DMGLTFLPALYVRSEIEGRAQDVVVRPFRGRKFFRSIGLVWRSSSGAAPAFERLAGAIRDTARRFPELVLEG
>Mature_312_residues
MHNTTLPFTLRQLRYLAALEDMRHFREAAEACGISQPSLSVQIKSLEDALGLTLVERGRGPVRLTHAGREVSRRAREILD
AGQGILDLSATLQSGLGGTLRMGTSTTLGPYLMPHVVGDLHRSHPDLRLYIRENAPRNLVRELNDGTHDLILTQLPVQGA
RLTSTRLFREPLGLAMPVDHALSEASNIDGPDLEGQSILSLSPAYALHDQINALCVETGAQMSRDYEGTSLDALRQMVAL
DMGLTFLPALYVRSEIEGRAQDVVVRPFRGRKFFRSIGLVWRSSSGAAPAFERLAGAIRDTARRFPELVLEG

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=37.542662116041, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1788887, Length=276, Percent_Identity=27.8985507246377, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI2367136, Length=267, Percent_Identity=28.4644194756554, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI157672245, Length=242, Percent_Identity=28.099173553719, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787879, Length=285, Percent_Identity=27.3684210526316, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693105, Length=285, Percent_Identity=22.4561403508772, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787530, Length=246, Percent_Identity=22.7642276422764, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787601, Length=144, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788296, Length=241, Percent_Identity=23.2365145228216, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34294; Mature: 34294

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNTTLPFTLRQLRYLAALEDMRHFREAAEACGISQPSLSVQIKSLEDALGLTLVERGRG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCC
PVRLTHAGREVSRRAREILDAGQGILDLSATLQSGLGGTLRMGTSTTLGPYLMPHVVGDL
CEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHH
HRSHPDLRLYIRENAPRNLVRELNDGTHDLILTQLPVQGARLTSTRLFREPLGLAMPVDH
HHCCCCEEEEEECCCCHHHHHHHCCCCHHEEEEECCCCCCHHHHHHHHHHCCCCCCCHHH
ALSEASNIDGPDLEGQSILSLSPAYALHDQINALCVETGAQMSRDYEGTSLDALRQMVAL
HHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DMGLTFLPALYVRSEIEGRAQDVVVRPFRGRKFFRSIGLVWRSSSGAAPAFERLAGAIRD
HHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHH
TARRFPELVLEG
HHHHHHHHHCCC
>Mature Secondary Structure
MHNTTLPFTLRQLRYLAALEDMRHFREAAEACGISQPSLSVQIKSLEDALGLTLVERGRG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCC
PVRLTHAGREVSRRAREILDAGQGILDLSATLQSGLGGTLRMGTSTTLGPYLMPHVVGDL
CEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHH
HRSHPDLRLYIRENAPRNLVRELNDGTHDLILTQLPVQGARLTSTRLFREPLGLAMPVDH
HHCCCCEEEEEECCCCHHHHHHHCCCCHHEEEEECCCCCCHHHHHHHHHHCCCCCCCHHH
ALSEASNIDGPDLEGQSILSLSPAYALHDQINALCVETGAQMSRDYEGTSLDALRQMVAL
HHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DMGLTFLPALYVRSEIEGRAQDVVVRPFRGRKFFRSIGLVWRSSSGAAPAFERLAGAIRD
HHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHH
TARRFPELVLEG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]