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The map label for this gene is 89055886

Identifier: 89055886

GI number: 89055886

Start: 3448045

End: 3449280

Strand: Direct

Name: 89055886

Synonym: Jann_3395

Alternate gene names: NA

Gene position: 3448045-3449280 (Clockwise)

Preceding gene: 89055883

Following gene: 89055893

Centisome position: 79.85

GC content: 64.97

Gene sequence:

>1236_bases
ATGCCGATGCAGTGCAGCCTTAGCGTGGGAGCATACGCGAAAGGGAATCTCATGCGCTTGTTCACCAAACTTCTCGGGCG
CGCACTTTTGCTGGTGCTCGTGGGCCTCGCAGCCTTCCTGACCTTTGGGCCGGGCTATGTGGAGGCGGAGCGCAATGGCG
TGAACTGGCAGGGCCCCTACCCCGTATCCGACGAGGCCGCAGCCCTGCACGACAGCCTTACCATTGGCGACTGGCACGCC
GACAGCCTGCTATGGAACCGCGATCTGACCGAGCGTGGCGCGACGGGCCACGTCGATATTCCGCGTTTGCTGGAGGGCAA
TGTGGCGGTGCAGGTGTTCACGGCCGTGACCAAATCGCCTGCGGGGCAGAATTATCACGAGAATTCGGGCGATGCGCGCG
ATAACATCACGCTGTTGGCCGTGGGACAGCTTTGGCCGCCCCGGACCTGGACCAGCCTGGTCGAGCGCGCGCTCTATCAG
GCCGAGCGGTTGCACGGCTTTGCCGAGGCGTCCGACGGGCTGCGGGTGATCACCTCAGCCACCGAATTGGAGGCTCTGCT
GGAGGCCCGCAGTCAGGGTTTGCAGACCGTCGGCGGGATGCTGGGCATTGAAGGGGCCCATGCGCTGGAAGGGGATATCG
GAAACCTCGACCGGCTTGAAGGGGCGGGATATCGGCTGATCGGATTGCACCACTTCTTCGACAATGAACTCGGCGGCTCG
CTCCACGGTGTGGGCAACCAGGGCCTGACGGAGTTTGGCTACACGGTCGTGGCGGGAATCGTGGCGCGCGGCATGGTCCT
CGACCTCGCCCATTCCTCCCCGCAGGTGGCCCGTGATGTGATCGCTGCCACGGACATCCCGTTGATCGTCAGCCATACCG
GCCTGCGCTCCGCCTGTGACGCGCACCGCAACTTCCCCGATGACCTGATGCGAGACATCGTGGCCAACGGCGCAGACCAG
GGTGGCGGCGTGATCGGGATCGGCTATTGGGCCGATGTCACCTGTGATGACAGTCCGGACGGGGTGGCGCGGGTGATCAT
GGCGGCGATCGAAGCGCTTGGGGTCGATCACGTCTCCCTTGGGTCGGACTATGACGGATCGGTCACGGTTGGCTTTGATA
CCTCGGAACTATCGGCCCTGACCGATGCGCTCCTGCGGGCCGGGGCGCGGGAGGATCAGATCCGCGCCGTGATGGGGGGC
AACATGCTGCGGGTCCTGCGGGCGCGGCTGGACTAG

Upstream 100 bases:

>100_bases
ATGCGGCGCACCATGGCAGTCCCTTCCGTTAATCTTGGGAAAAGTTAGCTTCGCGCGGACACCCGGCAAGAGACCCGCCG
CCGCGCGAGGTCACGCTTGC

Downstream 100 bases:

>100_bases
AGGCCAGTGCGGCGGGCGCGGATTGACCGCCCCCACCTCGCGCACCCCCTTGAAACCGAGGGGTTGCAAGGTTGCAACCA
GGAATTAAGTCTTTGCAAAG

Product: peptidase M19, renal dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MPMQCSLSVGAYAKGNLMRLFTKLLGRALLLVLVGLAAFLTFGPGYVEAERNGVNWQGPYPVSDEAAALHDSLTIGDWHA
DSLLWNRDLTERGATGHVDIPRLLEGNVAVQVFTAVTKSPAGQNYHENSGDARDNITLLAVGQLWPPRTWTSLVERALYQ
AERLHGFAEASDGLRVITSATELEALLEARSQGLQTVGGMLGIEGAHALEGDIGNLDRLEGAGYRLIGLHHFFDNELGGS
LHGVGNQGLTEFGYTVVAGIVARGMVLDLAHSSPQVARDVIAATDIPLIVSHTGLRSACDAHRNFPDDLMRDIVANGADQ
GGGVIGIGYWADVTCDDSPDGVARVIMAAIEALGVDHVSLGSDYDGSVTVGFDTSELSALTDALLRAGAREDQIRAVMGG
NMLRVLRARLD

Sequences:

>Translated_411_residues
MPMQCSLSVGAYAKGNLMRLFTKLLGRALLLVLVGLAAFLTFGPGYVEAERNGVNWQGPYPVSDEAAALHDSLTIGDWHA
DSLLWNRDLTERGATGHVDIPRLLEGNVAVQVFTAVTKSPAGQNYHENSGDARDNITLLAVGQLWPPRTWTSLVERALYQ
AERLHGFAEASDGLRVITSATELEALLEARSQGLQTVGGMLGIEGAHALEGDIGNLDRLEGAGYRLIGLHHFFDNELGGS
LHGVGNQGLTEFGYTVVAGIVARGMVLDLAHSSPQVARDVIAATDIPLIVSHTGLRSACDAHRNFPDDLMRDIVANGADQ
GGGVIGIGYWADVTCDDSPDGVARVIMAAIEALGVDHVSLGSDYDGSVTVGFDTSELSALTDALLRAGAREDQIRAVMGG
NMLRVLRARLD
>Mature_410_residues
PMQCSLSVGAYAKGNLMRLFTKLLGRALLLVLVGLAAFLTFGPGYVEAERNGVNWQGPYPVSDEAAALHDSLTIGDWHAD
SLLWNRDLTERGATGHVDIPRLLEGNVAVQVFTAVTKSPAGQNYHENSGDARDNITLLAVGQLWPPRTWTSLVERALYQA
ERLHGFAEASDGLRVITSATELEALLEARSQGLQTVGGMLGIEGAHALEGDIGNLDRLEGAGYRLIGLHHFFDNELGGSL
HGVGNQGLTEFGYTVVAGIVARGMVLDLAHSSPQVARDVIAATDIPLIVSHTGLRSACDAHRNFPDDLMRDIVANGADQG
GGVIGIGYWADVTCDDSPDGVARVIMAAIEALGVDHVSLGSDYDGSVTVGFDTSELSALTDALLRAGAREDQIRAVMGGN
MLRVLRARLD

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI11641269, Length=248, Percent_Identity=32.6612903225806, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI193211608, Length=278, Percent_Identity=28.0575539568345, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI193211610, Length=278, Percent_Identity=28.0575539568345, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI189458885, Length=352, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI4758190, Length=352, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI161083233, Length=328, Percent_Identity=28.9634146341463, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI221475880, Length=352, Percent_Identity=26.7045454545455, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281362638, Length=334, Percent_Identity=27.5449101796407, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281362636, Length=334, Percent_Identity=27.5449101796407, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 43656; Mature: 43525

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMQCSLSVGAYAKGNLMRLFTKLLGRALLLVLVGLAAFLTFGPGYVEAERNGVNWQGPY
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCC
PVSDEAAALHDSLTIGDWHADSLLWNRDLTERGATGHVDIPRLLEGNVAVQVFTAVTKSP
CCCCCHHHHHCCCEECCCCCCHHEECCCHHHCCCCCCCCCHHHHCCCCEEEEEEHHHCCC
AGQNYHENSGDARDNITLLAVGQLWPPRTWTSLVERALYQAERLHGFAEASDGLRVITSA
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHH
TELEALLEARSQGLQTVGGMLGIEGAHALEGDIGNLDRLEGAGYRLIGLHHFFDNELGGS
HHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHCCCCEEEEEEHHHHCCCCCCC
LHGVGNQGLTEFGYTVVAGIVARGMVLDLAHSSPQVARDVIAATDIPLIVSHTGLRSACD
CCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCEEEECCCHHHHHH
AHRNFPDDLMRDIVANGADQGGGVIGIGYWADVTCDDSPDGVARVIMAAIEALGVDHVSL
HHCCCHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEC
GSDYDGSVTVGFDTSELSALTDALLRAGAREDQIRAVMGGNMLRVLRARLD
CCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
PMQCSLSVGAYAKGNLMRLFTKLLGRALLLVLVGLAAFLTFGPGYVEAERNGVNWQGPY
CCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCC
PVSDEAAALHDSLTIGDWHADSLLWNRDLTERGATGHVDIPRLLEGNVAVQVFTAVTKSP
CCCCCHHHHHCCCEECCCCCCHHEECCCHHHCCCCCCCCCHHHHCCCCEEEEEEHHHCCC
AGQNYHENSGDARDNITLLAVGQLWPPRTWTSLVERALYQAERLHGFAEASDGLRVITSA
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHH
TELEALLEARSQGLQTVGGMLGIEGAHALEGDIGNLDRLEGAGYRLIGLHHFFDNELGGS
HHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHCCCCEEEEEEHHHHCCCCCCC
LHGVGNQGLTEFGYTVVAGIVARGMVLDLAHSSPQVARDVIAATDIPLIVSHTGLRSACD
CCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCEEEECCCHHHHHH
AHRNFPDDLMRDIVANGADQGGGVIGIGYWADVTCDDSPDGVARVIMAAIEALGVDHVSL
HHCCCHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEC
GSDYDGSVTVGFDTSELSALTDALLRAGAREDQIRAVMGGNMLRVLRARLD
CCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]