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The map label for this gene is pgm [H]

Identifier: 89055608

GI number: 89055608

Start: 3154479

End: 3156110

Strand: Direct

Name: pgm [H]

Synonym: Jann_3117

Alternate gene names: 89055608

Gene position: 3154479-3156110 (Clockwise)

Preceding gene: 89055607

Following gene: 89055609

Centisome position: 73.05

GC content: 64.95

Gene sequence:

>1632_bases
ATGCAGCCTGATACCGTTGCCACGCAGCCCATCGCGGGCCAGAAGCCCGGCACATCCGGCCTTCGCAAGAAAACCCGCAC
CTTCATGGAGCCGCACTTTCTGGAAAACTACGTTCAGTCGATCATCGACGGGATCGGCGGTGTGGTCGGGCAGACCTTGG
TGGTGGGCGGCGACGGGCGCTACTTCAACGACCGCGCCATTCAGGTGATCCTGCGGATGCTGGCGGCCAACGGCGCTGCG
GGCGCGGTGGTGGGCCAGGGCGGTATCCTATCAACGCCTGCCGCCTCTCACCTCATCCGCAAGCGGGGCACGGGCGGCGG
CTTCATCCTGTCGGCCAGCCACAACCCCGGCGGGATCGACGCGGATTTCGGGTTGAAATTCAATGGTCCCAATGGCGGGC
CTGCATCAGAGGGTGTGACCGCGAAGATCTTTGCCGCGACCGAAGCGATCACCGAATACCGCATCGTGGAAGCGCAGGAT
GTGGATCTGGATACCATCGGGACCAGCACCCTCGGCGATCTGTCCGTGGAAATCGTCAACCCGGTCGCCGATTACGCAGA
GCTGATGGAGAGCCTGTTCGATTTCGGCAAGATCCGCGCGCTCTTTGCCTCCGGCTTCCGGATGCGGTTCGATGCGATGC
ACGCGGTCACGGGTCCCTATGCCACGGCGATCCTCGAAGACACGCTTGGGGCCGCGACGGGCACGGTGATCAACGGCACC
CCCTCCCCCGATTTCGGCCAGGGCCACCCGGACCCCAACCCTGTCTGGGCAAAGACCCTGATGGATGAGATGTACGGCGA
CGATTCCCCGGACTTTGGGGCCGCGTCTGATGGCGATGGTGATCGCAACATGATCGTGGGTCGCCGCCAATATGTGACGC
CCTCCGACAGCCTTGCGCTTCTGGCGGCCCACGCCCATCGTGCGCCTGCCTATGCCAACGGTCTTGCCGGTGTCGCGCGC
TCCATGCCGACCTCGGGGGCCGTTGATCGCGTGGCCGAGGCGCAAGGCATTGACTGTTATGAGACCCCCACCGGCTGGAA
GTTCTTCGGGACCCTTCTGGACGCAGGAAAGGTAACGCTGTGCGGCGAGGAAAGTGCCGGCACCGGATCAGACCATGTAC
GCGAAAAAGACGGGCTTTGGGCTGTGCTTCTTTGGCTCAACATCCTGGCGGACAGTGGCCAGTCCGTGGCTGATCTGATG
GCCGCGCTCTGGCGGGACTTTGGGCGCTGTTATTACAGCCGCCACGACTATGAGGATGTGGAGGTCGACAAAGCCAATGC
GGTCATGGACGGGTTGCGTGCGCGCCTTGCCACACTGCCGGGCACACAGGTCGCGGGCCTCACCGTCACCTTCGCCGATG
AATTCGCCTATGACGATCCCGTGGACGGCAGCCGCGCGGAGGCTCAGGGCCTGCGCATCGGGTTCGAGGGCGGCGCGCGC
GCCGTCTTCCGCCTCTCGGGCACCGGCACGGTTGGGGCCACGATCCGGATGTATCTGGAACGGCTGGAGACGTCCGCCGA
CGCGCTGGATCAACCCGCCGAGACCGCTTTGCGCCCCGTTGTCGACGCCGCGCTGACGCTCTCGGATCTGGCGGCGCTGA
CCGGGCGCGACAGCCCCAACGTCATCACGTAA

Upstream 100 bases:

>100_bases
CAACCCGACCCAACCGCCCTGCCCCCCGGCGCAGACCCGCAGATCGACGCCAATTGCGTCGTCGTCTATGAGCTCCAACC
CAACACGGAAGGACATAATC

Downstream 100 bases:

>100_bases
AGGCACCTGTTCCTCCGCCCCGAAACATGGCAAGGCATCCGGGACACTTTTGATCCGCGGAATACCAAAATGAACGCCAT
GTCAGACCTTTCCTCCGACG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MQPDTVATQPIAGQKPGTSGLRKKTRTFMEPHFLENYVQSIIDGIGGVVGQTLVVGGDGRYFNDRAIQVILRMLAANGAA
GAVVGQGGILSTPAASHLIRKRGTGGGFILSASHNPGGIDADFGLKFNGPNGGPASEGVTAKIFAATEAITEYRIVEAQD
VDLDTIGTSTLGDLSVEIVNPVADYAELMESLFDFGKIRALFASGFRMRFDAMHAVTGPYATAILEDTLGAATGTVINGT
PSPDFGQGHPDPNPVWAKTLMDEMYGDDSPDFGAASDGDGDRNMIVGRRQYVTPSDSLALLAAHAHRAPAYANGLAGVAR
SMPTSGAVDRVAEAQGIDCYETPTGWKFFGTLLDAGKVTLCGEESAGTGSDHVREKDGLWAVLLWLNILADSGQSVADLM
AALWRDFGRCYYSRHDYEDVEVDKANAVMDGLRARLATLPGTQVAGLTVTFADEFAYDDPVDGSRAEAQGLRIGFEGGAR
AVFRLSGTGTVGATIRMYLERLETSADALDQPAETALRPVVDAALTLSDLAALTGRDSPNVIT

Sequences:

>Translated_543_residues
MQPDTVATQPIAGQKPGTSGLRKKTRTFMEPHFLENYVQSIIDGIGGVVGQTLVVGGDGRYFNDRAIQVILRMLAANGAA
GAVVGQGGILSTPAASHLIRKRGTGGGFILSASHNPGGIDADFGLKFNGPNGGPASEGVTAKIFAATEAITEYRIVEAQD
VDLDTIGTSTLGDLSVEIVNPVADYAELMESLFDFGKIRALFASGFRMRFDAMHAVTGPYATAILEDTLGAATGTVINGT
PSPDFGQGHPDPNPVWAKTLMDEMYGDDSPDFGAASDGDGDRNMIVGRRQYVTPSDSLALLAAHAHRAPAYANGLAGVAR
SMPTSGAVDRVAEAQGIDCYETPTGWKFFGTLLDAGKVTLCGEESAGTGSDHVREKDGLWAVLLWLNILADSGQSVADLM
AALWRDFGRCYYSRHDYEDVEVDKANAVMDGLRARLATLPGTQVAGLTVTFADEFAYDDPVDGSRAEAQGLRIGFEGGAR
AVFRLSGTGTVGATIRMYLERLETSADALDQPAETALRPVVDAALTLSDLAALTGRDSPNVIT
>Mature_543_residues
MQPDTVATQPIAGQKPGTSGLRKKTRTFMEPHFLENYVQSIIDGIGGVVGQTLVVGGDGRYFNDRAIQVILRMLAANGAA
GAVVGQGGILSTPAASHLIRKRGTGGGFILSASHNPGGIDADFGLKFNGPNGGPASEGVTAKIFAATEAITEYRIVEAQD
VDLDTIGTSTLGDLSVEIVNPVADYAELMESLFDFGKIRALFASGFRMRFDAMHAVTGPYATAILEDTLGAATGTVINGT
PSPDFGQGHPDPNPVWAKTLMDEMYGDDSPDFGAASDGDGDRNMIVGRRQYVTPSDSLALLAAHAHRAPAYANGLAGVAR
SMPTSGAVDRVAEAQGIDCYETPTGWKFFGTLLDAGKVTLCGEESAGTGSDHVREKDGLWAVLLWLNILADSGQSVADLM
AALWRDFGRCYYSRHDYEDVEVDKANAVMDGLRARLATLPGTQVAGLTVTFADEFAYDDPVDGSRAEAQGLRIGFEGGAR
AVFRLSGTGTVGATIRMYLERLETSADALDQPAETALRPVVDAALTLSDLAALTGRDSPNVIT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=558, Percent_Identity=50.8960573476703, Blast_Score=534, Evalue=1e-152,
Organism=Homo sapiens, GI21361621, Length=558, Percent_Identity=49.8207885304659, Blast_Score=526, Evalue=1e-149,
Organism=Homo sapiens, GI133922562, Length=559, Percent_Identity=45.2593917710197, Blast_Score=456, Evalue=1e-128,
Organism=Homo sapiens, GI290463104, Length=366, Percent_Identity=50, Blast_Score=358, Evalue=1e-98,
Organism=Homo sapiens, GI239743670, Length=128, Percent_Identity=42.96875, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI239741729, Length=128, Percent_Identity=44.53125, Blast_Score=94, Evalue=5e-19,
Organism=Escherichia coli, GI1786904, Length=424, Percent_Identity=29.0094339622642, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17535441, Length=560, Percent_Identity=48.9285714285714, Blast_Score=513, Evalue=1e-145,
Organism=Saccharomyces cerevisiae, GI6323752, Length=571, Percent_Identity=45.3590192644483, Blast_Score=492, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6322722, Length=570, Percent_Identity=45.2631578947368, Blast_Score=486, Evalue=1e-138,
Organism=Drosophila melanogaster, GI17864244, Length=562, Percent_Identity=46.9750889679715, Blast_Score=515, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 57090; Mature: 57090

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPDTVATQPIAGQKPGTSGLRKKTRTFMEPHFLENYVQSIIDGIGGVVGQTLVVGGDGR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCC
YFNDRAIQVILRMLAANGAAGAVVGQGGILSTPAASHLIRKRGTGGGFILSASHNPGGID
EECHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCC
ADFGLKFNGPNGGPASEGVTAKIFAATEAITEYRIVEAQDVDLDTIGTSTLGDLSVEIVN
CCCCEEECCCCCCCCCCCCEEEEEHHHHHHHHEEEEECCCCCCHHCCCCCCCCEEHHHHH
PVADYAELMESLFDFGKIRALFASGFRMRFDAMHAVTGPYATAILEDTLGAATGTVINGT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEECCC
PSPDFGQGHPDPNPVWAKTLMDEMYGDDSPDFGAASDGDGDRNMIVGRRQYVTPSDSLAL
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCEECCCCCCHHH
LAAHAHRAPAYANGLAGVARSMPTSGAVDRVAEAQGIDCYETPTGWKFFGTLLDAGKVTL
HHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEECCCCHHHHHHHHCCCCEEE
CGEESAGTGSDHVREKDGLWAVLLWLNILADSGQSVADLMAALWRDFGRCYYSRHDYEDV
ECCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
EVDKANAVMDGLRARLATLPGTQVAGLTVTFADEFAYDDPVDGSRAEAQGLRIGFEGGAR
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHCCEEEEECCCCE
AVFRLSGTGTVGATIRMYLERLETSADALDQPAETALRPVVDAALTLSDLAALTGRDSPN
EEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VIT
CCC
>Mature Secondary Structure
MQPDTVATQPIAGQKPGTSGLRKKTRTFMEPHFLENYVQSIIDGIGGVVGQTLVVGGDGR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCC
YFNDRAIQVILRMLAANGAAGAVVGQGGILSTPAASHLIRKRGTGGGFILSASHNPGGID
EECHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCC
ADFGLKFNGPNGGPASEGVTAKIFAATEAITEYRIVEAQDVDLDTIGTSTLGDLSVEIVN
CCCCEEECCCCCCCCCCCCEEEEEHHHHHHHHEEEEECCCCCCHHCCCCCCCCEEHHHHH
PVADYAELMESLFDFGKIRALFASGFRMRFDAMHAVTGPYATAILEDTLGAATGTVINGT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEECCC
PSPDFGQGHPDPNPVWAKTLMDEMYGDDSPDFGAASDGDGDRNMIVGRRQYVTPSDSLAL
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCEECCCCCCHHH
LAAHAHRAPAYANGLAGVARSMPTSGAVDRVAEAQGIDCYETPTGWKFFGTLLDAGKVTL
HHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEECCCCHHHHHHHHCCCCEEE
CGEESAGTGSDHVREKDGLWAVLLWLNILADSGQSVADLMAALWRDFGRCYYSRHDYEDV
ECCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
EVDKANAVMDGLRARLATLPGTQVAGLTVTFADEFAYDDPVDGSRAEAQGLRIGFEGGAR
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHCCEEEEECCCCE
AVFRLSGTGTVGATIRMYLERLETSADALDQPAETALRPVVDAALTLSDLAALTGRDSPN
EEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VIT
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]