| Definition | Jannaschia sp. CCS1 chromosome, complete genome. |
|---|---|
| Accession | NC_007802 |
| Length | 4,317,977 |
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The map label for this gene is polS [H]
Identifier: 89055397
GI number: 89055397
Start: 2926037
End: 2926804
Strand: Direct
Name: polS [H]
Synonym: Jann_2906
Alternate gene names: 89055397
Gene position: 2926037-2926804 (Clockwise)
Preceding gene: 89055396
Following gene: 89055398
Centisome position: 67.76
GC content: 62.89
Gene sequence:
>768_bases ATGACGCGGCTGACGGGAAAAGGCGCGTTGATCACCGGTGCCGCGCGCGGCATCGGGCGTGCCTTTGCTGAACGCTACAT CGCGGAAGGCGCGCGGGTGGCGATTGCCGATATCGACCTGACCCGTGCCGAGGCAACGGCGGCAGAGATCGGGGCCATTG CGGTCCAGATGGATGTCTCTTGCGAGGATTCCATAGCCGACGGGGTCACTGCGGCTGCAGACGCGTTGGGGCAGATCGAC ATCCTGATCAACAACGCCGCCGTCTTCACTGCCGCCCCGCTGACAGAGATCACCTACAAGGACTATGCGGACGTCTTCGA CATCAACGTGGGCGGGACGCTGTTCACCATGCAGGCGGTGGCGAAACACATGATTGACCGCGGCATCCGCGGCAAGATCA TCAACATGGCCTCCCAGGCCGGCCGGAGGGGAGAGCCGTTGGTCGCCGTCTATTGCGCCACGAAAGCCGCCGTCATCAGC CTGACCCAATCGGCCGGTCTCAACCTGATCGAGCACGGCATCAACGTGAATGCCATCGCACCGGGCGTGGTGGATGGGGA GCATTGGGATGGTGTCGACGCGTTCTTTGCCAGACACGAAGGCAAGGCGCCCGGCCAGAAGAAACGCGAAGTCGGCGAAG CTGTGCCTTACGGACGCATGGGCGTGGCCGAAGACCTGACCGGCATGGCCGTCTTTCTGGCCAGCGACGAGGCGGAATAT ATCGTGTCGCAGACCTACAATGTGGACGGCGGACAATGGATGAGCTGA
Upstream 100 bases:
>100_bases GCGTGAACGGTGCCTTCCTGGTGCGCAGCGGCGATGAGGTCTATCTGACACCGGACCTCGAAAAGCTACACCGGTTCGAC GCAGACGGCCTGCGGATTGC
Downstream 100 bases:
>100_bases CGGGAACGTGCTGATGGGGACTGACATGAAAGATACGACCCCCGCCCTGCCCCTGCGGCTTGATACGCTGGAGGCCCTGC CCCATGGGATTGAGCGGCCG
Product: sorbitol dehydrogenase
Products: NA
Alternate protein names: L-iditol 2-dehydrogenase; Polyol dehydrogenase [H]
Number of amino acids: Translated: 255; Mature: 254
Protein sequence:
>255_residues MTRLTGKGALITGAARGIGRAFAERYIAEGARVAIADIDLTRAEATAAEIGAIAVQMDVSCEDSIADGVTAAADALGQID ILINNAAVFTAAPLTEITYKDYADVFDINVGGTLFTMQAVAKHMIDRGIRGKIINMASQAGRRGEPLVAVYCATKAAVIS LTQSAGLNLIEHGINVNAIAPGVVDGEHWDGVDAFFARHEGKAPGQKKREVGEAVPYGRMGVAEDLTGMAVFLASDEAEY IVSQTYNVDGGQWMS
Sequences:
>Translated_255_residues MTRLTGKGALITGAARGIGRAFAERYIAEGARVAIADIDLTRAEATAAEIGAIAVQMDVSCEDSIADGVTAAADALGQID ILINNAAVFTAAPLTEITYKDYADVFDINVGGTLFTMQAVAKHMIDRGIRGKIINMASQAGRRGEPLVAVYCATKAAVIS LTQSAGLNLIEHGINVNAIAPGVVDGEHWDGVDAFFARHEGKAPGQKKREVGEAVPYGRMGVAEDLTGMAVFLASDEAEY IVSQTYNVDGGQWMS >Mature_254_residues TRLTGKGALITGAARGIGRAFAERYIAEGARVAIADIDLTRAEATAAEIGAIAVQMDVSCEDSIADGVTAAADALGQIDI LINNAAVFTAAPLTEITYKDYADVFDINVGGTLFTMQAVAKHMIDRGIRGKIINMASQAGRRGEPLVAVYCATKAAVISL TQSAGLNLIEHGINVNAIAPGVVDGEHWDGVDAFFARHEGKAPGQKKREVGEAVPYGRMGVAEDLTGMAVFLASDEAEYI VSQTYNVDGGQWMS
Specific function: Catalyzes the oxidation of D-glucitol (sorbitol) to D- fructose, galactitol to D-tagatose and of L-iditol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=31.3492063492063, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=31.9548872180451, Blast_Score=113, Evalue=1e-25, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=29.6153846153846, Blast_Score=111, Evalue=7e-25, Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=35.2040816326531, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=29.4573643410853, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=31.140350877193, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=26.8292682926829, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=30.5882352941176, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=29.5019157088123, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=33.9080459770115, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI4758504, Length=188, Percent_Identity=31.9148936170213, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI4503301, Length=229, Percent_Identity=26.2008733624454, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI83715985, Length=179, Percent_Identity=30.1675977653631, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI210032110, Length=188, Percent_Identity=27.6595744680851, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI109715829, Length=199, Percent_Identity=31.1557788944724, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI126723750, Length=263, Percent_Identity=27.7566539923954, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI40807363, Length=197, Percent_Identity=29.4416243654822, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI223718074, Length=186, Percent_Identity=31.1827956989247, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=28.4210526315789, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI142976729, Length=192, Percent_Identity=26.5625, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=26.3565891472868, Blast_Score=68, Evalue=7e-12, Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=33.4630350194552, Blast_Score=126, Evalue=1e-30, Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=32.8185328185328, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=34.0996168582375, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=32.6693227091633, Blast_Score=114, Evalue=9e-27, Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=28.740157480315, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=30.1204819277108, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=31.1538461538462, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=30.4347826086957, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=29.3436293436293, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=29.5275590551181, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=31.8897637795276, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=27.6679841897233, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1787820, Length=197, Percent_Identity=29.9492385786802, Blast_Score=72, Evalue=4e-14, Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=32.156862745098, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=29.6875, Blast_Score=112, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=29.8507462686567, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=29.5620437956204, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=29.4545454545455, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17562990, Length=274, Percent_Identity=32.1167883211679, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI72000259, Length=275, Percent_Identity=29.8181818181818, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17560220, Length=278, Percent_Identity=29.136690647482, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17560150, Length=273, Percent_Identity=29.6703296703297, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=30.4832713754647, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562908, Length=274, Percent_Identity=28.4671532846715, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=29.4117647058824, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17561402, Length=269, Percent_Identity=29.368029739777, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=29.8507462686567, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=29.0441176470588, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=29.9625468164794, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538486, Length=276, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=27.34375, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=31.9230769230769, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562910, Length=281, Percent_Identity=26.3345195729537, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562904, Length=278, Percent_Identity=26.978417266187, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI71994604, Length=259, Percent_Identity=25.4826254826255, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=29.2134831460674, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=25.390625, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=27.5193798449612, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=29.3040293040293, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=25.7692307692308, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=26.7716535433071, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=28.7179487179487, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=28.1407035175879, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=25.1256281407035, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=25.7731958762887, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17568967, Length=191, Percent_Identity=30.3664921465969, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17567345, Length=175, Percent_Identity=30.8571428571429, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=27.6679841897233, Blast_Score=70, Evalue=7e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=254, Percent_Identity=29.5275590551181, Blast_Score=83, Evalue=5e-17, Organism=Saccharomyces cerevisiae, GI6322861, Length=184, Percent_Identity=30.9782608695652, Blast_Score=81, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6324126, Length=260, Percent_Identity=26.5384615384615, Blast_Score=81, Evalue=2e-16, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=34.7826086956522, Blast_Score=125, Evalue=4e-29, Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=28.4046692607004, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=27.4900398406374, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI21357041, Length=261, Percent_Identity=28.735632183908, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI17737361, Length=190, Percent_Identity=33.1578947368421, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI281364892, Length=170, Percent_Identity=35.8823529411765, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24648944, Length=225, Percent_Identity=30.2222222222222, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI28571526, Length=261, Percent_Identity=27.9693486590038, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=27.4509803921569, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24643142, Length=189, Percent_Identity=31.7460317460317, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI24644337, Length=265, Percent_Identity=29.0566037735849, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24581726, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=28.125, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24640492, Length=191, Percent_Identity=26.7015706806283, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24641232, Length=202, Percent_Identity=27.2277227722772, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI281364494, Length=204, Percent_Identity=29.9019607843137, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24665243, Length=165, Percent_Identity=30.3030303030303, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI221331218, Length=165, Percent_Identity=30.3030303030303, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24580925, Length=196, Percent_Identity=25.5102040816327, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI116007236, Length=202, Percent_Identity=28.2178217821782, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.14 [H]
Molecular weight: Translated: 26721; Mature: 26589
Theoretical pI: Translated: 4.56; Mature: 4.56
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTRLTGKGALITGAARGIGRAFAERYIAEGARVAIADIDLTRAEATAAEIGAIAVQMDVS CCEECCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCEEEEEEECC CEDSIADGVTAAADALGQIDILINNAAVFTAAPLTEITYKDYADVFDINVGGTLFTMQAV CCCHHHCCHHHHHHHHCEEEEEEECCEEEEECCCHHHHHHCCCCEEEECCCCHHHHHHHH AKHMIDRGIRGKIINMASQAGRRGEPLVAVYCATKAAVISLTQSAGLNLIEHGINVNAIA HHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEECCCEEEEEEHHHCCCHHHHCCCCCEEEC PGVVDGEHWDGVDAFFARHEGKAPGQKKREVGEAVPYGRMGVAEDLTGMAVFLASDEAEY CCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHCCCCEEEEEECCCCCE IVSQTYNVDGGQWMS EEEEEEECCCCCCCC >Mature Secondary Structure TRLTGKGALITGAARGIGRAFAERYIAEGARVAIADIDLTRAEATAAEIGAIAVQMDVS CEECCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCEEEEEEECC CEDSIADGVTAAADALGQIDILINNAAVFTAAPLTEITYKDYADVFDINVGGTLFTMQAV CCCHHHCCHHHHHHHHCEEEEEEECCEEEEECCCHHHHHHCCCCEEEECCCCHHHHHHHH AKHMIDRGIRGKIINMASQAGRRGEPLVAVYCATKAAVISLTQSAGLNLIEHGINVNAIA HHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEECCCEEEEEEHHHCCCHHHHCCCCCEEEC PGVVDGEHWDGVDAFFARHEGKAPGQKKREVGEAVPYGRMGVAEDLTGMAVFLASDEAEY CCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHCCCCEEEEEECCCCCE IVSQTYNVDGGQWMS EEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7551049 [H]