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The map label for this gene is cheA [H]

Identifier: 89055332

GI number: 89055332

Start: 2857484

End: 2859730

Strand: Reverse

Name: cheA [H]

Synonym: Jann_2841

Alternate gene names: 89055332

Gene position: 2859730-2857484 (Counterclockwise)

Preceding gene: 89055333

Following gene: 89055331

Centisome position: 66.23

GC content: 60.17

Gene sequence:

>2247_bases
ATGACGGTCGGCGGATCAGACGAGTTTCGCGCCTCCTTTTTCGAGGAATGCGAAGAGCTGCTGGAAGCCATGCATGATGG
CTTCGGCCTCATGGTGAATGGCGAGGATGATGACGAGACCATCCACGTTGTCTTTCGGGCCGTCCATTCGATCAAGGGCG
GGTCGGGGGCGTTCGGTCTCGATGATCTGGTGGCCTTTGCACACCATTTTGAAACGGCTCTCGACCGGGTCCGCGCGGGG
AAAACCGAGTCATCAGACGATCTTCTGTCCCTGTTTCAGCTATGTGGCGATCACCTGTCTGATCTGGTCGCGGCGGCCCG
CAACGGAGATGCGGTCGAGCCTGCGCAGGCCGAGGCGCTCAGCCGCCAACTGGATGAGGTGATTGGCAGCCCGGAGGACA
CCGATATATCGGAGACGGACGCCGCCGAGACGTTCGAGCCCCTGACATTCGATTTCGATGCCTTTGATGACCCGTCGTCA
TTGCCCGGGATCGCCGATGATGGGGCAGAGGACATGCGGGCCGGGTTCAACGTGACATTCGTCGCTGAACCGGAACTGTT
CTCTTGTGGCAATGAGCCGGCGTTGCTGTTCAAGGCGCTGGACAGATACGGGCGCGTCCAGGTCGCCGCAGACCTTGACG
ACGTGCCGAGCCTCAGCCGCCTTGATCCGACCATGCCTTACATGAAGTGGTCAATTGATCTTGAAACAGACGCCACCGAG
GATGTGATCCGCGACGTTTTTGACTTCGTATCCGATTGCGCCGTGATCGACATTGCGCCGCTTGACCGATCCGGGCCTCC
CTTGTCCGAACTACCGGACCCGATCGCGGACGACGGACCCGGTGCGGTCGAGCCGACGCTGCCCCAAATCGCCCCGGTTC
CGCCGGTTCAGGAGGCGATTGTTGCCAAGGTTGAAGACACATCGGCCCCGCCAACGCCGCCCGAATCGTCCCCCCCGCAG
GAGGTCGGAGCGTCCAAACCAACCGCACCCGATGCTGCGAAGACCACTGCGGCACCCCAGACGATCCGGGTGGATTTCGA
ACGGGTCGACAAGCTGATCAATCTCGTTGGTGAGTTGGTGATCAAGGAAGCGATGCTGTCCCAGGCGGTCGAAAAACTAA
ACCTGACCAACGGCAACGATGTTCTGCAGGAAATAGAGGGCCTTAAACAGCTGGCTGGCGAGATTCAGGAAGGCGTCATG
GCCATTCGGGCGCAACCCGTCAAACCCCTGTTTCAACGGATGGCTCGGACGATTCGAGATGCAAGCACGACCACGGGAAA
ACGCGTCCGGCTGACCATGAAAGGGGAGGCAGCCGAGGTCGACAAGACCGTGCTGGAGCGCCTCGTTGATCCGCTCAACC
ACATGGTTCGCAATGCGGTCGACCATGGTCTCGAATCAGCTGAGGAGCGCATAGCCGCGGGCAAACCGGCGGAAGGGACG
GTGACCCTTTCGGCGGCCCATCGTTCCGGCCGCGTTGTGATCGAGATCTCCGATGACGGGGGCGGGATCAACCGGGACAA
GGTCCGTCAACACGCAGAGTCCAGGGGCCTCGTCTTACCCGATGCCACGCTGACGCCGTCCGAGGTGGACGCCTTGCTGT
TCATGCCCGGCTTCTCGATGAAAGAGGAAGTGTCCGAATTGTCCGGGCGCGGCGTGGGACTTGACGTCGTGCGCAGCGAG
ATTTCCGCCTTGGGTGGGCGCATGTCGATCTCCTCGGAACTGGGCAAAGGCACAGATTTTTCGATCAGTTTACCCCTGAC
CCTGGCCGTTCTGGAGGGGATGGTTGTTGAGGTTGCGGGTCAAACCATGGTCGTGCCGATCACGGCCATTCAGGAGACGC
TGCAACCCAGTACCGCCCAGATCCATACCATAGGGTCTGGCGGCCGCGTTCTGTCCATTCGCAACACATTGGTGCCAATC
GAAGATCTGGGCGCCATTTTCGGGTTTCGGGATACCCCAATGGATCTCGACGACCGTGTCCTGCTCGTCATCGAGACCGA
AACTGAAAAACGCTGCGCCTTGATTGTGGATCGTCTGCAGGACCAGCGCCAAGTCGTCATCAAGAGCTTGGAAACCAACT
ATTCCCACGTTTCAGGCATTGCTGCCGCCACGATCCTTGGCGATGGCCGTATCGCGCTGATCGTTGACCCGGAGGATATC
GCCGGAGGCATTGCGCTACCCCAATCCTGCCAGACCTCTGCCCCCGACCTGATCGCTTCAGAAGGAGACCAACATGTCGC
AAGTTGA

Upstream 100 bases:

>100_bases
GCGCCCGAAAGGCCGGCGCGACCGGTTGGATCGTGAAGCCGTTCGACGATGAAAAGCTCGTCTGGGCGATCGAGCGTGTG
GCCAATACCGGAGGCGCGGC

Downstream 100 bases:

>100_bases
AACTGACCAGCACGCCAAGCACCACGAGGTCGTCGCGTTTCGCGTGGCCGAGCAAGATTTTTGTTTCGACATCATGTCCG
TGCGCGAGATCAGAGGATGG

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 748; Mature: 747

Protein sequence:

>748_residues
MTVGGSDEFRASFFEECEELLEAMHDGFGLMVNGEDDDETIHVVFRAVHSIKGGSGAFGLDDLVAFAHHFETALDRVRAG
KTESSDDLLSLFQLCGDHLSDLVAAARNGDAVEPAQAEALSRQLDEVIGSPEDTDISETDAAETFEPLTFDFDAFDDPSS
LPGIADDGAEDMRAGFNVTFVAEPELFSCGNEPALLFKALDRYGRVQVAADLDDVPSLSRLDPTMPYMKWSIDLETDATE
DVIRDVFDFVSDCAVIDIAPLDRSGPPLSELPDPIADDGPGAVEPTLPQIAPVPPVQEAIVAKVEDTSAPPTPPESSPPQ
EVGASKPTAPDAAKTTAAPQTIRVDFERVDKLINLVGELVIKEAMLSQAVEKLNLTNGNDVLQEIEGLKQLAGEIQEGVM
AIRAQPVKPLFQRMARTIRDASTTTGKRVRLTMKGEAAEVDKTVLERLVDPLNHMVRNAVDHGLESAEERIAAGKPAEGT
VTLSAAHRSGRVVIEISDDGGGINRDKVRQHAESRGLVLPDATLTPSEVDALLFMPGFSMKEEVSELSGRGVGLDVVRSE
ISALGGRMSISSELGKGTDFSISLPLTLAVLEGMVVEVAGQTMVVPITAIQETLQPSTAQIHTIGSGGRVLSIRNTLVPI
EDLGAIFGFRDTPMDLDDRVLLVIETETEKRCALIVDRLQDQRQVVIKSLETNYSHVSGIAAATILGDGRIALIVDPEDI
AGGIALPQSCQTSAPDLIASEGDQHVAS

Sequences:

>Translated_748_residues
MTVGGSDEFRASFFEECEELLEAMHDGFGLMVNGEDDDETIHVVFRAVHSIKGGSGAFGLDDLVAFAHHFETALDRVRAG
KTESSDDLLSLFQLCGDHLSDLVAAARNGDAVEPAQAEALSRQLDEVIGSPEDTDISETDAAETFEPLTFDFDAFDDPSS
LPGIADDGAEDMRAGFNVTFVAEPELFSCGNEPALLFKALDRYGRVQVAADLDDVPSLSRLDPTMPYMKWSIDLETDATE
DVIRDVFDFVSDCAVIDIAPLDRSGPPLSELPDPIADDGPGAVEPTLPQIAPVPPVQEAIVAKVEDTSAPPTPPESSPPQ
EVGASKPTAPDAAKTTAAPQTIRVDFERVDKLINLVGELVIKEAMLSQAVEKLNLTNGNDVLQEIEGLKQLAGEIQEGVM
AIRAQPVKPLFQRMARTIRDASTTTGKRVRLTMKGEAAEVDKTVLERLVDPLNHMVRNAVDHGLESAEERIAAGKPAEGT
VTLSAAHRSGRVVIEISDDGGGINRDKVRQHAESRGLVLPDATLTPSEVDALLFMPGFSMKEEVSELSGRGVGLDVVRSE
ISALGGRMSISSELGKGTDFSISLPLTLAVLEGMVVEVAGQTMVVPITAIQETLQPSTAQIHTIGSGGRVLSIRNTLVPI
EDLGAIFGFRDTPMDLDDRVLLVIETETEKRCALIVDRLQDQRQVVIKSLETNYSHVSGIAAATILGDGRIALIVDPEDI
AGGIALPQSCQTSAPDLIASEGDQHVAS
>Mature_747_residues
TVGGSDEFRASFFEECEELLEAMHDGFGLMVNGEDDDETIHVVFRAVHSIKGGSGAFGLDDLVAFAHHFETALDRVRAGK
TESSDDLLSLFQLCGDHLSDLVAAARNGDAVEPAQAEALSRQLDEVIGSPEDTDISETDAAETFEPLTFDFDAFDDPSSL
PGIADDGAEDMRAGFNVTFVAEPELFSCGNEPALLFKALDRYGRVQVAADLDDVPSLSRLDPTMPYMKWSIDLETDATED
VIRDVFDFVSDCAVIDIAPLDRSGPPLSELPDPIADDGPGAVEPTLPQIAPVPPVQEAIVAKVEDTSAPPTPPESSPPQE
VGASKPTAPDAAKTTAAPQTIRVDFERVDKLINLVGELVIKEAMLSQAVEKLNLTNGNDVLQEIEGLKQLAGEIQEGVMA
IRAQPVKPLFQRMARTIRDASTTTGKRVRLTMKGEAAEVDKTVLERLVDPLNHMVRNAVDHGLESAEERIAAGKPAEGTV
TLSAAHRSGRVVIEISDDGGGINRDKVRQHAESRGLVLPDATLTPSEVDALLFMPGFSMKEEVSELSGRGVGLDVVRSEI
SALGGRMSISSELGKGTDFSISLPLTLAVLEGMVVEVAGQTMVVPITAIQETLQPSTAQIHTIGSGGRVLSIRNTLVPIE
DLGAIFGFRDTPMDLDDRVLLVIETETEKRCALIVDRLQDQRQVVIKSLETNYSHVSGIAAATILGDGRIALIVDPEDIA
GGIALPQSCQTSAPDLIASEGDQHVAS

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=452, Percent_Identity=41.5929203539823, Blast_Score=343, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79856; Mature: 79724

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGGSDEFRASFFEECEELLEAMHDGFGLMVNGEDDDETIHVVFRAVHSIKGGSGAFGL
CCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCH
DDLVAFAHHFETALDRVRAGKTESSDDLLSLFQLCGDHLSDLVAAARNGDAVEPAQAEAL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SRQLDEVIGSPEDTDISETDAAETFEPLTFDFDAFDDPSSLPGIADDGAEDMRAGFNVTF
HHHHHHHHCCCCCCCCCCCCCHHHCCCCEEECCCCCCCCCCCCCCCCCHHHHHCCCCEEE
VAEPELFSCGNEPALLFKALDRYGRVQVAADLDDVPSLSRLDPTMPYMKWSIDLETDATE
EECCHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCCCEEEEEEECCCCHH
DVIRDVFDFVSDCAVIDIAPLDRSGPPLSELPDPIADDGPGAVEPTLPQIAPVPPVQEAI
HHHHHHHHHHHCCEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
VAKVEDTSAPPTPPESSPPQEVGASKPTAPDAAKTTAAPQTIRVDFERVDKLINLVGELV
HHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHCCCCCEEEECHHHHHHHHHHHHHHH
IKEAMLSQAVEKLNLTNGNDVLQEIEGLKQLAGEIQEGVMAIRAQPVKPLFQRMARTIRD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ASTTTGKRVRLTMKGEAAEVDKTVLERLVDPLNHMVRNAVDHGLESAEERIAAGKPAEGT
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
VTLSAAHRSGRVVIEISDDGGGINRDKVRQHAESRGLVLPDATLTPSEVDALLFMPGFSM
EEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCEECCCCCCCHHHCCEEEECCCCCH
KEEVSELSGRGVGLDVVRSEISALGGRMSISSELGKGTDFSISLPLTLAVLEGMVVEVAG
HHHHHHHCCCCCCHHHHHHHHHHHCCCCEEHHHCCCCCCEEEECCHHHHHHHHHHHEECC
QTMVVPITAIQETLQPSTAQIHTIGSGGRVLSIRNTLVPIEDLGAIFGFRDTPMDLDDRV
CEEEEEHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCE
LLVIETETEKRCALIVDRLQDQRQVVIKSLETNYSHVSGIAAATILGDGRIALIVDPEDI
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCEEEEEECCHHH
AGGIALPQSCQTSAPDLIASEGDQHVAS
CCCCCCCCCCCCCCCCHHHCCCCHHCCC
>Mature Secondary Structure 
TVGGSDEFRASFFEECEELLEAMHDGFGLMVNGEDDDETIHVVFRAVHSIKGGSGAFGL
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCH
DDLVAFAHHFETALDRVRAGKTESSDDLLSLFQLCGDHLSDLVAAARNGDAVEPAQAEAL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SRQLDEVIGSPEDTDISETDAAETFEPLTFDFDAFDDPSSLPGIADDGAEDMRAGFNVTF
HHHHHHHHCCCCCCCCCCCCCHHHCCCCEEECCCCCCCCCCCCCCCCCHHHHHCCCCEEE
VAEPELFSCGNEPALLFKALDRYGRVQVAADLDDVPSLSRLDPTMPYMKWSIDLETDATE
EECCHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCCCEEEEEEECCCCHH
DVIRDVFDFVSDCAVIDIAPLDRSGPPLSELPDPIADDGPGAVEPTLPQIAPVPPVQEAI
HHHHHHHHHHHCCEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
VAKVEDTSAPPTPPESSPPQEVGASKPTAPDAAKTTAAPQTIRVDFERVDKLINLVGELV
HHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHCCCCCEEEECHHHHHHHHHHHHHHH
IKEAMLSQAVEKLNLTNGNDVLQEIEGLKQLAGEIQEGVMAIRAQPVKPLFQRMARTIRD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ASTTTGKRVRLTMKGEAAEVDKTVLERLVDPLNHMVRNAVDHGLESAEERIAAGKPAEGT
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
VTLSAAHRSGRVVIEISDDGGGINRDKVRQHAESRGLVLPDATLTPSEVDALLFMPGFSM
EEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCEECCCCCCCHHHCCEEEECCCCCH
KEEVSELSGRGVGLDVVRSEISALGGRMSISSELGKGTDFSISLPLTLAVLEGMVVEVAG
HHHHHHHCCCCCCHHHHHHHHHHHCCCCEEHHHCCCCCCEEEECCHHHHHHHHHHHEECC
QTMVVPITAIQETLQPSTAQIHTIGSGGRVLSIRNTLVPIEDLGAIFGFRDTPMDLDDRV
CEEEEEHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCE
LLVIETETEKRCALIVDRLQDQRQVVIKSLETNYSHVSGIAAATILGDGRIALIVDPEDI
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCEEEEEECCHHH
AGGIALPQSCQTSAPDLIASEGDQHVAS
CCCCCCCCCCCCCCCCHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7494484 [H]