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The map label for this gene is cobS [H]

Identifier: 89055226

GI number: 89055226

Start: 2749307

End: 2750296

Strand: Direct

Name: cobS [H]

Synonym: Jann_2735

Alternate gene names: 89055226

Gene position: 2749307-2750296 (Clockwise)

Preceding gene: 89055225

Following gene: 89055227

Centisome position: 63.67

GC content: 60.0

Gene sequence:

>990_bases
ATGGCCGACGGCACCAGCTTGAGCATCGATGCAAAACCCACTGAGGAATTCTCGGTCCGTGAGGTCTTTGGCATCGACAC
CGATATGAAGGTGAAAGGCTTTGCCGAGCCGACTGATCGCGTGCCTGCAATTGACCCGACCTACAAGTTCGACCCCGACA
CCACCCTCGCGATCCTCGCGGGCTATGGCTACAACCGCCGCGTCATGGTGCAGGGCTACCACGGCACCGGTAAATCAACG
CATATTGAACAGGTCGGTGCACGCCTAAACTGGCCCACCGTTCGGGTGAACCTCGACAGCCACATCTCCCGCATCGACCT
GATCGGCAAGGATGCCATCAAGCTGCGCGACGGCAAGCAGGTGACGGAGTTCCACGAAGGCATCCTGCCCTGGGCCCTGC
GCAACCCCGTGGCCATCGTATTCGACGAATATGATGCAGGCCGCGCCGACGTGATGTTTGTGATCCAGCGCGTGCTGGAG
ACGGATGGCAAGCTGACCCTGATGGACCAGAACGAGATCATCACGCCCAACCCGTGCTTCCGCCTCTTTGCGACCGCCAA
CACCGTGGGTCTGGGCGACACGACGGGCCTTTACCACGGCACGCAGCAGATCAACCAGGCACAGATGGACCGCTGGTCGC
TGGTGGCGACGCTCAACTACCTGCGCCATGACGCTGAGGTGAATATCGTTCTGGCAAAATGCCCGCATTACAACACGGAA
ACCGGGCGCAAGACGATGAACCAGATGGTCACCGTGGCTGATCTGACGCGGACGGCCTTCATGAACGGAGAGCTGTCGAC
GGTGATGTCACCGCGCACGGTCATCAACTGGGCGCAAAACGCCGAGATATTCCGTGATGTGGGCTATGCCTTCCGGGTGT
CGTTCCTCAACAAATGCGACGAGCTGGAGCGCCAGACCGTGGCTGAGTTCTATCAGCGCTGCTTCGATGAAGAGCTGCCG
GAGAGTGCGGCGTCGATGTCGCTTGGCTAA

Upstream 100 bases:

>100_bases
CTTTTTGGTAGGCGCACGCGGCTACGTCCCCTTCCCCTTGCAGCCCCCCGAGATATGTTGCATCCCGACGCGACGAGATA
TTCTAGAAATTGAGGGCACC

Downstream 100 bases:

>100_bases
ACCACCGGATCCTGCCACCCCGCGCAACACACGTTTGGGGCGGTGGATCTGGGTCACGATTACCGTGATCGCTGTGGTGC
AGGTTGCGCCGTCATTGTTC

Product: hydrogenobyrinic acid a,c-diamide cobaltochelatase

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MADGTSLSIDAKPTEEFSVREVFGIDTDMKVKGFAEPTDRVPAIDPTYKFDPDTTLAILAGYGYNRRVMVQGYHGTGKST
HIEQVGARLNWPTVRVNLDSHISRIDLIGKDAIKLRDGKQVTEFHEGILPWALRNPVAIVFDEYDAGRADVMFVIQRVLE
TDGKLTLMDQNEIITPNPCFRLFATANTVGLGDTTGLYHGTQQINQAQMDRWSLVATLNYLRHDAEVNIVLAKCPHYNTE
TGRKTMNQMVTVADLTRTAFMNGELSTVMSPRTVINWAQNAEIFRDVGYAFRVSFLNKCDELERQTVAEFYQRCFDEELP
ESAASMSLG

Sequences:

>Translated_329_residues
MADGTSLSIDAKPTEEFSVREVFGIDTDMKVKGFAEPTDRVPAIDPTYKFDPDTTLAILAGYGYNRRVMVQGYHGTGKST
HIEQVGARLNWPTVRVNLDSHISRIDLIGKDAIKLRDGKQVTEFHEGILPWALRNPVAIVFDEYDAGRADVMFVIQRVLE
TDGKLTLMDQNEIITPNPCFRLFATANTVGLGDTTGLYHGTQQINQAQMDRWSLVATLNYLRHDAEVNIVLAKCPHYNTE
TGRKTMNQMVTVADLTRTAFMNGELSTVMSPRTVINWAQNAEIFRDVGYAFRVSFLNKCDELERQTVAEFYQRCFDEELP
ESAASMSLG
>Mature_328_residues
ADGTSLSIDAKPTEEFSVREVFGIDTDMKVKGFAEPTDRVPAIDPTYKFDPDTTLAILAGYGYNRRVMVQGYHGTGKSTH
IEQVGARLNWPTVRVNLDSHISRIDLIGKDAIKLRDGKQVTEFHEGILPWALRNPVAIVFDEYDAGRADVMFVIQRVLET
DGKLTLMDQNEIITPNPCFRLFATANTVGLGDTTGLYHGTQQINQAQMDRWSLVATLNYLRHDAEVNIVLAKCPHYNTET
GRKTMNQMVTVADLTRTAFMNGELSTVMSPRTVINWAQNAEIFRDVGYAFRVSFLNKCDELERQTVAEFYQRCFDEELPE
SAASMSLG

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Saccharomyces cerevisiae, GI6323135, Length=155, Percent_Identity=28.3870967741935, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI161076560, Length=203, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076562, Length=203, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 36945; Mature: 36814

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADGTSLSIDAKPTEEFSVREVFGIDTDMKVKGFAEPTDRVPAIDPTYKFDPDTTLAILA
CCCCCEEEECCCCCCCCCHHHHHCCCCCCEECCCCCCCCCCCCCCCCEEECCCCEEEEEE
GYGYNRRVMVQGYHGTGKSTHIEQVGARLNWPTVRVNLDSHISRIDLIGKDAIKLRDGKQ
CCCCCCEEEEEEECCCCCCCHHHHHCCCCCCCEEEEEHHHCCCCHHCCCCCCEEECCCCH
VTEFHEGILPWALRNPVAIVFDEYDAGRADVMFVIQRVLETDGKLTLMDQNEIITPNPCF
HHHHHCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCEECCCHHE
RLFATANTVGLGDTTGLYHGTQQINQAQMDRWSLVATLNYLRHDAEVNIVLAKCPHYNTE
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCH
TGRKTMNQMVTVADLTRTAFMNGELSTVMSPRTVINWAQNAEIFRDVGYAFRVSFLNKCD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
ELERQTVAEFYQRCFDEELPESAASMSLG
HHHHHHHHHHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure 
ADGTSLSIDAKPTEEFSVREVFGIDTDMKVKGFAEPTDRVPAIDPTYKFDPDTTLAILA
CCCCEEEECCCCCCCCCHHHHHCCCCCCEECCCCCCCCCCCCCCCCEEECCCCEEEEEE
GYGYNRRVMVQGYHGTGKSTHIEQVGARLNWPTVRVNLDSHISRIDLIGKDAIKLRDGKQ
CCCCCCEEEEEEECCCCCCCHHHHHCCCCCCCEEEEEHHHCCCCHHCCCCCCEEECCCCH
VTEFHEGILPWALRNPVAIVFDEYDAGRADVMFVIQRVLETDGKLTLMDQNEIITPNPCF
HHHHHCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCEECCCHHE
RLFATANTVGLGDTTGLYHGTQQINQAQMDRWSLVATLNYLRHDAEVNIVLAKCPHYNTE
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCH
TGRKTMNQMVTVADLTRTAFMNGELSTVMSPRTVINWAQNAEIFRDVGYAFRVSFLNKCD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
ELERQTVAEFYQRCFDEELPESAASMSLG
HHHHHHHHHHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]