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The map label for this gene is ggt [H]

Identifier: 89055128

GI number: 89055128

Start: 2651003

End: 2652790

Strand: Direct

Name: ggt [H]

Synonym: Jann_2637

Alternate gene names: 89055128

Gene position: 2651003-2652790 (Clockwise)

Preceding gene: 89055127

Following gene: 89055132

Centisome position: 61.39

GC content: 66.28

Gene sequence:

>1788_bases
ATGCGCCCCACCCTCCCCCTGATCCTTGTCGTGACCCTCAGTGCAGCCCCCGCGCTTGCGCAACAGGCCGCAGATGCCGT
GGCTCCGGAAACTGAAACGGAAACTGCCCCTTACGCCCTGTCGGACCGTGCCGCCGCTGCCATGGCCGCACGCGATGCGG
GTGATCCCGTGATGGCACAGGACTGGATGGTCGCCGCCGCCAATCCGCTGGCCGTTGAAGCCGGCGCCGATGTGCTGGCC
GCAGGCGGAACCGCCGCCGATGCCATGGTCGCTGTGCAAGCCGTGCTGGGTCTGGTGGAGCCGCAAAGTTCTGGCCTGGG
CGGTGGCGCATTTCTCGTCTGGTATGATGCGGAAAGCGGAGAGCTTACAACGCTCGACGGGCGGGAAACCGCGCCGCTTG
CCGCCACGCCGCGCCTGTTCCAGACCGAGGATAGGGAGCCGATGGGCTTCTGGGACGCCGTCGTGGGCGGCCTGTCCGTC
GGCACCCCTGGCACGCCCGCGCTGATGGAAGACGCGCACCGCCGCTGGGGCCGCGCCAACTGGGGTGATCTTCTGGATCC
GGCCATCGCGCTGGCCGATGACGGCTTCCAGGTCTCGCCGCGCATGGCAGGCTCCATCGCCAATGATGCTGAGCGTTTGT
CCACCTTCCCCGCCACTGCCGCCTATTTCCTGCCCGGCGGCACGCCTCTGGCTGAAGGCTCCACGTTGATGAACCCCGCC
TACGCCGCGACCCTGCGCGCCATGCAGACCCAAGGTGCCGATGCGATCTATGAGGGTGCTATTGCCGAAGGCATCATCGA
GACGGTCCGCAGCGCCGAGGGCAATCCCGGCGTCCTGTCGATGCGCGATCTGGACGTCTATGAGGTGATTGAGCGTCCCG
CCGTTTGCGCCGCATACCTTGATATGGACGTCTGTGGCATGGGGCCACCCTCCTCCGGCGCGCTGACCGTGGGGCAAATC
CTGGGCATATCCGGCACCTACGACCTGACCACGCCAGATGATCCCAACGCCTGGCGCATCATTGGCGACTCCTCCCGCCT
CGCCTTTGCAGACCGGGGCCGATACATGGCCGATAGCGACTATGTCCCGATGCCGACCGAAGGCCTGGTCGATCCGGCCT
ACCTGGCCGAGCGTGCCGCCCTTCTGGAGGGTGACATGGCGCTGGACGAGGTCGCCCCCGGCACACCCACCTGGGATCAC
GCGCAGCTTTGGGCCGATGACCAAAGCCTTGAATTCCCAAGCACATCTCACATCTCCATCGTCGACAGCTACGGGAATGT
CCTGTCGATGACGACAACCATTGAGAATGGCTTCGGCTCACGCCTGATGACGCCGGGCGGGTTCCTGCTCAACAATGAAC
TCACCGACTTCAGCTTTCGCACCCACGCAGACGGCGTGCCGATCGCCAACCGGCTGGAGCCCGGCAAGCGTCCGCGCTCC
TCCATGTCGCCCACCATCGTGATGCGGGACGGCGAACCGATCCTGGCTATCGGCTCGCCGGGCGGCAGCCGCATCATCGG
TTATGTGGCGACGACGATCATCGCCCATTACGAGTGGGGGCTGGACCTGCAAGACGCCATCGCTCTGCCCCACGCGGTGA
ACCGCTTCGGCACCTATGACCTTGAGGAAGGCACCGACGCCGAGGCCCTGGCCCCCGCGCTGGAAGCCATGGGGTACGAG
GTTAACGTGCGCGGCCTGACGTCGGGCCTCCACGCCATCGCCATCACGCCAGATGGCCTTGTCGGTGGCGCCGATCCGCG
CCGCGAAGGCATCGCAATCGGGGAGTAA

Upstream 100 bases:

>100_bases
CTTCCTCGGCTGATCGCCGCCGAATGGCGCGTTTGGGGCTTTACATTGCGTACCGTTACGTCACCCTCTGAGGTCTGTCC
CATAGCCCGGAGAATGCCCC

Downstream 100 bases:

>100_bases
CCGCAGACGCCTCCCAACACGAAAGCTGCCTCCGGCGGGAGTTGTAATTGCCAAGATGAAGACAGGAGCGCTCTCCCCGT
CACCTTGGCATTACAACTCC

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MRPTLPLILVVTLSAAPALAQQAADAVAPETETETAPYALSDRAAAAMAARDAGDPVMAQDWMVAAANPLAVEAGADVLA
AGGTAADAMVAVQAVLGLVEPQSSGLGGGAFLVWYDAESGELTTLDGRETAPLAATPRLFQTEDREPMGFWDAVVGGLSV
GTPGTPALMEDAHRRWGRANWGDLLDPAIALADDGFQVSPRMAGSIANDAERLSTFPATAAYFLPGGTPLAEGSTLMNPA
YAATLRAMQTQGADAIYEGAIAEGIIETVRSAEGNPGVLSMRDLDVYEVIERPAVCAAYLDMDVCGMGPPSSGALTVGQI
LGISGTYDLTTPDDPNAWRIIGDSSRLAFADRGRYMADSDYVPMPTEGLVDPAYLAERAALLEGDMALDEVAPGTPTWDH
AQLWADDQSLEFPSTSHISIVDSYGNVLSMTTTIENGFGSRLMTPGGFLLNNELTDFSFRTHADGVPIANRLEPGKRPRS
SMSPTIVMRDGEPILAIGSPGGSRIIGYVATTIIAHYEWGLDLQDAIALPHAVNRFGTYDLEEGTDAEALAPALEAMGYE
VNVRGLTSGLHAIAITPDGLVGGADPRREGIAIGE

Sequences:

>Translated_595_residues
MRPTLPLILVVTLSAAPALAQQAADAVAPETETETAPYALSDRAAAAMAARDAGDPVMAQDWMVAAANPLAVEAGADVLA
AGGTAADAMVAVQAVLGLVEPQSSGLGGGAFLVWYDAESGELTTLDGRETAPLAATPRLFQTEDREPMGFWDAVVGGLSV
GTPGTPALMEDAHRRWGRANWGDLLDPAIALADDGFQVSPRMAGSIANDAERLSTFPATAAYFLPGGTPLAEGSTLMNPA
YAATLRAMQTQGADAIYEGAIAEGIIETVRSAEGNPGVLSMRDLDVYEVIERPAVCAAYLDMDVCGMGPPSSGALTVGQI
LGISGTYDLTTPDDPNAWRIIGDSSRLAFADRGRYMADSDYVPMPTEGLVDPAYLAERAALLEGDMALDEVAPGTPTWDH
AQLWADDQSLEFPSTSHISIVDSYGNVLSMTTTIENGFGSRLMTPGGFLLNNELTDFSFRTHADGVPIANRLEPGKRPRS
SMSPTIVMRDGEPILAIGSPGGSRIIGYVATTIIAHYEWGLDLQDAIALPHAVNRFGTYDLEEGTDAEALAPALEAMGYE
VNVRGLTSGLHAIAITPDGLVGGADPRREGIAIGE
>Mature_595_residues
MRPTLPLILVVTLSAAPALAQQAADAVAPETETETAPYALSDRAAAAMAARDAGDPVMAQDWMVAAANPLAVEAGADVLA
AGGTAADAMVAVQAVLGLVEPQSSGLGGGAFLVWYDAESGELTTLDGRETAPLAATPRLFQTEDREPMGFWDAVVGGLSV
GTPGTPALMEDAHRRWGRANWGDLLDPAIALADDGFQVSPRMAGSIANDAERLSTFPATAAYFLPGGTPLAEGSTLMNPA
YAATLRAMQTQGADAIYEGAIAEGIIETVRSAEGNPGVLSMRDLDVYEVIERPAVCAAYLDMDVCGMGPPSSGALTVGQI
LGISGTYDLTTPDDPNAWRIIGDSSRLAFADRGRYMADSDYVPMPTEGLVDPAYLAERAALLEGDMALDEVAPGTPTWDH
AQLWADDQSLEFPSTSHISIVDSYGNVLSMTTTIENGFGSRLMTPGGFLLNNELTDFSFRTHADGVPIANRLEPGKRPRS
SMSPTIVMRDGEPILAIGSPGGSRIIGYVATTIIAHYEWGLDLQDAIALPHAVNRFGTYDLEEGTDAEALAPALEAMGYE
VNVRGLTSGLHAIAITPDGLVGGADPRREGIAIGE

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=544, Percent_Identity=30.3308823529412, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI73915090, Length=544, Percent_Identity=30.3308823529412, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI73915096, Length=544, Percent_Identity=30.3308823529412, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI73915094, Length=544, Percent_Identity=30.3308823529412, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI113429324, Length=562, Percent_Identity=29.0035587188612, Blast_Score=176, Evalue=8e-44,
Organism=Homo sapiens, GI113429326, Length=567, Percent_Identity=28.7477954144621, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI109148539, Length=548, Percent_Identity=29.3795620437956, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI153266885, Length=507, Percent_Identity=28.7968441814596, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI153266901, Length=510, Percent_Identity=28.6274509803922, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI153266907, Length=506, Percent_Identity=27.0750988142292, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI30581157, Length=185, Percent_Identity=35.1351351351351, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI30581155, Length=185, Percent_Identity=35.1351351351351, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI218505805, Length=186, Percent_Identity=32.258064516129, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789856, Length=554, Percent_Identity=33.7545126353791, Blast_Score=266, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI193208247, Length=576, Percent_Identity=30.7291666666667, Blast_Score=181, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI193208245, Length=576, Percent_Identity=30.7291666666667, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17542894, Length=515, Percent_Identity=30.0970873786408, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI72000294, Length=555, Percent_Identity=29.009009009009, Blast_Score=175, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI212646519, Length=555, Percent_Identity=29.009009009009, Blast_Score=175, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17506189, Length=551, Percent_Identity=27.2232304900181, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17564448, Length=433, Percent_Identity=24.7113163972286, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI72001497, Length=466, Percent_Identity=23.6051502145923, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72001495, Length=442, Percent_Identity=23.3031674208145, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323330, Length=215, Percent_Identity=26.5116279069767, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI161077496, Length=469, Percent_Identity=29.8507462686567, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI18859893, Length=458, Percent_Identity=30.5676855895196, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI45551474, Length=554, Percent_Identity=25.6317689530686, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24642670, Length=554, Percent_Identity=25.6317689530686, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24642666, Length=554, Percent_Identity=25.6317689530686, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI161077878, Length=554, Percent_Identity=25.6317689530686, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI161077880, Length=554, Percent_Identity=25.6317689530686, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI18859741, Length=476, Percent_Identity=24.1596638655462, Blast_Score=99, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 62148; Mature: 62148

Theoretical pI: Translated: 3.96; Mature: 3.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTLPLILVVTLSAAPALAQQAADAVAPETETETAPYALSDRAAAAMAARDAGDPVMAQ
CCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCEEC
DWMVAAANPLAVEAGADVLAAGGTAADAMVAVQAVLGLVEPQSSGLGGGAFLVWYDAESG
CEEEECCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC
ELTTLDGRETAPLAATPRLFQTEDREPMGFWDAVVGGLSVGTPGTPALMEDAHRRWGRAN
CEEEECCCCCCCCCCCCCHHCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
WGDLLDPAIALADDGFQVSPRMAGSIANDAERLSTFPATAAYFLPGGTPLAEGSTLMNPA
CHHHHCCHHEEECCCCEECCHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHH
YAATLRAMQTQGADAIYEGAIAEGIIETVRSAEGNPGVLSMRDLDVYEVIERPAVCAAYL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCEEHHH
DMDVCGMGPPSSGALTVGQILGISGTYDLTTPDDPNAWRIIGDSSRLAFADRGRYMADSD
CCHHCCCCCCCCCCEEEHHHEECCCEECCCCCCCCCCEEEEECCCCEEEECCCCEECCCC
YVPMPTEGLVDPAYLAERAALLEGDMALDEVAPGTPTWDHAQLWADDQSLEFPSTSHISI
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCEEE
VDSYGNVLSMTTTIENGFGSRLMTPGGFLLNNELTDFSFRTHADGVPIANRLEPGKRPRS
EECCCCEEEEEEECCCCCCCCCCCCCCEEECCCCCCCEEEECCCCCCCHHCCCCCCCCCC
SMSPTIVMRDGEPILAIGSPGGSRIIGYVATTIIAHYEWGLDLQDAIALPHAVNRFGTYD
CCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
LEEGTDAEALAPALEAMGYEVNVRGLTSGLHAIAITPDGLVGGADPRREGIAIGE
CCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRPTLPLILVVTLSAAPALAQQAADAVAPETETETAPYALSDRAAAAMAARDAGDPVMAQ
CCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCEEC
DWMVAAANPLAVEAGADVLAAGGTAADAMVAVQAVLGLVEPQSSGLGGGAFLVWYDAESG
CEEEECCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC
ELTTLDGRETAPLAATPRLFQTEDREPMGFWDAVVGGLSVGTPGTPALMEDAHRRWGRAN
CEEEECCCCCCCCCCCCCHHCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
WGDLLDPAIALADDGFQVSPRMAGSIANDAERLSTFPATAAYFLPGGTPLAEGSTLMNPA
CHHHHCCHHEEECCCCEECCHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHH
YAATLRAMQTQGADAIYEGAIAEGIIETVRSAEGNPGVLSMRDLDVYEVIERPAVCAAYL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCEEHHH
DMDVCGMGPPSSGALTVGQILGISGTYDLTTPDDPNAWRIIGDSSRLAFADRGRYMADSD
CCHHCCCCCCCCCCEEEHHHEECCCEECCCCCCCCCCEEEEECCCCEEEECCCCEECCCC
YVPMPTEGLVDPAYLAERAALLEGDMALDEVAPGTPTWDHAQLWADDQSLEFPSTSHISI
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCEEE
VDSYGNVLSMTTTIENGFGSRLMTPGGFLLNNELTDFSFRTHADGVPIANRLEPGKRPRS
EECCCCEEEEEEECCCCCCCCCCCCCCEEECCCCCCCEEEECCCCCCCHHCCCCCCCCCC
SMSPTIVMRDGEPILAIGSPGGSRIIGYVATTIIAHYEWGLDLQDAIALPHAVNRFGTYD
CCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
LEEGTDAEALAPALEAMGYEVNVRGLTSGLHAIAITPDGLVGGADPRREGIAIGE
CCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA