BacMap

Definition	Jannaschia sp. CCS1 chromosome, complete genome.
Accession	NC_007802
Length	4,317,977

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The map label for this gene is hbdH1 [H]

Identifier: 89055106

GI number: 89055106

Start: 2634301

End: 2635074

Strand: Direct

Name: hbdH1 [H]

Synonym: Jann_2615

Alternate gene names: 89055106

Gene position: 2634301-2635074 (Clockwise)

Preceding gene: 89055102

Following gene: 89055108

Centisome position: 61.01

GC content: 60.34

Gene sequence:

>774_bases
ATGACATCAGGTCACAAAACGGCAATCGTAACAGGTGGCTTGTCCGGGATGGGGCTCGCGATTGCGCGGCGGCTGGCGCG
TGACGGGACAACCGTTGTGATCGGTGCGCGCAGTGCGGGCGACACGGATTACGTGAAAGATGTTCTGGGAACCGATGCGG
ATGGTCTTCACGCCGAACAACTGGATGTCCAATCGCACGAAAGTGTCGATGGGTTTGTTGCAAGCGTGGTCAAGACCCAC
GGCGGTGTCGACATTCTGGTCAACGCAGCCGGCGTTTACGAGGAGGCCGCCGTGATTGATCACCCCGAGCAGATCTGGGA
CGACCACATCAACACGAACCTCAGCGGCACATTCCGCACGATCCGTGCCGTGATGCCCCATATGAAGCGTGCGGGCTGGG
GGCGGATCATAAACATGGCGTCGGTCGCCGCGCATAATGGGATGGCCAACAACGCGGCCTATTGCGCCTCCAAAGCCGGG
CTTTTGGGGTTGGGACGTTGTGTGGCGTTGGAAGGGGCGGCCCATGGCGTGACCTGTGTGTCGATCAGTCCGACCTGGGT
TGAAACGGAAATGCTGCGTCGGTTTATTGACGCGGATATGAAGGCCACGGGTCAGACGCTGGAGGACGTGAGGGCCGAAT
ACGCAAAGTCGAACCCGCAAAACCAGCTTGTTCAGCCCACCGAAGTGGCCGAGCTTGCCGCCTTTCTGGCCAGCGACGCC
GCCCGCGCGCTGACCATGGAAGATTATCAGGTCAACGCGGGATCGCTTTGGTAG

Upstream 100 bases:

>100_bases
CTGGACACCTGCGCAACGCGCGGCCACGAATGACCGTGCACCCACGCAAGATCCGGCGTAAACACCCGGTAATTCGGAAC
TTTGCCAGAGGTAGCGCAGC

Downstream 100 bases:

>100_bases
TCGCGGGCGCGGCGCGTTAGCAGGGCTTCGCTGTCACTGATTTCGTTGAATGGAAGGGCGCTGACCCGTTCCCAAGCAGC
ACGGGCGGCTGTGTTCTCAA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTSGHKTAIVTGGLSGMGLAIARRLARDGTTVVIGARSAGDTDYVKDVLGTDADGLHAEQLDVQSHESVDGFVASVVKTH
GGVDILVNAAGVYEEAAVIDHPEQIWDDHINTNLSGTFRTIRAVMPHMKRAGWGRIINMASVAAHNGMANNAAYCASKAG
LLGLGRCVALEGAAHGVTCVSISPTWVETEMLRRFIDADMKATGQTLEDVRAEYAKSNPQNQLVQPTEVAELAAFLASDA
ARALTMEDYQVNAGSLW

Sequences:

>Translated_257_residues
MTSGHKTAIVTGGLSGMGLAIARRLARDGTTVVIGARSAGDTDYVKDVLGTDADGLHAEQLDVQSHESVDGFVASVVKTH
GGVDILVNAAGVYEEAAVIDHPEQIWDDHINTNLSGTFRTIRAVMPHMKRAGWGRIINMASVAAHNGMANNAAYCASKAG
LLGLGRCVALEGAAHGVTCVSISPTWVETEMLRRFIDADMKATGQTLEDVRAEYAKSNPQNQLVQPTEVAELAAFLASDA
ARALTMEDYQVNAGSLW
>Mature_256_residues
TSGHKTAIVTGGLSGMGLAIARRLARDGTTVVIGARSAGDTDYVKDVLGTDADGLHAEQLDVQSHESVDGFVASVVKTHG
GVDILVNAAGVYEEAAVIDHPEQIWDDHINTNLSGTFRTIRAVMPHMKRAGWGRIINMASVAAHNGMANNAAYCASKAGL
LGLGRCVALEGAAHGVTCVSISPTWVETEMLRRFIDADMKATGQTLEDVRAEYAKSNPQNQLVQPTEVAELAAFLASDAA
RALTMEDYQVNAGSLW

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=29.6442687747036, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI66933014, Length=222, Percent_Identity=30.1801801801802, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI5031737, Length=192, Percent_Identity=33.8541666666667, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI33667109, Length=209, Percent_Identity=32.5358851674641, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI126723191, Length=174, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=27.4509803921569, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI40254992, Length=233, Percent_Identity=29.1845493562232, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=29.296875, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=27.5471698113208, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI4504505, Length=222, Percent_Identity=27.4774774774775, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4758504, Length=199, Percent_Identity=34.1708542713568, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7657478, Length=227, Percent_Identity=29.9559471365639, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI40254986, Length=164, Percent_Identity=28.6585365853659, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI40807363, Length=189, Percent_Identity=26.984126984127, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=26.7326732673267, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI223718074, Length=208, Percent_Identity=29.8076923076923, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI109715829, Length=244, Percent_Identity=26.6393442622951, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI83715985, Length=184, Percent_Identity=34.7826086956522, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI59889578, Length=185, Percent_Identity=27.5675675675676, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI302344755, Length=102, Percent_Identity=34.3137254901961, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=23.3502538071066, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=36.5461847389558, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=33.8645418326693, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790717, Length=236, Percent_Identity=27.5423728813559, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786812, Length=173, Percent_Identity=34.1040462427746, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789208, Length=239, Percent_Identity=29.2887029288703, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87082160, Length=188, Percent_Identity=30.3191489361702, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788459, Length=256, Percent_Identity=27.734375, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787820, Length=157, Percent_Identity=34.3949044585987, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=27.3092369477912, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789057, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=29.5546558704453, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=26.7441860465116, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28.8, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=31.1740890688259, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=28.0155642023346, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=29.1338582677165, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=25.6, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17568967, Length=210, Percent_Identity=29.0476190476191, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=256, Percent_Identity=29.296875, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=25.6, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=241, Percent_Identity=28.2157676348548, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=241, Percent_Identity=26.9709543568465, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=25.2631578947368, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=27.979274611399, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=27.979274611399, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=247, Percent_Identity=25.5060728744939, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=247, Percent_Identity=27.1255060728745, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=248, Percent_Identity=26.2096774193548, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=244, Percent_Identity=27.0491803278689, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=200, Percent_Identity=33, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=243, Percent_Identity=27.5720164609054, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=247, Percent_Identity=27.9352226720648, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=24.2105263157895, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=241, Percent_Identity=27.8008298755187, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=242, Percent_Identity=28.099173553719, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=204, Percent_Identity=25, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=248, Percent_Identity=28.6290322580645, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=28.1746031746032, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=242, Percent_Identity=26.0330578512397, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=248, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=248, Percent_Identity=27.8225806451613, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=25.6544502617801, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=247, Percent_Identity=25.5060728744939, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=29.2553191489362, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=26.9035532994924, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322779, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320089, Length=204, Percent_Identity=25.9803921568627, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=32.6771653543307, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24639444, Length=236, Percent_Identity=32.2033898305085, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=32.6771653543307, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859837, Length=187, Percent_Identity=32.620320855615, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17737361, Length=239, Percent_Identity=31.3807531380753, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21355319, Length=243, Percent_Identity=25.9259259259259, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=29.2, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24665243, Length=202, Percent_Identity=27.2277227722772, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221331218, Length=202, Percent_Identity=27.2277227722772, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21358495, Length=190, Percent_Identity=27.8947368421053, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24643142, Length=186, Percent_Identity=30.1075268817204, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24665247, Length=203, Percent_Identity=27.0935960591133, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221331216, Length=203, Percent_Identity=27.0935960591133, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356301, Length=198, Percent_Identity=29.2929292929293, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28571387, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28573296, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24586328, Length=206, Percent_Identity=27.1844660194175, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076371, Length=230, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=24.3523316062176, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI221510726, Length=218, Percent_Identity=28.4403669724771, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27160; Mature: 27029

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGHKTAIVTGGLSGMGLAIARRLARDGTTVVIGARSAGDTDYVKDVLGTDADGLHAEQ
CCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHH
LDVQSHESVDGFVASVVKTHGGVDILVNAAGVYEEAAVIDHPEQIWDDHINTNLSGTFRT
HCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCHHHHHHHHCCCCCCHHHHH
IRAVMPHMKRAGWGRIINMASVAAHNGMANNAAYCASKAGLLGLGRCVALEGAAHGVTCV
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHCCHHEEECCCCCCEEEE
SISPTWVETEMLRRFIDADMKATGQTLEDVRAEYAKSNPQNQLVQPTEVAELAAFLASDA
ECCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHH
ARALTMEDYQVNAGSLW
HHHEEECCEECCCCCCC
>Mature Secondary Structure 
TSGHKTAIVTGGLSGMGLAIARRLARDGTTVVIGARSAGDTDYVKDVLGTDADGLHAEQ
CCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHH
LDVQSHESVDGFVASVVKTHGGVDILVNAAGVYEEAAVIDHPEQIWDDHINTNLSGTFRT
HCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCHHHHHHHHCCCCCCHHHHH
IRAVMPHMKRAGWGRIINMASVAAHNGMANNAAYCASKAGLLGLGRCVALEGAAHGVTCV
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHCCHHEEECCCCCCEEEE
SISPTWVETEMLRRFIDADMKATGQTLEDVRAEYAKSNPQNQLVQPTEVAELAAFLASDA
ECCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHH
ARALTMEDYQVNAGSLW
HHHEEECCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA