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The map label for this gene is yedX [C]

Identifier: 89055100

GI number: 89055100

Start: 2625447

End: 2625803

Strand: Direct

Name: yedX [C]

Synonym: Jann_2609

Alternate gene names: 89055100

Gene position: 2625447-2625803 (Clockwise)

Preceding gene: 89055096

Following gene: 89055102

Centisome position: 60.8

GC content: 60.78

Gene sequence:

>357_bases
ATGGCGGGCTATTTGACTACCCACGTTCTCGACACGGCCAAGGGCTGCCCGGCCAGTGGCATCCAGATTGCGCTGTACCG
GGTGTCCGGGAACTCGCACCGTATAATCGCGGAGGCTGTGACGAATGCGGATGGGCGCACCGATGCGCCAATCCTGCCAT
CGGACAAGTTCGAACCCGGATCGTATGAGCTGATCTTCTTTGCGGGTGACTACCTGCGCCAGCCCGGCCAACCGGACGAC
ACGATCCTGTTCCTGGACCAAATCCCGATCCGCTTCGGCATGTCCGACGCAGACGCCCATTACCATGTGCCGCTTCTGCT
TTCGCCCTTCGGATATTCCACCTATCGCGGCAGCTGA

Upstream 100 bases:

>100_bases
ATTTTTCAAATTATTCTTGAAGGAGCCTTCGGTCCACCTTGCTTTGCACCGCCCCCTCTGGCCTCTCTATAAGGGCATAG
ATCAATGGAAAGGACACGCG

Downstream 100 bases:

>100_bases
CCCAGCTTTTCGGCCTGCCGCACCAGATCGCCAATGCGGTTGATCACGAATTCCATGAAGAGCCGCGTCTTCGGATCCTG
CATCCGGCGATGGGTGAACA

Product: transthyretin

Products: NA

Alternate protein names: HIU hydrolase; HIUHase [H]

Number of amino acids: Translated: 118; Mature: 117

Protein sequence:

>118_residues
MAGYLTTHVLDTAKGCPASGIQIALYRVSGNSHRIIAEAVTNADGRTDAPILPSDKFEPGSYELIFFAGDYLRQPGQPDD
TILFLDQIPIRFGMSDADAHYHVPLLLSPFGYSTYRGS

Sequences:

>Translated_118_residues
MAGYLTTHVLDTAKGCPASGIQIALYRVSGNSHRIIAEAVTNADGRTDAPILPSDKFEPGSYELIFFAGDYLRQPGQPDD
TILFLDQIPIRFGMSDADAHYHVPLLLSPFGYSTYRGS
>Mature_117_residues
AGYLTTHVLDTAKGCPASGIQIALYRVSGNSHRIIAEAVTNADGRTDAPILPSDKFEPGSYELIFFAGDYLRQPGQPDDT
ILFLDQIPIRFGMSDADAHYHVPLLLSPFGYSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=114, Percent_Identity=36.8421052631579, Blast_Score=86, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI115532922, Length=114, Percent_Identity=37.719298245614, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115532920, Length=114, Percent_Identity=37.719298245614, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115534555, Length=114, Percent_Identity=37.719298245614, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24652571, Length=118, Percent_Identity=34.7457627118644, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 12865; Mature: 12733

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00768 TRANSTHYRETIN_1 ; PS00769 TRANSTHYRETIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGYLTTHVLDTAKGCPASGIQIALYRVSGNSHRIIAEAVTNADGRTDAPILPSDKFEPG
CCCCEEHHEECCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
SYELIFFAGDYLRQPGQPDDTILFLDQIPIRFGMSDADAHYHVPLLLSPFGYSTYRGS
CEEEEEEECHHHCCCCCCCCEEEEEECCCEEECCCCCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
AGYLTTHVLDTAKGCPASGIQIALYRVSGNSHRIIAEAVTNADGRTDAPILPSDKFEPG
CCCEEHHEECCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
SYELIFFAGDYLRQPGQPDDTILFLDQIPIRFGMSDADAHYHVPLLLSPFGYSTYRGS
CEEEEEEECHHHCCCCCCCCEEEEEECCCEEECCCCCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]