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The map label for this gene is xerD [H]

Identifier: 89054975

GI number: 89054975

Start: 2480121

End: 2481035

Strand: Reverse

Name: xerD [H]

Synonym: Jann_2484

Alternate gene names: 89054975

Gene position: 2481035-2480121 (Counterclockwise)

Preceding gene: 89054976

Following gene: 89054974

Centisome position: 57.46

GC content: 67.43

Gene sequence:

>915_bases
ATGCGCGCGCCAGCCCAGGACATGGATTGGATCGCCCTCTATCTGGACGCCGCCGCTGCCGAGCAGGGGGCCGCGCGCAA
CACGCTTCTGGCCTATGGGCGCGACCTGAAGGACGCCATGATGTCGGTTCGTAAATCCGGCGGATTTGCCGGCGCCGACC
GTGCCGCATTGGAGGCCTATATTGCCGGGCTTGAGGCCCAGGGGCTGGCCGCGGCCACCCGGGCGCGCCGGTTATCCTCG
CTCAAACAACTCTACCGCTTCGCCCATGAGGAGGGGTGGCGCGAGGACAACCCGACCTTGCAAATCACCGGTCCCGCGCG
CACCCGCAAGCTGCCCGGCACCCTGTCGCTGGAGGAGGTCGACGCGCTGCTGGAGGCCTCCGCCACCTATGGCCGCAATG
ATGCCGACCGCTTGCGCAATCATTGCCTGATGCAGATCCTCTACGCCACGGGCCTGCGCGTGACAGAACTGGTGTCGCTG
CCCATCACGGCGCTGCGGGGCGATCCGAACATGCTGCTGGTCCTGGGCAAGGGCGGGAAGGAGCGGATGGTCCCCCTGTC
GCCGCCCGCGCGCACGGCCATGGCCGCCTGGCTGGACCATCTTGACGCAACGCAGGAGGAGCCGCGCAGCCTGTTTGCGT
TTCCCTCCCACGGCAAATCCGGCCACCTCACGCGGGTGCGGTTCTTCACCCTGATCAAGGAGTTAAGCGCCAGCGCGGGC
ATCGACCCCGCCCGCGTCACGCCCCACACCCTGCGCCATGCCTTCGCCACGCATCTGTTGCAGAACGGGGCGGACCTGCG
CGCGATCCAGACGCTTCTGGGCCATGCCGATATCGCCACGACCGAGATCTATACCCACATCCTGGATGAACGCCTGCGCC
AGTTGGTCCTGGACCATCATCCCCTGGCGCGGTGA

Upstream 100 bases:

>100_bases
CAATGATCTGACCGATGCGCTGGTCCTCTTCCGGTCCGTCGGGCTGGAGGACGTCGCCCGCCGCACCGCGCTGCAATTGC
TGCTGCTGGAGCGCTAGGGG

Downstream 100 bases:

>100_bases
GCGTCCCGGAGACCGCCTGCACCCCTTGAACGGCCTGCCCCGCACGCCCATAACCAACCTATGGAAAACGATATCCCCTT
CTTCAACACCGCCGCCTTTC

Product: phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MRAPAQDMDWIALYLDAAAAEQGAARNTLLAYGRDLKDAMMSVRKSGGFAGADRAALEAYIAGLEAQGLAAATRARRLSS
LKQLYRFAHEEGWREDNPTLQITGPARTRKLPGTLSLEEVDALLEASATYGRNDADRLRNHCLMQILYATGLRVTELVSL
PITALRGDPNMLLVLGKGGKERMVPLSPPARTAMAAWLDHLDATQEEPRSLFAFPSHGKSGHLTRVRFFTLIKELSASAG
IDPARVTPHTLRHAFATHLLQNGADLRAIQTLLGHADIATTEIYTHILDERLRQLVLDHHPLAR

Sequences:

>Translated_304_residues
MRAPAQDMDWIALYLDAAAAEQGAARNTLLAYGRDLKDAMMSVRKSGGFAGADRAALEAYIAGLEAQGLAAATRARRLSS
LKQLYRFAHEEGWREDNPTLQITGPARTRKLPGTLSLEEVDALLEASATYGRNDADRLRNHCLMQILYATGLRVTELVSL
PITALRGDPNMLLVLGKGGKERMVPLSPPARTAMAAWLDHLDATQEEPRSLFAFPSHGKSGHLTRVRFFTLIKELSASAG
IDPARVTPHTLRHAFATHLLQNGADLRAIQTLLGHADIATTEIYTHILDERLRQLVLDHHPLAR
>Mature_304_residues
MRAPAQDMDWIALYLDAAAAEQGAARNTLLAYGRDLKDAMMSVRKSGGFAGADRAALEAYIAGLEAQGLAAATRARRLSS
LKQLYRFAHEEGWREDNPTLQITGPARTRKLPGTLSLEEVDALLEASATYGRNDADRLRNHCLMQILYATGLRVTELVSL
PITALRGDPNMLLVLGKGGKERMVPLSPPARTAMAAWLDHLDATQEEPRSLFAFPSHGKSGHLTRVRFFTLIKELSASAG
IDPARVTPHTLRHAFATHLLQNGADLRAIQTLLGHADIATTEIYTHILDERLRQLVLDHHPLAR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=300, Percent_Identity=40.6666666666667, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=31.864406779661, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1790768, Length=177, Percent_Identity=32.7683615819209, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33362; Mature: 33362

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAPAQDMDWIALYLDAAAAEQGAARNTLLAYGRDLKDAMMSVRKSGGFAGADRAALEAY
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHH
IAGLEAQGLAAATRARRLSSLKQLYRFAHEEGWREDNPTLQITGPARTRKLPGTLSLEEV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHCCCCCCCCHHHH
DALLEASATYGRNDADRLRNHCLMQILYATGLRVTELVSLPITALRGDPNMLLVLGKGGK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHEECCCCCEEEEEECCCC
ERMVPLSPPARTAMAAWLDHLDATQEEPRSLFAFPSHGKSGHLTRVRFFTLIKELSASAG
CCCCCCCCCHHHHHHHHHHHHCCCHHCCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
IDPARVTPHTLRHAFATHLLQNGADLRAIQTLLGHADIATTEIYTHILDERLRQLVLDHH
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
PLAR
CCCC
>Mature Secondary Structure
MRAPAQDMDWIALYLDAAAAEQGAARNTLLAYGRDLKDAMMSVRKSGGFAGADRAALEAY
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHH
IAGLEAQGLAAATRARRLSSLKQLYRFAHEEGWREDNPTLQITGPARTRKLPGTLSLEEV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHCCCCCCCCHHHH
DALLEASATYGRNDADRLRNHCLMQILYATGLRVTELVSLPITALRGDPNMLLVLGKGGK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHEECCCCCEEEEEECCCC
ERMVPLSPPARTAMAAWLDHLDATQEEPRSLFAFPSHGKSGHLTRVRFFTLIKELSASAG
CCCCCCCCCHHHHHHHHHHHHCCCHHCCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
IDPARVTPHTLRHAFATHLLQNGADLRAIQTLLGHADIATTEIYTHILDERLRQLVLDHH
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
PLAR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]