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The map label for this gene is yhdH [H]

Identifier: 89054869

GI number: 89054869

Start: 2382001

End: 2383005

Strand: Reverse

Name: yhdH [H]

Synonym: Jann_2378

Alternate gene names: 89054869

Gene position: 2383005-2382001 (Counterclockwise)

Preceding gene: 89054870

Following gene: 89054867

Centisome position: 55.19

GC content: 64.48

Gene sequence:

>1005_bases
ATGACGTTCAATGCATTGGTCGTTGAGAAAAATGATGAGGGCAAGACCAGCGCCTCTGTCGAAGCCATATCCGAAGACCG
CCTGCCCACGTTTGAGGATGGCGGCAATGTGACGGTCGCCGTCGACTATTCAACGTTAAACTATAAGGACGGGCTCTGCG
TCGGCCCCGGTGGCGGGTTGGTTCGCAAATATCCCCACGTGCCGGGCATTGATTTCGCGGGCACCGTAGAGACGTCCGAC
GATGACCGCTACAAACCCGGCGACAAGGTCGTGCTGACCGGATGGCGCGTGGGGGAGATGCACTGGGGCGGCTATGCCCA
GAAAGCCCGCGTGAAGGCCGATTGGCTGGTGCCGCTGCCCGAGGGTCTGACGACGCGGCAGGCGATGGCCATTGGCACCG
CAGGTTTCACCGCGATGCTGGCGATCATGGCGCTGGAGGACCACGGATTGAAGCCCGATCAGGGGGAGGTTCTGGTGACC
GGCGCGGCTGGCGGCGTCGGGTCCGTTGCCACAGCGATCCTGGCCAATTTCGGTCATGAGGTCGCGGCAGTAACAGGCCG
ACCCGAGCAGGAGGACTACCTGAAGTCGCTGGGGGCCACCCGCATCGTCGCCCGCGAAGAGATCAACGAGACGGTCAAAC
GCCCGCTGGAGGCCGAGACCTGGGCCGGATGCGTCGATGCCGTGGGCGGCGACATGCTGGCGCGGGTGTTGGGGCAGATG
AAATACGGCGGCTCCGTCGCGGCGGTGGGTCTGGCGGGCGGCGCGGGCCTTCCGGCGACGGTGATCCCGTTCCTTCTGCG
CGGCGTAAACCTTCTTGGCATCGACAGCGTCATGCAGCCCTATGACAACCGGGTGCGCGCGTGGAATTTCCTCGCCAAGG
ATCTGCCGATGGGCAAGTTGGAGGCCATGGTCGTGCCCGCGACGCTGTCCGATCTGCCGGATCTTGGTCGCGCCATCCTC
AAGGGCGGTGTTCGGGGCCGTGTTGTCGTCGACGTGAATGCGTGA

Upstream 100 bases:

>100_bases
CCCGATGGCCTGATGCCCGCAGAGGTGCGTGAGAAATTTTGGATTTGATTACAGCACTTTGCGCTGCGATCTTAACGCGA
TACTGAAGGAGAGAGACGCG

Downstream 100 bases:

>100_bases
CGCCTGGCCCGGGACGTGCGGGGCAAATTGATCTACCATTGATCTACCCCGCGCTCTGGGACCCTGTGCTGGGACCCCAT
GTCGGCAATTGATATACGAT

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTFNALVVEKNDEGKTSASVEAISEDRLPTFEDGGNVTVAVDYSTLNYKDGLCVGPGGGLVRKYPHVPGIDFAGTVETSD
DDRYKPGDKVVLTGWRVGEMHWGGYAQKARVKADWLVPLPEGLTTRQAMAIGTAGFTAMLAIMALEDHGLKPDQGEVLVT
GAAGGVGSVATAILANFGHEVAAVTGRPEQEDYLKSLGATRIVAREEINETVKRPLEAETWAGCVDAVGGDMLARVLGQM
KYGGSVAAVGLAGGAGLPATVIPFLLRGVNLLGIDSVMQPYDNRVRAWNFLAKDLPMGKLEAMVVPATLSDLPDLGRAIL
KGGVRGRVVVDVNA

Sequences:

>Translated_334_residues
MTFNALVVEKNDEGKTSASVEAISEDRLPTFEDGGNVTVAVDYSTLNYKDGLCVGPGGGLVRKYPHVPGIDFAGTVETSD
DDRYKPGDKVVLTGWRVGEMHWGGYAQKARVKADWLVPLPEGLTTRQAMAIGTAGFTAMLAIMALEDHGLKPDQGEVLVT
GAAGGVGSVATAILANFGHEVAAVTGRPEQEDYLKSLGATRIVAREEINETVKRPLEAETWAGCVDAVGGDMLARVLGQM
KYGGSVAAVGLAGGAGLPATVIPFLLRGVNLLGIDSVMQPYDNRVRAWNFLAKDLPMGKLEAMVVPATLSDLPDLGRAIL
KGGVRGRVVVDVNA
>Mature_333_residues
TFNALVVEKNDEGKTSASVEAISEDRLPTFEDGGNVTVAVDYSTLNYKDGLCVGPGGGLVRKYPHVPGIDFAGTVETSDD
DRYKPGDKVVLTGWRVGEMHWGGYAQKARVKADWLVPLPEGLTTRQAMAIGTAGFTAMLAIMALEDHGLKPDQGEVLVTG
AAGGVGSVATAILANFGHEVAAVTGRPEQEDYLKSLGATRIVAREEINETVKRPLEAETWAGCVDAVGGDMLARVLGQMK
YGGSVAAVGLAGGAGLPATVIPFLLRGVNLLGIDSVMQPYDNRVRAWNFLAKDLPMGKLEAMVVPATLSDLPDLGRAILK
GGVRGRVVVDVNA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=194, Percent_Identity=30.9278350515464, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI13236495, Length=194, Percent_Identity=30.9278350515464, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789651, Length=331, Percent_Identity=53.7764350453172, Blast_Score=357, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35102; Mature: 34970

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFNALVVEKNDEGKTSASVEAISEDRLPTFEDGGNVTVAVDYSTLNYKDGLCVGPGGGL
CCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCEEECCCCCC
VRKYPHVPGIDFAGTVETSDDDRYKPGDKVVLTGWRVGEMHWGGYAQKARVKADWLVPLP
HHCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCEECCCCCCCCEEEEEEEEECC
EGLTTRQAMAIGTAGFTAMLAIMALEDHGLKPDQGEVLVTGAAGGVGSVATAILANFGHE
CCCCHHHHHEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCC
VAAVTGRPEQEDYLKSLGATRIVAREEINETVKRPLEAETWAGCVDAVGGDMLARVLGQM
EEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHH
KYGGSVAAVGLAGGAGLPATVIPFLLRGVNLLGIDSVMQPYDNRVRAWNFLAKDLPMGKL
CCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHCHHHHHHHHHHCCCCCCE
EAMVVPATLSDLPDLGRAILKGGVRGRVVVDVNA
EEEEECHHHHCCHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure 
TFNALVVEKNDEGKTSASVEAISEDRLPTFEDGGNVTVAVDYSTLNYKDGLCVGPGGGL
CCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCEEECCCCCC
VRKYPHVPGIDFAGTVETSDDDRYKPGDKVVLTGWRVGEMHWGGYAQKARVKADWLVPLP
HHCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCEECCCCCCCCEEEEEEEEECC
EGLTTRQAMAIGTAGFTAMLAIMALEDHGLKPDQGEVLVTGAAGGVGSVATAILANFGHE
CCCCHHHHHEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCC
VAAVTGRPEQEDYLKSLGATRIVAREEINETVKRPLEAETWAGCVDAVGGDMLARVLGQM
EEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHH
KYGGSVAAVGLAGGAGLPATVIPFLLRGVNLLGIDSVMQPYDNRVRAWNFLAKDLPMGKL
CCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHCHHHHHHHHHHCCCCCCE
EAMVVPATLSDLPDLGRAILKGGVRGRVVVDVNA
EEEEECHHHHCCHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370469; 9278503 [H]