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The map label for this gene is argC

Identifier: 89054827

GI number: 89054827

Start: 2343346

End: 2344374

Strand: Reverse

Name: argC

Synonym: Jann_2336

Alternate gene names: 89054827

Gene position: 2344374-2343346 (Counterclockwise)

Preceding gene: 89054828

Following gene: 89054826

Centisome position: 54.29

GC content: 62.39

Gene sequence:

>1029_bases
ATGACCAAGAAAATCGCGATCCTCGGGGCCTCCGGCTATACGGGCGCGGAGCTGTGCCGATTGATCGCAGGCCACCCGGA
TATGACGATTGTGGCGCTGACCGGTGATCGGAAGGCGGGGCAGCCCATGGCCTCGGTCTATCCGTTCCTGCGCGGGGCCG
GATTGCCCGATCTGGTGCGGATTGAGGATGTGGATTTCTCTGGGGTTGATCTGGCGTTCTGTGCCTTGCCGCATGCCACA
TCCCAAAGCGTTATCAAGGCCTTGCCTGCCGACCTTAAAGTTGTGGATCTTTCTGCCGACTTTCGCCTGCGCGACCCTGC
CGACTACGCCAAATGGTATGGCAAGGATCACGACGCGCCGGCGCTTCAAAAGCAGGCCATCTATGGCCTGACCGAGTTCT
ACCGTGATCAGATCCGCGATGCGCGGCTGGTGGCGGGGACCGGGTGCAATGCGGCCACCGGGCAATTCGCCCTGCGGCCC
CTGATCGAGAACGGTGTCGTGGATCTCGACGACATCATCATTGATCTCATTTGCGGTGTGTCGGGCGCGGGGCGGGCGTT
GAAGGAAAACCTGCTGCATGCGGAACTGAGCGAAGGCACCCACGCCTATGCGCTAGGCGGCACCCACCGGCATCTGGGCG
AGTTTGACCAGGAATTCAGCAAGGTGGCGGGCCGCAAGGTGGAGGTTCAGTTCACTCCCCATCTGGCGCCGTTCAACCGT
GGCATCCTCGCCACCTGCTATGTGAAGGGCGACGCGCAGGCGATCCACGCCACGCTCACGGCCGCTTACCGCGGTGAGAT
GTTCATCGAAGTGCTGCCTTTTGGCGCGGCCCCCTCGACACATGACGTGCGGGGCACCAATTATTGTCATATTGGTGTTG
TGGCCGACCGGCGCAGCGGACGGGCTCAGATCGTCGCGGCGCTGGATAATTTGTGCAAGGGATCCAGCGGGCAGGCGGTG
CAGAACGCCAACCTGATGCTGGGGCTGGAGGAGACAGCGGGCCTGTTGGGTCTGGGTGTGTTCCCCTGA

Upstream 100 bases:

>100_bases
GAAGTTGTTTTCGATTTGTTATACCCCGATCAGTAACCTTGATTTGAACGCCCGCGCGTTATGGCTTATGGGTCGCGGCA
CATCTTCAGGGACCTCTGCC

Downstream 100 bases:

>100_bases
GGGAGACGACGCGATGCGCGGGTTGAAGAAGCAACGCAGGATCCAGATCCTGATCGTCGCGGCGGTGGCGCTGACCCTGT
CGTCCGTGCTGATCGGGTAT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTKKIAILGASGYTGAELCRLIAGHPDMTIVALTGDRKAGQPMASVYPFLRGAGLPDLVRIEDVDFSGVDLAFCALPHAT
SQSVIKALPADLKVVDLSADFRLRDPADYAKWYGKDHDAPALQKQAIYGLTEFYRDQIRDARLVAGTGCNAATGQFALRP
LIENGVVDLDDIIIDLICGVSGAGRALKENLLHAELSEGTHAYALGGTHRHLGEFDQEFSKVAGRKVEVQFTPHLAPFNR
GILATCYVKGDAQAIHATLTAAYRGEMFIEVLPFGAAPSTHDVRGTNYCHIGVVADRRSGRAQIVAALDNLCKGSSGQAV
QNANLMLGLEETAGLLGLGVFP

Sequences:

>Translated_342_residues
MTKKIAILGASGYTGAELCRLIAGHPDMTIVALTGDRKAGQPMASVYPFLRGAGLPDLVRIEDVDFSGVDLAFCALPHAT
SQSVIKALPADLKVVDLSADFRLRDPADYAKWYGKDHDAPALQKQAIYGLTEFYRDQIRDARLVAGTGCNAATGQFALRP
LIENGVVDLDDIIIDLICGVSGAGRALKENLLHAELSEGTHAYALGGTHRHLGEFDQEFSKVAGRKVEVQFTPHLAPFNR
GILATCYVKGDAQAIHATLTAAYRGEMFIEVLPFGAAPSTHDVRGTNYCHIGVVADRRSGRAQIVAALDNLCKGSSGQAV
QNANLMLGLEETAGLLGLGVFP
>Mature_341_residues
TKKIAILGASGYTGAELCRLIAGHPDMTIVALTGDRKAGQPMASVYPFLRGAGLPDLVRIEDVDFSGVDLAFCALPHATS
QSVIKALPADLKVVDLSADFRLRDPADYAKWYGKDHDAPALQKQAIYGLTEFYRDQIRDARLVAGTGCNAATGQFALRPL
IENGVVDLDDIIIDLICGVSGAGRALKENLLHAELSEGTHAYALGGTHRHLGEFDQEFSKVAGRKVEVQFTPHLAPFNRG
ILATCYVKGDAQAIHATLTAAYRGEMFIEVLPFGAAPSTHDVRGTNYCHIGVVADRRSGRAQIVAALDNLCKGSSGQAVQ
NANLMLGLEETAGLLGLGVFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=341, Percent_Identity=36.6568914956012, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6320913, Length=357, Percent_Identity=27.1708683473389, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_JANSC (Q28PV9)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510278.1
- ProteinModelPortal:   Q28PV9
- SMR:   Q28PV9
- STRING:   Q28PV9
- GeneID:   3934792
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2336
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   Q28PV9
- ProtClustDB:   PRK00436
- BioCyc:   JSP290400:JANN_2336-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 36441; Mature: 36310

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKIAILGASGYTGAELCRLIAGHPDMTIVALTGDRKAGQPMASVYPFLRGAGLPDLVR
CCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCEEE
IEDVDFSGVDLAFCALPHATSQSVIKALPADLKVVDLSADFRLRDPADYAKWYGKDHDAP
EECCCCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEECCCCEECCCHHHHHHCCCCCCCC
ALQKQAIYGLTEFYRDQIRDARLVAGTGCNAATGQFALRPLIENGVVDLDDIIIDLICGV
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCC
SGAGRALKENLLHAELSEGTHAYALGGTHRHLGEFDQEFSKVAGRKVEVQFTPHLAPFNR
CCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
GILATCYVKGDAQAIHATLTAAYRGEMFIEVLPFGAAPSTHDVRGTNYCHIGVVADRRSG
CEEEEEEECCCCCEEHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCC
RAQIVAALDNLCKGSSGQAVQNANLMLGLEETAGLLGLGVFP
HHHHHHHHHHHHCCCCCCEEECCCEEEEEHHHCCEEECCCCC
>Mature Secondary Structure 
TKKIAILGASGYTGAELCRLIAGHPDMTIVALTGDRKAGQPMASVYPFLRGAGLPDLVR
CCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCEEE
IEDVDFSGVDLAFCALPHATSQSVIKALPADLKVVDLSADFRLRDPADYAKWYGKDHDAP
EECCCCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEECCCCEECCCHHHHHHCCCCCCCC
ALQKQAIYGLTEFYRDQIRDARLVAGTGCNAATGQFALRPLIENGVVDLDDIIIDLICGV
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCC
SGAGRALKENLLHAELSEGTHAYALGGTHRHLGEFDQEFSKVAGRKVEVQFTPHLAPFNR
CCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
GILATCYVKGDAQAIHATLTAAYRGEMFIEVLPFGAAPSTHDVRGTNYCHIGVVADRRSG
CEEEEEEECCCCCEEHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCC
RAQIVAALDNLCKGSSGQAVQNANLMLGLEETAGLLGLGVFP
HHHHHHHHHHHHCCCCCCEEECCCEEEEEHHHCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA