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The map label for this gene is tsf

Identifier: 89054796

GI number: 89054796

Start: 2308961

End: 2309836

Strand: Reverse

Name: tsf

Synonym: Jann_2305

Alternate gene names: 89054796

Gene position: 2309836-2308961 (Counterclockwise)

Preceding gene: 89054797

Following gene: 89054794

Centisome position: 53.49

GC content: 62.33

Gene sequence:

>876_bases
ATGGCAATCACTGCAAGCATGGTAAAAGAACTGCGCGACACGACCGGCGCAGGCATGATGGACGCCAAGAAGGCATTGAC
CGAAACCGACGGTGACATGGACGCCGCCGTCGACTGGCTGCGGACCAAGGGCCTGGCGAAGGCGGCCAAGAAATCCGGCC
GCACGGCCGCCGAAGGTCTTGTGGCCGTTGCCGTCTCCGGCTCCACCGGCGTGGCTGTTGAAGTGAATTCCGAGACGGAT
TTCGTCGGCAAGAACGCCGAATTCCAGGAGATGGTTGCCGGTATCGCGCAGGTTGCCCTTGGTGCAGACGATACCGAGGC
GCTTCTGGCCGCCGACATGGGTGGCAAATCCGTCGCCGATACCGTCACTGCGAAAGTCGCCACCATCGGCGAGAACATGG
GCGTGCGCCGCATGGCGAAGCTGGAAGGCGATATCGTCGTCTCCTACGTCCACAACGCCGCCGCTGACGGCATGGGCAAG
ATCGGCGTTCTGATCGCCACCAAAGGCGGGGACGCGGGCTTTGCCAAGCAGGTCGCCATGCATGTGGCCGCCGTGAACCC
CGCGTCGCTGGATGAGGCCTCCGTCGATCCTGAGATGGTCGAGAAGGAGCGTCAGGTTCAGATCGACATCGCGCGGGAGA
GCGGCAAGCCCGAGCAGGTCATCGAAAAAATGATCGTGGGCCGCATGAAGAAGTACCTGTCCGAGATCACCCTCGTGAAC
CAGGCCTTCGTCGTGAACCCGGACCTGACCGTGGGCGAGGCCGCCAAAGAAGCCAGTGCCGAGATCACCGGTTTCGTGCG
CCTCGAAGTCGGCGAAGGCATCGAGAAGAAGGTCGAGAATTTCGCAGAAGAGGTGGCCAAGACCGCCAAGGGCTAA

Upstream 100 bases:

>100_bases
AACGCCAGCCGCCGAAGCGTAAATCCTTCGGATCACGGAACTGACATCAGGGCCCGGGCAACCGGGTCCGACCCATTCCC
AATTTCAGGAGACCCATGAC

Downstream 100 bases:

>100_bases
GTCCTTCCGCTTGGTAATTTAGTATGGGCAGGGGAGCGATCCTCTGCCCTTATTCCATGGCAGGACCACGCCTGCTGGGT
GGCGCCGCATCAATCGACTT

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MAITASMVKELRDTTGAGMMDAKKALTETDGDMDAAVDWLRTKGLAKAAKKSGRTAAEGLVAVAVSGSTGVAVEVNSETD
FVGKNAEFQEMVAGIAQVALGADDTEALLAADMGGKSVADTVTAKVATIGENMGVRRMAKLEGDIVVSYVHNAAADGMGK
IGVLIATKGGDAGFAKQVAMHVAAVNPASLDEASVDPEMVEKERQVQIDIARESGKPEQVIEKMIVGRMKKYLSEITLVN
QAFVVNPDLTVGEAAKEASAEITGFVRLEVGEGIEKKVENFAEEVAKTAKG

Sequences:

>Translated_291_residues
MAITASMVKELRDTTGAGMMDAKKALTETDGDMDAAVDWLRTKGLAKAAKKSGRTAAEGLVAVAVSGSTGVAVEVNSETD
FVGKNAEFQEMVAGIAQVALGADDTEALLAADMGGKSVADTVTAKVATIGENMGVRRMAKLEGDIVVSYVHNAAADGMGK
IGVLIATKGGDAGFAKQVAMHVAAVNPASLDEASVDPEMVEKERQVQIDIARESGKPEQVIEKMIVGRMKKYLSEITLVN
QAFVVNPDLTVGEAAKEASAEITGFVRLEVGEGIEKKVENFAEEVAKTAKG
>Mature_290_residues
AITASMVKELRDTTGAGMMDAKKALTETDGDMDAAVDWLRTKGLAKAAKKSGRTAAEGLVAVAVSGSTGVAVEVNSETDF
VGKNAEFQEMVAGIAQVALGADDTEALLAADMGGKSVADTVTAKVATIGENMGVRRMAKLEGDIVVSYVHNAAADGMGKI
GVLIATKGGDAGFAKQVAMHVAAVNPASLDEASVDPEMVEKERQVQIDIARESGKPEQVIEKMIVGRMKKYLSEITLVNQ
AFVVNPDLTVGEAAKEASAEITGFVRLEVGEGIEKKVENFAEEVAKTAKG

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=308, Percent_Identity=28.2467532467532, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI291084500, Length=329, Percent_Identity=27.0516717325228, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI291084502, Length=104, Percent_Identity=43.2692307692308, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI291084498, Length=104, Percent_Identity=43.2692307692308, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1786366, Length=290, Percent_Identity=50, Blast_Score=263, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17561440, Length=294, Percent_Identity=30.6122448979592, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI19921466, Length=308, Percent_Identity=27.2727272727273, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_JANSC (Q28PZ0)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510247.1
- ProteinModelPortal:   Q28PZ0
- SMR:   Q28PZ0
- STRING:   Q28PZ0
- GeneID:   3934761
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2305
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q28PZ0
- ProtClustDB:   PRK09377
- BioCyc:   JSP290400:JANN_2305-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 30261; Mature: 30130

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITASMVKELRDTTGAGMMDAKKALTETDGDMDAAVDWLRTKGLAKAAKKSGRTAAEGL
CCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCE
VAVAVSGSTGVAVEVNSETDFVGKNAEFQEMVAGIAQVALGADDTEALLAADMGGKSVAD
EEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHH
TVTAKVATIGENMGVRRMAKLEGDIVVSYVHNAAADGMGKIGVLIATKGGDAGFAKQVAM
HHHHHHHHHCCCCCHHHHHHHCCCEEEEEHHHHHCCCCCCEEEEEEECCCCCHHHHHHHH
HVAAVNPASLDEASVDPEMVEKERQVQIDIARESGKPEQVIEKMIVGRMKKYLSEITLVN
HHHHCCCCCCCCCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QAFVVNPDLTVGEAAKEASAEITGFVRLEVGEGIEKKVENFAEEVAKTAKG
CEEEECCCCCCCHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AITASMVKELRDTTGAGMMDAKKALTETDGDMDAAVDWLRTKGLAKAAKKSGRTAAEGL
CCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCE
VAVAVSGSTGVAVEVNSETDFVGKNAEFQEMVAGIAQVALGADDTEALLAADMGGKSVAD
EEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHH
TVTAKVATIGENMGVRRMAKLEGDIVVSYVHNAAADGMGKIGVLIATKGGDAGFAKQVAM
HHHHHHHHHCCCCCHHHHHHHCCCEEEEEHHHHHCCCCCCEEEEEEECCCCCHHHHHHHH
HVAAVNPASLDEASVDPEMVEKERQVQIDIARESGKPEQVIEKMIVGRMKKYLSEITLVN
HHHHCCCCCCCCCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QAFVVNPDLTVGEAAKEASAEITGFVRLEVGEGIEKKVENFAEEVAKTAKG
CEEEECCCCCCCHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA